Homo sapiens

0 known processes

KIAA2026

KIAA2026

KIAA2026 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.117
memory GO:0007613 3 0.113
regulation of cell differentiation GO:0045595 393 0.102
lung saccule development GO:0060430 2 0.100
nervous system development GO:0007399 293 0.088
cell development GO:0048468 328 0.085
cellular component morphogenesis GO:0032989 314 0.077
lung alveolus development GO:0048286 4 0.077
positive regulation of developmental process GO:0051094 314 0.071
negative regulation of cell death GO:0060548 345 0.067
covalent chromatin modification GO:0016569 254 0.063
cellular macromolecular complex assembly GO:0034622 324 0.062
lipid biosynthetic process GO:0008610 177 0.059
neurological system process GO:0050877 163 0.058
forebrain dorsal ventral pattern formation GO:0021798 1 0.057
positive regulation of cellular component organization GO:0051130 376 0.054
pituitary gland development GO:0021983 2 0.050
cellular response to dna damage stimulus GO:0006974 379 0.050
cell projection organization GO:0030030 252 0.046
determination of adult lifespan GO:0008340 2 0.045
cytoplasmic transport GO:0016482 379 0.045
neuromuscular junction development GO:0007528 3 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
system process GO:0003008 349 0.043
cell morphogenesis GO:0000902 296 0.043
secretion GO:0046903 254 0.043
tube development GO:0035295 125 0.043
compound eye development GO:0048749 1 0.043
generation of neurons GO:0048699 152 0.042
multicellular organismal aging GO:0010259 3 0.042
myeloid cell differentiation GO:0030099 117 0.042
actin filament based process GO:0030029 224 0.042
amine metabolic process GO:0009308 44 0.042
positive regulation of catabolic process GO:0009896 310 0.040
gtp metabolic process GO:0046039 239 0.039
lipid metabolic process GO:0006629 381 0.038
negative regulation of cell proliferation GO:0008285 228 0.038
somatic stem cell maintenance GO:0035019 4 0.036
positive regulation of cell differentiation GO:0045597 211 0.035
tissue morphogenesis GO:0048729 96 0.035
nuclear transport GO:0051169 179 0.035
metal ion transport GO:0030001 272 0.035
central nervous system development GO:0007417 123 0.035
post embryonic development GO:0009791 2 0.035
positive regulation of transport GO:0051050 336 0.034
negative regulation of apoptotic process GO:0043066 316 0.034
histone modification GO:0016570 251 0.033
regulation of proteolysis GO:0030162 293 0.033
negative regulation of transport GO:0051051 176 0.032
cellular amino acid metabolic process GO:0006520 116 0.032
cell fate determination GO:0001709 3 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
female gamete generation GO:0007292 2 0.031
oogenesis GO:0048477 2 0.031
nucleotide catabolic process GO:0009166 408 0.031
response to organonitrogen compound GO:0010243 156 0.031
epithelium development GO:0060429 227 0.031
interspecies interaction between organisms GO:0044419 156 0.031
regulation of cell cycle GO:0051726 393 0.030
viral life cycle GO:0019058 132 0.029
regulation of secretion GO:0051046 194 0.029
response to glucagon GO:0033762 1 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
organelle assembly GO:0070925 176 0.028
chromatin modification GO:0016568 298 0.028
nitrogen compound transport GO:0071705 191 0.028
tube morphogenesis GO:0035239 95 0.027
membrane organization GO:0061024 292 0.027
regulation of secretion by cell GO:1903530 177 0.027
endomembrane system organization GO:0010256 196 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
protein autophosphorylation GO:0046777 123 0.026
secretion by cell GO:0032940 226 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
multi organism cellular process GO:0044764 156 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
single organism membrane organization GO:0044802 268 0.025
neuron differentiation GO:0030182 138 0.025
vesicle mediated transport GO:0016192 371 0.025
neuron projection development GO:0031175 106 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
regulation of cell development GO:0060284 161 0.025
methylation GO:0032259 106 0.025
peptidyl lysine modification GO:0018205 144 0.025
renal sodium ion absorption GO:0070294 2 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
circulatory system development GO:0072359 262 0.024
midgut development GO:0007494 1 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
glial cell migration GO:0008347 4 0.024
cellular response to oxygen containing compound GO:1901701 276 0.024
positive regulation of dendrite morphogenesis GO:0050775 3 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.023
associative learning GO:0008306 1 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
primary neural tube formation GO:0014020 3 0.023
regulation of cell cycle process GO:0010564 266 0.022
neurogenesis GO:0022008 169 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
brain development GO:0007420 97 0.022
cation transport GO:0006812 331 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
cellular protein complex assembly GO:0043623 188 0.022
kidney development GO:0001822 53 0.022
muscle structure development GO:0061061 98 0.021
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
regulation of hormone secretion GO:0046883 57 0.021
response to nitrogen compound GO:1901698 184 0.021
growth GO:0040007 202 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
regulation of protein localization GO:0032880 296 0.021
long term memory GO:0007616 2 0.021
response to external biotic stimulus GO:0043207 261 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
regulation of hormone levels GO:0010817 125 0.020
response to oxygen containing compound GO:1901700 369 0.020
metencephalon development GO:0022037 2 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
muscle cell fate commitment GO:0042693 4 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
protein methylation GO:0006479 74 0.020
lung epithelial cell differentiation GO:0060487 1 0.020
regulation of protein transport GO:0051223 213 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
hemopoiesis GO:0030097 180 0.020
hormone secretion GO:0046879 65 0.020
positive regulation of ossification GO:0045778 32 0.020
head development GO:0060322 108 0.019
mesodermal cell fate specification GO:0007501 2 0.019
biological adhesion GO:0022610 331 0.019
lung cell differentiation GO:0060479 1 0.019
regulation of protein complex assembly GO:0043254 147 0.019
nuclear import GO:0051170 106 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
mitotic cell cycle GO:0000278 326 0.019
secretory granule organization GO:0033363 2 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
mitotic cell cycle process GO:1903047 286 0.019
cellular ketone metabolic process GO:0042180 80 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
regulation of myeloid cell differentiation GO:0045637 81 0.018
neural crest cell development GO:0014032 3 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
nucleoside catabolic process GO:0009164 408 0.018
regulation of gtpase activity GO:0043087 180 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
blastoderm segmentation GO:0007350 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
histone acetylation GO:0016573 93 0.018
regulation of intracellular transport GO:0032386 195 0.018
actin cytoskeleton organization GO:0030036 207 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
limbic system development GO:0021761 3 0.017
organophosphate catabolic process GO:0046434 430 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
cell projection morphogenesis GO:0048858 129 0.017
cytokine production GO:0001816 247 0.017
cell part morphogenesis GO:0032990 137 0.017
regulation of cell division GO:0051302 116 0.017
peptidyl lysine acetylation GO:0018394 101 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
chromatin organization GO:0006325 351 0.017
endosomal transport GO:0016197 129 0.017
regulation of actin filament based process GO:0032970 141 0.017
transmembrane transport GO:0055085 399 0.016
protein alkylation GO:0008213 74 0.016
viral process GO:0016032 146 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
protein k33 linked ubiquitination GO:1990390 1 0.016
dephosphorylation GO:0016311 209 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
phospholipid metabolic process GO:0006644 99 0.016
positive regulation of proteolysis GO:0045862 142 0.016
actin filament organization GO:0007015 128 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
positive regulation of cell migration GO:0030335 172 0.015
stem cell differentiation GO:0048863 93 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
spermatid differentiation GO:0048515 4 0.015
cellular amine metabolic process GO:0044106 41 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
digestive tract development GO:0048565 75 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
regulation of protein catabolic process GO:0042176 155 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
chemical homeostasis GO:0048878 306 0.015
cytokinesis GO:0000910 96 0.015
regulation of cellular response to stress GO:0080135 244 0.015
response to other organism GO:0051707 261 0.015
protein ubiquitination GO:0016567 314 0.015
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
visual behavior GO:0007632 2 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
regulation of growth GO:0040008 165 0.014
regulation of ossification GO:0030278 58 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
single organism cellular localization GO:1902580 332 0.014
positive regulation of protein complex assembly GO:0031334 86 0.014
signal release GO:0023061 70 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
behavior GO:0007610 112 0.014
myosin filament organization GO:0031033 2 0.013
immune system development GO:0002520 195 0.013
protein stabilization GO:0050821 64 0.013
amide transport GO:0042886 76 0.013
histone methylation GO:0016571 60 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
regulation of response to external stimulus GO:0032101 222 0.013
embryonic placenta development GO:0001892 1 0.013
nuclear export GO:0051168 69 0.013
response to cytokine GO:0034097 232 0.013
embryonic viscerocranium morphogenesis GO:0048703 1 0.013
ras protein signal transduction GO:0007265 73 0.013
maintenance of location GO:0051235 112 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
regulation of body fluid levels GO:0050878 99 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
regulation of peptide transport GO:0090087 62 0.013
macromolecule methylation GO:0043414 97 0.013
ectoderm development GO:0007398 3 0.013
neuron development GO:0048666 113 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
forebrain regionalization GO:0021871 3 0.013
protein localization to plasma membrane GO:0072659 93 0.013
cell division GO:0051301 168 0.013
myeloid leukocyte differentiation GO:0002573 60 0.013
immune response GO:0006955 307 0.013
mrna metabolic process GO:0016071 175 0.013
inner ear morphogenesis GO:0042472 4 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
rho protein signal transduction GO:0007266 26 0.013
cation homeostasis GO:0055080 189 0.013
cell activation GO:0001775 213 0.013
ribonucleoprotein complex biogenesis GO:0022613 116 0.013
adult locomotory behavior GO:0008344 1 0.013
visual learning GO:0008542 1 0.012
response to lipid GO:0033993 206 0.012
protein localization to membrane GO:0072657 160 0.012
muscle cell differentiation GO:0042692 63 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
forebrain generation of neurons GO:0021872 3 0.012
response to abiotic stimulus GO:0009628 336 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
pericardium development GO:0060039 2 0.012
regeneration GO:0031099 4 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of transferase activity GO:0051338 355 0.012
forebrain development GO:0030900 26 0.012
segmentation GO:0035282 4 0.012
eye photoreceptor cell differentiation GO:0001754 2 0.012
plasma membrane organization GO:0007009 115 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
histone lysine methylation GO:0034968 50 0.012
myosin filament assembly GO:0031034 2 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
response to growth factor GO:0070848 205 0.012
heart development GO:0007507 95 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
regulation of meiosis GO:0040020 3 0.012
convergent extension GO:0060026 1 0.012
spermatid development GO:0007286 4 0.012
sodium ion transport GO:0006814 61 0.012
ion homeostasis GO:0050801 230 0.012
leukocyte activation GO:0045321 164 0.012
anterior posterior axis specification GO:0009948 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
positive regulation of locomotion GO:0040017 186 0.012
innate immune response GO:0045087 178 0.012
chemotaxis GO:0006935 157 0.012
protein dna complex subunit organization GO:0071824 80 0.011
dna repair GO:0006281 198 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
peptide transport GO:0015833 74 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
convergent extension involved in gastrulation GO:0060027 1 0.011
positive regulation of cell cycle GO:0045787 140 0.011
renal sodium ion transport GO:0003096 2 0.011
protein oligomerization GO:0051259 173 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
negative regulation of immune system process GO:0002683 136 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
embryonic morphogenesis GO:0048598 85 0.011
gtp catabolic process GO:0006184 237 0.011
hormone transport GO:0009914 68 0.011
negative regulation of cell cycle GO:0045786 193 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
peptidyl serine modification GO:0018209 106 0.011
somitogenesis GO:0001756 2 0.011
protein catabolic process GO:0030163 325 0.011
regulation of protein stability GO:0031647 87 0.011
taxis GO:0042330 157 0.011
distal tubule development GO:0072017 4 0.011
regulation of multi organism process GO:0043900 157 0.011
divalent inorganic cation transport GO:0072511 158 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
defense response GO:0006952 315 0.011
protein localization to nucleus GO:0034504 136 0.011
golgi vesicle transport GO:0048193 80 0.011
translation GO:0006412 132 0.011
positive regulation of gliogenesis GO:0014015 4 0.011
regulation of peptide secretion GO:0002791 42 0.010
lactation GO:0007595 3 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
neural tube formation GO:0001841 3 0.010
cell growth GO:0016049 160 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
sensory perception of pain GO:0019233 4 0.010
response to radiation GO:0009314 151 0.010
rna processing GO:0006396 255 0.010
cell cell signaling GO:0007267 155 0.010
leukocyte proliferation GO:0070661 74 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
regulation of actin cytoskeleton organization GO:0032956 116 0.010
tube closure GO:0060606 3 0.010
lymphocyte activation GO:0046649 133 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
hindbrain development GO:0030902 3 0.010

KIAA2026 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.044
eye and adnexa disease DOID:1492 150 0.044
nervous system disease DOID:863 431 0.044
eye disease DOID:5614 149 0.044
meckel syndrome DOID:0050778 11 0.042
myopathy DOID:423 104 0.034
muscular disease DOID:0080000 114 0.034
musculoskeletal system disease DOID:17 223 0.034
muscle tissue disease DOID:66 113 0.034
central nervous system disease DOID:331 186 0.027
neurodegenerative disease DOID:1289 102 0.018
muscular dystrophy DOID:9884 51 0.016
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
retinal disease DOID:5679 118 0.012
disease of metabolism DOID:0014667 295 0.012
retinal degeneration DOID:8466 89 0.011
spinocerebellar degeneration DOID:2478 27 0.011