Homo sapiens

188 known processes

EIF2B5

eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

(Aliases: LVWM,CLE,EIF2Bepsilon,CACH,EIF-2B)

EIF2B5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oligodendrocyte development GO:0014003 6 0.794
ribonucleoside triphosphate metabolic process GO:0009199 412 0.526
glycosyl compound catabolic process GO:1901658 413 0.465
purine ribonucleotide catabolic process GO:0009154 404 0.464
nucleoside triphosphate metabolic process GO:0009141 422 0.447
purine nucleotide catabolic process GO:0006195 405 0.413
nucleoside triphosphate catabolic process GO:0009143 394 0.386
ribonucleoside catabolic process GO:0042454 406 0.356
transmission of nerve impulse GO:0019226 11 0.339
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.316
purine nucleoside triphosphate metabolic process GO:0009144 412 0.315
gtp catabolic process GO:0006184 237 0.313
post embryonic development GO:0009791 2 0.304
Worm
gtp metabolic process GO:0046039 239 0.298
positive regulation of nucleotide metabolic process GO:0045981 230 0.281
purine ribonucleoside metabolic process GO:0046128 437 0.273
nucleoside phosphate catabolic process GO:1901292 412 0.258
guanosine containing compound metabolic process GO:1901068 244 0.253
nucleoside catabolic process GO:0009164 408 0.244
nucleotide catabolic process GO:0009166 408 0.242
purine ribonucleoside catabolic process GO:0046130 398 0.240
positive regulation of gtp catabolic process GO:0033126 166 0.238
regulation of gtpase activity GO:0043087 180 0.222
positive regulation of nucleotide catabolic process GO:0030813 185 0.215
regulation of gtp catabolic process GO:0033124 180 0.204
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.193
neuronal action potential GO:0019228 9 0.192
regulation of purine nucleotide catabolic process GO:0033121 205 0.191
purine containing compound catabolic process GO:0072523 411 0.185
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.175
regulation of nucleoside metabolic process GO:0009118 209 0.174
regulation of purine nucleotide metabolic process GO:1900542 264 0.173
positive regulation of nucleoside metabolic process GO:0045979 186 0.166
ribonucleotide catabolic process GO:0009261 405 0.162
positive regulation of gtpase activity GO:0043547 166 0.162
vesicle mediated transport GO:0016192 371 0.155
purine nucleoside catabolic process GO:0006152 398 0.145
guanosine containing compound catabolic process GO:1901069 239 0.119
ribonucleoside triphosphate catabolic process GO:0009203 391 0.113
positive regulation of hydrolase activity GO:0051345 331 0.111
multicellular organismal signaling GO:0035637 34 0.105
positive regulation of cellular catabolic process GO:0031331 284 0.102
regulation of nucleotide metabolic process GO:0006140 269 0.090
nervous system development GO:0007399 293 0.088
cell development GO:0048468 328 0.086
translation GO:0006412 132 0.082
regulation of membrane potential GO:0042391 95 0.077
central nervous system development GO:0007417 123 0.077
regulation of cell cycle process GO:0010564 266 0.069
positive regulation of catabolic process GO:0009896 310 0.067
multicellular organismal aging GO:0010259 3 0.066
glial cell development GO:0021782 7 0.066
system process GO:0003008 349 0.066
regulation of translational initiation GO:0006446 24 0.063
Yeast Rat
organophosphate catabolic process GO:0046434 430 0.061
determination of adult lifespan GO:0008340 2 0.059
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
posttranscriptional regulation of gene expression GO:0010608 213 0.052
Yeast Rat
neurogenesis GO:0022008 169 0.051
nucleoside monophosphate metabolic process GO:0009123 191 0.050
cellular macromolecular complex assembly GO:0034622 324 0.048
cellular amino acid metabolic process GO:0006520 116 0.048
neuromuscular junction development GO:0007528 3 0.048
reproductive structure development GO:0048608 55 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.045
neurological system process GO:0050877 163 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.043
regulation of translation GO:0006417 89 0.041
Yeast Rat
sex differentiation GO:0007548 45 0.040
carbohydrate derivative biosynthetic process GO:1901137 207 0.040
gliogenesis GO:0042063 21 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.037
oligodendrocyte differentiation GO:0048709 7 0.037
endocytosis GO:0006897 159 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
regulation of cell cycle GO:0051726 393 0.035
positive regulation of developmental process GO:0051094 314 0.035
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.035
embryo development GO:0009790 123 0.034
Worm
receptor mediated endocytosis GO:0006898 84 0.033
ribonucleoside monophosphate metabolic process GO:0009161 187 0.033
mitotic cell cycle process GO:1903047 286 0.032
female gamete generation GO:0007292 2 0.031
mitochondrion organization GO:0007005 156 0.031
amine metabolic process GO:0009308 44 0.030
rna interference GO:0016246 4 0.030
regulation of growth GO:0040008 165 0.030
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.029
cellular ketone metabolic process GO:0042180 80 0.029
glial cell differentiation GO:0010001 11 0.028
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
ribonucleoprotein complex assembly GO:0022618 78 0.028
mitotic cell cycle GO:0000278 326 0.027
cellular amine metabolic process GO:0044106 41 0.027
female gonad development GO:0008585 10 0.027
mitotic cell cycle phase transition GO:0044772 162 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cytoplasmic transport GO:0016482 379 0.024
single organism reproductive process GO:0044702 98 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.023
oogenesis GO:0048477 2 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
lipid metabolic process GO:0006629 381 0.022
growth GO:0040007 202 0.022
Worm
regulation of meiotic cell cycle GO:0051445 4 0.022
reproductive process GO:0022414 106 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
viral process GO:0016032 146 0.021
negative regulation of catalytic activity GO:0043086 335 0.020
cell morphogenesis GO:0000902 296 0.020
protein localization to organelle GO:0033365 280 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
regulation of cellular response to stress GO:0080135 244 0.020
translational initiation GO:0006413 48 0.020
interspecies interaction between organisms GO:0044419 156 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
single organism membrane organization GO:0044802 268 0.020
negative regulation of developmental process GO:0051093 247 0.019
response to oxygen containing compound GO:1901700 369 0.019
Rat
atp metabolic process GO:0046034 176 0.019
rhythmic process GO:0048511 31 0.019
cell cycle phase transition GO:0044770 173 0.019
developmental process involved in reproduction GO:0003006 66 0.019
response to abiotic stimulus GO:0009628 336 0.018
regulation of meiosis GO:0040020 3 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
Rat
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
regulation of mitotic cell cycle GO:0007346 189 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
Rat
dephosphorylation GO:0016311 209 0.017
atp catabolic process GO:0006200 157 0.017
regulation of protein transport GO:0051223 213 0.017
viral life cycle GO:0019058 132 0.017
multi organism cellular process GO:0044764 156 0.017
organelle assembly GO:0070925 176 0.017
rna splicing GO:0008380 131 0.017
locomotory behavior GO:0007626 1 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
ras protein signal transduction GO:0007265 73 0.017
ribose phosphate biosynthetic process GO:0046390 82 0.017
protein maturation GO:0051604 233 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
single organism cellular localization GO:1902580 332 0.017
cell division GO:0051301 168 0.016
developmental growth GO:0048589 48 0.016
Worm
cellular protein complex assembly GO:0043623 188 0.016
positive regulation of transport GO:0051050 336 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
actin filament based process GO:0030029 224 0.016
reproduction GO:0000003 63 0.016
memory GO:0007613 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
metal ion transport GO:0030001 272 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
biological adhesion GO:0022610 331 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
cellular component morphogenesis GO:0032989 314 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
segmentation GO:0035282 4 0.015
methylation GO:0032259 106 0.015
ovulation cycle GO:0042698 9 0.014
spermatid differentiation GO:0048515 4 0.014
regulation of locomotion GO:0040012 329 0.014
regulation of viral process GO:0050792 103 0.014
anterior posterior axis specification GO:0009948 2 0.014
immune response GO:0006955 307 0.014
protein processing GO:0016485 226 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
negative regulation of cell cycle GO:0045786 193 0.014
regulation of protein localization GO:0032880 296 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
cell adhesion GO:0007155 325 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
membrane organization GO:0061024 292 0.014
blastoderm segmentation GO:0007350 2 0.014
oxidation reduction process GO:0055114 396 0.014
chromatin modification GO:0016568 298 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
oocyte development GO:0048599 1 0.013
intracellular protein transport GO:0006886 270 0.013
action potential GO:0001508 34 0.013
meiosis i GO:0007127 4 0.013
cell projection organization GO:0030030 252 0.013
carbohydrate metabolic process GO:0005975 207 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
chromatin organization GO:0006325 351 0.013
spermatid development GO:0007286 4 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of kinase activity GO:0043549 314 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
dna replication GO:0006260 116 0.013
axon ensheathment GO:0008366 6 0.013
reproductive system development GO:0061458 56 0.013
macromolecule methylation GO:0043414 97 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.013
regulation of protein kinase activity GO:0045859 289 0.013
microtubule based process GO:0007017 210 0.013
maintenance of location GO:0051235 112 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
negative regulation of cell cycle process GO:0010948 121 0.012
endomembrane system organization GO:0010256 196 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of intracellular transport GO:0032386 195 0.012
thymus development GO:0048538 3 0.012
cellular lipid metabolic process GO:0044255 303 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
hindbrain development GO:0030902 3 0.012
eye photoreceptor cell differentiation GO:0001754 2 0.012
secretion GO:0046903 254 0.012
mrna metabolic process GO:0016071 175 0.012
regulation of transferase activity GO:0051338 355 0.012
cell part morphogenesis GO:0032990 137 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
protein targeting GO:0006605 187 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
defense response GO:0006952 315 0.012
chemical homeostasis GO:0048878 306 0.012
regeneration GO:0031099 4 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
ovulation cycle process GO:0022602 9 0.012
tripartite regional subdivision GO:0007351 2 0.011
rna processing GO:0006396 255 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
circulatory system development GO:0072359 262 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
histone modification GO:0016570 251 0.011
organelle fission GO:0048285 149 0.011
regulation of multi organism process GO:0043900 157 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of cellular component movement GO:0051270 334 0.011
cell activation GO:0001775 213 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
gonad development GO:0008406 34 0.011
adult locomotory behavior GO:0008344 1 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
positive regulation of growth GO:0045927 58 0.011
Worm
phospholipid metabolic process GO:0006644 99 0.011
transcription from rna polymerase iii promoter GO:0006383 19 0.011
apoptotic signaling pathway GO:0097190 268 0.011
positive regulation of organelle organization GO:0010638 195 0.011
dna repair GO:0006281 198 0.011
cofactor metabolic process GO:0051186 87 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
rho protein signal transduction GO:0007266 26 0.011
ncrna processing GO:0034470 83 0.010
developmental programmed cell death GO:0010623 3 0.010
multicellular organismal reproductive process GO:0048609 40 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
cytokine production GO:0001816 247 0.010
lipid biosynthetic process GO:0008610 177 0.010
epithelium development GO:0060429 227 0.010
cell cell recognition GO:0009988 4 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
nerve development GO:0021675 4 0.010
nuclear transport GO:0051169 179 0.010
nuclear division GO:0000280 128 0.010
negative regulation of growth GO:0045926 97 0.010
ion transmembrane transport GO:0034220 338 0.010
autophagy GO:0006914 88 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
protein catabolic process GO:0030163 325 0.010
ion homeostasis GO:0050801 230 0.010
response to growth factor GO:0070848 205 0.010

EIF2B5 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.036
nervous system disease DOID:863 431 0.036
sensory system disease DOID:0050155 203 0.029
eye and adnexa disease DOID:1492 150 0.029
eye disease DOID:5614 149 0.029
neurodegenerative disease DOID:1289 102 0.023
disease of metabolism DOID:0014667 295 0.023
musculoskeletal system disease DOID:17 223 0.019
inherited metabolic disorder DOID:655 242 0.019
retinal disease DOID:5679 118 0.015
retinal degeneration DOID:8466 89 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
myopathy DOID:423 104 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
organ system cancer DOID:0050686 164 0.011