Homo sapiens

0 known processes

NKX6-3

NK6 homeobox 3

(Aliases: FLJ25169,NKX6.3)

NKX6-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 399 0.152
cation transport GO:0006812 331 0.111
cation transmembrane transport GO:0098655 238 0.076
post embryonic development GO:0009791 2 0.071
regulation of cellular ketone metabolic process GO:0010565 50 0.063
cellular amino acid metabolic process GO:0006520 116 0.061
ion transmembrane transport GO:0034220 338 0.054
system process GO:0003008 349 0.054
cellular component morphogenesis GO:0032989 314 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
metal ion transport GO:0030001 272 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.049
cellular amine metabolic process GO:0044106 41 0.048
actin filament based movement GO:0030048 17 0.046
positive regulation of cellular amine metabolic process GO:0033240 7 0.046
cellular ion homeostasis GO:0006873 168 0.044
positive regulation of cellular component organization GO:0051130 376 0.043
potassium ion transmembrane transport GO:0071805 60 0.043
lipid metabolic process GO:0006629 381 0.042
cell projection organization GO:0030030 252 0.042
multicellular organismal aging GO:0010259 3 0.041
inorganic cation transmembrane transport GO:0098662 194 0.041
actin filament based process GO:0030029 224 0.040
determination of adult lifespan GO:0008340 2 0.039
regulation of cell cycle GO:0051726 393 0.039
positive regulation of transport GO:0051050 336 0.038
female gamete generation GO:0007292 2 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.036
cytoplasmic transport GO:0016482 379 0.036
amine metabolic process GO:0009308 44 0.034
cell morphogenesis GO:0000902 296 0.034
cellular homeostasis GO:0019725 196 0.034
organ morphogenesis GO:0009887 147 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
epidermis morphogenesis GO:0048730 3 0.033
cellular response to dna damage stimulus GO:0006974 379 0.033
nervous system development GO:0007399 293 0.032
ras protein signal transduction GO:0007265 73 0.032
cardiac muscle cell contraction GO:0086003 4 0.032
inorganic ion transmembrane transport GO:0098660 231 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
cellular ketone metabolic process GO:0042180 80 0.032
oogenesis GO:0048477 2 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
micturition GO:0060073 3 0.031
hindbrain development GO:0030902 3 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
single organism cellular localization GO:1902580 332 0.030
nucleotide catabolic process GO:0009166 408 0.029
positive regulation of phosphorylation GO:0042327 394 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.028
response to abiotic stimulus GO:0009628 336 0.028
segmentation GO:0035282 4 0.028
locomotory behavior GO:0007626 1 0.028
glycosyl compound catabolic process GO:1901658 413 0.028
positive regulation of catabolic process GO:0009896 310 0.028
embryonic camera type eye development GO:0031076 2 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
monovalent inorganic cation transport GO:0015672 128 0.026
cell development GO:0048468 328 0.026
actin mediated cell contraction GO:0070252 12 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
cell part morphogenesis GO:0032990 137 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
nucleoside catabolic process GO:0009164 408 0.025
positive regulation of developmental process GO:0051094 314 0.025
cellular cation homeostasis GO:0030003 163 0.025
secretion GO:0046903 254 0.025
epithelium development GO:0060429 227 0.025
Mouse
chromatin modification GO:0016568 298 0.025
single organism membrane organization GO:0044802 268 0.024
protein oligomerization GO:0051259 173 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
regulation of protein localization GO:0032880 296 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
chromatin organization GO:0006325 351 0.024
mapk cascade GO:0000165 288 0.024
organophosphate catabolic process GO:0046434 430 0.024
regulation of cell motility GO:2000145 299 0.024
response to oxygen containing compound GO:1901700 369 0.024
cell activation GO:0001775 213 0.024
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.024
purine containing compound catabolic process GO:0072523 411 0.024
regeneration GO:0031099 4 0.023
membrane organization GO:0061024 292 0.023
cellular response to endogenous stimulus GO:0071495 336 0.023
positive regulation of transferase activity GO:0051347 227 0.023
regulation of cellular response to stress GO:0080135 244 0.023
regulation of transferase activity GO:0051338 355 0.023
regulation of transmembrane transport GO:0034762 139 0.023
chemical homeostasis GO:0048878 306 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
protein ubiquitination GO:0016567 314 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
organelle assembly GO:0070925 176 0.022
regulation of kinase activity GO:0043549 314 0.022
action potential GO:0001508 34 0.022
mating GO:0007618 1 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
response to biotic stimulus GO:0009607 276 0.022
mitotic cell cycle GO:0000278 326 0.022
cellular calcium ion homeostasis GO:0006874 117 0.022
anatomical structure homeostasis GO:0060249 100 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
positive regulation of hydrolase activity GO:0051345 331 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
neuromuscular junction development GO:0007528 3 0.021
negative regulation of cell death GO:0060548 345 0.021
regulation of membrane potential GO:0042391 95 0.021
ion homeostasis GO:0050801 230 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
regulation of ion transport GO:0043269 189 0.021
regulation of cell cycle process GO:0010564 266 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
negative regulation of catalytic activity GO:0043086 335 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
defense response GO:0006952 315 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
calcium ion homeostasis GO:0055074 122 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
biological adhesion GO:0022610 331 0.020
dephosphorylation GO:0016311 209 0.020
dna repair GO:0006281 198 0.020
cell cell signaling GO:0007267 155 0.020
protein localization to membrane GO:0072657 160 0.020
cellular lipid metabolic process GO:0044255 303 0.020
cardiovascular system development GO:0072358 262 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
protein localization to organelle GO:0033365 280 0.020
innate immune response GO:0045087 178 0.019
regulation of cellular component movement GO:0051270 334 0.019
protein catabolic process GO:0030163 325 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
regulation of protein transport GO:0051223 213 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
small molecule biosynthetic process GO:0044283 157 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
cellular chemical homeostasis GO:0055082 180 0.019
regulation of protein kinase activity GO:0045859 289 0.019
endomembrane system organization GO:0010256 196 0.019
circulatory system development GO:0072359 262 0.019
taxis GO:0042330 157 0.019
growth GO:0040007 202 0.018
histone modification GO:0016570 251 0.018
mitotic cell cycle process GO:1903047 286 0.018
intracellular protein transport GO:0006886 270 0.018
cation homeostasis GO:0055080 189 0.018
striated muscle contraction GO:0006941 52 0.018
immune response GO:0006955 307 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
regulation of cell differentiation GO:0045595 393 0.018
Mouse
epithelial cell differentiation GO:0030855 141 0.018
Mouse
divalent inorganic cation homeostasis GO:0072507 136 0.018
actin cytoskeleton organization GO:0030036 207 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
potassium ion transport GO:0006813 62 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
response to external biotic stimulus GO:0043207 261 0.017
cell morphogenesis involved in differentiation GO:0000904 144 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
adult locomotory behavior GO:0008344 1 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
lung alveolus development GO:0048286 4 0.017
response to nitrogen compound GO:1901698 184 0.017
metal ion homeostasis GO:0055065 169 0.017
cell projection morphogenesis GO:0048858 129 0.017
associative learning GO:0008306 1 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
anterior posterior axis specification GO:0009948 2 0.017
vesicle mediated transport GO:0016192 371 0.017
protein maturation GO:0051604 233 0.017
cell adhesion GO:0007155 325 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
cardiac muscle contraction GO:0060048 34 0.017
regulation of mapk cascade GO:0043408 262 0.017
cell cycle phase transition GO:0044770 173 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
keratinization GO:0031424 2 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
positive regulation of kinase activity GO:0033674 204 0.016
organ formation GO:0048645 3 0.016
central nervous system development GO:0007417 123 0.016
head development GO:0060322 108 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
regulation of locomotion GO:0040012 329 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
positive regulation of organelle organization GO:0010638 195 0.016
negative regulation of protein modification process GO:0031400 200 0.016
positive regulation of protein transport GO:0051222 135 0.016
maintenance of location GO:0051235 112 0.016
covalent chromatin modification GO:0016569 254 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
atp metabolic process GO:0046034 176 0.015
neurogenesis GO:0022008 169 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
neurological system process GO:0050877 163 0.015
rhythmic behavior GO:0007622 2 0.015
divalent inorganic cation transport GO:0072511 158 0.015
cellular protein catabolic process GO:0044257 261 0.015
oxidation reduction process GO:0055114 396 0.015
embryonic eye morphogenesis GO:0048048 2 0.015
protein targeting GO:0006605 187 0.015
positive regulation of ion transport GO:0043270 87 0.015
copulation GO:0007620 1 0.015
nitrogen compound transport GO:0071705 191 0.015
regulation of protein complex assembly GO:0043254 147 0.015
muscle contraction GO:0006936 73 0.015
chemotaxis GO:0006935 157 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
metencephalon development GO:0022037 2 0.015
cerebellum development GO:0021549 2 0.015
immune system development GO:0002520 195 0.015
nuclear transport GO:0051169 179 0.015
cardiac ventricle formation GO:0003211 2 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
cytokine production GO:0001816 247 0.015
blastoderm segmentation GO:0007350 2 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
rho protein signal transduction GO:0007266 26 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of ion transmembrane transport GO:0034765 132 0.015
leukocyte activation GO:0045321 164 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
hemopoiesis GO:0030097 180 0.015
oocyte differentiation GO:0009994 2 0.015
tissue regeneration GO:0042246 3 0.014
ameboidal type cell migration GO:0001667 135 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
microtubule based process GO:0007017 210 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
blastocyst development GO:0001824 3 0.014
regulation of cell development GO:0060284 161 0.014
hair follicle morphogenesis GO:0031069 2 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
positive regulation of immune system process GO:0002684 283 0.014
apoptotic signaling pathway GO:0097190 268 0.014
response to radiation GO:0009314 151 0.014
positive regulation of cell motility GO:2000147 177 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
wnt signaling pathway GO:0016055 156 0.014
positive regulation of cell cycle GO:0045787 140 0.014
regulation of intracellular transport GO:0032386 195 0.014
plasma membrane organization GO:0007009 115 0.014
alpha ketoglutarate transport GO:0015742 1 0.014
alcohol metabolic process GO:0006066 114 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
memory GO:0007613 3 0.014
regulation of actin filament based process GO:0032970 141 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of secretion GO:0051046 194 0.014
oocyte development GO:0048599 1 0.013
glycoprotein metabolic process GO:0009100 110 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
blood vessel development GO:0001568 172 0.013
cell projection assembly GO:0030031 126 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
cell division GO:0051301 168 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
neuron differentiation GO:0030182 138 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
atp catabolic process GO:0006200 157 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
neuroblast proliferation GO:0007405 4 0.013
regulation of homeostatic process GO:0032844 121 0.013
regulation of growth GO:0040008 165 0.013
post embryonic organ development GO:0048569 1 0.013
interspecies interaction between organisms GO:0044419 156 0.013
brain development GO:0007420 97 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
generation of neurons GO:0048699 152 0.013
spinal cord development GO:0021510 4 0.013
sequestering of calcium ion GO:0051208 17 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
optic nerve development GO:0021554 2 0.013
regulation of dna metabolic process GO:0051052 153 0.013
protein processing GO:0016485 226 0.013
secretion by cell GO:0032940 226 0.012
pituitary gland development GO:0021983 2 0.012
muscle system process GO:0003012 81 0.012
divalent metal ion transport GO:0070838 152 0.012
spermatid development GO:0007286 4 0.012
response to growth factor GO:0070848 205 0.012
sequestering of metal ion GO:0051238 24 0.012
multi organism cellular process GO:0044764 156 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
multicellular organismal signaling GO:0035637 34 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
regulation of metal ion transport GO:0010959 120 0.012
positive regulation of cell division GO:0051781 59 0.012
organic hydroxy compound transport GO:0015850 63 0.012
peripheral nervous system development GO:0007422 2 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
response to wounding GO:0009611 168 0.012
reproductive process GO:0022414 106 0.012
Worm
protein localization to plasma membrane GO:0072659 93 0.012
protein autophosphorylation GO:0046777 123 0.012
regulation of cell projection organization GO:0031344 107 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
regulation of hormone levels GO:0010817 125 0.012
cell growth GO:0016049 160 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
rna processing GO:0006396 255 0.012
calcium ion transport GO:0006816 147 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
embryonic camera type eye formation GO:0060900 2 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
carbohydrate metabolic process GO:0005975 207 0.012
positive regulation of cell migration GO:0030335 172 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
aortic valve development GO:0003176 3 0.012
anion transport GO:0006820 161 0.012
response to organonitrogen compound GO:0010243 156 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.011
circulatory system process GO:0003013 113 0.011
positive regulation of cytokine production GO:0001819 167 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
cellular potassium ion transport GO:0071804 60 0.011
circadian behavior GO:0048512 2 0.011
cellular protein complex assembly GO:0043623 188 0.011
muscle tissue development GO:0060537 62 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of transporter activity GO:0032409 82 0.011
regulation of ion homeostasis GO:2000021 73 0.011
response to organic cyclic compound GO:0014070 204 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
sex determination GO:0007530 3 0.011
stress activated mapk cascade GO:0051403 93 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of proteolysis GO:0030162 293 0.011
tube development GO:0035295 125 0.011
visual behavior GO:0007632 2 0.011
convergent extension GO:0060026 1 0.011
lipid biosynthetic process GO:0008610 177 0.011
positive regulation of secretion GO:0051047 116 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
regulation of cytokine production GO:0001817 232 0.011
neuron development GO:0048666 113 0.011
regulation of anatomical structure size GO:0090066 101 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
cell fate determination GO:0001709 3 0.011
Mouse
inner ear morphogenesis GO:0042472 4 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
establishment of protein localization to plasma membrane GO:0090002 68 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
somitogenesis GO:0001756 2 0.011
response to other organism GO:0051707 261 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
muscle cell cellular homeostasis GO:0046716 3 0.011
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
regulation of cytoskeleton organization GO:0051493 177 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
organic anion transport GO:0015711 103 0.010
regulation of cell division GO:0051302 116 0.010
canonical wnt signaling pathway GO:0060070 116 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
endocytosis GO:0006897 159 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
blood circulation GO:0008015 113 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
tripartite regional subdivision GO:0007351 2 0.010
detection of stimulus GO:0051606 85 0.010
cardiac chamber formation GO:0003207 2 0.010
regulation of binding GO:0051098 111 0.010
compound eye development GO:0048749 1 0.010
response to inorganic substance GO:0010035 127 0.010
muscle structure development GO:0061061 98 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
regulation of striated muscle contraction GO:0006942 37 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
regulation of cell migration GO:0030334 289 0.010
nuclear import GO:0051170 106 0.010
signal release GO:0023061 70 0.010

NKX6-3 disease predictions

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 118 0.057
night blindness DOID:8499 10 0.057
sensory system disease DOID:0050155 203 0.057
eye and adnexa disease DOID:1492 150 0.057
nervous system disease DOID:863 431 0.057
eye disease DOID:5614 149 0.057
congenital stationary night blindness DOID:0050534 8 0.034
musculoskeletal system disease DOID:17 223 0.029
retinal degeneration DOID:8466 89 0.021
disease of metabolism DOID:0014667 295 0.019
cardiovascular system disease DOID:1287 106 0.012
inherited metabolic disorder DOID:655 242 0.012
central nervous system disease DOID:331 186 0.012
bone disease DOID:0080001 88 0.011
connective tissue disease DOID:65 109 0.011