Homo sapiens

0 known processes

GJA8

gap junction protein, alpha 8, 50kDa

(Aliases: CZP1,CAE1,CX50,CAE,MP70)

GJA8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.105
cellular ketone metabolic process GO:0042180 80 0.089
regulation of cellular ketone metabolic process GO:0010565 50 0.087
regulation of cellular amine metabolic process GO:0033238 11 0.087
cellular amino acid metabolic process GO:0006520 116 0.086
amine metabolic process GO:0009308 44 0.086
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
post embryonic development GO:0009791 2 0.054
system process GO:0003008 349 0.050
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
regulation of cell differentiation GO:0045595 393 0.041
negative regulation of apoptotic process GO:0043066 316 0.039
cyclic nucleotide metabolic process GO:0009187 82 0.039
regulation of cell cycle GO:0051726 393 0.037
signal transduction by phosphorylation GO:0023014 297 0.036
epithelial cell differentiation GO:0030855 141 0.035
small molecule biosynthetic process GO:0044283 157 0.035
positive regulation of cell proliferation GO:0008284 301 0.035
vasculature development GO:0001944 181 0.035
Human
regulation of cellular component movement GO:0051270 334 0.034
Human
multicellular organismal aging GO:0010259 3 0.033
regulation of cell motility GO:2000145 299 0.032
positive regulation of hydrolase activity GO:0051345 331 0.031
alcohol metabolic process GO:0006066 114 0.031
cell adhesion GO:0007155 325 0.030
negative regulation of cell death GO:0060548 345 0.030
positive regulation of phosphorylation GO:0042327 394 0.030
cytoplasmic transport GO:0016482 379 0.029
response to abiotic stimulus GO:0009628 336 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
cell growth GO:0016049 160 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
regulation of protein transport GO:0051223 213 0.028
small gtpase mediated signal transduction GO:0007264 78 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
determination of adult lifespan GO:0008340 2 0.027
negative regulation of cell differentiation GO:0045596 171 0.027
protein localization to organelle GO:0033365 280 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
immune response GO:0006955 307 0.027
negative regulation of developmental process GO:0051093 247 0.027
regulation of proteolysis GO:0030162 293 0.027
lipid metabolic process GO:0006629 381 0.027
anion transport GO:0006820 161 0.027
mitotic cell cycle GO:0000278 326 0.027
cardiovascular system development GO:0072358 262 0.026
Human
cellular response to growth factor stimulus GO:0071363 197 0.026
positive regulation of programmed cell death GO:0043068 249 0.026
regulation of locomotion GO:0040012 329 0.026
segmentation GO:0035282 4 0.026
mapk cascade GO:0000165 288 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
positive regulation of aldosterone metabolic process GO:0032346 2 0.025
regulation of growth GO:0040008 165 0.025
chemical homeostasis GO:0048878 306 0.025
Human
positive regulation of cell death GO:0010942 263 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
Human
positive regulation of apoptotic process GO:0043065 246 0.024
regulation of protein localization GO:0032880 296 0.024
biological adhesion GO:0022610 331 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
cell morphogenesis GO:0000902 296 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
negative regulation of cell cycle GO:0045786 193 0.023
neurological system process GO:0050877 163 0.023
intracellular protein transport GO:0006886 270 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
apoptotic signaling pathway GO:0097190 268 0.023
organic hydroxy compound metabolic process GO:1901615 147 0.022
regulation of cell growth GO:0001558 135 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
protein oligomerization GO:0051259 173 0.022
female gamete generation GO:0007292 2 0.022
regulation of cellular response to stress GO:0080135 244 0.022
regulation of cell cycle process GO:0010564 266 0.022
response to oxygen containing compound GO:1901700 369 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
ion homeostasis GO:0050801 230 0.021
Human
regulation of cytokine production GO:0001817 232 0.021
transmembrane transport GO:0055085 399 0.021
Human
cellular macromolecule catabolic process GO:0044265 380 0.021
positive regulation of immune system process GO:0002684 283 0.021
locomotory behavior GO:0007626 1 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
growth GO:0040007 202 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
cell fate determination GO:0001709 3 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
regulation of secretion by cell GO:1903530 177 0.020
cell cycle phase transition GO:0044770 173 0.020
g protein coupled receptor signaling pathway GO:0007186 207 0.020
regeneration GO:0031099 4 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
purine containing compound catabolic process GO:0072523 411 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
secretion GO:0046903 254 0.019
cellular component morphogenesis GO:0032989 314 0.019
regulation of secretion GO:0051046 194 0.019
protein catabolic process GO:0030163 325 0.019
regulation of transferase activity GO:0051338 355 0.019
circulatory system development GO:0072359 262 0.019
Human
negative regulation of transport GO:0051051 176 0.018
limbic system development GO:0021761 3 0.018
epithelium development GO:0060429 227 0.018
response to growth factor GO:0070848 205 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
ras protein signal transduction GO:0007265 73 0.018
actin mediated cell contraction GO:0070252 12 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
regulation of testosterone biosynthetic process GO:2000224 2 0.018
positive regulation of cytokine production GO:0001819 167 0.018
regulation of cell migration GO:0030334 289 0.018
blood vessel development GO:0001568 172 0.018
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.018
chromatin organization GO:0006325 351 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
single organism cellular localization GO:1902580 332 0.018
response to external biotic stimulus GO:0043207 261 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
spermatid differentiation GO:0048515 4 0.017
defense response GO:0006952 315 0.017
cytokine production GO:0001816 247 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
protein maturation GO:0051604 233 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
cell projection organization GO:0030030 252 0.017
mitotic cell cycle process GO:1903047 286 0.017
regulation of mapk cascade GO:0043408 262 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
cell activation GO:0001775 213 0.017
negative regulation of protein modification process GO:0031400 200 0.017
actin filament based process GO:0030029 224 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
cellular homeostasis GO:0019725 196 0.017
oogenesis GO:0048477 2 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
sodium independent organic anion transport GO:0043252 2 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
hair follicle morphogenesis GO:0031069 2 0.016
negative regulation of growth GO:0045926 97 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
adult locomotory behavior GO:0008344 1 0.016
positive regulation of organelle organization GO:0010638 195 0.016
oxidation reduction process GO:0055114 396 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
dephosphorylation GO:0016311 209 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
detection of stimulus GO:0051606 85 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
nuclear transport GO:0051169 179 0.016
leukocyte activation GO:0045321 164 0.016
metal ion homeostasis GO:0055065 169 0.016
lymphocyte activation GO:0046649 133 0.016
positive regulation of developmental process GO:0051094 314 0.016
nitrogen compound transport GO:0071705 191 0.016
regulation of hormone levels GO:0010817 125 0.016
cellular protein catabolic process GO:0044257 261 0.016
immune system development GO:0002520 195 0.016
actin filament based movement GO:0030048 17 0.016
regulation of peptidase activity GO:0052547 180 0.016
chromatin modification GO:0016568 298 0.016
response to transforming growth factor beta GO:0071559 94 0.016
nervous system development GO:0007399 293 0.016
positive regulation of secretion by cell GO:1903532 108 0.015
regulation of kinase activity GO:0043549 314 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
ribose phosphate biosynthetic process GO:0046390 82 0.015
head development GO:0060322 108 0.015
secretion by cell GO:0032940 226 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
protein targeting GO:0006605 187 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
compound eye development GO:0048749 1 0.015
angiogenesis GO:0001525 147 0.015
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.015
regulation of intracellular transport GO:0032386 195 0.015
purine containing compound biosynthetic process GO:0072522 88 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
sensory perception GO:0007600 103 0.015
regulation of cell development GO:0060284 161 0.015
innate immune response GO:0045087 178 0.015
lipid biosynthetic process GO:0008610 177 0.015
blastoderm segmentation GO:0007350 2 0.015
negative regulation of cell migration GO:0030336 102 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
response to other organism GO:0051707 261 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
cell proliferation in forebrain GO:0021846 1 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
sensory perception of smell GO:0007608 2 0.014
single organism membrane organization GO:0044802 268 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
response to cytokine GO:0034097 232 0.014
heart development GO:0007507 95 0.014
Human
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of protein transport GO:0051222 135 0.014
taxis GO:0042330 157 0.014
spermatid development GO:0007286 4 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
stem cell differentiation GO:0048863 93 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
positive regulation of secretion GO:0051047 116 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
cell development GO:0048468 328 0.014
protein ubiquitination GO:0016567 314 0.014
ion transmembrane transport GO:0034220 338 0.014
hindbrain development GO:0030902 3 0.014
membrane organization GO:0061024 292 0.014
rna processing GO:0006396 255 0.014
positive regulation of cell migration GO:0030335 172 0.014
positive regulation of hormone biosynthetic process GO:0046886 4 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
single organismal cell cell adhesion GO:0016337 148 0.014
nucleotide biosynthetic process GO:0009165 109 0.014
neuromuscular junction development GO:0007528 3 0.014
protein acylation GO:0043543 138 0.014
epidermis morphogenesis GO:0048730 3 0.013
nucleotide catabolic process GO:0009166 408 0.013
nucleoside catabolic process GO:0009164 408 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
negative regulation of immune system process GO:0002683 136 0.013
sex determination GO:0007530 3 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
protein processing GO:0016485 226 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
protein localization to nucleus GO:0034504 136 0.013
regulation of protein catabolic process GO:0042176 155 0.013
prostate gland development GO:0030850 3 0.013
negative regulation of cell growth GO:0030308 83 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
organophosphate catabolic process GO:0046434 430 0.013
blood circulation GO:0008015 113 0.013
Human
neurogenesis GO:0022008 169 0.013
metencephalon development GO:0022037 2 0.013
organelle assembly GO:0070925 176 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
cerebellum development GO:0021549 2 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
hemopoiesis GO:0030097 180 0.013
regulation of response to external stimulus GO:0032101 222 0.013
cardiac muscle contraction GO:0060048 34 0.013
Human
anterior posterior axis specification GO:0009948 2 0.013
positive regulation of proteolysis GO:0045862 142 0.013
response to lipid GO:0033993 206 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of immune response GO:0050776 201 0.012
peripheral nervous system development GO:0007422 2 0.012
microtubule based process GO:0007017 210 0.012
vesicle mediated transport GO:0016192 371 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
cation homeostasis GO:0055080 189 0.012
myeloid cell differentiation GO:0030099 117 0.012
regulation of male gonad development GO:2000018 4 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
positive regulation of immune response GO:0050778 159 0.012
oocyte differentiation GO:0009994 2 0.012
alcohol biosynthetic process GO:0046165 52 0.012
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.012
hindlimb morphogenesis GO:0035137 2 0.012
maintenance of location GO:0051235 112 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
regulation of protein processing GO:0070613 150 0.012
nerve development GO:0021675 4 0.012
myoblast fusion GO:0007520 1 0.012
positive regulation of transport GO:0051050 336 0.012
regulation of system process GO:0044057 101 0.012
Human
regulation of synaptic plasticity GO:0048167 3 0.012
positive regulation of cell adhesion GO:0045785 84 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
cellular response to external stimulus GO:0071496 111 0.012
tissue regeneration GO:0042246 3 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
associative learning GO:0008306 1 0.012
cellular cation homeostasis GO:0030003 163 0.012
cellular lipid metabolic process GO:0044255 303 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of metal ion transport GO:0010959 120 0.012
single organism cell adhesion GO:0098602 179 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
negative regulation of locomotion GO:0040013 118 0.012
protein localization to membrane GO:0072657 160 0.012
embryo development GO:0009790 123 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
sensory perception of pain GO:0019233 4 0.012
regulation of cell adhesion GO:0030155 166 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.011
response to radiation GO:0009314 151 0.011
immune effector process GO:0002252 159 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
cation transport GO:0006812 331 0.011
cofactor metabolic process GO:0051186 87 0.011
cyclic purine nucleotide metabolic process GO:0052652 60 0.011
cell division GO:0051301 168 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
negative regulation of proteolysis GO:0045861 132 0.011
regulation of cell cell adhesion GO:0022407 57 0.011
cell projection morphogenesis GO:0048858 129 0.011
cell part morphogenesis GO:0032990 137 0.011
regulation of transporter activity GO:0032409 82 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
histone modification GO:0016570 251 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
cellular response to lipid GO:0071396 127 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
sequestering of calcium ion GO:0051208 17 0.011
negative regulation of protein processing GO:0010955 142 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of protein kinase activity GO:0045859 289 0.011
reproductive process GO:0022414 106 0.011
central nervous system development GO:0007417 123 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
skeletal system development GO:0001501 79 0.011
plasma membrane organization GO:0007009 115 0.011
regulation of protein stability GO:0031647 87 0.011
generation of neurons GO:0048699 152 0.011
negative regulation of protein maturation GO:1903318 142 0.011
wnt signaling pathway GO:0016055 156 0.011
actin cytoskeleton organization GO:0030036 207 0.011
forebrain regionalization GO:0021871 3 0.011
negative regulation of transferase activity GO:0051348 124 0.011
epithelial cell proliferation GO:0050673 128 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
forebrain neuron differentiation GO:0021879 3 0.011
regulation of transmembrane transport GO:0034762 139 0.011
response to fungus GO:0009620 4 0.011
oocyte development GO:0048599 1 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
negative regulation of cell motility GO:2000146 104 0.010
glycosyl compound catabolic process GO:1901658 413 0.010
cytokine secretion GO:0050663 64 0.010
endocytosis GO:0006897 159 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
regulation of cell projection organization GO:0031344 107 0.010
regulation of dna metabolic process GO:0051052 153 0.010
brain development GO:0007420 97 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
regulation of anatomical structure size GO:0090066 101 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.010
mitochondrion organization GO:0007005 156 0.010
negative regulation of gliogenesis GO:0014014 3 0.010
response to axon injury GO:0048678 1 0.010
organic acid transport GO:0015849 65 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
regulation of epithelial cell migration GO:0010632 93 0.010

GJA8 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.068
Human
nervous system disease DOID:863 431 0.068
Human
eye and adnexa disease DOID:1492 150 0.039
retinal disease DOID:5679 118 0.037
eye disease DOID:5614 149 0.037
disease of metabolism DOID:0014667 295 0.027
musculoskeletal system disease DOID:17 223 0.026
night blindness DOID:8499 10 0.025
immune system disease DOID:2914 155 0.019
Human
retinal degeneration DOID:8466 89 0.016
disease of cellular proliferation DOID:14566 174 0.014
bone disease DOID:0080001 88 0.013
connective tissue disease DOID:65 109 0.013
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.012
central nervous system disease DOID:331 186 0.012
Human
inherited metabolic disorder DOID:655 242 0.011