Homo sapiens

16 known processes

ARIH1

ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)

(Aliases: HARI,DKFZp686O13120,FLJ93118,HHARI,FLJ20329,ARI,UBCH7BP)

ARIH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 314 0.985
protein modification by small protein conjugation GO:0032446 342 0.971
cellular protein catabolic process GO:0044257 261 0.832
Human Mouse Fly
protein polyubiquitination GO:0000209 110 0.718
Human
modification dependent protein catabolic process GO:0019941 209 0.676
Human Mouse Fly
modification dependent macromolecule catabolic process GO:0043632 212 0.659
Human Mouse Fly
cellular macromolecule catabolic process GO:0044265 380 0.599
Human Mouse Fly
proteasomal protein catabolic process GO:0010498 176 0.315
ubiquitin dependent protein catabolic process GO:0006511 206 0.309
Human Mouse Fly
regulation of protein ubiquitination GO:0031396 95 0.248
negative regulation of glial cell proliferation GO:0060253 2 0.236
histone ubiquitination GO:0016574 31 0.190
oogenesis GO:0048477 2 0.183
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.176
Human Mouse Fly
protein deubiquitination GO:0016579 79 0.166
female gamete generation GO:0007292 2 0.165
Fly
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.157
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.135
protein glycosylation GO:0006486 62 0.135
protein catabolic process GO:0030163 325 0.127
Human Mouse Fly
post embryonic development GO:0009791 2 0.126
protein modification by small protein removal GO:0070646 92 0.124
single organism cellular localization GO:1902580 332 0.117
histone modification GO:0016570 251 0.109
hexose metabolic process GO:0019318 55 0.109
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.109
glycoprotein biosynthetic process GO:0009101 91 0.107
rhythmic behavior GO:0007622 2 0.103
chromatin modification GO:0016568 298 0.103
regulation of ubiquitin protein transferase activity GO:0051438 28 0.101
protein k48 linked ubiquitination GO:0070936 38 0.099
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.098
regulation of cellular ketone metabolic process GO:0010565 50 0.097
protein monoubiquitination GO:0006513 39 0.094
organelle fission GO:0048285 149 0.093
regulation of proteolysis GO:0030162 293 0.090
determination of adult lifespan GO:0008340 2 0.090
vesicle mediated transport GO:0016192 371 0.085
locomotory behavior GO:0007626 1 0.084
protein localization to organelle GO:0033365 280 0.082
positive regulation of cellular component organization GO:0051130 376 0.076
chromatin organization GO:0006325 351 0.075
negative regulation of protein metabolic process GO:0051248 391 0.074
system process GO:0003008 349 0.073
mitotic cell cycle GO:0000278 326 0.073
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.070
Human Fly
behavior GO:0007610 112 0.070
wnt signaling pathway GO:0016055 156 0.066
cellular response to hormone stimulus GO:0032870 125 0.065
positive regulation of transport GO:0051050 336 0.065
cellular response to endogenous stimulus GO:0071495 336 0.064
multicellular organismal aging GO:0010259 3 0.063
cellular component morphogenesis GO:0032989 314 0.062
canonical wnt signaling pathway GO:0060070 116 0.062
regulation of ligase activity GO:0051340 29 0.060
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.060
circadian behavior GO:0048512 2 0.058
regulation of glial cell proliferation GO:0060251 4 0.057
covalent chromatin modification GO:0016569 254 0.056
regulation of cell cycle process GO:0010564 266 0.056
regulation of chromosome organization GO:0033044 103 0.055
regulation of cell cycle GO:0051726 393 0.054
maintenance of location GO:0051235 112 0.053
regulation of dna metabolic process GO:0051052 153 0.053
negative regulation of cell death GO:0060548 345 0.053
dna repair GO:0006281 198 0.053
positive regulation of programmed cell death GO:0043068 249 0.052
regulation of protein stability GO:0031647 87 0.052
endocytosis GO:0006897 159 0.052
macromolecule glycosylation GO:0043413 63 0.051
single organism carbohydrate metabolic process GO:0044723 193 0.051
negative regulation of apoptotic process GO:0043066 316 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.050
neural tube formation GO:0001841 3 0.050
organ morphogenesis GO:0009887 147 0.049
carbohydrate metabolic process GO:0005975 207 0.048
regulation of tor signaling GO:0032006 30 0.048
dna damage checkpoint GO:0000077 68 0.046
mitotic cell cycle process GO:1903047 286 0.046
nucleotide catabolic process GO:0009166 408 0.045
regulation of protein complex assembly GO:0043254 147 0.045
lipid storage GO:0019915 28 0.044
positive regulation of wnt signaling pathway GO:0030177 54 0.044
cellular amino acid metabolic process GO:0006520 116 0.043
regulation of peptidase activity GO:0052547 180 0.043
regulation of proteasomal protein catabolic process GO:0061136 87 0.043
organelle localization GO:0051640 84 0.042
dna packaging GO:0006323 77 0.042
cell morphogenesis GO:0000902 296 0.041
memory GO:0007613 3 0.041
nuclear division GO:0000280 128 0.041
regulation of cytoplasmic transport GO:1903649 149 0.040
metencephalon development GO:0022037 2 0.040
cardiovascular system development GO:0072358 262 0.040
cellular ketone metabolic process GO:0042180 80 0.040
dephosphorylation GO:0016311 209 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.039
regulation of kinase activity GO:0043549 314 0.039
segmentation GO:0035282 4 0.039
cell cycle checkpoint GO:0000075 117 0.038
nucleoside catabolic process GO:0009164 408 0.038
circulatory system development GO:0072359 262 0.038
regulation of cellular response to stress GO:0080135 244 0.037
oocyte development GO:0048599 1 0.037
mononuclear cell proliferation GO:0032943 71 0.036
regulation of response to dna damage stimulus GO:2001020 94 0.035
positive regulation of organelle organization GO:0010638 195 0.035
regulation of nucleotide metabolic process GO:0006140 269 0.035
cytoplasmic transport GO:0016482 379 0.034
microtubule based process GO:0007017 210 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
enzyme linked receptor protein signaling pathway GO:0007167 303 0.034
negative regulation of transport GO:0051051 176 0.034
establishment of protein localization to organelle GO:0072594 172 0.033
negative regulation of cellular component organization GO:0051129 235 0.032
positive regulation of proteolysis GO:0045862 142 0.032
monosaccharide metabolic process GO:0005996 74 0.031
protein dephosphorylation GO:0006470 81 0.031
amine metabolic process GO:0009308 44 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
regulation of transferase activity GO:0051338 355 0.031
cellular macromolecular complex assembly GO:0034622 324 0.030
nitrogen compound transport GO:0071705 191 0.030
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.030
regulation of intracellular transport GO:0032386 195 0.030
glycosyl compound catabolic process GO:1901658 413 0.029
response to external biotic stimulus GO:0043207 261 0.029
regulation of binding GO:0051098 111 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.028
neuron remodeling GO:0016322 2 0.028
cellular homeostasis GO:0019725 196 0.028
response to hormone GO:0009725 175 0.028
regulation of protein transport GO:0051223 213 0.028
neurological system process GO:0050877 163 0.028
peptide transport GO:0015833 74 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
receptor mediated endocytosis GO:0006898 84 0.027
mitochondrion organization GO:0007005 156 0.027
ribonucleotide catabolic process GO:0009261 405 0.026
regulation of glucose metabolic process GO:0010906 28 0.026
regulation of canonical wnt signaling pathway GO:0060828 88 0.026
protein localization to nucleus GO:0034504 136 0.026
negative regulation of protein maturation GO:1903318 142 0.026
regulation of cell division GO:0051302 116 0.026
apoptotic signaling pathway GO:0097190 268 0.026
signal transduction by phosphorylation GO:0023014 297 0.025
response to uv GO:0009411 73 0.025
positive regulation of protein ubiquitination GO:0031398 53 0.025
protein import GO:0017038 130 0.025
negative regulation of proteolysis GO:0045861 132 0.025
cellular protein complex assembly GO:0043623 188 0.024
g2 m transition of mitotic cell cycle GO:0000086 41 0.024
regulation of establishment of protein localization GO:0070201 242 0.023
protein homooligomerization GO:0051260 100 0.023
regulation of centrosome cycle GO:0046605 15 0.023
regulation of cytokine production GO:0001817 232 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
cell development GO:0048468 328 0.023
Human Fly
negative regulation of catalytic activity GO:0043086 335 0.023
anterior posterior axis specification GO:0009948 2 0.023
transmembrane transport GO:0055085 399 0.023
cellular response to dna damage stimulus GO:0006974 379 0.022
positive regulation of rab gtpase activity GO:0032851 39 0.022
immune response GO:0006955 307 0.022
regulation of response to external stimulus GO:0032101 222 0.022
oocyte differentiation GO:0009994 2 0.022
organophosphate catabolic process GO:0046434 430 0.022
response to oxygen containing compound GO:1901700 369 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.022
microtubule organizing center organization GO:0031023 62 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
dna integrity checkpoint GO:0031570 71 0.022
protein stabilization GO:0050821 64 0.022
glucose metabolic process GO:0006006 45 0.022
negative regulation of protein modification process GO:0031400 200 0.021
meiotic chromosome segregation GO:0045132 4 0.021
membrane organization GO:0061024 292 0.021
growth GO:0040007 202 0.021
Human
regulation of cytoskeleton organization GO:0051493 177 0.021
regulation of cellular protein catabolic process GO:1903362 96 0.021
intracellular protein transport GO:0006886 270 0.021
positive regulation of transferase activity GO:0051347 227 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
positive regulation of cell death GO:0010942 263 0.020
nervous system development GO:0007399 293 0.020
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.020
protein k48 linked deubiquitination GO:0071108 19 0.020
long term memory GO:0007616 2 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
dna conformation change GO:0071103 113 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
developmental process involved in reproduction GO:0003006 66 0.019
Fly
regulation of protein catabolic process GO:0042176 155 0.019
defense response GO:0006952 315 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
golgi vesicle transport GO:0048193 80 0.019
nucleocytoplasmic transport GO:0006913 176 0.018
negative regulation of multi organism process GO:0043901 92 0.018
positive regulation of intracellular transport GO:0032388 104 0.018
nf kappab import into nucleus GO:0042348 22 0.018
regulation of carbohydrate metabolic process GO:0006109 54 0.018
neurogenesis GO:0022008 169 0.018
Fly
chemical homeostasis GO:0048878 306 0.018
negative regulation of immune system process GO:0002683 136 0.018
amide transport GO:0042886 76 0.018
negative regulation of protein ubiquitination GO:0031397 35 0.017
response to biotic stimulus GO:0009607 276 0.017
reproductive structure development GO:0048608 55 0.017
positive regulation of immune system process GO:0002684 283 0.017
positive regulation of cytoplasmic transport GO:1903651 82 0.017
lipid localization GO:0010876 106 0.017
regulation of microtubule cytoskeleton organization GO:0070507 61 0.017
embryo development GO:0009790 123 0.017
negative regulation of binding GO:0051100 57 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
single organism membrane organization GO:0044802 268 0.016
maintenance of protein location GO:0045185 57 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
methylation GO:0032259 106 0.016
regulation of mitosis GO:0007088 63 0.016
regulation of cell differentiation GO:0045595 393 0.016
Fly
reproduction GO:0000003 63 0.016
Fly
cell type specific apoptotic process GO:0097285 125 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
cell cycle g2 m phase transition GO:0044839 43 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
regulation of chromatin organization GO:1902275 56 0.016
response to growth factor GO:0070848 205 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
mitotic nuclear division GO:0007067 119 0.016
positive regulation of protein transport GO:0051222 135 0.016
spermatid differentiation GO:0048515 4 0.016
regulation of immune response GO:0050776 201 0.015
regulation of protein kinase activity GO:0045859 289 0.015
neuron development GO:0048666 113 0.015
neural tube closure GO:0001843 3 0.015
nuclear transport GO:0051169 179 0.015
intracellular mrna localization GO:0008298 1 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
regulation of nf kappab import into nucleus GO:0042345 22 0.015
cellular response to radiation GO:0071478 65 0.015
regulation of protein localization GO:0032880 296 0.015
centrosome organization GO:0051297 58 0.015
glycosylation GO:0070085 71 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
regulation of response to wounding GO:1903034 101 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
vasculature development GO:0001944 181 0.015
response to virus GO:0009615 126 0.015
cell part morphogenesis GO:0032990 137 0.015
positive regulation of cytokine production GO:0001819 167 0.015
regulation of rab gtpase activity GO:0032313 39 0.015
negative regulation of developmental process GO:0051093 247 0.015
nucleus localization GO:0051647 1 0.015
centrosome cycle GO:0007098 32 0.015
hindbrain development GO:0030902 3 0.015
cell projection morphogenesis GO:0048858 129 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
demethylation GO:0070988 37 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
regulation of nuclear division GO:0051783 65 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
histone h2a ubiquitination GO:0033522 17 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
rna localization GO:0006403 41 0.014
tripartite regional subdivision GO:0007351 2 0.014
reproductive process GO:0022414 106 0.014
Fly
centrosome separation GO:0051299 3 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
protein targeting GO:0006605 187 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
response to nitrogen compound GO:1901698 184 0.013
innate immune response GO:0045087 178 0.013
neuroblast proliferation GO:0007405 4 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
tube closure GO:0060606 3 0.013
generation of neurons GO:0048699 152 0.013
Fly
regulation of protein targeting GO:1903533 91 0.013
developmental maturation GO:0021700 28 0.013
ras protein signal transduction GO:0007265 73 0.013
regulation of histone modification GO:0031056 47 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
nuclear import GO:0051170 106 0.013
stem cell division GO:0017145 2 0.013
regulation of multi organism process GO:0043900 157 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
single organism nuclear import GO:1902593 104 0.013
positive regulation of secretion GO:0051047 116 0.013
cytokine production GO:0001816 247 0.013
somitogenesis GO:0001756 2 0.012
response to other organism GO:0051707 261 0.012
associative learning GO:0008306 1 0.012
regulation of peptide transport GO:0090087 62 0.012
blastoderm segmentation GO:0007350 2 0.012
response to abiotic stimulus GO:0009628 336 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
regulation of dna binding GO:0051101 37 0.012
aging GO:0007568 66 0.012
cell division GO:0051301 168 0.012
activation of immune response GO:0002253 114 0.012
regulation of defense response GO:0031347 154 0.012
negative regulation of dna metabolic process GO:0051053 57 0.012
response to transforming growth factor beta GO:0071559 94 0.012
cellular response to peptide GO:1901653 59 0.012
respiratory tube development GO:0030323 20 0.012
response to bacterium GO:0009617 144 0.012
actin cytoskeleton organization GO:0030036 207 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
negative regulation of chromatin modification GO:1903309 21 0.011
cell projection organization GO:0030030 252 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
regulation of cell development GO:0060284 161 0.011
Fly
glycoprotein metabolic process GO:0009100 110 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
heart morphogenesis GO:0003007 48 0.011
multicellular organism reproduction GO:0032504 42 0.011
Fly
spermatid development GO:0007286 4 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
secretion by cell GO:0032940 226 0.011
reproductive system development GO:0061458 56 0.011
jnk cascade GO:0007254 80 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
developmental programmed cell death GO:0010623 3 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
regulation of cell activation GO:0050865 125 0.011
neuron differentiation GO:0030182 138 0.011
rab protein signal transduction GO:0032482 4 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
meiosis i GO:0007127 4 0.011
mitochondrion distribution GO:0048311 3 0.010
blood vessel morphogenesis GO:0048514 162 0.010
striated muscle myosin thick filament assembly GO:0071688 2 0.010
gtp metabolic process GO:0046039 239 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010
regulation of leukocyte activation GO:0002694 115 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
response to radiation GO:0009314 151 0.010
cellular response to insulin stimulus GO:0032869 41 0.010
regulation of rab protein signal transduction GO:0032483 39 0.010
defense response to bacterium GO:0042742 63 0.010
negative regulation of protein localization to nucleus GO:1900181 34 0.010

ARIH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.022