Homo sapiens

0 known processes

KPNA6

karyopherin alpha 6 (importin alpha 7)

(Aliases: KPNA7,FLJ11249,IPOA7,MGC17918)

KPNA6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular protein transport GO:0006886 270 0.218
Mouse
post embryonic development GO:0009791 2 0.137
nucleocytoplasmic transport GO:0006913 176 0.135
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.128
protein localization to organelle GO:0033365 280 0.103
Mouse
negative regulation of programmed cell death GO:0043069 321 0.096
single organism cellular localization GO:1902580 332 0.096
Mouse
regulation of nucleocytoplasmic transport GO:0046822 98 0.094
nuclear transport GO:0051169 179 0.094
Mouse
positive regulation of intracellular protein transport GO:0090316 76 0.089
blastoderm segmentation GO:0007350 2 0.087
regulation of protein localization GO:0032880 296 0.086
cytoplasmic transport GO:0016482 379 0.086
Mouse
female gamete generation GO:0007292 2 0.084
cellular macromolecular complex assembly GO:0034622 324 0.080
establishment of protein localization to organelle GO:0072594 172 0.079
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.079
oogenesis GO:0048477 2 0.079
chromatin modification GO:0016568 298 0.079
positive regulation of transport GO:0051050 336 0.074
protein catabolic process GO:0030163 325 0.072
regulation of establishment of protein localization GO:0070201 242 0.071
anterior posterior axis specification GO:0009948 2 0.065
regulation of intracellular protein transport GO:0033157 123 0.065
negative regulation of protein metabolic process GO:0051248 391 0.064
chromatin organization GO:0006325 351 0.059
segmentation GO:0035282 4 0.059
positive regulation of protein transport GO:0051222 135 0.056
positive regulation of intracellular transport GO:0032388 104 0.056
covalent chromatin modification GO:0016569 254 0.055
positive regulation of cytoplasmic transport GO:1903651 82 0.054
regulation of cytoplasmic transport GO:1903649 149 0.052
small gtpase mediated signal transduction GO:0007264 78 0.050
protein maturation GO:0051604 233 0.049
protein dna complex subunit organization GO:0071824 80 0.049
ribonucleoprotein complex biogenesis GO:0022613 116 0.048
regulation of cell cycle GO:0051726 393 0.048
protein localization to nucleus GO:0034504 136 0.048
Mouse
locomotory behavior GO:0007626 1 0.047
posttranscriptional regulation of gene expression GO:0010608 213 0.047
regulation of protein transport GO:0051223 213 0.047
multicellular organismal aging GO:0010259 3 0.046
cell development GO:0048468 328 0.046
cellular lipid metabolic process GO:0044255 303 0.045
mitotic cell cycle GO:0000278 326 0.045
protein targeting GO:0006605 187 0.043
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.042
nucleoside triphosphate catabolic process GO:0009143 394 0.040
determination of adult lifespan GO:0008340 2 0.040
ras protein signal transduction GO:0007265 73 0.040
amine metabolic process GO:0009308 44 0.038
cellular protein catabolic process GO:0044257 261 0.038
cellular macromolecule catabolic process GO:0044265 380 0.038
single organism nuclear import GO:1902593 104 0.038
Mouse
cellular component morphogenesis GO:0032989 314 0.038
oocyte differentiation GO:0009994 2 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
regulation of intracellular transport GO:0032386 195 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.034
vesicle mediated transport GO:0016192 371 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
modification dependent protein catabolic process GO:0019941 209 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
tripartite regional subdivision GO:0007351 2 0.031
organophosphate catabolic process GO:0046434 430 0.031
atp dependent chromatin remodeling GO:0043044 25 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
histone modification GO:0016570 251 0.031
actin filament based process GO:0030029 224 0.030
regulation of nucleotide metabolic process GO:0006140 269 0.030
protein dna complex assembly GO:0065004 64 0.030
regulation of protein localization to nucleus GO:1900180 85 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
nuclear migration GO:0007097 1 0.030
protein processing GO:0016485 226 0.029
lipid metabolic process GO:0006629 381 0.029
regulation of small gtpase mediated signal transduction GO:0051056 156 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
regulation of peptidase activity GO:0052547 180 0.029
purine containing compound catabolic process GO:0072523 411 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
negative regulation of protein modification process GO:0031400 200 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
dephosphorylation GO:0016311 209 0.029
negative regulation of cell death GO:0060548 345 0.028
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.028
response to abiotic stimulus GO:0009628 336 0.028
small molecule biosynthetic process GO:0044283 157 0.028
nucleotide catabolic process GO:0009166 408 0.028
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
positive regulation of protein localization to nucleus GO:1900182 48 0.028
cellular ketone metabolic process GO:0042180 80 0.028
regulation of cell growth GO:0001558 135 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
rna interference GO:0016246 4 0.027
nucleoside catabolic process GO:0009164 408 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
organic hydroxy compound metabolic process GO:1901615 147 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
regulation of cell cycle process GO:0010564 266 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
intracellular mrna localization GO:0008298 1 0.026
alcohol metabolic process GO:0006066 114 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
positive regulation of gtpase activity GO:0043547 166 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
membrane organization GO:0061024 292 0.025
rna processing GO:0006396 255 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
mitotic cell cycle process GO:1903047 286 0.024
cell competition in a multicellular organism GO:0035212 1 0.024
protein ubiquitination GO:0016567 314 0.024
microtubule based process GO:0007017 210 0.024
lipid biosynthetic process GO:0008610 177 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
response to nitrogen compound GO:1901698 184 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.024
glycerolipid metabolic process GO:0046486 107 0.024
immune response GO:0006955 307 0.023
dna conformation change GO:0071103 113 0.023
response to fungus GO:0009620 4 0.023
carbohydrate metabolic process GO:0005975 207 0.023
extrinsic apoptotic signaling pathway GO:0097191 119 0.023
protein acylation GO:0043543 138 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
rho protein signal transduction GO:0007266 26 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
protein import into nucleus GO:0006606 104 0.023
Mouse
nervous system development GO:0007399 293 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
anterior posterior axis specification embryo GO:0008595 2 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
memory GO:0007613 3 0.023
organelle assembly GO:0070925 176 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
neural tube formation GO:0001841 3 0.023
regulation of endopeptidase activity GO:0052548 170 0.022
ribonucleoprotein complex subunit organization GO:0071826 81 0.022
regulation of protein kinase activity GO:0045859 289 0.022
oocyte development GO:0048599 1 0.022
regulation of proteolysis GO:0030162 293 0.022
peptidyl lysine acetylation GO:0018394 101 0.022
protein acetylation GO:0006473 116 0.022
immune system development GO:0002520 195 0.022
negative regulation of developmental process GO:0051093 247 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
transmembrane transport GO:0055085 399 0.021
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
response to hormone GO:0009725 175 0.021
forebrain neuron differentiation GO:0021879 3 0.021
histone exchange GO:0043486 3 0.021
positive regulation of gtp catabolic process GO:0033126 166 0.021
cell growth GO:0016049 160 0.021
cellular protein complex assembly GO:0043623 188 0.021
response to oxygen containing compound GO:1901700 369 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.020
protein targeting to nucleus GO:0044744 104 0.020
Mouse
regulation of gtpase activity GO:0043087 180 0.020
positive regulation of catabolic process GO:0009896 310 0.020
single organism reproductive process GO:0044702 98 0.020
Mouse Fly
regulation of growth GO:0040008 165 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
gtp metabolic process GO:0046039 239 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
reproductive process GO:0022414 106 0.020
Mouse Fly
system process GO:0003008 349 0.019
cellular amine metabolic process GO:0044106 41 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
nuclear export GO:0051168 69 0.019
forebrain generation of neurons GO:0021872 3 0.019
single organism membrane organization GO:0044802 268 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
nucleosome organization GO:0034728 66 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
spermatid differentiation GO:0048515 4 0.019
cell projection organization GO:0030030 252 0.018
apoptotic signaling pathway GO:0097190 268 0.018
innate immune response GO:0045087 178 0.018
spermatid development GO:0007286 4 0.018
regeneration GO:0031099 4 0.018
protein import GO:0017038 130 0.018
Mouse
embryonic epithelial tube formation GO:0001838 4 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
wnt signaling pathway GO:0016055 156 0.018
organic hydroxy compound biosynthetic process GO:1901617 71 0.018
cell morphogenesis GO:0000902 296 0.017
endocytosis GO:0006897 159 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
rna splicing GO:0008380 131 0.017
cell projection morphogenesis GO:0048858 129 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
response to organonitrogen compound GO:0010243 156 0.017
lipid transport GO:0006869 90 0.017
mrna metabolic process GO:0016071 175 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
negative regulation of protein kinase activity GO:0006469 98 0.017
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.017
rhythmic behavior GO:0007622 2 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
meiosis i GO:0007127 4 0.016
organic hydroxy compound transport GO:0015850 63 0.016
oxidation reduction process GO:0055114 396 0.016
negative regulation of cell cycle GO:0045786 193 0.016
ribonucleoprotein complex assembly GO:0022618 78 0.016
phospholipid metabolic process GO:0006644 99 0.016
regulation of protein targeting GO:1903533 91 0.016
response to cytokine GO:0034097 232 0.016
growth GO:0040007 202 0.016
histone h3 acetylation GO:0043966 45 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of cell differentiation GO:0045595 393 0.016
protein oligomerization GO:0051259 173 0.016
inner ear morphogenesis GO:0042472 4 0.016
neuromuscular junction development GO:0007528 3 0.015
cerebral cortex cell migration GO:0021795 3 0.015
response to organic cyclic compound GO:0014070 204 0.015
positive regulation of peptidase activity GO:0010952 88 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
secretion GO:0046903 254 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
neurogenesis GO:0022008 169 0.015
epithelium development GO:0060429 227 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
atp metabolic process GO:0046034 176 0.015
secretion by cell GO:0032940 226 0.015
peptidyl lysine modification GO:0018205 144 0.015
generation of neurons GO:0048699 152 0.015
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.014
cellular response to nutrient levels GO:0031669 69 0.014
translation GO:0006412 132 0.014
regulation of multi organism process GO:0043900 157 0.014
multi organism cellular process GO:0044764 156 0.014
organelle fission GO:0048285 149 0.014
ncrna metabolic process GO:0034660 108 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
regulation of transcription factor import into nucleus GO:0042990 39 0.014
protein localization to membrane GO:0072657 160 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
adult locomotory behavior GO:0008344 1 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
mrna processing GO:0006397 133 0.014
regulation of transferase activity GO:0051338 355 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
histone acetylation GO:0016573 93 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
neurological system process GO:0050877 163 0.013
negative regulation of proteolysis GO:0045861 132 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
response to light stimulus GO:0009416 87 0.013
actin cytoskeleton organization GO:0030036 207 0.013
chromatin assembly GO:0031497 61 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
regulation of protein stability GO:0031647 87 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
regulation of kinase activity GO:0043549 314 0.013
regulation of response to external stimulus GO:0032101 222 0.013
metal ion transport GO:0030001 272 0.013
alcohol biosynthetic process GO:0046165 52 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
cation transport GO:0006812 331 0.013
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
cation transmembrane transport GO:0098655 238 0.013
positive regulation of nfat protein import into nucleus GO:0051533 3 0.013
somitogenesis GO:0001756 2 0.013
dna packaging GO:0006323 77 0.013
interspecies interaction between organisms GO:0044419 156 0.012
regulation of protein processing GO:0070613 150 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
lipid localization GO:0010876 106 0.012
defense response to fungus GO:0050832 4 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
positive regulation of proteolysis GO:0045862 142 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
mitochondrion organization GO:0007005 156 0.012
circadian behavior GO:0048512 2 0.012
nerve development GO:0021675 4 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
mating GO:0007618 1 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
forebrain neuron development GO:0021884 2 0.012
regulation of translation GO:0006417 89 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
semaphorin plexin signaling pathway GO:0071526 4 0.012
positive regulation of cell death GO:0010942 263 0.012
regulation of protein import into nucleus GO:0042306 78 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
embryo development GO:0009790 123 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
positive regulation of protein import into nucleus GO:0042307 46 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of phosphatase activity GO:0010921 81 0.012
anion transport GO:0006820 161 0.012
regulation of cell motility GO:2000145 299 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.011
nucleus localization GO:0051647 1 0.011
regulation of secretion by cell GO:1903530 177 0.011
establishment of nucleus localization GO:0040023 1 0.011
negative regulation of protein maturation GO:1903318 142 0.011
mitotic nuclear division GO:0007067 119 0.011
response to biotic stimulus GO:0009607 276 0.011
cell part morphogenesis GO:0032990 137 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
negative regulation of organelle organization GO:0010639 126 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
regulation of secretion GO:0051046 194 0.011
nitrogen compound transport GO:0071705 191 0.011
protein polyubiquitination GO:0000209 110 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
multi organism reproductive process GO:0044703 54 0.011
Mouse Fly
regulation of protein catabolic process GO:0042176 155 0.011
organelle localization GO:0051640 84 0.011
zymogen activation GO:0031638 70 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
tissue regeneration GO:0042246 3 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
neuron development GO:0048666 113 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
Mouse Fly
myoblast fusion GO:0007520 1 0.011
monovalent inorganic cation transport GO:0015672 128 0.010
epithelial cell differentiation GO:0030855 141 0.010
viral process GO:0016032 146 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
response to inorganic substance GO:0010035 127 0.010
thymus development GO:0048538 3 0.010
regulation of protein maturation GO:1903317 150 0.010
negative regulation of kinase activity GO:0033673 106 0.010
response to oxidative stress GO:0006979 121 0.010
behavioral response to ethanol GO:0048149 2 0.010
response to metal ion GO:0010038 84 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
cell cycle g2 m phase transition GO:0044839 43 0.010
rna splicing via transesterification reactions GO:0000375 90 0.010
negative regulation of locomotion GO:0040013 118 0.010
negative regulation of protein processing GO:0010955 142 0.010
negative regulation of cell growth GO:0030308 83 0.010
endosomal transport GO:0016197 129 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
cell cycle phase transition GO:0044770 173 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
regulation of viral process GO:0050792 103 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
regulation of rho protein signal transduction GO:0035023 79 0.010

KPNA6 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.036
myopathy DOID:423 104 0.031
muscular disease DOID:0080000 114 0.031
muscle tissue disease DOID:66 113 0.031
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
muscular dystrophy DOID:9884 51 0.019
neurodegenerative disease DOID:1289 102 0.014
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
disease of cellular proliferation DOID:14566 174 0.013
immune system disease DOID:2914 155 0.012
eye disease DOID:5614 149 0.012
retinal disease DOID:5679 118 0.012
limb girdle muscular dystrophy DOID:11724 25 0.010
synucleinopathy DOID:0050890 22 0.010