|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.926
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.899
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.884
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.884
|
Human Mouse Rat |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.884
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.866
|
Human |
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.838
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.834
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.829
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.812
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.811
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.810
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.806
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.776
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.771
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.759
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.739
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.714
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.710
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.708
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.708
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.703
|
Human |
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.703
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.692
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.690
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.684
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.681
|
Human Mouse Rat |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.677
|
Human |
|
|
chronic inflammatory response
|
GO:0002544 |
2 |
0.674
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.673
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.668
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.660
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.657
|
Human Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.653
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.641
|
|
|
|
positive regulation of interleukin 8 biosynthetic process
|
GO:0045416 |
8 |
0.622
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.618
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.615
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.614
|
Human |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.581
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.572
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.566
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.563
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.559
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.559
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.558
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.546
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.530
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.529
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.527
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.525
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.524
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.512
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.489
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.481
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.477
|
Human |
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.476
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.473
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.458
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.452
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.445
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.443
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.434
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.429
|
|
|
|
positive regulation of calcidiol 1 monooxygenase activity
|
GO:0060559 |
3 |
0.427
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.423
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.413
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.410
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.408
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.407
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.406
|
Human Mouse Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.391
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.391
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.389
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.387
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.384
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.383
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.383
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.380
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.380
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.379
|
Human |
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.375
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.371
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.370
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.370
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.368
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.365
|
Human Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.357
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.356
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.352
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.341
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.338
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.335
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.331
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.331
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.331
|
Human |
|
|
negative regulation of lipid catabolic process
|
GO:0050995 |
9 |
0.326
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.323
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.318
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.315
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.313
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.312
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.306
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.306
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.303
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.303
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.302
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.301
|
Human |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.299
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.296
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.291
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.291
|
|
|
|
positive regulation of heterotypic cell cell adhesion
|
GO:0034116 |
8 |
0.288
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.285
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.281
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.281
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.279
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.278
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.271
|
Human |
|
|
nuclear import
|
GO:0051170 |
106 |
0.271
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.270
|
Human |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.262
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.262
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.257
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.254
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.253
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.252
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.252
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.251
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.251
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.249
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.241
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.240
|
Human |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.240
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.239
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.236
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.234
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
4 |
0.233
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.226
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.226
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.217
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.217
|
Human |
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.216
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.215
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.212
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.211
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.210
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.210
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.209
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.208
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.206
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.203
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.203
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.203
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.203
|
|
|
|
positive regulation of steroid metabolic process
|
GO:0045940 |
13 |
0.201
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.200
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.199
|
Human |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.199
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.197
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.195
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.193
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.193
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.193
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.192
|
|
|
|
negative regulation of production of molecular mediator of immune response
|
GO:0002701 |
13 |
0.192
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.191
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.190
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.190
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.189
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.189
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.189
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.186
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.185
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.184
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.183
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.182
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.181
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.181
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.180
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.180
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.180
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
0.174
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.174
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.171
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.171
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.168
|
Human Mouse Rat |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.166
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.165
|
Human |
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.165
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.163
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.163
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
7 |
0.161
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.160
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.160
|
|
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.160
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.159
|
Human |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.159
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.158
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.154
|
|
|
|
positive regulation of vitamin d biosynthetic process
|
GO:0060557 |
3 |
0.154
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.153
|
Mouse |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.153
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.152
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.151
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.148
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.145
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.145
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.144
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.142
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.141
|
Human |
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.141
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.141
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.140
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.139
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.139
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.139
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.139
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.138
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.138
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.137
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.137
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.136
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.136
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.136
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.136
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.135
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.135
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.134
|
Human |
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.132
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.131
|
Human |
|
|
regulation of podosome assembly
|
GO:0071801 |
5 |
0.129
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.129
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.127
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.126
|
Human Rat |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.125
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.124
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.124
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.123
|
Human |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.122
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.121
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.121
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.121
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.120
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.118
|
Human |
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.118
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.118
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.117
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.117
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.116
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.114
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.113
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.112
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.111
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.111
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.109
|
Human |
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.109
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.109
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.108
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.107
|
Human |
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.104
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.104
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.103
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.103
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.102
|
Human |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.102
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.102
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.101
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.101
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.100
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.100
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.100
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.098
|
Human |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.097
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.097
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.094
|
Human |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.094
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.093
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.093
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.092
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.092
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.091
|
Human |
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.091
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
4 |
0.090
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.090
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.090
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.090
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.090
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.090
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.088
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.087
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.087
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.086
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.086
|
Human Mouse Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.085
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.084
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.082
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.082
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.081
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.080
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.080
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.079
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.079
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.079
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.079
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.079
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.079
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.079
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.078
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.078
|
|
|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
3 |
0.077
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.077
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.077
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.077
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.076
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.076
|
Mouse |
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.075
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.075
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.074
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.073
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.073
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.072
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.072
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.071
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.071
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.071
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.071
|
|
|
|
regulation of viral genome replication
|
GO:0045069 |
48 |
0.071
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.069
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.069
|
Mouse |
|
|
response to heat
|
GO:0009408 |
21 |
0.069
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.068
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.068
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.068
|
Human |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.068
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.068
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.068
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.068
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.068
|
Human |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.066
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.066
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.066
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.066
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.065
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.065
|
Human |
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.065
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.065
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.065
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.065
|
Human |
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.064
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.064
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.064
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.064
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.064
|
Human |
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.063
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.063
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
3 |
0.063
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.063
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.063
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.063
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.063
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.062
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.062
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.062
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.062
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.061
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.061
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.060
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.060
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.060
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.060
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.059
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.058
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.058
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.057
|
Human |
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.055
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.055
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.055
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.054
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.054
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.054
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.053
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.053
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.053
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.052
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.051
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.051
|
|
|
|
positive regulation of alcohol biosynthetic process
|
GO:1902932 |
9 |
0.051
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.051
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.051
|
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.051
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.050
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.050
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.049
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.049
|
Mouse |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.049
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
7 |
0.049
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.048
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.047
|
|
|
|
positive regulation of organelle assembly
|
GO:1902117 |
17 |
0.047
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.047
|
Human |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.047
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.047
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.047
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.046
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.046
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.046
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.046
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.045
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.045
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.045
|
Human |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.045
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.045
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.045
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.044
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.044
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.043
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.043
|
|
|
|
positive regulation of vitamin metabolic process
|
GO:0046136 |
3 |
0.043
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.042
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.042
|
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
4 |
0.042
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.042
|
|
|
|
sequestering of triglyceride
|
GO:0030730 |
11 |
0.041
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.041
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.041
|
Human |
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.041
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.040
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.040
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.040
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.040
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.040
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.040
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.040
|
Human |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.040
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.040
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.039
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.039
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.039
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.039
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.039
|
Human |
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.039
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.038
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.038
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.038
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.037
|
|
|
|
establishment of lymphocyte polarity
|
GO:0001767 |
2 |
0.037
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.037
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.037
|
Human |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.037
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.036
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.036
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.036
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.036
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.036
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.036
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.035
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.035
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.035
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.035
|
Mouse |
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.034
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.034
|
Human |
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.034
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.034
|
Human |
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.034
|
|
|
|
protein refolding
|
GO:0042026 |
14 |
0.034
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.034
|
Human |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.033
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.033
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.033
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.033
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.033
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.033
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.033
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.033
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.033
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.032
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.032
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.032
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.032
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.032
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.032
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
7 |
0.032
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.032
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.032
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.032
|
Human |
