Homo sapiens

38 known processes

NUP98

nucleoporin 98kDa

(Aliases: NUP196,ADIR2,NUP96)

NUP98 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna transport GO:0050658 39 0.993
nucleus organization GO:0006997 28 0.989
establishment of rna localization GO:0051236 39 0.986
cytoplasmic transport GO:0016482 379 0.960
Fly
nuclear transport GO:0051169 179 0.942
Fly
mrna transport GO:0051028 30 0.921
nucleic acid transport GO:0050657 39 0.918
nucleocytoplasmic transport GO:0006913 176 0.911
Fly
nuclear pore organization GO:0006999 10 0.867
rna localization GO:0006403 41 0.849
rna export from nucleus GO:0006405 33 0.846
nuclear pore complex assembly GO:0051292 7 0.810
cellular protein complex assembly GO:0043623 188 0.782
mrna export from nucleus GO:0006406 29 0.758
nucleobase containing compound transport GO:0015931 51 0.724
nuclear export GO:0051168 69 0.687
post embryonic development GO:0009791 2 0.657
Worm
pore complex assembly GO:0046931 9 0.620
nitrogen compound transport GO:0071705 191 0.590
regulation of cell cycle GO:0051726 393 0.527
single organism cellular localization GO:1902580 332 0.467
Fly
regulation of cell cycle process GO:0010564 266 0.387
cellular macromolecular complex assembly GO:0034622 324 0.376
microtubule cytoskeleton organization GO:0000226 176 0.363
embryo development GO:0009790 123 0.353
Worm
regulation of mitotic cell cycle GO:0007346 189 0.340
regulation of cytoplasmic transport GO:1903649 149 0.255
cell development GO:0048468 328 0.227
Worm Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.213
single organism nuclear import GO:1902593 104 0.200
Fly
regulation of intracellular transport GO:0032386 195 0.192
protein targeting to nucleus GO:0044744 104 0.190
Fly
establishment of protein localization to organelle GO:0072594 172 0.186
Fly
mitotic cell cycle GO:0000278 326 0.185
cell morphogenesis GO:0000902 296 0.181
chromatin organization GO:0006325 351 0.167
nervous system development GO:0007399 293 0.164
embryo development ending in birth or egg hatching GO:0009792 34 0.162
Worm
mitotic cell cycle phase transition GO:0044772 162 0.144
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.122
Fly
regulation of cellular component biogenesis GO:0044087 281 0.116
organelle fission GO:0048285 149 0.106
locomotory behavior GO:0007626 1 0.103
negative regulation of protein metabolic process GO:0051248 391 0.102
negative regulation of locomotion GO:0040013 118 0.101
nls bearing protein import into nucleus GO:0006607 2 0.099
cellular response to heat GO:0034605 14 0.095
nuclear import GO:0051170 106 0.094
Fly
negative regulation of proteolysis GO:0045861 132 0.093
cell cycle phase transition GO:0044770 173 0.091
regulation of mitotic cell cycle phase transition GO:1901990 118 0.087
female gamete generation GO:0007292 2 0.087
Worm
regulation of nucleobase containing compound transport GO:0032239 7 0.086
intracellular protein transport GO:0006886 270 0.081
Fly
multicellular organismal aging GO:0010259 3 0.081
regulation of mrna export from nucleus GO:0010793 3 0.078
negative regulation of cellular protein metabolic process GO:0032269 353 0.070
determination of adult lifespan GO:0008340 2 0.069
regulation of protein localization GO:0032880 296 0.068
neural tube formation GO:0001841 3 0.068
chromatin modification GO:0016568 298 0.066
blastocyst development GO:0001824 3 0.066
response to abiotic stimulus GO:0009628 336 0.065
rna 3 end processing GO:0031123 35 0.065
microtubule based process GO:0007017 210 0.064
neurogenesis GO:0022008 169 0.062
protein targeting GO:0006605 187 0.057
Fly
oogenesis GO:0048477 2 0.057
Worm
negative regulation of apoptotic process GO:0043066 316 0.057
g1 s transition of mitotic cell cycle GO:0000082 78 0.057
protein localization to nucleus GO:0034504 136 0.056
Fly
protein localization to organelle GO:0033365 280 0.054
Fly
growth GO:0040007 202 0.052
negative regulation of transport GO:0051051 176 0.052
hematopoietic or lymphoid organ development GO:0048534 186 0.051
small gtpase mediated signal transduction GO:0007264 78 0.051
tube morphogenesis GO:0035239 95 0.051
negative regulation of programmed cell death GO:0043069 321 0.049
negative regulation of cell proliferation GO:0008285 228 0.049
protein import into nucleus GO:0006606 104 0.047
Fly
signal transduction by phosphorylation GO:0023014 297 0.047
mitotic nuclear division GO:0007067 119 0.046
chordate embryonic development GO:0043009 34 0.046
regulation of protein maturation GO:1903317 150 0.045
centrosome organization GO:0051297 58 0.045
mitotic cell cycle process GO:1903047 286 0.043
regulation of chromosome organization GO:0033044 103 0.043
regulation of cell cycle phase transition GO:1901987 126 0.043
regulation of protein complex assembly GO:0043254 147 0.041
chromatin assembly GO:0031497 61 0.040
modification dependent protein catabolic process GO:0019941 209 0.039
protein processing GO:0016485 226 0.039
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
negative regulation of organelle organization GO:0010639 126 0.038
cytokinesis GO:0000910 96 0.037
cell division GO:0051301 168 0.037
protein export from nucleus GO:0006611 29 0.036
microtubule organizing center organization GO:0031023 62 0.036
cellular amine metabolic process GO:0044106 41 0.035
negative regulation of cell cycle GO:0045786 193 0.035
protein catabolic process GO:0030163 325 0.035
methylation GO:0032259 106 0.035
reproductive process GO:0022414 106 0.034
Worm
cellular component morphogenesis GO:0032989 314 0.034
regulation of protein processing GO:0070613 150 0.034
response to temperature stimulus GO:0009266 22 0.034
single organism reproductive process GO:0044702 98 0.034
Worm
regulation of protein import into nucleus GO:0042306 78 0.033
negative regulation of multicellular organismal process GO:0051241 317 0.033
mapk cascade GO:0000165 288 0.033
regulation of protein transport GO:0051223 213 0.033
endocytosis GO:0006897 159 0.033
Fly
negative regulation of cellular component organization GO:0051129 235 0.033
protein acylation GO:0043543 138 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
regulation of nuclear division GO:0051783 65 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
smad protein import into nucleus GO:0007184 13 0.031
Fly
regulation of cell cycle g1 s phase transition GO:1902806 42 0.030
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
cell cycle g1 s phase transition GO:0044843 80 0.029
regulation of meiotic cell cycle GO:0051445 4 0.029
mrna metabolic process GO:0016071 175 0.029
cardiovascular system development GO:0072358 262 0.028
negative regulation of developmental process GO:0051093 247 0.028
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.028
histone acetylation GO:0016573 93 0.028
protein import GO:0017038 130 0.027
Fly
system process GO:0003008 349 0.027
cellular component disassembly GO:0022411 92 0.027
neuromuscular junction development GO:0007528 3 0.027
rna processing GO:0006396 255 0.027
cellular ketone metabolic process GO:0042180 80 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.026
negative regulation of protein maturation GO:1903318 142 0.026
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.026
positive regulation of immune system process GO:0002684 283 0.026
tube development GO:0035295 125 0.026
sister chromatid segregation GO:0000819 54 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
regulation of growth GO:0040008 165 0.025
nuclear division GO:0000280 128 0.025
macromolecular complex disassembly GO:0032984 60 0.024
meiosis i GO:0007127 4 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
chromosome segregation GO:0007059 114 0.024
negative regulation of cell death GO:0060548 345 0.024
regulation of intracellular protein transport GO:0033157 123 0.023
reproduction GO:0000003 63 0.023
Worm
regulation of cytoskeleton organization GO:0051493 177 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
nucleosome organization GO:0034728 66 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
negative regulation of catabolic process GO:0009895 104 0.022
purine nucleoside monophosphate metabolic process GO:0009126 186 0.022
negative regulation of protein processing GO:0010955 142 0.022
macromolecule methylation GO:0043414 97 0.022
amine metabolic process GO:0009308 44 0.022
spermatid differentiation GO:0048515 4 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
regulation of chromatin organization GO:1902275 56 0.021
covalent chromatin modification GO:0016569 254 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
vesicle mediated transport GO:0016192 371 0.021
Fly
regulation of protein targeting GO:1903533 91 0.021
negative regulation of cytoplasmic transport GO:1903650 46 0.021
protein methylation GO:0006479 74 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.020
negative regulation of mitotic cell cycle GO:0045930 102 0.020
circadian behavior GO:0048512 2 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
skin development GO:0043588 76 0.020
mitotic spindle elongation GO:0000022 4 0.020
regeneration GO:0031099 4 0.020
positive regulation of cell death GO:0010942 263 0.020
regulation of protein localization to nucleus GO:1900180 85 0.020
actin cytoskeleton organization GO:0030036 207 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
cellular component assembly involved in morphogenesis GO:0010927 73 0.019
vasculature development GO:0001944 181 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
ras protein signal transduction GO:0007265 73 0.019
receptor mediated endocytosis GO:0006898 84 0.019
negative regulation of chromosome organization GO:2001251 48 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.019
histone modification GO:0016570 251 0.019
oocyte development GO:0048599 1 0.019
Worm
protein maturation GO:0051604 233 0.019
cell adhesion GO:0007155 325 0.018
regulation of transcription by chromatin organization GO:0034401 1 0.018
dna conformation change GO:0071103 113 0.018
membrane organization GO:0061024 292 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
regulation of cell development GO:0060284 161 0.018
regulation of locomotion GO:0040012 329 0.017
nucleoside catabolic process GO:0009164 408 0.017
carbohydrate metabolic process GO:0005975 207 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
sexual reproduction GO:0019953 37 0.017
Worm
chromatin remodeling GO:0006338 55 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
positive regulation of protein transport GO:0051222 135 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
regulation of mrna metabolic process GO:1903311 53 0.016
defense response to other organism GO:0098542 129 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
positive regulation of protein import into nucleus GO:0042307 46 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
regulation of translation GO:0006417 89 0.016
glycoprotein biosynthetic process GO:0009101 91 0.016
protein modification by small protein removal GO:0070646 92 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
regulation of rna stability GO:0043487 23 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
regulation of proteolysis GO:0030162 293 0.015
cellular protein complex disassembly GO:0043624 36 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
regulation of chromatin modification GO:1903308 51 0.015
cell projection organization GO:0030030 252 0.015
negative regulation of protein modification process GO:0031400 200 0.015
positive regulation of nfat protein import into nucleus GO:0051533 3 0.015
organelle localization GO:0051640 84 0.015
regulation of histone modification GO:0031056 47 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
spermatid development GO:0007286 4 0.015
neuron projection development GO:0031175 106 0.015
peripheral nervous system development GO:0007422 2 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.014
segmentation GO:0035282 4 0.014
Worm
adult locomotory behavior GO:0008344 1 0.014
compound eye development GO:0048749 1 0.014
negative regulation of growth GO:0045926 97 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
cellular protein complex localization GO:0034629 8 0.014
regulation of mitosis GO:0007088 63 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
maturation of ssu rrna GO:0030490 3 0.014
neurological system process GO:0050877 163 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
single organism membrane organization GO:0044802 268 0.014
pattern specification process GO:0007389 43 0.014
Worm
organ morphogenesis GO:0009887 147 0.013
transmembrane transport GO:0055085 399 0.013
regulation of mrna stability GO:0043488 23 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
regulation of nervous system development GO:0051960 88 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
lipid metabolic process GO:0006629 381 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.012
protein localization to membrane GO:0072657 160 0.012
reproductive structure development GO:0048608 55 0.012
Worm
purine ribonucleotide catabolic process GO:0009154 404 0.012
regulation of chromosome segregation GO:0051983 44 0.012
dna packaging GO:0006323 77 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
memory GO:0007613 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
Fly
anterior posterior axis specification GO:0009948 2 0.012
Worm
apoptotic signaling pathway GO:0097190 268 0.012
internal protein amino acid acetylation GO:0006475 101 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.012
regulation of protein kinase activity GO:0045859 289 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
regulation of kinase activity GO:0043549 314 0.011
cellular protein catabolic process GO:0044257 261 0.011
generation of neurons GO:0048699 152 0.011
regulation of meiosis GO:0040020 3 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
mrna 3 end processing GO:0031124 24 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of defense response GO:0031347 154 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
protein acetylation GO:0006473 116 0.010
single organism carbohydrate metabolic process GO:0044723 193 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
skeletal system development GO:0001501 79 0.010
embryonic morphogenesis GO:0048598 85 0.010
heterochromatin assembly GO:0031507 6 0.010
immune response GO:0006955 307 0.010

NUP98 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.132
cancer DOID:162 167 0.094
organ system cancer DOID:0050686 164 0.094
central nervous system disease DOID:331 186 0.016
neurodegenerative disease DOID:1289 102 0.016
nervous system disease DOID:863 431 0.016
disease of mental health DOID:150 70 0.013