Homo sapiens

12 known processes

NOTCH4

notch 4

(Aliases: MGC74442,INT3,FLJ16302,NOTCH3)

NOTCH4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circulatory system development GO:0072359 262 0.466
Human Mouse Fly
blood vessel morphogenesis GO:0048514 162 0.456
Human Mouse
cardiovascular system development GO:0072358 262 0.443
Human Mouse Fly
regulation of locomotion GO:0040012 329 0.437
Human
vasculature development GO:0001944 181 0.335
Human Mouse
regulation of cellular component movement GO:0051270 334 0.307
Human
angiogenesis GO:0001525 147 0.292
Human Mouse
amine metabolic process GO:0009308 44 0.278
blood vessel development GO:0001568 172 0.256
Human Mouse
regulation of cell migration GO:0030334 289 0.252
Human
regulation of cellular amine metabolic process GO:0033238 11 0.248
negative regulation of cell migration GO:0030336 102 0.230
Human
cellular amino acid metabolic process GO:0006520 116 0.211
negative regulation of multicellular organismal process GO:0051241 317 0.201
Human Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.199
regulation of cell motility GO:2000145 299 0.198
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.197
cellular amine metabolic process GO:0044106 41 0.184
anatomical structure formation involved in morphogenesis GO:0048646 284 0.184
Human Mouse Fly
negative regulation of cellular component movement GO:0051271 106 0.184
Human
mapk cascade GO:0000165 288 0.182
positive regulation of cellular component organization GO:0051130 376 0.174
Human
negative regulation of locomotion GO:0040013 118 0.173
Human
taxis GO:0042330 157 0.171
Human Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.168
regulation of purine nucleotide metabolic process GO:1900542 264 0.165
ras protein signal transduction GO:0007265 73 0.160
Human
cellular ketone metabolic process GO:0042180 80 0.159
regulation of angiogenesis GO:0045765 92 0.157
Human
small gtpase mediated signal transduction GO:0007264 78 0.156
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.155
positive regulation of cell proliferation GO:0008284 301 0.153
Human Fly
positive regulation of protein phosphorylation GO:0001934 313 0.151
negative regulation of developmental process GO:0051093 247 0.150
Human Mouse Fly
regulation of nucleotide metabolic process GO:0006140 269 0.147
positive regulation of developmental process GO:0051094 314 0.138
Human
positive regulation of phosphorylation GO:0042327 394 0.137
epithelium migration GO:0090132 119 0.136
Human Fly
system process GO:0003008 349 0.136
Fly
actin filament based process GO:0030029 224 0.136
Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.136
regulation of mapk cascade GO:0043408 262 0.134
signal transduction by phosphorylation GO:0023014 297 0.133
positive regulation of mapk cascade GO:0043410 190 0.132
cation transport GO:0006812 331 0.132
cell development GO:0048468 328 0.129
Human Rat Fly
cellular response to endogenous stimulus GO:0071495 336 0.129
Human
positive regulation of hydrolase activity GO:0051345 331 0.126
organophosphate catabolic process GO:0046434 430 0.123
ribonucleoside catabolic process GO:0042454 406 0.119
purine nucleoside catabolic process GO:0006152 398 0.118
regulation of secretion GO:0051046 194 0.118
negative regulation of cell death GO:0060548 345 0.117
Human
response to growth factor GO:0070848 205 0.116
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.114
positive regulation of transport GO:0051050 336 0.113
regulation of kinase activity GO:0043549 314 0.112
regulation of cell differentiation GO:0045595 393 0.112
Human Mouse Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.112
regulation of establishment of protein localization GO:0070201 242 0.110
secretion GO:0046903 254 0.109
negative regulation of programmed cell death GO:0043069 321 0.108
Human
cell adhesion GO:0007155 325 0.107
Human Fly
epithelial cell migration GO:0010631 119 0.106
Human Fly
cyclic nucleotide metabolic process GO:0009187 82 0.105
nucleoside triphosphate metabolic process GO:0009141 422 0.105
regulation of vasculature development GO:1901342 97 0.104
Human
regulation of cellular component biogenesis GO:0044087 281 0.102
Fly
cellular response to growth factor stimulus GO:0071363 197 0.101
Human
purine containing compound catabolic process GO:0072523 411 0.101
sprouting angiogenesis GO:0002040 29 0.101
Human
positive regulation of catabolic process GO:0009896 310 0.101
post embryonic development GO:0009791 2 0.100
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.100
cellular component morphogenesis GO:0032989 314 0.097
Human Rat Fly
regulation of protein localization GO:0032880 296 0.097
regulation of transferase activity GO:0051338 355 0.096
response to organic cyclic compound GO:0014070 204 0.095
negative regulation of cell proliferation GO:0008285 228 0.095
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.094
Human Fly
response to abiotic stimulus GO:0009628 336 0.094
positive regulation of transferase activity GO:0051347 227 0.093
purine ribonucleotide catabolic process GO:0009154 404 0.092
regulation of protein kinase activity GO:0045859 289 0.091
urogenital system development GO:0001655 65 0.090
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.087
chemotaxis GO:0006935 157 0.086
Human Fly
organ morphogenesis GO:0009887 147 0.086
Human Fly
blood vessel endothelial cell migration GO:0043534 42 0.086
Human
nucleoside catabolic process GO:0009164 408 0.085
negative regulation of cell motility GO:2000146 104 0.085
Human
immune response GO:0006955 307 0.085
glycosyl compound catabolic process GO:1901658 413 0.084
ribonucleotide catabolic process GO:0009261 405 0.084
actin cytoskeleton organization GO:0030036 207 0.083
Fly
tissue migration GO:0090130 119 0.083
Human Fly
carbohydrate derivative biosynthetic process GO:1901137 207 0.082
purine nucleoside triphosphate metabolic process GO:0009144 412 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.081
cell morphogenesis GO:0000902 296 0.081
Human Rat Fly
positive regulation of protein kinase activity GO:0045860 190 0.080
regulation of gtp catabolic process GO:0033124 180 0.080
response to wounding GO:0009611 168 0.080
vesicle mediated transport GO:0016192 371 0.079
nucleotide catabolic process GO:0009166 408 0.079
positive regulation of locomotion GO:0040017 186 0.078
purine nucleotide catabolic process GO:0006195 405 0.077
regulation of ras protein signal transduction GO:0046578 155 0.077
Human
nervous system development GO:0007399 293 0.077
Fly
oogenesis GO:0048477 2 0.076
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.075
positive regulation of cellular catabolic process GO:0031331 284 0.075
purine ribonucleoside catabolic process GO:0046130 398 0.074
nucleoside triphosphate catabolic process GO:0009143 394 0.074
lipid metabolic process GO:0006629 381 0.074
ribonucleoside triphosphate catabolic process GO:0009203 391 0.073
purine ribonucleoside metabolic process GO:0046128 437 0.073
negative regulation of apoptotic process GO:0043066 316 0.073
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.073
Human
chemical homeostasis GO:0048878 306 0.073
endothelial cell migration GO:0043542 86 0.073
Human
purine ribonucleotide biosynthetic process GO:0009152 79 0.073
ribonucleotide biosynthetic process GO:0009260 81 0.073
response to oxygen containing compound GO:1901700 369 0.072
positive regulation of immune system process GO:0002684 283 0.072
nucleoside phosphate catabolic process GO:1901292 412 0.071
positive regulation of cell differentiation GO:0045597 211 0.071
Human
regulation of nucleotide catabolic process GO:0030811 205 0.071
ameboidal type cell migration GO:0001667 135 0.070
Human Fly
regulation of nucleotide biosynthetic process GO:0030808 50 0.070
epithelial cell proliferation GO:0050673 128 0.070
Fly
renal system development GO:0072001 63 0.070
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.069
female gamete generation GO:0007292 2 0.069
Fly
nucleoside phosphate biosynthetic process GO:1901293 109 0.069
positive regulation of kinase activity GO:0033674 204 0.068
mitotic cell cycle GO:0000278 326 0.068
Fly
guanosine containing compound metabolic process GO:1901068 244 0.067
membrane organization GO:0061024 292 0.067
biological adhesion GO:0022610 331 0.067
Human Fly
response to hormone GO:0009725 175 0.067
Human
epithelial cell differentiation GO:0030855 141 0.066
Mouse Rat Fly
rho protein signal transduction GO:0007266 26 0.066
hematopoietic or lymphoid organ development GO:0048534 186 0.065
Fly
positive regulation of cell migration GO:0030335 172 0.065
regulation of purine nucleotide catabolic process GO:0033121 205 0.064
camp biosynthetic process GO:0006171 47 0.064
single organism cellular localization GO:1902580 332 0.064
positive regulation of nucleoside metabolic process GO:0045979 186 0.063
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.063
regulation of cell cycle GO:0051726 393 0.062
Human Fly
defense response GO:0006952 315 0.062
positive regulation of cell motility GO:2000147 177 0.062
response to nitrogen compound GO:1901698 184 0.061
motor neuron axon guidance GO:0008045 2 0.061
Fly
cytokine production GO:0001816 247 0.060
positive regulation of cellular component movement GO:0051272 181 0.060
negative regulation of protein metabolic process GO:0051248 391 0.060
single organism cell adhesion GO:0098602 179 0.060
organophosphate biosynthetic process GO:0090407 163 0.059
response to other organism GO:0051707 261 0.059
Fly
regulation of cytokine production GO:0001817 232 0.059
regulation of protein transport GO:0051223 213 0.058
cellular response to oxygen containing compound GO:1901701 276 0.057
positive regulation of nucleotide catabolic process GO:0030813 185 0.057
regulation of camp biosynthetic process GO:0030817 45 0.056
secretion by cell GO:0032940 226 0.056
guanosine containing compound catabolic process GO:1901069 239 0.055
cell projection organization GO:0030030 252 0.055
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.055
regulation of epithelial cell migration GO:0010632 93 0.055
Human
regulation of endothelial cell migration GO:0010594 67 0.055
Human
regulation of cell adhesion GO:0030155 166 0.054
Human
regulation of nucleoside metabolic process GO:0009118 209 0.054
regulation of secretion by cell GO:1903530 177 0.054
leukocyte activation GO:0045321 164 0.054
gtp catabolic process GO:0006184 237 0.053
positive regulation of gtp catabolic process GO:0033126 166 0.053
positive regulation of cellular component biogenesis GO:0044089 158 0.053
positive regulation of cell death GO:0010942 263 0.052
regulation of cellular response to stress GO:0080135 244 0.052
regulation of epithelial cell proliferation GO:0050678 113 0.052
cell substrate adhesion GO:0031589 132 0.051
Human
immune system development GO:0002520 195 0.051
Fly
tube development GO:0035295 125 0.051
Human Mouse Fly
multicellular organismal aging GO:0010259 3 0.051
Fly
metal ion transport GO:0030001 272 0.051
cellular response to dna damage stimulus GO:0006974 379 0.050
hemopoiesis GO:0030097 180 0.050
Fly
determination of adult lifespan GO:0008340 2 0.049
Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.049
positive regulation of secretion by cell GO:1903532 108 0.049
cell morphogenesis involved in differentiation GO:0000904 144 0.048
Human Rat Fly
lipid biosynthetic process GO:0008610 177 0.048
positive regulation of cytokine production GO:0001819 167 0.048
transmembrane transport GO:0055085 399 0.048
gtp metabolic process GO:0046039 239 0.048
mitotic cell cycle process GO:1903047 286 0.047
Fly
epithelium development GO:0060429 227 0.047
Mouse Rat Fly
regulation of response to external stimulus GO:0032101 222 0.047
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.047
negative regulation of catalytic activity GO:0043086 335 0.046
cell junction organization GO:0034330 79 0.046
positive regulation of apoptotic process GO:0043065 246 0.046
actin filament organization GO:0007015 128 0.046
Fly
peptidyl tyrosine modification GO:0018212 170 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
positive regulation of protein transport GO:0051222 135 0.045
regulation of map kinase activity GO:0043405 108 0.045
peptidyl tyrosine phosphorylation GO:0018108 170 0.045
cyclic nucleotide biosynthetic process GO:0009190 61 0.044
cell activation GO:0001775 213 0.044
negative regulation of vasculature development GO:1901343 43 0.044
Human
regeneration GO:0031099 4 0.044
response to lipid GO:0033993 206 0.044
growth GO:0040007 202 0.043
Human Fly
regulation of response to wounding GO:1903034 101 0.043
positive regulation of map kinase activity GO:0043406 80 0.043
negative regulation of cellular component organization GO:0051129 235 0.043
response to organonitrogen compound GO:0010243 156 0.043
regulation of cytoskeleton organization GO:0051493 177 0.043
positive regulation of cell cycle GO:0045787 140 0.042
Fly
regulation of proteolysis GO:0030162 293 0.042
regulation of gtpase activity GO:0043087 180 0.042
apoptotic signaling pathway GO:0097190 268 0.042
positive regulation of epithelial cell proliferation GO:0050679 65 0.042
immune effector process GO:0002252 159 0.042
regulation of cell cycle process GO:0010564 266 0.041
Fly
cellular response to organic cyclic compound GO:0071407 127 0.041
regulation of actin filament based process GO:0032970 141 0.041
positive regulation of programmed cell death GO:0043068 249 0.041
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.041
stress activated protein kinase signaling cascade GO:0031098 94 0.040
erk1 and erk2 cascade GO:0070371 104 0.040
divalent inorganic cation transport GO:0072511 158 0.040
single organism membrane organization GO:0044802 268 0.040
activation of protein kinase activity GO:0032147 90 0.040
response to cytokine GO:0034097 232 0.040
regulation of ras gtpase activity GO:0032318 128 0.039
negative regulation of cell differentiation GO:0045596 171 0.039
Human Mouse Fly
calcium ion transport GO:0006816 147 0.039
response to external biotic stimulus GO:0043207 261 0.039
Fly
skeletal system development GO:0001501 79 0.039
cellular lipid metabolic process GO:0044255 303 0.039
endothelial cell proliferation GO:0001935 65 0.038
glial cell migration GO:0008347 4 0.038
Fly
positive regulation of gtpase activity GO:0043547 166 0.038
innate immune response GO:0045087 178 0.038
negative regulation of transport GO:0051051 176 0.038
cellular homeostasis GO:0019725 196 0.038
positive regulation of angiogenesis GO:0045766 51 0.038
regulation of peptidase activity GO:0052547 180 0.038
purine nucleotide biosynthetic process GO:0006164 84 0.037
blood circulation GO:0008015 113 0.037
positive regulation of secretion GO:0051047 116 0.037
intracellular protein transport GO:0006886 270 0.037
neurogenesis GO:0022008 169 0.037
Fly
regulation of immune response GO:0050776 201 0.037
protein processing GO:0016485 226 0.037
negative regulation of cell cycle GO:0045786 193 0.037
Human
cell projection assembly GO:0030031 126 0.036
Fly
cellular response to cytokine stimulus GO:0071345 181 0.036
purine containing compound biosynthetic process GO:0072522 88 0.036
metal ion homeostasis GO:0055065 169 0.036
wound healing GO:0042060 115 0.035
positive regulation of epithelial cell migration GO:0010634 55 0.035
blastoderm segmentation GO:0007350 2 0.035
ion transmembrane transport GO:0034220 338 0.035
negative regulation of phosphate metabolic process GO:0045936 267 0.035
cell growth GO:0016049 160 0.035
Human
regulation of mitotic cell cycle GO:0007346 189 0.035
Fly
divalent metal ion transport GO:0070838 152 0.035
dephosphorylation GO:0016311 209 0.035
carbohydrate metabolic process GO:0005975 207 0.034
protein maturation GO:0051604 233 0.034
response to biotic stimulus GO:0009607 276 0.034
Fly
segmentation GO:0035282 4 0.034
Fly
regulation of lipid metabolic process GO:0019216 96 0.034
locomotory behavior GO:0007626 1 0.033
heart development GO:0007507 95 0.033
Human Fly
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.033
calcium ion homeostasis GO:0055074 122 0.033
ribose phosphate biosynthetic process GO:0046390 82 0.032
regulation of system process GO:0044057 101 0.032
cyclic purine nucleotide metabolic process GO:0052652 60 0.032
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.032
salivary gland morphogenesis GO:0007435 4 0.032
positive regulation of organelle organization GO:0010638 195 0.032
protein catabolic process GO:0030163 325 0.032
cellular cation homeostasis GO:0030003 163 0.032
cellular response to organonitrogen compound GO:0071417 124 0.032
receptor metabolic process GO:0043112 81 0.032
neuromuscular junction development GO:0007528 3 0.032
negative regulation of epithelial cell migration GO:0010633 38 0.032
Human
generation of neurons GO:0048699 152 0.031
Fly
cellular chemical homeostasis GO:0055082 180 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.031
positive regulation of ras gtpase activity GO:0032320 117 0.031
circulatory system process GO:0003013 113 0.031
positive regulation of immune response GO:0050778 159 0.031
cytoplasmic transport GO:0016482 379 0.031
protein localization to organelle GO:0033365 280 0.031
hindbrain development GO:0030902 3 0.031
endocytosis GO:0006897 159 0.031
cellular macromolecular complex assembly GO:0034622 324 0.031
ion homeostasis GO:0050801 230 0.031
regulation of endopeptidase activity GO:0052548 170 0.030
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.030
nucleotide biosynthetic process GO:0009165 109 0.030
regulation of reactive oxygen species metabolic process GO:2000377 41 0.029
regulation of cell development GO:0060284 161 0.029
Human Fly
regulation of ion transport GO:0043269 189 0.029
regulation of erk1 and erk2 cascade GO:0070372 99 0.029
negative regulation of angiogenesis GO:0016525 39 0.029
Human
muscle contraction GO:0006936 73 0.029
response to decreased oxygen levels GO:0036293 96 0.029
connective tissue development GO:0061448 39 0.029
negative regulation of immune system process GO:0002683 136 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
anion transport GO:0006820 161 0.029
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.029
neuron development GO:0048666 113 0.029
Fly
protein targeting GO:0006605 187 0.028
protein oligomerization GO:0051259 173 0.028
lymphocyte activation GO:0046649 133 0.028
endomembrane system organization GO:0010256 196 0.028
neuron fate commitment GO:0048663 2 0.028
cellular divalent inorganic cation homeostasis GO:0072503 128 0.028
regulation of actin cytoskeleton organization GO:0032956 116 0.028
positive regulation of endothelial cell migration GO:0010595 39 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.028
protein ubiquitination GO:0016567 314 0.028
cell matrix adhesion GO:0007160 85 0.028
g protein coupled receptor signaling pathway GO:0007186 207 0.028
stress activated mapk cascade GO:0051403 93 0.028
cell cell signaling GO:0007267 155 0.028
Fly
cellular response to nitrogen compound GO:1901699 144 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
head development GO:0060322 108 0.027
reactive oxygen species metabolic process GO:0072593 75 0.027
nuclear transport GO:0051169 179 0.027
regulation of cell activation GO:0050865 125 0.027
regulation of endothelial cell proliferation GO:0001936 56 0.027
cell division GO:0051301 168 0.027
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.026
muscle system process GO:0003012 81 0.026
negative regulation of blood vessel morphogenesis GO:2000181 41 0.026
Human
neuron differentiation GO:0030182 138 0.026
Fly
regulation of intracellular transport GO:0032386 195 0.026
positive regulation of proteolysis GO:0045862 142 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
mitotic cell cycle phase transition GO:0044772 162 0.026
Fly
response to radiation GO:0009314 151 0.025
central nervous system development GO:0007417 123 0.025
cell type specific apoptotic process GO:0097285 125 0.025
regulation of protein secretion GO:0050708 86 0.025
regulation of anatomical structure size GO:0090066 101 0.025
oocyte development GO:0048599 1 0.025
negative regulation of protein modification process GO:0031400 200 0.025
kidney development GO:0001822 53 0.025
protein autophosphorylation GO:0046777 123 0.025
cell differentiation in spinal cord GO:0021515 1 0.025
ossification GO:0001503 121 0.025
phospholipid metabolic process GO:0006644 99 0.025
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.024
cell cycle phase transition GO:0044770 173 0.024
Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.024
response to hypoxia GO:0001666 96 0.024
inorganic ion transmembrane transport GO:0098660 231 0.024
regulation of nervous system development GO:0051960 88 0.024
Fly
regulation of cytoplasmic transport GO:1903649 149 0.024
regulation of dna metabolic process GO:0051052 153 0.024
single organism carbohydrate metabolic process GO:0044723 193 0.024
cellular ion homeostasis GO:0006873 168 0.024
dna replication GO:0006260 116 0.024
jnk cascade GO:0007254 80 0.024
regulation of cysteine type endopeptidase activity GO:2000116 127 0.024
negative regulation of protein processing GO:0010955 142 0.024
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.024
regulation of stress activated mapk cascade GO:0032872 84 0.024
regulation of rho protein signal transduction GO:0035023 79 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
positive regulation of cytoskeleton organization GO:0051495 83 0.024
protein localization to membrane GO:0072657 160 0.023
oocyte differentiation GO:0009994 2 0.023
pituitary gland development GO:0021983 2 0.023
gland development GO:0048732 48 0.023
regulation of hormone levels GO:0010817 125 0.023
anterior posterior axis specification GO:0009948 2 0.023
regulation of keratinocyte migration GO:0051547 4 0.023
positive regulation of odontogenesis GO:0042482 3 0.023
regulation of behavior GO:0050795 82 0.023
Human
regulation of neurogenesis GO:0050767 82 0.023
Fly
camp metabolic process GO:0046058 61 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
cell part morphogenesis GO:0032990 137 0.023
Fly
regulation of cell substrate adhesion GO:0010810 68 0.023
Human
neurological system process GO:0050877 163 0.023
Fly
cell projection morphogenesis GO:0048858 129 0.023
Fly
regulation of neuron differentiation GO:0045664 70 0.022
Fly
cell cell junction organization GO:0045216 69 0.022
cell fate determination GO:0001709 3 0.022
Fly
regulation of protein maturation GO:1903317 150 0.022
maintenance of location GO:0051235 112 0.022
cytokine secretion GO:0050663 64 0.022
cellular response to hormone stimulus GO:0032870 125 0.022
Human
muscle structure development GO:0061061 98 0.022
Human Fly
negative regulation of cell adhesion GO:0007162 64 0.022
Human
monocarboxylic acid metabolic process GO:0032787 185 0.022
negative regulation of protein maturation GO:1903318 142 0.022
cellular response to lipid GO:0071396 127 0.022
regulation of growth GO:0040008 165 0.022
Fly
angiogenesis involved in wound healing GO:0060055 4 0.022
muscle cell proliferation GO:0033002 35 0.022
neuron projection development GO:0031175 106 0.022
Fly
establishment of protein localization to membrane GO:0090150 121 0.022
protein import GO:0017038 130 0.021
cell junction assembly GO:0034329 67 0.021
regulation of camp metabolic process GO:0030814 52 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
single organismal cell cell adhesion GO:0016337 148 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
glycerolipid metabolic process GO:0046486 107 0.021
cellular metal ion homeostasis GO:0006875 146 0.021
long term memory GO:0007616 2 0.021
Fly
reactive nitrogen species metabolic process GO:2001057 3 0.021
positive regulation of camp biosynthetic process GO:0030819 35 0.021
leukocyte differentiation GO:0002521 98 0.021
myeloid cell differentiation GO:0030099 117 0.021
protein localization to nucleus GO:0034504 136 0.021
small molecule biosynthetic process GO:0044283 157 0.020
regulation of cell cycle phase transition GO:1901987 126 0.020
Fly
histone modification GO:0016570 251 0.020
lung alveolus development GO:0048286 4 0.020
morphogenesis of an epithelium GO:0002009 60 0.020
Mouse Fly
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
regulation of defense response GO:0031347 154 0.020
regulation of cell growth GO:0001558 135 0.020
protein secretion GO:0009306 98 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
somatic stem cell maintenance GO:0035019 4 0.020
response to oxygen levels GO:0070482 100 0.020
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.020
activation of mapk activity GO:0000187 45 0.020
heart morphogenesis GO:0003007 48 0.020
Human
response to axon injury GO:0048678 1 0.020
wnt signaling pathway GO:0016055 156 0.020
glycerophospholipid metabolic process GO:0006650 84 0.020
positive regulation of cell adhesion GO:0045785 84 0.020
chromatin organization GO:0006325 351 0.020
kidney epithelium development GO:0072073 25 0.020
peptidyl serine phosphorylation GO:0018105 101 0.020
positive regulation of neural precursor cell proliferation GO:2000179 2 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
organelle assembly GO:0070925 176 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
multicellular organismal homeostasis GO:0048871 67 0.019
positive regulation of cell development GO:0010720 92 0.019
Human
regulation of vesicle mediated transport GO:0060627 130 0.019
negative regulation of proteolysis GO:0045861 132 0.019
negative regulation of cell cycle process GO:0010948 121 0.019
regulation of protein catabolic process GO:0042176 155 0.019
regulation of mitotic cell cycle phase transition GO:1901990 118 0.019
Fly
tube morphogenesis GO:0035239 95 0.019
Human Mouse Fly
memory GO:0007613 3 0.019
Fly
regulation of metal ion transport GO:0010959 120 0.019
organ formation GO:0048645 3 0.019
Fly
hindlimb morphogenesis GO:0035137 2 0.019
plasma membrane organization GO:0007009 115 0.019
anatomical structure homeostasis GO:0060249 100 0.019
positive regulation of lipid metabolic process GO:0045834 50 0.019
interspecies interaction between organisms GO:0044419 156 0.019
nitrogen compound transport GO:0071705 191 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
tissue regeneration GO:0042246 3 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
neuroblast proliferation GO:0007405 4 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
cation transmembrane transport GO:0098655 238 0.019

NOTCH4 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.033
cardiovascular system disease DOID:1287 106 0.031
Human
disease of cellular proliferation DOID:14566 174 0.024
cancer DOID:162 167 0.024
organ system cancer DOID:0050686 164 0.024
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
disease of metabolism DOID:0014667 295 0.021
immune system disease DOID:2914 155 0.021
connective tissue disease DOID:65 109 0.019