Homo sapiens

0 known processes

EFTUD2

elongation factor Tu GTP binding domain containing 2

(Aliases: Snrp116,Snu114,U5-116KD,KIAA0031,DKFZp686E24196,FLJ44695)

EFTUD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna processing GO:0006397 133 0.994
Yeast
post embryonic development GO:0009791 2 0.980
Worm
spliceosomal snrnp assembly GO:0000387 28 0.978
Yeast
mrna splicing via spliceosome GO:0000398 89 0.972
Yeast
mrna metabolic process GO:0016071 175 0.972
Yeast
regulation of meiotic cell cycle GO:0051445 4 0.965
rna processing GO:0006396 255 0.896
Yeast
regulation of meiosis GO:0040020 3 0.871
female gamete generation GO:0007292 2 0.856
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.832
Yeast
rna splicing GO:0008380 131 0.809
Yeast
cellular macromolecular complex assembly GO:0034622 324 0.770
Yeast Worm
ribonucleoprotein complex subunit organization GO:0071826 81 0.760
Yeast
rna splicing via transesterification reactions GO:0000375 90 0.751
Yeast
spliceosomal tri snrnp complex assembly GO:0000244 7 0.723
Yeast
spliceosomal complex assembly GO:0000245 17 0.701
oogenesis GO:0048477 2 0.631
behavior GO:0007610 112 0.592
ossification GO:0001503 121 0.573
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.524
regulation of astrocyte differentiation GO:0048710 3 0.501
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.476
enzyme linked receptor protein signaling pathway GO:0007167 303 0.432
regulation of cell cycle process GO:0010564 266 0.419
microtubule cytoskeleton organization GO:0000226 176 0.417
purine nucleotide catabolic process GO:0006195 405 0.415
Yeast
dna integrity checkpoint GO:0031570 71 0.402
osteoblast differentiation GO:0001649 92 0.379
organelle fission GO:0048285 149 0.373
purine ribonucleotide catabolic process GO:0009154 404 0.372
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.340
nucleoside catabolic process GO:0009164 408 0.335
Yeast
muscle organ morphogenesis GO:0048644 19 0.324
receptor mediated endocytosis GO:0006898 84 0.307
meiotic cell cycle GO:0051321 13 0.301
ribonucleoprotein complex assembly GO:0022618 78 0.297
Yeast
regulation of cell division GO:0051302 116 0.296
ribonucleoside triphosphate metabolic process GO:0009199 412 0.288
Yeast
sex differentiation GO:0007548 45 0.284
cell development GO:0048468 328 0.263
Worm
cytokine production GO:0001816 247 0.263
rna localization GO:0006403 41 0.255
muscle structure development GO:0061061 98 0.252
Worm
reproductive process GO:0022414 106 0.251
lipid biosynthetic process GO:0008610 177 0.245
regulation of system process GO:0044057 101 0.238
nuclear division GO:0000280 128 0.229
defense response GO:0006952 315 0.224
reproductive system development GO:0061458 56 0.214
chordate embryonic development GO:0043009 34 0.208
microtubule based process GO:0007017 210 0.206
oocyte differentiation GO:0009994 2 0.205
anterior posterior axis specification GO:0009948 2 0.200
negative regulation of catalytic activity GO:0043086 335 0.200
immune system development GO:0002520 195 0.195
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.194
cell division GO:0051301 168 0.193
mapk cascade GO:0000165 288 0.193
Fly
atp catabolic process GO:0006200 157 0.192
posttranscriptional regulation of gene expression GO:0010608 213 0.191
developmental process involved in reproduction GO:0003006 66 0.189
reproductive structure development GO:0048608 55 0.179
growth GO:0040007 202 0.178
Worm
single organism reproductive process GO:0044702 98 0.172
endocytosis GO:0006897 159 0.170
regulation of mrna splicing via spliceosome GO:0048024 32 0.161
meiotic nuclear division GO:0007126 10 0.160
embryo development GO:0009790 123 0.157
Worm
embryonic placenta development GO:0001892 1 0.155
purine nucleoside monophosphate metabolic process GO:0009126 186 0.154
negative regulation of oxidative stress induced cell death GO:1903202 17 0.154
regulation of cell motility GO:2000145 299 0.151
cardiovascular system development GO:0072358 262 0.149
regulation of cellular response to stress GO:0080135 244 0.146
vesicle mediated transport GO:0016192 371 0.141
mitotic cell cycle process GO:1903047 286 0.140
cellular response to growth factor stimulus GO:0071363 197 0.135
oxidation reduction process GO:0055114 396 0.130
organophosphate catabolic process GO:0046434 430 0.129
Yeast
taxis GO:0042330 157 0.129
signal transduction by phosphorylation GO:0023014 297 0.127
Fly
circulatory system development GO:0072359 262 0.124
positive regulation of cytokine production GO:0001819 167 0.124
generation of neurons GO:0048699 152 0.119
negative regulation of phosphate metabolic process GO:0045936 267 0.119
immune response GO:0006955 307 0.117
purine nucleoside triphosphate catabolic process GO:0009146 392 0.110
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 158 0.110
epithelium development GO:0060429 227 0.109
negative regulation of phosphorus metabolic process GO:0010563 267 0.104
cellular response to endogenous stimulus GO:0071495 336 0.100
regulation of cellular component movement GO:0051270 334 0.099
nucleoside monophosphate metabolic process GO:0009123 191 0.096
purine ribonucleoside catabolic process GO:0046130 398 0.094
Yeast
dna damage checkpoint GO:0000077 68 0.094
ribonucleoside monophosphate catabolic process GO:0009158 158 0.093
mechanosensory behavior GO:0007638 4 0.093
ribosome biogenesis GO:0042254 48 0.088
maintenance of location GO:0051235 112 0.088
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.088
ncrna metabolic process GO:0034660 108 0.087
positive regulation of phosphorylation GO:0042327 394 0.086
Fly
myeloid cell homeostasis GO:0002262 34 0.084
anterior posterior axis specification embryo GO:0008595 2 0.084
regulation of glial cell differentiation GO:0045685 3 0.083
lipid metabolic process GO:0006629 381 0.080
ribonucleotide catabolic process GO:0009261 405 0.079
Yeast
nucleoside triphosphate catabolic process GO:0009143 394 0.078
Yeast
glycosyl compound catabolic process GO:1901658 413 0.076
Yeast
response to other organism GO:0051707 261 0.076
somitogenesis GO:0001756 2 0.075
negative regulation of intracellular signal transduction GO:1902532 183 0.074
mitotic cell cycle GO:0000278 326 0.072
defense response to bacterium GO:0042742 63 0.072
wound healing GO:0042060 115 0.072
i kappab kinase nf kappab signaling GO:0007249 166 0.071
mitotic nuclear division GO:0007067 119 0.070
gonad development GO:0008406 34 0.068
ribonucleoside monophosphate metabolic process GO:0009161 187 0.068
response to transforming growth factor beta GO:0071559 94 0.066
positive regulation of developmental process GO:0051094 314 0.065
oocyte development GO:0048599 1 0.065
tissue morphogenesis GO:0048729 96 0.065
negative regulation of phosphorylation GO:0042326 174 0.064
regulation of behavior GO:0050795 82 0.064
intrinsic apoptotic signaling pathway GO:0097193 127 0.064
atp metabolic process GO:0046034 176 0.063
neurogenesis GO:0022008 169 0.063
regulation of cytokine production GO:0001817 232 0.062
negative regulation of cellular response to oxidative stress GO:1900408 18 0.061
response to inorganic substance GO:0010035 127 0.059
regulation of mrna metabolic process GO:1903311 53 0.057
negative regulation of apoptotic signaling pathway GO:2001234 97 0.057
negative regulation of protein metabolic process GO:0051248 391 0.057
multicellular organismal reproductive process GO:0048609 40 0.056
reproduction GO:0000003 63 0.054
Worm
embryo development ending in birth or egg hatching GO:0009792 34 0.053
Worm
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.053
regulation of oxidative stress induced cell death GO:1903201 24 0.051
anatomical structure homeostasis GO:0060249 100 0.051
response to external biotic stimulus GO:0043207 261 0.051
regulation of mapk cascade GO:0043408 262 0.050
Fly
morphogenesis of an epithelium GO:0002009 60 0.048
single organism nuclear import GO:1902593 104 0.047
rrna processing GO:0006364 35 0.046
nucleoside monophosphate catabolic process GO:0009125 159 0.046
astrocyte differentiation GO:0048708 4 0.045
nucleocytoplasmic transport GO:0006913 176 0.044
positive regulation of programmed cell death GO:0043068 249 0.044
nucleotide catabolic process GO:0009166 408 0.043
Yeast
apoptotic signaling pathway GO:0097190 268 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
Yeast
nucleoside phosphate catabolic process GO:1901292 412 0.042
Yeast
negative regulation of transferase activity GO:0051348 124 0.042
ribonucleoprotein complex biogenesis GO:0022613 116 0.042
Yeast
regulation of cellular response to oxidative stress GO:1900407 26 0.041
multi organism reproductive process GO:0044703 54 0.041
positive regulation of mapk cascade GO:0043410 190 0.041
Fly
gastrulation with mouth forming second GO:0001702 1 0.041
positive regulation of neural precursor cell proliferation GO:2000179 2 0.040
regeneration GO:0031099 4 0.039
angiogenesis GO:0001525 147 0.039
dna repair GO:0006281 198 0.039
nervous system development GO:0007399 293 0.038
establishment of protein localization to organelle GO:0072594 172 0.038
chromatin assembly or disassembly GO:0006333 78 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.038
response to abiotic stimulus GO:0009628 336 0.037
regulation of locomotion GO:0040012 329 0.037
ras protein signal transduction GO:0007265 73 0.037
Fly
central nervous system development GO:0007417 123 0.037
organ morphogenesis GO:0009887 147 0.036
protein targeting GO:0006605 187 0.036
purine containing compound catabolic process GO:0072523 411 0.036
Yeast
negative regulation of protein phosphorylation GO:0001933 140 0.036
multicellular organism reproduction GO:0032504 42 0.036
dna recombination GO:0006310 77 0.035
lipid localization GO:0010876 106 0.035
blood vessel development GO:0001568 172 0.035
blastoderm segmentation GO:0007350 2 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
Yeast
sensory perception of light stimulus GO:0050953 35 0.034
negative regulation of multicellular organismal process GO:0051241 317 0.034
multi multicellular organism process GO:0044706 18 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
Yeast
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.032
innate immune response GO:0045087 178 0.032
regulation of protein serine threonine kinase activity GO:0071900 179 0.032
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.031
tumor necrosis factor production GO:0032640 43 0.031
response to nutrient levels GO:0031667 81 0.031
thymus development GO:0048538 3 0.031
regulation of kinase activity GO:0043549 314 0.031
purine nucleoside triphosphate metabolic process GO:0009144 412 0.030
Yeast
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.030
Fly
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.030
positive regulation of cell development GO:0010720 92 0.029
negative regulation of cell death GO:0060548 345 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
Yeast
regulation of response to oxidative stress GO:1902882 26 0.029
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.028
vasculature development GO:0001944 181 0.028
sexual reproduction GO:0019953 37 0.028
positive regulation of cell death GO:0010942 263 0.028
segmentation GO:0035282 4 0.028
humoral immune response GO:0006959 49 0.028
response to hormone GO:0009725 175 0.028
visual perception GO:0007601 27 0.028
purine nucleoside catabolic process GO:0006152 398 0.027
Yeast
regulation of rna stability GO:0043487 23 0.027
positive regulation of peptidase activity GO:0010952 88 0.026
regulation of erk1 and erk2 cascade GO:0070372 99 0.026
Fly
single organismal cell cell adhesion GO:0016337 148 0.026
maintenance of protein location in cell GO:0032507 56 0.026
muscle organ development GO:0007517 56 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.025
negative regulation of protein kinase activity GO:0006469 98 0.025
muscle system process GO:0003012 81 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.024
Yeast
response to biotic stimulus GO:0009607 276 0.024
cellular response to oxygen containing compound GO:1901701 276 0.024
genitalia development GO:0048806 10 0.024
response to oxidative stress GO:0006979 121 0.024
regulation of immune response GO:0050776 201 0.023
cellular component disassembly GO:0022411 92 0.023
dna geometric change GO:0032392 32 0.023
tissue homeostasis GO:0001894 63 0.023
regulation of lipid biosynthetic process GO:0046890 47 0.023
cell adhesion GO:0007155 325 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.023
intracellular mrna localization GO:0008298 1 0.023
neuromuscular junction development GO:0007528 3 0.023
alternative mrna splicing via spliceosome GO:0000380 27 0.023
cell proliferation involved in kidney development GO:0072111 3 0.022
cell death in response to oxidative stress GO:0036473 29 0.022
cell cycle checkpoint GO:0000075 117 0.022
multi organism behavior GO:0051705 14 0.021
response to mechanical stimulus GO:0009612 51 0.021
regulation of dna metabolic process GO:0051052 153 0.021
protein import GO:0017038 130 0.021
regulation of transcription factor import into nucleus GO:0042990 39 0.020
divalent metal ion transport GO:0070838 152 0.020
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
regulation of muscle system process GO:0090257 53 0.020
regulation of mrna processing GO:0050684 48 0.020
carbohydrate metabolic process GO:0005975 207 0.020
response to organic cyclic compound GO:0014070 204 0.020
negative regulation of response to oxidative stress GO:1902883 18 0.020
leukocyte activation GO:0045321 164 0.019
protein import into nucleus GO:0006606 104 0.019
response to organonitrogen compound GO:0010243 156 0.019
mitochondrion organization GO:0007005 156 0.019
regulation of signal transduction by p53 class mediator GO:1901796 26 0.019
single organism cellular localization GO:1902580 332 0.019
synaptic transmission GO:0007268 61 0.019
regulation of anatomical structure size GO:0090066 101 0.019
multicellular organismal homeostasis GO:0048871 67 0.019
regulation of oocyte development GO:0060281 1 0.019
response to wounding GO:0009611 168 0.018
response to virus GO:0009615 126 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
dna dependent dna replication GO:0006261 44 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
Yeast
protein polymerization GO:0051258 71 0.018
cell morphogenesis GO:0000902 296 0.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.017
cell cell signaling GO:0007267 155 0.017
positive regulation of locomotion GO:0040017 186 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
heart development GO:0007507 95 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
homeostasis of number of cells GO:0048872 40 0.016
regulation of atp metabolic process GO:1903578 29 0.016
dna conformation change GO:0071103 113 0.016
regulation of tumor necrosis factor production GO:0032680 43 0.016
cell chemotaxis GO:0060326 112 0.016
lymphocyte activation GO:0046649 133 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
negative regulation of apoptotic process GO:0043066 316 0.015
response to oxygen containing compound GO:1901700 369 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
system process GO:0003008 349 0.015
biological adhesion GO:0022610 331 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
myeloid cell differentiation GO:0030099 117 0.015
divalent inorganic cation transport GO:0072511 158 0.015
neural tube patterning GO:0021532 2 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
regulation of protein kinase activity GO:0045859 289 0.014
positive regulation of wound healing GO:0090303 20 0.014
negative regulation of cell development GO:0010721 48 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of cell development GO:0060284 161 0.014
regulation of ion transport GO:0043269 189 0.014
tripartite regional subdivision GO:0007351 2 0.014
regulation of heart growth GO:0060420 4 0.014
mrna stabilization GO:0048255 18 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
Fly
multi organism cellular process GO:0044764 156 0.014
positive regulation of cell migration GO:0030335 172 0.014
cellular response to lipid GO:0071396 127 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.013
meiosis i GO:0007127 4 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
regulation of homeostatic process GO:0032844 121 0.013
cellular protein catabolic process GO:0044257 261 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
response to starvation GO:0042594 59 0.013
regulation of chemotaxis GO:0050920 74 0.013
regulation of wound healing GO:0061041 56 0.013
regulation of protein localization GO:0032880 296 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
muscle cell cellular homeostasis GO:0046716 3 0.013
determination of adult lifespan GO:0008340 2 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
regulation of axon regeneration GO:0048679 1 0.012
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.012
meiotic chromosome segregation GO:0045132 4 0.012
regulation of immune effector process GO:0002697 91 0.012
maturation of 5 8s rrna GO:0000460 8 0.012
cellular response to oxidative stress GO:0034599 85 0.012
single organism behavior GO:0044708 28 0.012
neuron projection regeneration GO:0031102 1 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
positive regulation of protein import into nucleus GO:0042307 46 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
dna templated transcription elongation GO:0006354 25 0.012
gene silencing by rna GO:0031047 26 0.012
maintenance of protein location GO:0045185 57 0.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.011
protein catabolic process GO:0030163 325 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
molting cycle GO:0042303 28 0.011
Worm
organelle assembly GO:0070925 176 0.011
Worm
negative regulation of cell proliferation GO:0008285 228 0.011
translation GO:0006412 132 0.011
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.011
alcohol metabolic process GO:0006066 114 0.011
ameboidal type cell migration GO:0001667 135 0.011
viral process GO:0016032 146 0.011
regulation of muscle hypertrophy GO:0014743 10 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
pattern specification process GO:0007389 43 0.011
intracellular protein transport GO:0006886 270 0.011
ncrna processing GO:0034470 83 0.011
cytokine metabolic process GO:0042107 38 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.011
coenzyme metabolic process GO:0006732 65 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
negative regulation of protein modification process GO:0031400 200 0.011
actin filament based movement GO:0030048 17 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
positive regulation of cytokine biosynthetic process GO:0042108 25 0.010
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.010
nucleus localization GO:0051647 1 0.010
cellular response to reactive oxygen species GO:0034614 50 0.010
rna interference GO:0016246 4 0.010
interleukin 1 beta production GO:0032611 22 0.010
neurological system process GO:0050877 163 0.010

EFTUD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.979
eye and adnexa disease DOID:1492 150 0.979
nervous system disease DOID:863 431 0.979
retinal disease DOID:5679 118 0.804
eye disease DOID:5614 149 0.804
retinal degeneration DOID:8466 89 0.532
retinitis pigmentosa DOID:10584 51 0.165
neuropathy DOID:870 52 0.122
neuromuscular disease DOID:440 38 0.030
central nervous system disease DOID:331 186 0.025
charcot marie tooth disease type 2 DOID:0050539 15 0.025
charcot marie tooth disease DOID:10595 33 0.025
myopathy DOID:423 104 0.017
muscular disease DOID:0080000 114 0.017
heart disease DOID:114 68 0.017
cardiomyopathy DOID:0050700 50 0.017
dilated cardiomyopathy DOID:12930 32 0.017
intrinsic cardiomyopathy DOID:0060036 50 0.017
cardiovascular system disease DOID:1287 106 0.017
musculoskeletal system disease DOID:17 223 0.017
muscle tissue disease DOID:66 113 0.017
disease of cellular proliferation DOID:14566 174 0.014
neurodegenerative disease DOID:1289 102 0.012
usher syndrome DOID:0050439 12 0.011