Homo sapiens

69 known processes

PDX1

pancreatic and duodenal homeobox 1

(Aliases: IPF1,GSF,IUF1,IDX-1,MODY4,PDX-1,STF-1)

PDX1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
peptide secretion GO:0002790 51 0.987
neuron fate commitment GO:0048663 2 0.983
hormone secretion GO:0046879 65 0.975
organ morphogenesis GO:0009887 147 0.966
regulation of cell differentiation GO:0045595 393 0.952
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.940
Mouse
cell cell signaling GO:0007267 155 0.939
regulation of hormone levels GO:0010817 125 0.935
signal release GO:0023061 70 0.894
endocrine system development GO:0035270 26 0.887
peptide transport GO:0015833 74 0.877
negative regulation of cell differentiation GO:0045596 171 0.848
positive regulation of developmental process GO:0051094 314 0.846
cardiovascular system development GO:0072358 262 0.833
skeletal system development GO:0001501 79 0.832
vasculature development GO:0001944 181 0.813
response to oxygen containing compound GO:1901700 369 0.809
Mouse
peptide hormone secretion GO:0030072 50 0.799
cell differentiation in spinal cord GO:0021515 1 0.789
mesenchyme development GO:0060485 59 0.789
hindbrain development GO:0030902 3 0.784
amide transport GO:0042886 76 0.783
hormone transport GO:0009914 68 0.770
pancreatic a cell differentiation GO:0003310 1 0.755
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.717
nitrogen compound transport GO:0071705 191 0.706
positive regulation of cell differentiation GO:0045597 211 0.674
specification of organ identity GO:0010092 3 0.663
epithelium development GO:0060429 227 0.657
secretion by cell GO:0032940 226 0.614
negative regulation of multicellular organismal process GO:0051241 317 0.598
cardiac cell fate determination GO:0060913 3 0.569
stem cell development GO:0048864 69 0.564
secretion GO:0046903 254 0.563
insulin secretion GO:0030073 39 0.562
forebrain generation of neurons GO:0021872 3 0.545
regulation of locomotion GO:0040012 329 0.526
extraocular skeletal muscle development GO:0002074 1 0.513
cranial nerve development GO:0021545 4 0.495
anatomical structure formation involved in morphogenesis GO:0048646 284 0.489
cellular component morphogenesis GO:0032989 314 0.481
embryonic morphogenesis GO:0048598 85 0.478
Mouse
spinal cord development GO:0021510 4 0.471
negative regulation of developmental process GO:0051093 247 0.458
central nervous system development GO:0007417 123 0.458
cardiac right ventricle morphogenesis GO:0003215 3 0.446
aortic valve development GO:0003176 3 0.412
circulatory system development GO:0072359 262 0.406
response to carbohydrate GO:0009743 21 0.387
Mouse
regulation of cell motility GO:2000145 299 0.386
regulation of cellular ketone metabolic process GO:0010565 50 0.385
positive regulation of cell proliferation GO:0008284 301 0.383
Mouse
cell morphogenesis GO:0000902 296 0.382
pattern specification process GO:0007389 43 0.374
Zebrafish
forebrain neuron differentiation GO:0021879 3 0.368
male gonad development GO:0008584 23 0.363
trophectodermal cell differentiation GO:0001829 3 0.359
cell fate determination GO:0001709 3 0.357
menstrual cycle phase GO:0022601 2 0.355
organ formation GO:0048645 3 0.354
cardiac ventricle formation GO:0003211 2 0.352
neuron differentiation GO:0030182 138 0.352
positive regulation of cell development GO:0010720 92 0.346
immune system development GO:0002520 195 0.343
head development GO:0060322 108 0.319
blood vessel development GO:0001568 172 0.304
metencephalon development GO:0022037 2 0.301
cell fate specification GO:0001708 8 0.281
regulation of cell development GO:0060284 161 0.279
epithelial cell differentiation GO:0030855 141 0.277
development of primary male sexual characteristics GO:0046546 23 0.276
cell morphogenesis involved in differentiation GO:0000904 144 0.275
cell development GO:0048468 328 0.268
blastocyst development GO:0001824 3 0.257
globus pallidus development GO:0021759 1 0.255
system process GO:0003008 349 0.254
digestive system development GO:0055123 75 0.253
Zebrafish Mouse
regulation of neurogenesis GO:0050767 82 0.249
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.247
nitric oxide mediated signal transduction GO:0007263 7 0.244
regulation of secretion GO:0051046 194 0.243
Mouse
response to hormone GO:0009725 175 0.243
nerve development GO:0021675 4 0.242
positive regulation of cellular component movement GO:0051272 181 0.242
ventral spinal cord development GO:0021517 1 0.235
tube development GO:0035295 125 0.233
Zebrafish Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.231
limbic system development GO:0021761 3 0.230
male sex differentiation GO:0046661 25 0.229
neuron projection development GO:0031175 106 0.221
embryo development GO:0009790 123 0.213
Mouse
locomotory behavior GO:0007626 1 0.211
mesenchymal cell differentiation GO:0048762 52 0.210
negative regulation of cellular component movement GO:0051271 106 0.204
striated muscle tissue development GO:0014706 59 0.193
brain development GO:0007420 97 0.192
cardiac left ventricle formation GO:0003218 1 0.192
cell projection organization GO:0030030 252 0.191
response to hexose GO:0009746 20 0.187
Mouse
response to organic cyclic compound GO:0014070 204 0.185
reproductive process GO:0022414 106 0.185
gland development GO:0048732 48 0.173
Zebrafish Mouse
blastocyst formation GO:0001825 3 0.173
regulation of cell cycle GO:0051726 393 0.171
negative regulation of cell development GO:0010721 48 0.171
optic nerve development GO:0021554 2 0.171
cardiac right ventricle formation GO:0003219 1 0.166
regulation of anatomical structure morphogenesis GO:0022603 286 0.166
segmentation GO:0035282 4 0.166
regulation of cell migration GO:0030334 289 0.165
oxidation reduction process GO:0055114 396 0.163
behavior GO:0007610 112 0.162
regulation of peptide secretion GO:0002791 42 0.159
Mouse
forebrain regionalization GO:0021871 3 0.156
regulation of cellular amine metabolic process GO:0033238 11 0.153
regulation of cellular component movement GO:0051270 334 0.151
signal transduction involved in regulation of gene expression GO:0023019 1 0.148
female gonad development GO:0008585 10 0.147
chordate embryonic development GO:0043009 34 0.147
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.146
positive regulation of locomotion GO:0040017 186 0.144
regulation of cellular amino acid metabolic process GO:0006521 6 0.141
positive regulation of nervous system development GO:0051962 54 0.135
cellular amino acid metabolic process GO:0006520 116 0.134
response to organonitrogen compound GO:0010243 156 0.133
response to nitrogen compound GO:1901698 184 0.133
regulation of secretion by cell GO:1903530 177 0.132
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.129
peripheral nervous system development GO:0007422 2 0.128
positive regulation of stem cell differentiation GO:2000738 29 0.127
lipid modification GO:0030258 84 0.127
organonitrogen compound biosynthetic process GO:1901566 200 0.125
glandular epithelial cell differentiation GO:0002067 6 0.125
regulation of epithelial to mesenchymal transition GO:0010717 37 0.123
embryonic camera type eye development GO:0031076 2 0.122
hematopoietic or lymphoid organ development GO:0048534 186 0.121
forebrain development GO:0030900 26 0.121
protein oligomerization GO:0051259 173 0.119
negative regulation of stem cell differentiation GO:2000737 22 0.119
cell proliferation involved in heart valve development GO:2000793 1 0.118
nervous system development GO:0007399 293 0.118
cellular amine metabolic process GO:0044106 41 0.116
monocarboxylic acid metabolic process GO:0032787 185 0.114
heart formation GO:0060914 2 0.113
amine metabolic process GO:0009308 44 0.111
cation transmembrane transport GO:0098655 238 0.109
embryonic organ development GO:0048568 36 0.109
single organism reproductive process GO:0044702 98 0.107
reproductive system development GO:0061458 56 0.107
response to glucose GO:0009749 19 0.107
Mouse
kidney development GO:0001822 53 0.107
reproductive structure development GO:0048608 55 0.106
negative regulation of programmed cell death GO:0043069 321 0.105
Mouse
post embryonic development GO:0009791 2 0.104
heart field specification GO:0003128 2 0.103
transmembrane transport GO:0055085 399 0.103
stem cell differentiation GO:0048863 93 0.102
cellular response to hormone stimulus GO:0032870 125 0.101
tissue morphogenesis GO:0048729 96 0.101
Mouse
regulation of insulin secretion GO:0050796 33 0.098
Mouse
mitotic cell cycle GO:0000278 326 0.095
cardiac chamber morphogenesis GO:0003206 26 0.095
regulation of transferase activity GO:0051338 355 0.094
gabaergic neuron differentiation GO:0097154 1 0.094
regulation of mitotic cell cycle GO:0007346 189 0.093
central nervous system neuron differentiation GO:0021953 9 0.093
negative regulation of cellular component organization GO:0051129 235 0.092
generation of neurons GO:0048699 152 0.091
regulation of neuron differentiation GO:0045664 70 0.091
regulation of cell morphogenesis GO:0022604 153 0.090
negative regulation of phosphate metabolic process GO:0045936 267 0.089
sex differentiation GO:0007548 45 0.088
tube morphogenesis GO:0035239 95 0.087
positive regulation of neuron differentiation GO:0045666 40 0.086
epithelial to mesenchymal transition GO:0001837 48 0.084
regionalization GO:0003002 29 0.084
mesonephric duct development GO:0072177 3 0.083
peptidyl tyrosine modification GO:0018212 170 0.083
cellular response to oxygen containing compound GO:1901701 276 0.083
Mouse
chromatin organization GO:0006325 351 0.082
leukocyte differentiation GO:0002521 98 0.081
embryonic organ morphogenesis GO:0048562 24 0.081
developmental process involved in reproduction GO:0003006 66 0.080
cardiac ventricle development GO:0003231 23 0.080
negative regulation of cellular protein metabolic process GO:0032269 353 0.080
forebrain dorsal ventral pattern formation GO:0021798 1 0.080
wnt signaling pathway GO:0016055 156 0.080
negative regulation of locomotion GO:0040013 118 0.079
regulation of kinase activity GO:0043549 314 0.079
fatty acid metabolic process GO:0006631 115 0.078
cardiac chamber formation GO:0003207 2 0.078
cellular ketone metabolic process GO:0042180 80 0.078
mating GO:0007618 1 0.077
lipid biosynthetic process GO:0008610 177 0.077
neurogenesis GO:0022008 169 0.076
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.075
cellular response to dna damage stimulus GO:0006974 379 0.074
regulation of hormone secretion GO:0046883 57 0.074
Mouse
spinal cord dorsal ventral patterning GO:0021513 2 0.073
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.073
regulation of peptide transport GO:0090087 62 0.072
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.072
renal system development GO:0072001 63 0.072
cellular response to endogenous stimulus GO:0071495 336 0.071
connective tissue development GO:0061448 39 0.071
neuroendocrine cell differentiation GO:0061101 2 0.071
positive regulation of epithelial cell proliferation GO:0050679 65 0.070
forelimb morphogenesis GO:0035136 4 0.070
chromatin modification GO:0016568 298 0.069
positive regulation of programmed cell death GO:0043068 249 0.069
neuron projection morphogenesis GO:0048812 50 0.068
regulation of methylation dependent chromatin silencing GO:0090308 3 0.066
positive regulation of immune system process GO:0002684 283 0.065
second messenger mediated signaling GO:0019932 78 0.065
gonad development GO:0008406 34 0.064
adult locomotory behavior GO:0008344 1 0.064
negative regulation of apoptotic process GO:0043066 316 0.064
Mouse
morphogenesis of an epithelium GO:0002009 60 0.064
Mouse
epithelial cell fate commitment GO:0072148 3 0.064
myeloid leukocyte differentiation GO:0002573 60 0.063
positive regulation of protein kinase activity GO:0045860 190 0.063
basophil differentiation GO:0030221 2 0.061
regulation of epithelial cell proliferation GO:0050678 113 0.061
regulation of stem cell differentiation GO:2000736 56 0.061
mesenchymal cell development GO:0014031 50 0.061
hemopoiesis GO:0030097 180 0.060
female sex differentiation GO:0046660 12 0.060
embryonic skeletal system development GO:0048706 13 0.060
endodermal cell fate specification GO:0001714 4 0.059
regulation of growth GO:0040008 165 0.059
activation of protein kinase activity GO:0032147 90 0.059
growth GO:0040007 202 0.059
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.058
cell fate commitment involved in pattern specification GO:0060581 1 0.058
negative regulation of cell death GO:0060548 345 0.058
Mouse
lipid oxidation GO:0034440 33 0.058
angiogenesis GO:0001525 147 0.058
blood vessel maturation GO:0001955 1 0.057
regulation of protein serine threonine kinase activity GO:0071900 179 0.057
embryonic eye morphogenesis GO:0048048 2 0.057
regulation of nervous system development GO:0051960 88 0.056
inorganic ion transmembrane transport GO:0098660 231 0.056
response to drug GO:0042493 81 0.056
regulation of protein kinase activity GO:0045859 289 0.056
response to lipid GO:0033993 206 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
ventral spinal cord interneuron differentiation GO:0021514 1 0.055
positive regulation of catabolic process GO:0009896 310 0.055
positive regulation of cellular amine metabolic process GO:0033240 7 0.054
embryonic camera type eye formation GO:0060900 2 0.053
hippocampus development GO:0021766 1 0.053
positive regulation of transferase activity GO:0051347 227 0.053
cardiac muscle cell contraction GO:0086003 4 0.053
ameboidal type cell migration GO:0001667 135 0.053
regulation of protein localization GO:0032880 296 0.053
steroid metabolic process GO:0008202 94 0.052
positive regulation of secretion GO:0051047 116 0.052
Mouse
peptidyl tyrosine phosphorylation GO:0018108 170 0.052
negative regulation of cell motility GO:2000146 104 0.052
somatic stem cell maintenance GO:0035019 4 0.052
regulation of wnt signaling pathway GO:0030111 123 0.051
morphogenesis of embryonic epithelium GO:0016331 4 0.051
Mouse
cellular homeostasis GO:0019725 196 0.051
Mouse
regulation of organ morphogenesis GO:2000027 24 0.051
positive regulation of cell death GO:0010942 263 0.051
cellular lipid metabolic process GO:0044255 303 0.050
small molecule biosynthetic process GO:0044283 157 0.049
response to peptide GO:1901652 65 0.049
regulation of homeostatic process GO:0032844 121 0.049
Mouse
mesodermal cell fate specification GO:0007501 2 0.049
histone modification GO:0016570 251 0.049
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.049
positive regulation of apoptotic process GO:0043065 246 0.048
lipid metabolic process GO:0006629 381 0.048
actin filament based process GO:0030029 224 0.048
chromatin assembly or disassembly GO:0006333 78 0.048
endodermal cell fate commitment GO:0001711 4 0.047
organic hydroxy compound metabolic process GO:1901615 147 0.047
chemical homeostasis GO:0048878 306 0.047
Mouse
development of primary female sexual characteristics GO:0046545 10 0.047
glucose homeostasis GO:0042593 31 0.047
Mouse
membrane organization GO:0061024 292 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
lipid catabolic process GO:0016042 84 0.046
cellular response to organonitrogen compound GO:0071417 124 0.046
axonogenesis GO:0007409 31 0.046
developmental programmed cell death GO:0010623 3 0.046
negative regulation of protein modification process GO:0031400 200 0.045
cellular response to nitrogen compound GO:1901699 144 0.045
regulation of lipid metabolic process GO:0019216 96 0.045
embryo development ending in birth or egg hatching GO:0009792 34 0.045
menstruation GO:0042703 1 0.045
cell type specific apoptotic process GO:0097285 125 0.044
Mouse
bmp signaling pathway involved in heart development GO:0061312 3 0.044
regulation of cellular response to stress GO:0080135 244 0.044
Mouse
regulation of protein transport GO:0051223 213 0.044
embryonic forelimb morphogenesis GO:0035115 4 0.044
epidermis development GO:0008544 59 0.043
response to abiotic stimulus GO:0009628 336 0.043
determination of adult lifespan GO:0008340 2 0.043
biological adhesion GO:0022610 331 0.043
testosterone biosynthetic process GO:0061370 2 0.043
cell part morphogenesis GO:0032990 137 0.043
cell projection morphogenesis GO:0048858 129 0.043
negative regulation of phosphorylation GO:0042326 174 0.042
positive regulation of kinase activity GO:0033674 204 0.042
gastrulation GO:0007369 51 0.042
ventricular cardiac muscle tissue development GO:0003229 14 0.041
single organism cellular localization GO:1902580 332 0.041
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.041
pancreas development GO:0031016 19 0.041
positive regulation of myeloid cell differentiation GO:0045639 39 0.041
response to monosaccharide GO:0034284 20 0.041
Mouse
embryonic epithelial tube formation GO:0001838 4 0.041
kidney morphogenesis GO:0060993 19 0.040
cell fate commitment GO:0045165 27 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
bone mineralization GO:0030282 34 0.040
associative learning GO:0008306 1 0.040
digestive tract development GO:0048565 75 0.040
Zebrafish Mouse
organic acid catabolic process GO:0016054 71 0.040
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.040
organic hydroxy compound biosynthetic process GO:1901617 71 0.039
nucleocytoplasmic transport GO:0006913 176 0.039
positive regulation of cellular catabolic process GO:0031331 284 0.039
neuron development GO:0048666 113 0.039
positive regulation of cell division GO:0051781 59 0.039
regulation of erythrocyte differentiation GO:0045646 17 0.039
regulation of protein complex assembly GO:0043254 147 0.039
positive regulation of cytokine production GO:0001819 167 0.038
cerebellum development GO:0021549 2 0.038
ion homeostasis GO:0050801 230 0.038
epithelial cell proliferation GO:0050673 128 0.038
negative regulation of cell migration GO:0030336 102 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
hematopoietic stem cell differentiation GO:0060218 4 0.038
erythrocyte differentiation GO:0030218 28 0.038
alcohol metabolic process GO:0006066 114 0.037
nephron epithelium development GO:0072009 23 0.037
enteroendocrine cell differentiation GO:0035883 6 0.037
pharynx development GO:0060465 1 0.037
positive regulation of transport GO:0051050 336 0.037
Mouse
regulation of dna metabolic process GO:0051052 153 0.036
cardiac muscle tissue development GO:0048738 39 0.036
enzyme linked receptor protein signaling pathway GO:0007167 303 0.036
heart development GO:0007507 95 0.036
cation transport GO:0006812 331 0.036
cardiocyte differentiation GO:0035051 23 0.036
amide biosynthetic process GO:0043604 15 0.035
blood vessel morphogenesis GO:0048514 162 0.035
forebrain neuron development GO:0021884 2 0.035
taxis GO:0042330 157 0.035
developmental growth GO:0048589 48 0.035
regulation of cysteine type endopeptidase activity GO:2000116 127 0.035
protein localization to nucleus GO:0034504 136 0.035
cardiac muscle tissue morphogenesis GO:0055008 18 0.035
heart morphogenesis GO:0003007 48 0.035
negative regulation of organelle organization GO:0010639 126 0.035
regulation of heart induction GO:0090381 2 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
anatomical structure homeostasis GO:0060249 100 0.034
positive regulation of mitotic cell cycle GO:0045931 60 0.034
regulation of lipid catabolic process GO:0050994 23 0.034
multicellular organismal aging GO:0010259 3 0.034
immune response GO:0006955 307 0.034
kidney epithelium development GO:0072073 25 0.034
steroid biosynthetic process GO:0006694 46 0.033
neurological system process GO:0050877 163 0.033
regeneration GO:0031099 4 0.033
anion transport GO:0006820 161 0.033
negative regulation of cell proliferation GO:0008285 228 0.033
Mouse
inner ear morphogenesis GO:0042472 4 0.033
single organism membrane organization GO:0044802 268 0.033
organophosphate biosynthetic process GO:0090407 163 0.033
sensory perception of pain GO:0019233 4 0.033
mapk cascade GO:0000165 288 0.033
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.032
postsynaptic membrane organization GO:0001941 2 0.032
sensory organ development GO:0007423 52 0.032
mitotic cell cycle process GO:1903047 286 0.032
development of primary sexual characteristics GO:0045137 35 0.032
memory GO:0007613 3 0.032
regulation of endopeptidase activity GO:0052548 170 0.032
negative regulation of histone phosphorylation GO:0033128 2 0.031
cellular response to corticotropin releasing hormone stimulus GO:0071376 1 0.031
positive regulation of cell migration GO:0030335 172 0.031
cell division GO:0051301 168 0.031
carbohydrate metabolic process GO:0005975 207 0.031
Mouse
muscle contraction GO:0006936 73 0.031
nephric duct development GO:0072176 4 0.031
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.031
blastoderm segmentation GO:0007350 2 0.031
telencephalon development GO:0021537 17 0.030
negative regulation of transport GO:0051051 176 0.030
vesicle mediated transport GO:0016192 371 0.030
regulation of vasculature development GO:1901342 97 0.030
positive regulation of neural precursor cell proliferation GO:2000179 2 0.030
endocrine pancreas development GO:0031018 11 0.030
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.030
protein localization to organelle GO:0033365 280 0.030
regulation of cytokine production GO:0001817 232 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.030
regulation of peptide hormone secretion GO:0090276 41 0.030
Mouse
cellular lipid catabolic process GO:0044242 65 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
cytokine production GO:0001816 247 0.029
muscle organ development GO:0007517 56 0.029
canonical wnt signaling pathway GO:0060070 116 0.029
secondary heart field specification GO:0003139 2 0.029
negative regulation of immune system process GO:0002683 136 0.029
somitogenesis GO:0001756 2 0.029
formation of primary germ layer GO:0001704 42 0.029
regulation of neural precursor cell proliferation GO:2000177 4 0.029
viral process GO:0016032 146 0.029
phosphatidylinositol mediated signaling GO:0048015 55 0.029
regulation of transcription involved in cell fate commitment GO:0060850 6 0.029
regulation of peptidase activity GO:0052547 180 0.029
cellular amide metabolic process GO:0043603 69 0.029
regulation of heart morphogenesis GO:2000826 4 0.029
response to estrogen GO:0043627 47 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.028
erythrocyte homeostasis GO:0034101 31 0.028
hard palate development GO:0060022 1 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
hindlimb morphogenesis GO:0035137 2 0.028
appendage morphogenesis GO:0035107 16 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.028
regulation of canonical wnt signaling pathway GO:0060828 88 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
mesonephros development GO:0001823 17 0.027
muscle structure development GO:0061061 98 0.027
muscle organ morphogenesis GO:0048644 19 0.027
regulation of organ formation GO:0003156 4 0.027
actin filament based movement GO:0030048 17 0.027
motor neuron axon guidance GO:0008045 2 0.027
axis elongation GO:0003401 4 0.027
myeloid cell homeostasis GO:0002262 34 0.027
apoptotic process involved in morphogenesis GO:0060561 3 0.026
interspecies interaction between organisms GO:0044419 156 0.026
outflow tract septum morphogenesis GO:0003148 4 0.026
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 2 0.026
neural tube patterning GO:0021532 2 0.026
response to oxidative stress GO:0006979 121 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
intracellular receptor signaling pathway GO:0030522 104 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
activation of mapk activity GO:0000187 45 0.026
positive regulation of protein complex assembly GO:0031334 86 0.026
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.026
regulation of muscle cell differentiation GO:0051147 31 0.026
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.025
neuromuscular junction development GO:0007528 3 0.025
muscle tissue morphogenesis GO:0060415 19 0.025
metal ion transport GO:0030001 272 0.025
odontogenesis GO:0042476 25 0.025
regulation of lipid biosynthetic process GO:0046890 47 0.025
cellular response to cytokine stimulus GO:0071345 181 0.025
response to cytokine GO:0034097 232 0.024
regulation of angiogenesis GO:0045765 92 0.024
renal system process GO:0003014 25 0.024
cell growth GO:0016049 160 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
response to hypoxia GO:0001666 96 0.024
carbohydrate homeostasis GO:0033500 31 0.023
Mouse
regulation of glial cell differentiation GO:0045685 3 0.023
branching morphogenesis of an epithelial tube GO:0048754 19 0.023
muscle cell differentiation GO:0042692 63 0.023
cell aging GO:0007569 52 0.023
regulation of oxidoreductase activity GO:0051341 43 0.023
hematopoietic progenitor cell differentiation GO:0002244 38 0.023
regulation of osteoblast differentiation GO:0045667 38 0.023
monosaccharide metabolic process GO:0005996 74 0.023
Mouse
positive regulation of fatty acid metabolic process GO:0045923 11 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
regulation of membrane potential GO:0042391 95 0.023
rhythmic behavior GO:0007622 2 0.023
epithelial tube morphogenesis GO:0060562 38 0.023
regulation of proteolysis GO:0030162 293 0.022
visual behavior GO:0007632 2 0.022
renal tubule development GO:0061326 19 0.022
multi organism cellular process GO:0044764 156 0.022
urogenital system development GO:0001655 65 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.022
regulation of cell projection organization GO:0031344 107 0.022

PDX1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.412
acquired metabolic disease DOID:0060158 58 0.263
maturity onset diabetes of the young DOID:0050524 10 0.074
diabetes mellitus DOID:9351 31 0.073
carbohydrate metabolism disease DOID:0050013 32 0.073
glucose metabolism disease DOID:4194 32 0.073
type 2 diabetes mellitus DOID:9352 28 0.050
sensory system disease DOID:0050155 203 0.044
nervous system disease DOID:863 431 0.044
disease of cellular proliferation DOID:14566 174 0.031
cancer DOID:162 167 0.031