Homo sapiens

89 known processes

CDC6

cell division cycle 6 homolog (S. cerevisiae)

(Aliases: HsCDC6,HsCDC18,CDC18L)

CDC6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication initiation GO:0006270 6 1.000
dna replication GO:0006260 116 0.999
mitotic cell cycle phase transition GO:0044772 162 0.978
regulation of mitosis GO:0007088 63 0.967
cell cycle g2 m phase transition GO:0044839 43 0.953
dna dependent dna replication GO:0006261 44 0.952
g1 s transition of mitotic cell cycle GO:0000082 78 0.919
cellular response to dna damage stimulus GO:0006974 379 0.903
dna repair GO:0006281 198 0.899
mitotic cell cycle GO:0000278 326 0.896
regulation of cell cycle GO:0051726 393 0.894
chromosome condensation GO:0030261 15 0.849
dna biosynthetic process GO:0071897 40 0.802
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.796
post embryonic development GO:0009791 2 0.792
Worm
positive regulation of mitotic cell cycle GO:0045931 60 0.791
regulation of cell cycle phase transition GO:1901987 126 0.777
meiosis i GO:0007127 4 0.758
sister chromatid segregation GO:0000819 54 0.725
protein dna complex subunit organization GO:0071824 80 0.713
negative regulation of cell cycle GO:0045786 193 0.695
mitotic nuclear division GO:0007067 119 0.684
regulation of gene silencing GO:0060968 24 0.654
cell cycle dna replication GO:0044786 11 0.653
mitotic cell cycle process GO:1903047 286 0.630
oocyte maturation GO:0001556 1 0.622
positive regulation of cell proliferation GO:0008284 301 0.620
chromosome segregation GO:0007059 114 0.619
negative regulation of mitotic cell cycle GO:0045930 102 0.619
dna conformation change GO:0071103 113 0.597
nuclear division GO:0000280 128 0.596
ubiquitin dependent protein catabolic process GO:0006511 206 0.586
regulation of dna replication GO:0006275 68 0.560
vesicle mediated transport GO:0016192 371 0.546
Worm
negative regulation of cell cycle process GO:0010948 121 0.527
cellular macromolecular complex assembly GO:0034622 324 0.486
Worm
nuclear dna replication GO:0033260 6 0.474
g2 m transition of mitotic cell cycle GO:0000086 41 0.458
positive regulation of cell cycle process GO:0090068 106 0.426
g2 dna damage checkpoint GO:0031572 26 0.420
exit from mitosis GO:0010458 10 0.418
protein dna complex assembly GO:0065004 64 0.415
negative regulation of cell death GO:0060548 345 0.403
regulation of meiotic cell cycle GO:0051445 4 0.401
dna packaging GO:0006323 77 0.387
double strand break repair GO:0006302 101 0.382
negative regulation of cell cycle phase transition GO:1901988 89 0.361
recombinational repair GO:0000725 50 0.349
regulation of proteasomal protein catabolic process GO:0061136 87 0.346
regulation of dna metabolic process GO:0051052 153 0.344
embryo development GO:0009790 123 0.342
Worm
mitotic dna damage checkpoint GO:0044773 28 0.341
regulation of mitotic cell cycle GO:0007346 189 0.333
purine nucleoside catabolic process GO:0006152 398 0.328
gene silencing GO:0016458 49 0.326
mitotic sister chromatid segregation GO:0000070 53 0.314
organophosphate catabolic process GO:0046434 430 0.305
double strand break repair via homologous recombination GO:0000724 50 0.297
negative regulation of programmed cell death GO:0043069 321 0.297
determination of adult lifespan GO:0008340 2 0.283
organelle fission GO:0048285 149 0.282
positive regulation of meiotic cell cycle GO:0051446 2 0.260
cell cycle arrest GO:0007050 71 0.259
positive regulation of developmental process GO:0051094 314 0.257
dna recombination GO:0006310 77 0.240
growth GO:0040007 202 0.234
regulation of growth GO:0040008 165 0.224
nervous system development GO:0007399 293 0.222
nucleoside phosphate catabolic process GO:1901292 412 0.216
positive regulation of multicellular organism growth GO:0040018 6 0.211
protein ubiquitination GO:0016567 314 0.208
cell cycle g1 s phase transition GO:0044843 80 0.205
female gamete generation GO:0007292 2 0.184
chromatin silencing GO:0006342 12 0.176
purine nucleotide catabolic process GO:0006195 405 0.175
meiotic chromosome segregation GO:0045132 4 0.173
regulation of g0 to g1 transition GO:0070316 2 0.167
negative regulation of mitosis GO:0045839 24 0.166
cellular amine metabolic process GO:0044106 41 0.165
microtubule cytoskeleton organization GO:0000226 176 0.162
negative regulation of apoptotic process GO:0043066 316 0.162
cell aging GO:0007569 52 0.161
microtubule based process GO:0007017 210 0.160
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.156
response to abiotic stimulus GO:0009628 336 0.150
protein modification by small protein conjugation GO:0032446 342 0.150
positive regulation of cell cycle GO:0045787 140 0.148
neurogenesis GO:0022008 169 0.145
negative regulation of cellular catabolic process GO:0031330 83 0.145
cellular macromolecule catabolic process GO:0044265 380 0.145
regulation of dna dependent dna replication initiation GO:0030174 3 0.139
cell cell signaling involved in cell fate commitment GO:0045168 5 0.134
mitotic dna integrity checkpoint GO:0044774 30 0.133
cell cycle checkpoint GO:0000075 117 0.131
cellular protein catabolic process GO:0044257 261 0.131
purine nucleoside triphosphate metabolic process GO:0009144 412 0.128
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.128
positive regulation of dna metabolic process GO:0051054 73 0.126
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.125
mitotic g2 dna damage checkpoint GO:0007095 7 0.123
response to other organism GO:0051707 261 0.123
small gtpase mediated signal transduction GO:0007264 78 0.123
positive regulation of cell cycle g2 m phase transition GO:1902751 8 0.117
modification dependent macromolecule catabolic process GO:0043632 212 0.117
regulation of cell cycle process GO:0010564 266 0.116
negative regulation of phosphate metabolic process GO:0045936 267 0.116
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.115
cell fate determination GO:0001709 3 0.111
sex differentiation GO:0007548 45 0.110
Worm
cell cycle phase transition GO:0044770 173 0.109
chromatin organization GO:0006325 351 0.106
cell development GO:0048468 328 0.105
Worm
organophosphate biosynthetic process GO:0090407 163 0.101
protein catabolic process GO:0030163 325 0.097
positive regulation of apoptotic process GO:0043065 246 0.096
positive regulation of dna replication GO:0045740 35 0.096
regulation of kinase activity GO:0043549 314 0.094
peptidyl serine phosphorylation GO:0018105 101 0.092
regulation of gene expression epigenetic GO:0040029 73 0.091
development of primary sexual characteristics GO:0045137 35 0.089
Worm
regulation of response to dna damage stimulus GO:2001020 94 0.089
nucleoside catabolic process GO:0009164 408 0.088
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.083
positive regulation of programmed cell death GO:0043068 249 0.083
positive regulation of cell division GO:0051781 59 0.082
cell fate commitment GO:0045165 27 0.082
regulation of nucleotide catabolic process GO:0030811 205 0.082
ribonucleoside triphosphate metabolic process GO:0009199 412 0.079
atp catabolic process GO:0006200 157 0.078
reproductive system development GO:0061458 56 0.078
Worm
positive regulation of organelle organization GO:0010638 195 0.077
negative regulation of catalytic activity GO:0043086 335 0.076
negative regulation of meiotic cell cycle GO:0051447 2 0.075
response to metal ion GO:0010038 84 0.074
negative regulation of gene expression epigenetic GO:0045814 19 0.073
reproductive process GO:0022414 106 0.073
Worm
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.073
microtubule organizing center organization GO:0031023 62 0.071
developmental process involved in reproduction GO:0003006 66 0.071
Worm
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.066
regulation of protein serine threonine kinase activity GO:0071900 179 0.065
cell type specific apoptotic process GO:0097285 125 0.064
mitotic cell cycle checkpoint GO:0007093 68 0.064
positive regulation of catabolic process GO:0009896 310 0.061
meiotic cell cycle GO:0051321 13 0.060
centrosome organization GO:0051297 58 0.060
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.058
nucleotide catabolic process GO:0009166 408 0.056
regulation of purine nucleotide metabolic process GO:1900542 264 0.056
cell division GO:0051301 168 0.054
gonad development GO:0008406 34 0.054
Worm
regulation of protein ubiquitination GO:0031396 95 0.053
reproductive structure development GO:0048608 55 0.053
Worm
regulation of exit from mitosis GO:0007096 6 0.053
gtp catabolic process GO:0006184 237 0.053
cytokinesis GO:0000910 96 0.053
positive regulation of cell death GO:0010942 263 0.052
nucleoside triphosphate catabolic process GO:0009143 394 0.051
regulation of mitotic cell cycle phase transition GO:1901990 118 0.050
apoptotic signaling pathway GO:0097190 268 0.050
response to fungus GO:0009620 4 0.049
purine ribonucleoside catabolic process GO:0046130 398 0.049
ribonucleoside monophosphate metabolic process GO:0009161 187 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
regulation of chromosome segregation GO:0051983 44 0.048
chromatin modification GO:0016568 298 0.048
negative regulation of protein maturation GO:1903318 142 0.048
nucleoside triphosphate metabolic process GO:0009141 422 0.048
positive regulation of gtp catabolic process GO:0033126 166 0.048
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.048
cellular amino acid metabolic process GO:0006520 116 0.046
autophagic cell death GO:0048102 3 0.046
positive regulation of cytoskeleton organization GO:0051495 83 0.045
dna integrity checkpoint GO:0031570 71 0.045
negative regulation of transferase activity GO:0051348 124 0.044
oogenesis GO:0048477 2 0.044
chromosome separation GO:0051304 23 0.044
hematopoietic or lymphoid organ development GO:0048534 186 0.044
spindle stabilization GO:0043146 4 0.044
reproduction GO:0000003 63 0.044
Worm
positive regulation of cellular catabolic process GO:0031331 284 0.043
multicellular organismal aging GO:0010259 3 0.042
response to external biotic stimulus GO:0043207 261 0.042
regulation of transferase activity GO:0051338 355 0.042
synaptic transmission involved in micturition GO:0060084 2 0.041
chromatin remodeling GO:0006338 55 0.041
regulation of proteolysis GO:0030162 293 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
regulation of developmental growth GO:0048638 30 0.040
regulation of protein kinase activity GO:0045859 289 0.039
response to decreased oxygen levels GO:0036293 96 0.039
response to ionizing radiation GO:0010212 65 0.039
cell cell signaling GO:0007267 155 0.039
oocyte differentiation GO:0009994 2 0.039
endocytosis GO:0006897 159 0.038
Worm
humoral immune response GO:0006959 49 0.038
purine containing compound catabolic process GO:0072523 411 0.037
cellular response to decreased oxygen levels GO:0036294 51 0.037
meiotic nuclear division GO:0007126 10 0.036
dna strand elongation involved in dna replication GO:0006271 3 0.036
response to radiation GO:0009314 151 0.036
negative regulation of organelle organization GO:0010639 126 0.036
ras protein signal transduction GO:0007265 73 0.036
generation of neurons GO:0048699 152 0.035
positive regulation of cell cycle phase transition GO:1901989 22 0.034
cellular response to iron ion GO:0071281 1 0.034
regulation of nucleoside metabolic process GO:0009118 209 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.033
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
regulation of protein maturation GO:1903317 150 0.032
negative regulation of protein modification process GO:0031400 200 0.031
cellular response to oxygen levels GO:0071453 55 0.031
regulation of cell cycle g1 s phase transition GO:1902806 42 0.031
regulation of cell division GO:0051302 116 0.031
single organism reproductive process GO:0044702 98 0.030
Worm
eye development GO:0001654 42 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
positive regulation of nuclear cell cycle dna replication GO:0010571 4 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
ribonucleoside catabolic process GO:0042454 406 0.029
negative regulation of proteolysis GO:0045861 132 0.029
developmental growth GO:0048589 48 0.029
positive regulation of protein kinase activity GO:0045860 190 0.028
regeneration GO:0031099 4 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.027
modification dependent protein catabolic process GO:0019941 209 0.027
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.026
engulfment of apoptotic cell GO:0043652 2 0.026
attachment of spindle microtubules to kinetochore GO:0008608 17 0.026
regulation of dna dependent dna replication GO:0090329 19 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.026
response to biotic stimulus GO:0009607 276 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
response to light stimulus GO:0009416 87 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
oocyte development GO:0048599 1 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.025
regulation of protein processing GO:0070613 150 0.024
dna catabolic process GO:0006308 49 0.024
negative regulation of catabolic process GO:0009895 104 0.024
dna damage checkpoint GO:0000077 68 0.024
multicellular organism reproduction GO:0032504 42 0.023
cellular component assembly involved in morphogenesis GO:0010927 73 0.023
Worm
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.023
negative regulation of cellular protein catabolic process GO:1903363 38 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
urogenital system development GO:0001655 65 0.023
cellular ketone metabolic process GO:0042180 80 0.023
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.023
response to inorganic substance GO:0010035 127 0.023
glycosyl compound catabolic process GO:1901658 413 0.022
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
sensory organ development GO:0007423 52 0.022
gtp metabolic process GO:0046039 239 0.022
negative regulation of sister chromatid segregation GO:0033046 17 0.022
cell projection organization GO:0030030 252 0.022
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
regulation of binding GO:0051098 111 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
negative regulation of cell division GO:0051782 31 0.021
cellular response to hypoxia GO:0071456 51 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
regulation of meiosis GO:0040020 3 0.020
centrosome cycle GO:0007098 32 0.020
regulation of mapk cascade GO:0043408 262 0.020
cellular component disassembly GO:0022411 92 0.020
g0 to g1 transition GO:0045023 3 0.020
positive regulation of growth GO:0045927 58 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
regulation of protein catabolic process GO:0042176 155 0.019
muscle cell proliferation GO:0033002 35 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
negative regulation of protein processing GO:0010955 142 0.019
mitotic g2 m transition checkpoint GO:0044818 9 0.019
signal transduction in response to dna damage GO:0042770 57 0.019
neuron differentiation GO:0030182 138 0.019
triglyceride catabolic process GO:0019433 10 0.019
positive regulation of meiosis GO:0045836 2 0.019
cell adhesion GO:0007155 325 0.018
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.018
small molecule biosynthetic process GO:0044283 157 0.018
regulation of mitotic sister chromatid separation GO:0010965 27 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
Worm
organelle assembly GO:0070925 176 0.018
Worm
cellular lipid metabolic process GO:0044255 303 0.018
regulation of smooth muscle cell proliferation GO:0048660 28 0.017
peptidyl serine modification GO:0018209 106 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
alpha amino acid metabolic process GO:1901605 72 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
regulation of cell differentiation GO:0045595 393 0.017
cell growth GO:0016049 160 0.017
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.016
regulation of microtubule cytoskeleton organization GO:0070507 61 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
regulation of multicellular organism growth GO:0040014 8 0.016
positive regulation of fibroblast proliferation GO:0048146 21 0.016
regulation of cellular response to stress GO:0080135 244 0.016
regulation of gtpase activity GO:0043087 180 0.016
biological adhesion GO:0022610 331 0.016
secretion GO:0046903 254 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of microtubule based process GO:0032886 74 0.015
organelle localization GO:0051640 84 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
sister chromatid cohesion GO:0007062 24 0.015
7 methylguanosine mrna capping GO:0006370 7 0.015
aging GO:0007568 66 0.015
mitotic sister chromatid separation GO:0051306 18 0.015
cellular protein complex assembly GO:0043623 188 0.015
Worm
regulation of dna repair GO:0006282 47 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
cellular response to inorganic substance GO:0071241 45 0.015
protein processing GO:0016485 226 0.014
multicellular organismal reproductive process GO:0048609 40 0.014
stem cell differentiation GO:0048863 93 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.014
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.014
negative regulation of cell proliferation GO:0008285 228 0.013
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.013
coenzyme metabolic process GO:0006732 65 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
dephosphorylation GO:0016311 209 0.013
cofactor metabolic process GO:0051186 87 0.013
telomere maintenance GO:0000723 32 0.013
spindle organization GO:0007051 53 0.013
negative regulation of cytoskeleton organization GO:0051494 45 0.013
response to oxygen levels GO:0070482 100 0.013
regulation of ubiquitin protein transferase activity GO:0051438 28 0.013
cellular lipid catabolic process GO:0044242 65 0.012
membrane organization GO:0061024 292 0.012
protein complex localization GO:0031503 31 0.012
neuron development GO:0048666 113 0.012
jak stat cascade GO:0007259 46 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
centrosome duplication GO:0051298 28 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of chromatin silencing GO:0031935 8 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
dna endoreduplication GO:0042023 5 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
protein complex disassembly GO:0043241 52 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
body morphogenesis GO:0010171 11 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
response to purine containing compound GO:0014074 40 0.011
mitotic spindle organization GO:0007052 27 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
organ morphogenesis GO:0009887 147 0.011
circulatory system development GO:0072359 262 0.011
cellular component morphogenesis GO:0032989 314 0.011
Worm
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.011
protein alkylation GO:0008213 74 0.011
lagging strand elongation GO:0006273 3 0.010
glycerolipid catabolic process GO:0046503 18 0.010
epithelial cell differentiation GO:0030855 141 0.010
cardiovascular system development GO:0072358 262 0.010
mature ribosome assembly GO:0042256 5 0.010
covalent chromatin modification GO:0016569 254 0.010

CDC6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.081
carbohydrate metabolic disorder DOID:2978 55 0.081
inherited metabolic disorder DOID:655 242 0.081