Homo sapiens

67 known processes

BIK

BCL2-interacting killer (apoptosis-inducing)

(Aliases: NBK,BIP1,BP4)

BIK biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein oligomerization GO:0032459 26 0.709
positive regulation of apoptotic signaling pathway GO:2001235 70 0.628
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.613
positive regulation of protein oligomerization GO:0032461 17 0.460
regulation of apoptotic signaling pathway GO:2001233 175 0.434
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 2 0.433
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.386
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.341
apoptotic mitochondrial changes GO:0008637 57 0.339
regulation of mitochondrion organization GO:0010821 54 0.317
neural tube patterning GO:0021532 2 0.314
cellular ketone metabolic process GO:0042180 80 0.307
cd8 positive alpha beta t cell differentiation GO:0043374 1 0.284
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 6 0.256
regulation of proteolysis GO:0030162 293 0.255
mitochondrial outer membrane permeabilization GO:0097345 15 0.244
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.244
protein homooligomerization GO:0051260 100 0.242
negative regulation of programmed cell death GO:0043069 321 0.242
regulation of peptidase activity GO:0052547 180 0.240
positive regulation of cellular component organization GO:0051130 376 0.234
regulation of cellular component biogenesis GO:0044087 281 0.231
positive regulation of cell death GO:0010942 263 0.230
post embryonic development GO:0009791 2 0.230
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.223
apoptotic process involved in morphogenesis GO:0060561 3 0.216
apoptotic signaling pathway GO:0097190 268 0.210
positive regulation of cellular component biogenesis GO:0044089 158 0.209
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.202
mitochondrial membrane organization GO:0007006 40 0.202
cellular amine metabolic process GO:0044106 41 0.197
positive regulation of hydrolase activity GO:0051345 331 0.193
positive regulation of apoptotic process GO:0043065 246 0.190
positive regulation of programmed cell death GO:0043068 249 0.185
zymogen activation GO:0031638 70 0.184
regulation of cysteine type endopeptidase activity GO:2000116 127 0.182
negative regulation of apoptotic process GO:0043066 316 0.178
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.176
release of cytochrome c from mitochondria GO:0001836 35 0.176
mitochondrial transport GO:0006839 60 0.175
regulation of membrane permeability GO:0090559 25 0.174
cellular cation homeostasis GO:0030003 163 0.174
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.167
cellular amino acid metabolic process GO:0006520 116 0.166
regulation of mitochondrial membrane permeability GO:0046902 25 0.166
negative regulation of calcium ion transport into cytosol GO:0010523 3 0.164
membrane organization GO:0061024 292 0.162
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.158
fear response GO:0042596 0 0.158
protein processing GO:0016485 226 0.156
regulation of endopeptidase activity GO:0052548 170 0.152
regulation of cellular amine metabolic process GO:0033238 11 0.150
behavioral defense response GO:0002209 0 0.135
developmental programmed cell death GO:0010623 3 0.134
protein oligomerization GO:0051259 173 0.134
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.134
positive regulation of proteolysis GO:0045862 142 0.128
positive regulation of protein homooligomerization GO:0032464 7 0.122
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 2 0.121
cellular response to hypoxia GO:0071456 51 0.120
regulation of cellular amino acid metabolic process GO:0006521 6 0.117
extrinsic apoptotic signaling pathway GO:0097191 119 0.117
regulation of protein complex assembly GO:0043254 147 0.117
sequestering of calcium ion GO:0051208 17 0.116
regulation of cellular ketone metabolic process GO:0010565 50 0.116
positive regulation of endoplasmic reticulum unfolded protein response GO:1900103 4 0.115
cellular homeostasis GO:0019725 196 0.115
protein insertion into mitochondrial membrane GO:0051204 3 0.115
positive regulation of transport GO:0051050 336 0.112
calcium ion transport GO:0006816 147 0.111
amine metabolic process GO:0009308 44 0.109
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.107
pigment granule organization GO:0048753 7 0.107
defense response to other organism GO:0098542 129 0.105
intrinsic apoptotic signaling pathway GO:0097193 127 0.103
single organism membrane organization GO:0044802 268 0.101
regulation of cellular component movement GO:0051270 334 0.101
positive regulation of organelle organization GO:0010638 195 0.100
protein maturation GO:0051604 233 0.100
positive regulation of peptidase activity GO:0010952 88 0.099
hair follicle morphogenesis GO:0031069 2 0.099
cation homeostasis GO:0055080 189 0.099
cellular response to external stimulus GO:0071496 111 0.098
positive regulation of endopeptidase activity GO:0010950 84 0.097
suppression by virus of host apoptotic process GO:0019050 1 0.096
response to other organism GO:0051707 261 0.095
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.094
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.094
establishment of protein localization to mitochondrion GO:0072655 22 0.093
immune response GO:0006955 307 0.093
defense response GO:0006952 315 0.092
response to abiotic stimulus GO:0009628 336 0.089
negative regulation of apoptotic signaling pathway GO:2001234 97 0.089
cellular component morphogenesis GO:0032989 314 0.089
response to hypoxia GO:0001666 96 0.085
response to radiation GO:0009314 151 0.084
growth GO:0040007 202 0.084
reactive oxygen species metabolic process GO:0072593 75 0.083
cellular component disassembly GO:0022411 92 0.082
positive regulation of mitochondrion organization GO:0010822 30 0.081
cell adhesion GO:0007155 325 0.079
response to organic cyclic compound GO:0014070 204 0.078
negative regulation of cell death GO:0060548 345 0.076
cellular calcium ion homeostasis GO:0006874 117 0.075
activation of cysteine type endopeptidase activity GO:0097202 57 0.075
cellular response to endogenous stimulus GO:0071495 336 0.074
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.074
positive regulation of catabolic process GO:0009896 310 0.073
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.071
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.071
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.071
mitochondrion organization GO:0007005 156 0.070
anatomical structure formation involved in morphogenesis GO:0048646 284 0.070
apoptotic process in bone marrow GO:0071839 1 0.070
response to external biotic stimulus GO:0043207 261 0.069
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 2 0.068
small gtpase mediated signal transduction GO:0007264 78 0.068
divalent inorganic cation homeostasis GO:0072507 136 0.067
positive regulation of cellular amine metabolic process GO:0033240 7 0.067
modulation of apoptotic process in other organism GO:0044532 1 0.066
regulation of protein localization GO:0032880 296 0.065
single organism cellular localization GO:1902580 332 0.064
hematopoietic or lymphoid organ development GO:0048534 186 0.064
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.064
positive regulation of cellular catabolic process GO:0031331 284 0.063
regulation of membrane potential GO:0042391 95 0.063
regulation of cellular response to stress GO:0080135 244 0.063
modulation by organism of apoptotic process in other organism involved in symbiotic interaction GO:0052433 1 0.062
response to virus GO:0009615 126 0.062
protein localization to organelle GO:0033365 280 0.062
protein catabolic process GO:0030163 325 0.061
positive regulation of immune system process GO:0002684 283 0.061
organ morphogenesis GO:0009887 147 0.061
regulation of cell cycle process GO:0010564 266 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
modulation by symbiont of host cellular process GO:0044068 3 0.061
modulation by symbiont of host programmed cell death GO:0052040 1 0.060
positive regulation of protein complex assembly GO:0031334 86 0.060
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.060
defense response to virus GO:0051607 71 0.059
modulation of programmed cell death in other organism involved in symbiotic interaction GO:0052248 1 0.059
cellular response to dna damage stimulus GO:0006974 379 0.059
epithelium development GO:0060429 227 0.058
negative regulation of cell proliferation GO:0008285 228 0.058
ribonucleoside triphosphate catabolic process GO:0009203 391 0.058
regulation of establishment of protein localization GO:0070201 242 0.058
neuron death in response to oxidative stress GO:0036475 9 0.058
modulation by symbiont of host apoptotic process GO:0052150 1 0.057
post embryonic organ development GO:0048569 1 0.057
cellular macromolecule catabolic process GO:0044265 380 0.056
epidermis morphogenesis GO:0048730 3 0.055
glycosyl compound catabolic process GO:1901658 413 0.055
metal ion transport GO:0030001 272 0.055
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.055
negative regulation of catalytic activity GO:0043086 335 0.055
cell substrate adhesion GO:0031589 132 0.055
modulation of programmed cell death in other organism GO:0044531 1 0.055
single organism carbohydrate metabolic process GO:0044723 193 0.055
establishment of protein localization to membrane GO:0090150 121 0.054
ion homeostasis GO:0050801 230 0.054
positive regulation of fibroblast apoptotic process GO:2000271 6 0.053
negative regulation of cellular protein metabolic process GO:0032269 353 0.053
response to hormone GO:0009725 175 0.053
epithelial cell proliferation GO:0050673 128 0.053
sequestering of metal ion GO:0051238 24 0.053
patterning of blood vessels GO:0001569 2 0.053
multicellular organismal response to stress GO:0033555 1 0.052
activation of immune response GO:0002253 114 0.051
response to biotic stimulus GO:0009607 276 0.051
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.051
protein localization to membrane GO:0072657 160 0.051
immune effector process GO:0002252 159 0.050
cellular response to nitrogen compound GO:1901699 144 0.050
positive regulation of oxidative stress induced cell death GO:1903209 5 0.050
divalent metal ion transport GO:0070838 152 0.050
response to decreased oxygen levels GO:0036293 96 0.049
ras protein signal transduction GO:0007265 73 0.049
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.049
cation transport GO:0006812 331 0.049
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 1 0.048
calcium ion homeostasis GO:0055074 122 0.048
mitotic cell cycle phase transition GO:0044772 162 0.048
nervous system development GO:0007399 293 0.048
cell type specific apoptotic process GO:0097285 125 0.048
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.048
multicellular organismal aging GO:0010259 3 0.047
positive regulation of execution phase of apoptosis GO:1900119 5 0.047
immune response regulating signaling pathway GO:0002764 97 0.047
hypothalamus development GO:0021854 1 0.047
protein localization to plasma membrane GO:0072659 93 0.047
regeneration GO:0031099 4 0.046
response to oxygen levels GO:0070482 100 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
metal ion homeostasis GO:0055065 169 0.046
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.046
lymphocyte homeostasis GO:0002260 4 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
mammary gland morphogenesis GO:0060443 2 0.045
regulation of cell differentiation GO:0045595 393 0.044
reactive nitrogen species metabolic process GO:2001057 3 0.044
viral process GO:0016032 146 0.044
positive regulation of apoptotic process involved in morphogenesis GO:1902339 1 0.044
response to axon injury GO:0048678 1 0.044
response to oxygen containing compound GO:1901700 369 0.044
regulation of anatomical structure morphogenesis GO:0022603 286 0.043
cellular metal ion homeostasis GO:0006875 146 0.043
regulation of protein kinase activity GO:0045859 289 0.042
biological adhesion GO:0022610 331 0.042
divalent inorganic cation transport GO:0072511 158 0.042
execution phase of apoptosis GO:0097194 32 0.041
cardiovascular system development GO:0072358 262 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.041
oogenesis GO:0048477 2 0.040
transmembrane transport GO:0055085 399 0.040
cell development GO:0048468 328 0.040
female gamete generation GO:0007292 2 0.040
regulation of immune response GO:0050776 201 0.040
response to metal ion GO:0010038 84 0.040
tissue morphogenesis GO:0048729 96 0.039
multi organism cellular process GO:0044764 156 0.039
positive regulation of muscle cell differentiation GO:0051149 15 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.039
guanosine containing compound catabolic process GO:1901069 239 0.039
tube morphogenesis GO:0035239 95 0.038
regulation of epithelial cell proliferation GO:0050678 113 0.038
inorganic cation transmembrane transport GO:0098662 194 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901028 9 0.037
t cell homeostasis GO:0043029 3 0.037
negative regulation of cellular amine metabolic process GO:0033239 3 0.037
lytic vacuole organization GO:0080171 24 0.037
single organism cell adhesion GO:0098602 179 0.037
glycoprotein metabolic process GO:0009100 110 0.037
single organism membrane fusion GO:0044801 37 0.036
response to lipid GO:0033993 206 0.036
peptidyl serine modification GO:0018209 106 0.036
regulation of apoptotic dna fragmentation GO:1902510 3 0.036
protein polyubiquitination GO:0000209 110 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
cellular lipid metabolic process GO:0044255 303 0.036
interspecies interaction between organisms GO:0044419 156 0.036
response to nitrogen compound GO:1901698 184 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
cellular ion homeostasis GO:0006873 168 0.035
cytokine production GO:0001816 247 0.035
negative regulation of organelle organization GO:0010639 126 0.035
actin filament based process GO:0030029 224 0.035
protein ubiquitination GO:0016567 314 0.035
modulation by virus of host morphology or physiology GO:0019048 10 0.034
response to electrical stimulus GO:0051602 1 0.034
response to ionizing radiation GO:0010212 65 0.034
hindbrain development GO:0030902 3 0.034
response to endoplasmic reticulum stress GO:0034976 49 0.034
thymus development GO:0048538 3 0.034
regulation of response to dna damage stimulus GO:2001020 94 0.034
modulation by virus of host process GO:0019054 2 0.033
axon regeneration GO:0031103 1 0.033
lipid metabolic process GO:0006629 381 0.033
regulation of cell motility GO:2000145 299 0.033
regulation of execution phase of apoptosis GO:1900117 11 0.033
tube development GO:0035295 125 0.033
ossification GO:0001503 121 0.033
dephosphorylation GO:0016311 209 0.033
positive regulation of developmental pigmentation GO:0048087 2 0.032
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.032
immune response activating signal transduction GO:0002757 90 0.032
regulation of cellular ph reduction GO:0032847 1 0.032
response to uv GO:0009411 73 0.032
response to extracellular stimulus GO:0009991 85 0.032
memory GO:0007613 3 0.032
response to estrogen GO:0043627 47 0.032
plasma membrane organization GO:0007009 115 0.032
regulation of killing of cells of other organism GO:0051709 4 0.032
regulation of calcium ion transport into cytosol GO:0010522 33 0.031
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.031
neuron projection regeneration GO:0031102 1 0.031
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.031
regulation of sequestering of calcium ion GO:0051282 41 0.031
locomotory behavior GO:0007626 1 0.031
protein localization to mitochondrion GO:0070585 25 0.030
regulation of cell maturation GO:1903429 3 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
positive regulation of cytokine production GO:0001819 167 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
lung alveolus development GO:0048286 4 0.030
regulation of mitotic cell cycle phase transition GO:1901990 118 0.030
negative regulation of protein modification process GO:0031400 200 0.030
cellular response to extracellular stimulus GO:0031668 72 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.030
brain morphogenesis GO:0048854 1 0.030
negative regulation of cellular component organization GO:0051129 235 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
modification of morphology or physiology of other organism GO:0035821 43 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.029
segmentation GO:0035282 4 0.029
posttranscriptional regulation of gene expression GO:0010608 213 0.029
negative regulation of cell cycle GO:0045786 193 0.029
release of sequestered calcium ion into cytosol GO:0051209 41 0.029
lymphocyte activation GO:0046649 133 0.029
regulation of cell cycle GO:0051726 393 0.029
purine nucleoside catabolic process GO:0006152 398 0.029
regulation of cell migration GO:0030334 289 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
thymocyte apoptotic process GO:0070242 2 0.028
cellular response to organonitrogen compound GO:0071417 124 0.028
cellular response to decreased oxygen levels GO:0036294 51 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 0.028
photoreceptor cell differentiation GO:0046530 2 0.028
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.027
regulation of developmental pigmentation GO:0048070 2 0.027
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
cell morphogenesis GO:0000902 296 0.027
cellular response to organic cyclic compound GO:0071407 127 0.027
negative regulation of locomotion GO:0040013 118 0.027
ion transmembrane transport GO:0034220 338 0.027
cellular response to nicotine GO:0071316 4 0.027
cytoplasmic transport GO:0016482 379 0.027
rho protein signal transduction GO:0007266 26 0.027
carbohydrate metabolic process GO:0005975 207 0.027
regulation of ion homeostasis GO:2000021 73 0.027
cellular response to starvation GO:0009267 58 0.027
developmental pigmentation GO:0048066 12 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
head development GO:0060322 108 0.026
receptor metabolic process GO:0043112 81 0.026
bmp signaling pathway GO:0030509 49 0.026
oocyte differentiation GO:0009994 2 0.026
morphogenesis of embryonic epithelium GO:0016331 4 0.026
positive regulation of response to oxidative stress GO:1902884 7 0.026
regulation of intracellular transport GO:0032386 195 0.026
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.026
synaptic vesicle endocytosis GO:0048488 2 0.026
positive regulation of intracellular transport GO:0032388 104 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
negative regulation of protein phosphorylation GO:0001933 140 0.026
regulation of synaptic plasticity GO:0048167 3 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.025
regulation of cytoskeleton organization GO:0051493 177 0.025
somitogenesis GO:0001756 2 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
positive regulation of immune response GO:0050778 159 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
response to wounding GO:0009611 168 0.025
collateral sprouting GO:0048668 2 0.025
positive regulation of killing of cells of other organism GO:0051712 4 0.025
central nervous system development GO:0007417 123 0.025
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.025
circulatory system development GO:0072359 262 0.025
regulation of multi organism process GO:0043900 157 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
negative regulation of developmental process GO:0051093 247 0.025
response to salt stress GO:0009651 3 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
cellular protein catabolic process GO:0044257 261 0.025
regulation of cell development GO:0060284 161 0.024
blood vessel development GO:0001568 172 0.024
cytosolic calcium ion homeostasis GO:0051480 89 0.024
regulation of protein localization to plasma membrane GO:1903076 40 0.024
actin filament organization GO:0007015 128 0.024
spermatid differentiation GO:0048515 4 0.024
negative regulation of cell cycle process GO:0010948 121 0.024
regulation of growth GO:0040008 165 0.024
response to organonitrogen compound GO:0010243 156 0.024
response to steroid hormone GO:0048545 80 0.024
regulation of kinase activity GO:0043549 314 0.023
negative regulation of phosphatase activity GO:0010923 61 0.023
cellular protein complex assembly GO:0043623 188 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
vesicle mediated transport GO:0016192 371 0.023
cellular carbohydrate metabolic process GO:0044262 84 0.023
neuron apoptotic process GO:0051402 39 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
hair cycle GO:0042633 28 0.023
determination of adult lifespan GO:0008340 2 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
mitotic cell cycle GO:0000278 326 0.022
metencephalon development GO:0022037 2 0.022
regulation of protein binding GO:0043393 66 0.022
epidermis development GO:0008544 59 0.022
negative regulation of transferase activity GO:0051348 124 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
maintenance of location GO:0051235 112 0.022
response to inorganic substance GO:0010035 127 0.022
dna catabolic process endonucleolytic GO:0000737 37 0.022
embryonic morphogenesis GO:0048598 85 0.022
b cell homeostasis GO:0001782 1 0.021
regulation of protein homooligomerization GO:0032462 11 0.021
renal system development GO:0072001 63 0.021
oocyte development GO:0048599 1 0.021
cellular response to uv GO:0034644 32 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
endosomal transport GO:0016197 129 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
cellular response to nutrient levels GO:0031669 69 0.021
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.021
positive regulation of lymphocyte proliferation GO:0050671 46 0.021
gland development GO:0048732 48 0.021
positive regulation of myotube differentiation GO:0010831 3 0.021
mating GO:0007618 1 0.021
glial cell migration GO:0008347 4 0.021
purine containing compound catabolic process GO:0072523 411 0.021
nitrogen compound transport GO:0071705 191 0.021
regulation of cell adhesion GO:0030155 166 0.021
embryo development GO:0009790 123 0.021
response to alcohol GO:0097305 64 0.021
negative regulation of cell migration GO:0030336 102 0.021
regulation of reactive oxygen species metabolic process GO:2000377 41 0.021
angiogenesis GO:0001525 147 0.020
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.020
positive regulation of epithelial cell proliferation GO:0050679 65 0.020
gtp catabolic process GO:0006184 237 0.020
nucleoside catabolic process GO:0009164 408 0.020
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.020
necrotic cell death GO:0070265 21 0.020
cellular response to oxygen levels GO:0071453 55 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
compound eye development GO:0048749 1 0.020
positive regulation of secretion GO:0051047 116 0.020
vacuole organization GO:0007033 44 0.020
organelle fusion GO:0048284 36 0.020
inflammatory response GO:0006954 79 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
embryonic placenta development GO:0001892 1 0.020
cell activation GO:0001775 213 0.020
mitotic cell cycle process GO:1903047 286 0.020
copulation GO:0007620 1 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
response to starvation GO:0042594 59 0.019
endomembrane system organization GO:0010256 196 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.019
response to oxidative stress GO:0006979 121 0.019
intracellular protein transport GO:0006886 270 0.019
beta amyloid metabolic process GO:0050435 12 0.019
protein o linked glycosylation via serine GO:0018242 3 0.019
melanin metabolic process GO:0006582 1 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
urogenital system development GO:0001655 65 0.019
regulation of protein stability GO:0031647 87 0.019
neuromuscular junction development GO:0007528 3 0.019
secretion by cell GO:0032940 226 0.019
gtp metabolic process GO:0046039 239 0.019
chromatin modification GO:0016568 298 0.019
nucleotide catabolic process GO:0009166 408 0.019
regulation of ras protein signal transduction GO:0046578 155 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.019
cellular amide metabolic process GO:0043603 69 0.019
actin filament based movement GO:0030048 17 0.019
heart development GO:0007507 95 0.019
t cell activation GO:0042110 99 0.018
cell projection organization GO:0030030 252 0.018
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.018
cellular response to cytokine stimulus GO:0071345 181 0.018
immune system development GO:0002520 195 0.018
peptide metabolic process GO:0006518 51 0.018
limb development GO:0060173 23 0.018
t cell selection GO:0045058 4 0.018
cell proliferation in forebrain GO:0021846 1 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018

BIK disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.050
myopathy DOID:423 104 0.046
muscular disease DOID:0080000 114 0.046
heart disease DOID:114 68 0.046
cardiomyopathy DOID:0050700 50 0.046
cardiovascular system disease DOID:1287 106 0.046
muscle tissue disease DOID:66 113 0.046
disease of metabolism DOID:0014667 295 0.035
inherited metabolic disorder DOID:655 242 0.031
central nervous system disease DOID:331 186 0.029
nervous system disease DOID:863 431 0.029
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
sensory system disease DOID:0050155 203 0.019
organ system cancer DOID:0050686 164 0.018