Homo sapiens

2 known processes

MBD4

methyl-CpG binding domain protein 4

(Aliases: MED1)

MBD4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.325
amine metabolic process GO:0009308 44 0.259
regulation of cellular amino acid metabolic process GO:0006521 6 0.195
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.175
regulation of cytokine production GO:0001817 232 0.155
cellular macromolecule catabolic process GO:0044265 380 0.150
positive regulation of cellular amine metabolic process GO:0033240 7 0.150
chromatin modification GO:0016568 298 0.142
regulation of cellular ketone metabolic process GO:0010565 50 0.138
cellular macromolecular complex assembly GO:0034622 324 0.137
protein processing GO:0016485 226 0.134
cellular response to dna damage stimulus GO:0006974 379 0.127
Mouse
regulation of locomotion GO:0040012 329 0.124
cell activation GO:0001775 213 0.122
thymus development GO:0048538 3 0.121
regulation of leukocyte proliferation GO:0070663 67 0.115
type i interferon signaling pathway GO:0060337 11 0.112
positive regulation of cytokine production GO:0001819 167 0.109
cytokine production GO:0001816 247 0.097
leukocyte activation GO:0045321 164 0.095
regulation of proteolysis GO:0030162 293 0.095
post embryonic development GO:0009791 2 0.086
protein catabolic process GO:0030163 325 0.081
positive regulation of cell proliferation GO:0008284 301 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.077
leukocyte mediated immunity GO:0002443 59 0.074
response to abiotic stimulus GO:0009628 336 0.072
Mouse
positive regulation of locomotion GO:0040017 186 0.072
regulation of t cell activation GO:0050863 77 0.072
immune effector process GO:0002252 159 0.071
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.071
cell development GO:0048468 328 0.067
covalent chromatin modification GO:0016569 254 0.067
ubiquitin dependent protein catabolic process GO:0006511 206 0.066
regulation of cellular amine metabolic process GO:0033238 11 0.066
response to biotic stimulus GO:0009607 276 0.065
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.063
regulation of cell motility GO:2000145 299 0.063
response to other organism GO:0051707 261 0.062
positive regulation of defense response GO:0031349 87 0.062
segmentation GO:0035282 4 0.062
regulation of immune response GO:0050776 201 0.060
t cell differentiation in thymus GO:0033077 4 0.059
positive regulation of phosphorylation GO:0042327 394 0.056
lymphocyte mediated immunity GO:0002449 48 0.055
cellular protein catabolic process GO:0044257 261 0.053
mitotic cell cycle process GO:1903047 286 0.053
Mouse
negative regulation of programmed cell death GO:0043069 321 0.053
carbohydrate metabolic process GO:0005975 207 0.053
defense response GO:0006952 315 0.052
regulation of t cell migration GO:2000404 14 0.052
protein maturation GO:0051604 233 0.051
regulation of lymphocyte mediated immunity GO:0002706 33 0.051
i kappab kinase nf kappab signaling GO:0007249 166 0.047
regulation of response to external stimulus GO:0032101 222 0.046
cellular amine metabolic process GO:0044106 41 0.046
immune response GO:0006955 307 0.045
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.045
negative regulation of immune system process GO:0002683 136 0.045
female gamete generation GO:0007292 2 0.044
gland development GO:0048732 48 0.041
regulation of defense response GO:0031347 154 0.041
nuclear division GO:0000280 128 0.040
defense response to other organism GO:0098542 129 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.038
cellular response to cytokine stimulus GO:0071345 181 0.037
response to external biotic stimulus GO:0043207 261 0.037
dephosphorylation GO:0016311 209 0.037
myeloid cell differentiation GO:0030099 117 0.036
positive regulation of programmed cell death GO:0043068 249 0.036
modification dependent protein catabolic process GO:0019941 209 0.036
positive regulation of leukocyte proliferation GO:0070665 48 0.035
regulation of leukocyte activation GO:0002694 115 0.035
positive regulation of innate immune response GO:0045089 79 0.035
apoptotic signaling pathway GO:0097190 268 0.035
Mouse
negative regulation of apoptotic process GO:0043066 316 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
regulation of protein transport GO:0051223 213 0.035
regulation of lymphocyte proliferation GO:0050670 64 0.033
transmembrane transport GO:0055085 399 0.033
chromatin organization GO:0006325 351 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
positive regulation of cell death GO:0010942 263 0.032
central nervous system development GO:0007417 123 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.032
regulation of cellular response to stress GO:0080135 244 0.032
cell cycle phase transition GO:0044770 173 0.031
Mouse
positive regulation of immune system process GO:0002684 283 0.031
hematopoietic or lymphoid organ development GO:0048534 186 0.031
regulation of t cell proliferation GO:0042129 42 0.031
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.031
oocyte development GO:0048599 1 0.030
regulation of cell migration GO:0030334 289 0.030
response to molecule of bacterial origin GO:0002237 82 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
nervous system development GO:0007399 293 0.029
regulation of innate immune response GO:0045088 97 0.029
lymphocyte activation GO:0046649 133 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.028
mitotic nuclear division GO:0007067 119 0.028
response to organic cyclic compound GO:0014070 204 0.028
regulation of cellular protein catabolic process GO:1903362 96 0.028
regulation of protein processing GO:0070613 150 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
negative regulation of protein modification process GO:0031400 200 0.027
t cell activation GO:0042110 99 0.027
regulation of adaptive immune response GO:0002819 33 0.027
negative regulation of cell death GO:0060548 345 0.027
innate immune response GO:0045087 178 0.026
regulation of gene expression epigenetic GO:0040029 73 0.026
response to virus GO:0009615 126 0.025
response to lipopolysaccharide GO:0032496 70 0.025
response to oxygen containing compound GO:1901700 369 0.025
regulation of cellular component movement GO:0051270 334 0.025
lipid metabolic process GO:0006629 381 0.025
regulation of mononuclear cell proliferation GO:0032944 65 0.025
positive regulation of cell migration GO:0030335 172 0.024
regulation of protein secretion GO:0050708 86 0.024
peptidyl lysine modification GO:0018205 144 0.024
response to bacterium GO:0009617 144 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
positive regulation of t cell proliferation GO:0042102 33 0.023
regulation of homeostatic process GO:0032844 121 0.023
regulation of dephosphorylation GO:0035303 96 0.023
positive regulation of cell motility GO:2000147 177 0.022
protein dephosphorylation GO:0006470 81 0.022
multicellular organismal aging GO:0010259 3 0.022
protein ubiquitination GO:0016567 314 0.022
regulation of cell activation GO:0050865 125 0.022
regulation of intracellular transport GO:0032386 195 0.021
mitotic cell cycle GO:0000278 326 0.021
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.021
protein acylation GO:0043543 138 0.021
regulation of meiosis GO:0040020 3 0.021
double strand break repair GO:0006302 101 0.021
regulation of protein catabolic process GO:0042176 155 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.020
positive regulation of dephosphorylation GO:0035306 26 0.020
negative regulation of cell cycle GO:0045786 193 0.020
Mouse
negative regulation of locomotion GO:0040013 118 0.020
secretion by cell GO:0032940 226 0.020
response to lipid GO:0033993 206 0.020
myeloid leukocyte differentiation GO:0002573 60 0.020
stem cell division GO:0017145 2 0.019
viral process GO:0016032 146 0.019
intrinsic apoptotic signaling pathway GO:0097193 127 0.019
Mouse
positive regulation of apoptotic process GO:0043065 246 0.019
cellular protein complex assembly GO:0043623 188 0.019
locomotory behavior GO:0007626 1 0.019
positive regulation of lymphocyte proliferation GO:0050671 46 0.019
oxidation reduction process GO:0055114 396 0.019
brain development GO:0007420 97 0.018
negative regulation of proteolysis GO:0045861 132 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
embryo development GO:0009790 123 0.018
interspecies interaction between organisms GO:0044419 156 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
t cell proliferation GO:0042098 45 0.017
dna repair GO:0006281 198 0.017
adaptive immune response GO:0002250 49 0.017
response to oxidative stress GO:0006979 121 0.017
negative regulation of t cell apoptotic process GO:0070233 4 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
alcohol metabolic process GO:0006066 114 0.017
negative regulation of transport GO:0051051 176 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
positive regulation of chromosome organization GO:2001252 41 0.017
protein oligomerization GO:0051259 173 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
histone modification GO:0016570 251 0.016
lymphocyte proliferation GO:0046651 70 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
regulation of leukocyte mediated immunity GO:0002703 38 0.016
meiosis i GO:0007127 4 0.016
regulation of kinase activity GO:0043549 314 0.016
ion transmembrane transport GO:0034220 338 0.016
cellular response to growth factor stimulus GO:0071363 197 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
regulation of chromosome organization GO:0033044 103 0.015
positive regulation of immune response GO:0050778 159 0.015
protein modification by small protein removal GO:0070646 92 0.015
lymphocyte homeostasis GO:0002260 4 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
regulation of cell differentiation GO:0045595 393 0.015
regulation of cellular extravasation GO:0002691 8 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
dna recombination GO:0006310 77 0.015
secretion GO:0046903 254 0.015
rna interference GO:0016246 4 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
leukocyte proliferation GO:0070661 74 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
intracellular protein transport GO:0006886 270 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
spleen development GO:0048536 1 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
developmental process involved in reproduction GO:0003006 66 0.014
positive regulation of interleukin 8 production GO:0032757 36 0.014
response to cytokine GO:0034097 232 0.014
dna damage checkpoint GO:0000077 68 0.014
Mouse
actin filament based process GO:0030029 224 0.014
meiotic chromosome segregation GO:0045132 4 0.014
head development GO:0060322 108 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
chemical homeostasis GO:0048878 306 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
Mouse
response to fungus GO:0009620 4 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
leukocyte differentiation GO:0002521 98 0.013
oogenesis GO:0048477 2 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
vesicle mediated transport GO:0016192 371 0.013
positive regulation of immune effector process GO:0002699 40 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
protein glycosylation GO:0006486 62 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
zymogen activation GO:0031638 70 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
cellular ketone metabolic process GO:0042180 80 0.012
regulation of calcium ion transport GO:0051924 79 0.012
defense response to virus GO:0051607 71 0.012
response to growth factor GO:0070848 205 0.012
positive regulation of mononuclear cell proliferation GO:0032946 47 0.012
regulation of lymphocyte migration GO:2000401 22 0.012
positive regulation of viral entry into host cell GO:0046598 3 0.012
epithelium development GO:0060429 227 0.012
rhythmic behavior GO:0007622 2 0.012
protein dna complex assembly GO:0065004 64 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
t cell homeostasis GO:0043029 3 0.012
regulation of neurogenesis GO:0050767 82 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
cellular response to oxidative stress GO:0034599 85 0.011
glycoprotein metabolic process GO:0009100 110 0.011
histone h4 acetylation GO:0043967 47 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
regulation of cell cycle GO:0051726 393 0.011
Mouse
regulation of protein complex assembly GO:0043254 147 0.011
regulation of response to cytokine stimulus GO:0060759 46 0.011
cellular response to biotic stimulus GO:0071216 71 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
protein targeting GO:0006605 187 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of immune effector process GO:0002697 91 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
dna packaging GO:0006323 77 0.011
positive regulation of histone modification GO:0031058 29 0.011
divalent metal ion transport GO:0070838 152 0.011
actin cytoskeleton organization GO:0030036 207 0.011
regulation of viral transcription GO:0046782 34 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
t cell mediated immunity GO:0002456 25 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
regulation of cell division GO:0051302 116 0.010
generation of precursor metabolites and energy GO:0006091 68 0.010
negative regulation of gene expression epigenetic GO:0045814 19 0.010
positive regulation of cellular extravasation GO:0002693 3 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
vasculature development GO:0001944 181 0.010
viral life cycle GO:0019058 132 0.010
regulation of cellular component biogenesis GO:0044087 281 0.010
protein alkylation GO:0008213 74 0.010
protein methylation GO:0006479 74 0.010
negative regulation of protein maturation GO:1903318 142 0.010
positive regulation of developmental process GO:0051094 314 0.010
hemopoiesis GO:0030097 180 0.010
protein polyubiquitination GO:0000209 110 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
blood vessel development GO:0001568 172 0.010
neuron death GO:0070997 65 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
regulation of membrane potential GO:0042391 95 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010

MBD4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.049
central nervous system disease DOID:331 186 0.038
nervous system disease DOID:863 431 0.038
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
musculoskeletal system disease DOID:17 223 0.020
disease of metabolism DOID:0014667 295 0.016
inherited metabolic disorder DOID:655 242 0.016
carbohydrate metabolic disorder DOID:2978 55 0.013