Homo sapiens

106 known processes

TLE1

transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

(Aliases: ESG,GRG1,ESG1)

TLE1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 50 0.914
hair follicle morphogenesis GO:0031069 2 0.885
cellular ketone metabolic process GO:0042180 80 0.662
tissue morphogenesis GO:0048729 96 0.617
regulation of cellular amino acid metabolic process GO:0006521 6 0.607
female gamete generation GO:0007292 2 0.577
Worm
negative regulation of interleukin 5 production GO:0032714 3 0.548
embryonic morphogenesis GO:0048598 85 0.531
kidney development GO:0001822 53 0.450
amine metabolic process GO:0009308 44 0.450
epidermis morphogenesis GO:0048730 3 0.411
negative regulation of developmental process GO:0051093 247 0.409
regulation of myeloid cell differentiation GO:0045637 81 0.391
cellular amine metabolic process GO:0044106 41 0.390
cellular amino acid metabolic process GO:0006520 116 0.373
cell development GO:0048468 328 0.366
Worm Fly
regulation of leukocyte differentiation GO:1902105 61 0.363
oogenesis GO:0048477 2 0.352
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.349
urogenital system development GO:0001655 65 0.337
hindbrain development GO:0030902 3 0.320
positive regulation of cellular catabolic process GO:0031331 284 0.277
lymphocyte activation GO:0046649 133 0.263
histone h3 acetylation GO:0043966 45 0.260
post embryonic development GO:0009791 2 0.246
Worm
skeletal system development GO:0001501 79 0.245
anatomical structure regression GO:0060033 1 0.244
immune system development GO:0002520 195 0.244
neuron development GO:0048666 113 0.230
Worm Fly
neurogenesis GO:0022008 169 0.225
Worm Fly
positive regulation of cell death GO:0010942 263 0.215
positive regulation of myeloid cell differentiation GO:0045639 39 0.215
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.214
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.213
nervous system development GO:0007399 293 0.212
Worm Fly
negative regulation of cell differentiation GO:0045596 171 0.202
forelimb morphogenesis GO:0035136 4 0.200
myeloid cell differentiation GO:0030099 117 0.197
regulation of apoptotic signaling pathway GO:2001233 175 0.196
mesodermal cell fate commitment GO:0001710 2 0.195
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.194
chemotaxis GO:0006935 157 0.193
ossification GO:0001503 121 0.193
organ morphogenesis GO:0009887 147 0.192
enzyme linked receptor protein signaling pathway GO:0007167 303 0.183
secretion GO:0046903 254 0.179
positive regulation of catabolic process GO:0009896 310 0.175
regeneration GO:0031099 4 0.173
taxis GO:0042330 157 0.172
patterning of blood vessels GO:0001569 2 0.171
regulation of hormone secretion GO:0046883 57 0.168
cellular response to organic cyclic compound GO:0071407 127 0.161
osteoblast differentiation GO:0001649 92 0.161
cellular component morphogenesis GO:0032989 314 0.153
Worm Fly
positive regulation of programmed cell death GO:0043068 249 0.153
cell proliferation involved in heart valve development GO:2000793 1 0.152
glycosyl compound catabolic process GO:1901658 413 0.152
negative regulation of multicellular organismal process GO:0051241 317 0.151
circulatory system development GO:0072359 262 0.150
sulfur compound metabolic process GO:0006790 101 0.148
epithelium development GO:0060429 227 0.147
neuroblast proliferation GO:0007405 4 0.147
sulfur compound biosynthetic process GO:0044272 38 0.144
salivary gland morphogenesis GO:0007435 4 0.142
diterpenoid biosynthetic process GO:0016102 2 0.140
forebrain generation of neurons GO:0021872 3 0.138
apoptotic signaling pathway GO:0097190 268 0.138
somitogenesis GO:0001756 2 0.133
posttranscriptional regulation of gene expression GO:0010608 213 0.133
hemopoiesis GO:0030097 180 0.132
positive regulation of cell proliferation GO:0008284 301 0.132
hematopoietic or lymphoid organ development GO:0048534 186 0.130
leukocyte differentiation GO:0002521 98 0.125
branching morphogenesis of an epithelial tube GO:0048754 19 0.123
regulation of kinase activity GO:0043549 314 0.122
positive regulation of kinase activity GO:0033674 204 0.122
regulation of secretion by cell GO:1903530 177 0.118
negative regulation of cell proliferation GO:0008285 228 0.116
neural crest cell development GO:0014032 3 0.114
negative regulation of myeloid cell differentiation GO:0045638 42 0.114
regulation of nucleotide catabolic process GO:0030811 205 0.112
regulation of protein serine threonine kinase activity GO:0071900 179 0.108
myeloid leukocyte differentiation GO:0002573 60 0.105
forebrain neuron differentiation GO:0021879 3 0.105
chromatin organization GO:0006325 351 0.104
negative regulation of cell motility GO:2000146 104 0.103
regulation of cell differentiation GO:0045595 393 0.103
Worm
rna splicing GO:0008380 131 0.102
tongue development GO:0043586 1 0.102
stem cell division GO:0017145 2 0.101
hair cycle GO:0042633 28 0.100
morphogenesis of an epithelium GO:0002009 60 0.100
somatic stem cell division GO:0048103 1 0.099
regulation of protein kinase activity GO:0045859 289 0.098
cytoplasmic transport GO:0016482 379 0.097
mesenchymal cell development GO:0014031 50 0.094
epithelial cell differentiation GO:0030855 141 0.091
positive regulation of immune system process GO:0002684 283 0.089
oocyte differentiation GO:0009994 2 0.089
positive regulation of developmental process GO:0051094 314 0.088
positive regulation of cell differentiation GO:0045597 211 0.088
neuroblast division GO:0055057 1 0.085
extrinsic apoptotic signaling pathway GO:0097191 119 0.084
central nervous system development GO:0007417 123 0.084
rna processing GO:0006396 255 0.084
gtp catabolic process GO:0006184 237 0.084
positive regulation of apoptotic process GO:0043065 246 0.084
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.084
segmentation GO:0035282 4 0.083
histone modification GO:0016570 251 0.083
negative regulation of phosphate metabolic process GO:0045936 267 0.083
multicellular organismal response to stress GO:0033555 1 0.082
negative regulation of myeloid leukocyte differentiation GO:0002762 16 0.082
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.081
regulation of secretion GO:0051046 194 0.081
peptidyl tyrosine phosphorylation GO:0018108 170 0.080
nucleotide catabolic process GO:0009166 408 0.080
negative regulation of ruffle assembly GO:1900028 3 0.079
protein acylation GO:0043543 138 0.078
rna interference GO:0016246 4 0.078
pharynx development GO:0060465 1 0.077
regulation of cell growth GO:0001558 135 0.076
reproductive process GO:0022414 106 0.076
Worm
positive regulation of cellular component organization GO:0051130 376 0.075
response to organic cyclic compound GO:0014070 204 0.075
regulation of cellular response to stress GO:0080135 244 0.074
developmental programmed cell death GO:0010623 3 0.073
anatomical structure formation involved in morphogenesis GO:0048646 284 0.072
viral gene expression GO:0019080 35 0.072
negative regulation of programmed cell death GO:0043069 321 0.071
regulation of myeloid leukocyte differentiation GO:0002761 39 0.070
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.070
regulation of protein localization GO:0032880 296 0.070
negative regulation of cellular component movement GO:0051271 106 0.069
hormone secretion GO:0046879 65 0.069
secretion by cell GO:0032940 226 0.069
cyclic nucleotide metabolic process GO:0009187 82 0.068
regulation of wnt signaling pathway GO:0030111 123 0.068
Human Fly
cell morphogenesis GO:0000902 296 0.067
Worm Fly
internal peptidyl lysine acetylation GO:0018393 97 0.066
embryonic forelimb morphogenesis GO:0035115 4 0.065
lipid biosynthetic process GO:0008610 177 0.065
internal protein amino acid acetylation GO:0006475 101 0.063
nucleoside phosphate catabolic process GO:1901292 412 0.063
stem cell differentiation GO:0048863 93 0.062
negative regulation of binding GO:0051100 57 0.062
neuron projection regeneration GO:0031102 1 0.061
chemical homeostasis GO:0048878 306 0.060
nucleocytoplasmic transport GO:0006913 176 0.059
cardiovascular system development GO:0072358 262 0.058
system process GO:0003008 349 0.058
generation of neurons GO:0048699 152 0.057
Worm Fly
cellular macromolecular complex assembly GO:0034622 324 0.056
mitotic cell cycle GO:0000278 326 0.056
cell type specific apoptotic process GO:0097285 125 0.056
negative regulation of cellular amine metabolic process GO:0033239 3 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.055
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.054
photoreceptor cell differentiation GO:0046530 2 0.054
organic acid biosynthetic process GO:0016053 97 0.054
nucleoside triphosphate catabolic process GO:0009143 394 0.054
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.054
positive regulation of protein phosphorylation GO:0001934 313 0.053
regulation of endopeptidase activity GO:0052548 170 0.053
nerve development GO:0021675 4 0.053
response to wounding GO:0009611 168 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.052
gland morphogenesis GO:0022612 8 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
positive regulation of apoptotic signaling pathway GO:2001235 70 0.051
interspecies interaction between organisms GO:0044419 156 0.051
cellular response to cytokine stimulus GO:0071345 181 0.051
regulation of cellular component biogenesis GO:0044087 281 0.051
regulation of system process GO:0044057 101 0.051
regulation of lipid metabolic process GO:0019216 96 0.051
limb morphogenesis GO:0035108 16 0.050
regulation of feeding behavior GO:0060259 3 0.050
regulation of smooth muscle cell proliferation GO:0048660 28 0.050
response to hyperoxia GO:0055093 4 0.050
positive regulation of leukocyte activation GO:0002696 80 0.050
negative regulation of phosphorus metabolic process GO:0010563 267 0.049
lipid metabolic process GO:0006629 381 0.049
negative regulation of gliogenesis GO:0014014 3 0.049
positive regulation of cellular amine metabolic process GO:0033240 7 0.049
positive regulation of mrna metabolic process GO:1903313 19 0.049
apoptotic process involved in morphogenesis GO:0060561 3 0.048
positive regulation of cell migration GO:0030335 172 0.048
metencephalon development GO:0022037 2 0.048
single organism reproductive process GO:0044702 98 0.047
Worm
neural tube patterning GO:0021532 2 0.047
regulation of transferase activity GO:0051338 355 0.047
bmp signaling pathway GO:0030509 49 0.047
glycoprotein metabolic process GO:0009100 110 0.047
histone h4 acetylation GO:0043967 47 0.047
embryonic viscerocranium morphogenesis GO:0048703 1 0.047
stem cell development GO:0048864 69 0.047
hypothalamus development GO:0021854 1 0.046
intracellular protein transport GO:0006886 270 0.046
negative regulation of cell growth GO:0030308 83 0.046
negative regulation of hydrolase activity GO:0051346 182 0.046
negative regulation of phosphatase activity GO:0010923 61 0.046
protein methylation GO:0006479 74 0.045
cell growth GO:0016049 160 0.043
cell activation GO:0001775 213 0.043
wnt signaling pathway GO:0016055 156 0.043
Human Fly
neuronal stem cell division GO:0036445 1 0.043
negative regulation of apoptotic signaling pathway GO:2001234 97 0.042
heparan sulfate proteoglycan metabolic process GO:0030201 12 0.042
appendage morphogenesis GO:0035107 16 0.042
multi organism cellular process GO:0044764 156 0.042
limbic system development GO:0021761 3 0.042
smooth muscle cell proliferation GO:0048659 28 0.041
signal release GO:0023061 70 0.041
cellular glucan metabolic process GO:0006073 22 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.040
oxidation reduction process GO:0055114 396 0.040
regulation of response to external stimulus GO:0032101 222 0.040
neuroendocrine cell differentiation GO:0061101 2 0.040
response to lipid GO:0033993 206 0.040
regulation of cell cycle GO:0051726 393 0.040
response to axon injury GO:0048678 1 0.040
cranial nerve development GO:0021545 4 0.039
positive regulation of protein kinase activity GO:0045860 190 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
growth GO:0040007 202 0.039
carboxylic acid biosynthetic process GO:0046394 97 0.039
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.039
regulation of locomotion GO:0040012 329 0.039
protein alkylation GO:0008213 74 0.039
negative regulation of cell migration GO:0030336 102 0.038
muscle structure development GO:0061061 98 0.038
regulation of peptidase activity GO:0052547 180 0.038
pattern specification process GO:0007389 43 0.038
dephosphorylation GO:0016311 209 0.037
regulation of hormone levels GO:0010817 125 0.037
negative regulation of leukocyte differentiation GO:1902106 24 0.037
cell division GO:0051301 168 0.037
appendage development GO:0048736 23 0.037
small gtpase mediated signal transduction GO:0007264 78 0.037
neuron differentiation GO:0030182 138 0.037
Worm Fly
cell fate commitment GO:0045165 27 0.037
Fly
oocyte development GO:0048599 1 0.036
positive regulation of stem cell differentiation GO:2000738 29 0.036
embryo development GO:0009790 123 0.036
Worm
cellular lipid metabolic process GO:0044255 303 0.035
cartilage development GO:0051216 31 0.035
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.035
biological adhesion GO:0022610 331 0.035
chromatin modification GO:0016568 298 0.035
axon regeneration GO:0031103 1 0.035
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.035
skin development GO:0043588 76 0.035
lymphocyte proliferation GO:0046651 70 0.034
regulation of nucleoside metabolic process GO:0009118 209 0.034
negative regulation of phosphorylation GO:0042326 174 0.034
developmental growth GO:0048589 48 0.034
histone acetylation GO:0016573 93 0.034
protein maturation GO:0051604 233 0.034
compound eye development GO:0048749 1 0.034
negative regulation of transferase activity GO:0051348 124 0.034
regulation of gtpase activity GO:0043087 180 0.034
determination of adult lifespan GO:0008340 2 0.033
terpenoid biosynthetic process GO:0016114 2 0.033
renal system development GO:0072001 63 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.033
cell projection organization GO:0030030 252 0.033
Worm Fly
cell cell signaling GO:0007267 155 0.033
Worm Fly
regulation of excretion GO:0044062 1 0.033
monocarboxylic acid biosynthetic process GO:0072330 67 0.033
protein acetylation GO:0006473 116 0.033
regulation of cell motility GO:2000145 299 0.032
single organism cell adhesion GO:0098602 179 0.032
regulation of cell cell adhesion GO:0022407 57 0.032
purine containing compound catabolic process GO:0072523 411 0.032
positive regulation of transport GO:0051050 336 0.032
regulation of stem cell differentiation GO:2000736 56 0.032
regulation of cellular component movement GO:0051270 334 0.031
ovulation cycle process GO:0022602 9 0.031
negative regulation of protein phosphorylation GO:0001933 140 0.031
regulation of mapk cascade GO:0043408 262 0.031
positive regulation of nucleotide metabolic process GO:0045981 230 0.031
tube morphogenesis GO:0035239 95 0.031
epithelial tube morphogenesis GO:0060562 38 0.031
limb development GO:0060173 23 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
blood vessel development GO:0001568 172 0.031
embryonic organ development GO:0048568 36 0.030
viral process GO:0016032 146 0.030
regulation of binding GO:0051098 111 0.030
negative regulation of apoptotic process GO:0043066 316 0.030
cytokine production GO:0001816 247 0.029
tissue regeneration GO:0042246 3 0.029
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.029
small molecule biosynthetic process GO:0044283 157 0.029
organic acid catabolic process GO:0016054 71 0.029
covalent chromatin modification GO:0016569 254 0.029
cell part morphogenesis GO:0032990 137 0.029
Worm Fly
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
brain development GO:0007420 97 0.029
regulation of glial cell proliferation GO:0060251 4 0.029
immune response GO:0006955 307 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
positive regulation of cell adhesion GO:0045785 84 0.028
calcium ion transport GO:0006816 147 0.028
mitotic cell cycle process GO:1903047 286 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
regulation of lipid biosynthetic process GO:0046890 47 0.028
polysaccharide metabolic process GO:0005976 33 0.028
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.028
Worm Fly
modification of morphology or physiology of other organism GO:0035821 43 0.028
regulation of cell cycle process GO:0010564 266 0.027
regulation of epithelial to mesenchymal transition GO:0010717 37 0.027
negative regulation of interleukin 4 production GO:0032713 3 0.027
camp biosynthetic process GO:0006171 47 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
dna repair GO:0006281 198 0.027
muscle tissue development GO:0060537 62 0.027
epithelial cell proliferation GO:0050673 128 0.027
regulation of rna splicing GO:0043484 62 0.027
lipid modification GO:0030258 84 0.027
positive regulation of cellular component biogenesis GO:0044089 158 0.026
organelle assembly GO:0070925 176 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
response to oxygen containing compound GO:1901700 369 0.026
embryonic camera type eye development GO:0031076 2 0.026
nitrogen compound transport GO:0071705 191 0.026
hormone transport GO:0009914 68 0.026
neuron projection development GO:0031175 106 0.026
Worm Fly
epithelial to mesenchymal transition GO:0001837 48 0.026
modification by host of symbiont morphology or physiology GO:0051851 26 0.026
negative regulation of striated muscle tissue development GO:0045843 11 0.026
axonogenesis GO:0007409 31 0.026
Worm
metal ion transport GO:0030001 272 0.026
cell adhesion GO:0007155 325 0.026
skin morphogenesis GO:0043589 6 0.025
gastrulation with mouth forming second GO:0001702 1 0.025
methylation GO:0032259 106 0.025
protein processing GO:0016485 226 0.025
lymphocyte differentiation GO:0030098 35 0.025
actin cytoskeleton organization GO:0030036 207 0.025
Fly
interferon gamma production GO:0032609 39 0.025
histone lysine methylation GO:0034968 50 0.025
neural tube formation GO:0001841 3 0.025
protein targeting GO:0006605 187 0.025
negative regulation of locomotion GO:0040013 118 0.025
multicellular organismal aging GO:0010259 3 0.024
regulation of cytokine production GO:0001817 232 0.024
muscle cell proliferation GO:0033002 35 0.024
positive regulation of secretion GO:0051047 116 0.024
peptidyl lysine acetylation GO:0018394 101 0.024
regulation of phosphatase activity GO:0010921 81 0.024
cardiocyte differentiation GO:0035051 23 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.024
cellular response to lipid GO:0071396 127 0.024
positive regulation of growth GO:0045927 58 0.024
astrocyte differentiation GO:0048708 4 0.024
cell morphogenesis involved in differentiation GO:0000904 144 0.024
Worm Fly
negative regulation of immune system process GO:0002683 136 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
response to lithium ion GO:0010226 2 0.024
dna recombination GO:0006310 77 0.024
embryonic limb morphogenesis GO:0030326 9 0.024
anterior posterior axis specification GO:0009948 2 0.024
neuron fate commitment GO:0048663 2 0.023
thymus development GO:0048538 3 0.023
embryonic appendage morphogenesis GO:0035113 9 0.023
lipid localization GO:0010876 106 0.023
endosomal transport GO:0016197 129 0.023
spermatid differentiation GO:0048515 4 0.023
embryonic placenta development GO:0001892 1 0.023
reproductive system development GO:0061458 56 0.023
Worm
muscle organ development GO:0007517 56 0.023
negative regulation of cell adhesion GO:0007162 64 0.023
protein homooligomerization GO:0051260 100 0.023
negative regulation of dna binding GO:0043392 18 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
protein kinase b signaling GO:0043491 69 0.023
proteoglycan biosynthetic process GO:0030166 20 0.022
rna splicing via transesterification reactions GO:0000375 90 0.022
positive regulation of cell motility GO:2000147 177 0.022
regulation of growth GO:0040008 165 0.022
collateral sprouting GO:0048668 2 0.022
odontogenesis GO:0042476 25 0.022
cell projection morphogenesis GO:0048858 129 0.022
Worm Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
Worm
gliogenesis GO:0042063 21 0.022
ovulation cycle GO:0042698 9 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
mrna splicing via spliceosome GO:0000398 89 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
regulation of angiogenesis GO:0045765 92 0.022
forebrain development GO:0030900 26 0.022
negative regulation of growth GO:0045926 97 0.022
epithelium migration GO:0090132 119 0.022
lipid transport GO:0006869 90 0.022
t cell differentiation in thymus GO:0033077 4 0.022
negative regulation of cell death GO:0060548 345 0.021
response to oxygen levels GO:0070482 100 0.021
regulation of epithelial cell proliferation GO:0050678 113 0.021
regulation of female gonad development GO:2000194 1 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of canonical wnt signaling pathway GO:0060828 88 0.021
Human Fly
cellular response to growth factor stimulus GO:0071363 197 0.021
leukocyte activation GO:0045321 164 0.021
gtp metabolic process GO:0046039 239 0.021
negative regulation of granulocyte differentiation GO:0030853 5 0.021
blastocyst development GO:0001824 3 0.021
carbohydrate homeostasis GO:0033500 31 0.021
negative regulation of epithelial cell migration GO:0010633 38 0.021
regulation of viral transcription GO:0046782 34 0.021
actin filament based process GO:0030029 224 0.021
Fly
peptide hormone secretion GO:0030072 50 0.021
response to hypoxia GO:0001666 96 0.021
viral life cycle GO:0019058 132 0.021
development of primary sexual characteristics GO:0045137 35 0.020
Worm
reproduction GO:0000003 63 0.020
Worm
positive regulation of t cell apoptotic process GO:0070234 4 0.020
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.020
regulation of glycoprotein metabolic process GO:1903018 19 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.020
mesodermal cell differentiation GO:0048333 10 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
definitive hemopoiesis GO:0060216 2 0.020
blood vessel morphogenesis GO:0048514 162 0.020
developmental process involved in reproduction GO:0003006 66 0.020
Worm
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
cerebellum development GO:0021549 2 0.020
spinal cord development GO:0021510 4 0.020
positive regulation of mrna processing GO:0050685 17 0.020
response to starvation GO:0042594 59 0.020
cyclic nucleotide biosynthetic process GO:0009190 61 0.020
digestive tract morphogenesis GO:0048546 56 0.020
carboxylic acid catabolic process GO:0046395 71 0.019
nuclear transport GO:0051169 179 0.019
locomotory behavior GO:0007626 1 0.019
ion homeostasis GO:0050801 230 0.019
modification dependent protein catabolic process GO:0019941 209 0.019
response to uv GO:0009411 73 0.019
positive regulation of organelle organization GO:0010638 195 0.019
microtubule cytoskeleton organization GO:0000226 176 0.019
divalent inorganic cation transport GO:0072511 158 0.019
regulation of protein kinase b signaling GO:0051896 61 0.019
peptide metabolic process GO:0006518 51 0.019
chondrocyte differentiation GO:0002062 17 0.019
response to radiation GO:0009314 151 0.019
heart development GO:0007507 95 0.019
glucose homeostasis GO:0042593 31 0.019
mitotic nuclear division GO:0007067 119 0.019
histone methylation GO:0016571 60 0.019
specification of axis polarity GO:0065001 1 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
neuron death GO:0070997 65 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
negative regulation of peptidase activity GO:0010466 91 0.018
nuclear export GO:0051168 69 0.018
regulation of cell adhesion GO:0030155 166 0.018
cell activation involved in immune response GO:0002263 30 0.018
regulation of protein complex assembly GO:0043254 147 0.018
viral transcription GO:0019083 35 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.018
Human Fly
regulation of gene expression epigenetic GO:0040029 73 0.018
mammary gland morphogenesis GO:0060443 2 0.018
hair cycle process GO:0022405 12 0.018
positive regulation of protein kinase b signaling GO:0051897 42 0.018
positive regulation of t cell activation GO:0050870 54 0.018
epidermis development GO:0008544 59 0.018
response to growth factor GO:0070848 205 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
hormone mediated signaling pathway GO:0009755 22 0.018
glycoprotein biosynthetic process GO:0009101 91 0.018
myoblast fusion GO:0007520 1 0.017
t helper cell differentiation GO:0042093 4 0.017
monosaccharide metabolic process GO:0005996 74 0.017
muscle cell differentiation GO:0042692 63 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
negative regulation of kinase activity GO:0033673 106 0.017
positive regulation of ossification GO:0045778 32 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
negative regulation of transport GO:0051051 176 0.017
lung alveolus development GO:0048286 4 0.017

TLE1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.066
nervous system disease DOID:863 431 0.066
musculoskeletal system disease DOID:17 223 0.041
connective tissue disease DOID:65 109 0.041
bone disease DOID:0080001 88 0.028