Homo sapiens

176 known processes

EIF2B2

eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

(Aliases: EIF-2Bbeta,EIF2B)

EIF2B2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleotide catabolic process GO:0030813 185 0.634
post embryonic development GO:0009791 2 0.600
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.555
glycosyl compound catabolic process GO:1901658 413 0.511
trna splicing via endonucleolytic cleavage and ligation GO:0006388 7 0.500
ribonucleoside triphosphate metabolic process GO:0009199 412 0.492
positive regulation of nucleotide metabolic process GO:0045981 230 0.423
positive regulation of gtpase activity GO:0043547 166 0.420
ribonucleoside catabolic process GO:0042454 406 0.405
regulation of nucleotide catabolic process GO:0030811 205 0.403
nucleotide catabolic process GO:0009166 408 0.394
oligodendrocyte development GO:0014003 6 0.382
organophosphate catabolic process GO:0046434 430 0.378
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.376
gtp metabolic process GO:0046039 239 0.357
guanosine containing compound catabolic process GO:1901069 239 0.337
gtp catabolic process GO:0006184 237 0.322
nucleoside phosphate catabolic process GO:1901292 412 0.320
ribonucleotide catabolic process GO:0009261 405 0.301
positive regulation of gtp catabolic process GO:0033126 166 0.300
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.297
purine nucleoside triphosphate metabolic process GO:0009144 412 0.293
purine containing compound catabolic process GO:0072523 411 0.290
nucleoside triphosphate metabolic process GO:0009141 422 0.275
nucleoside catabolic process GO:0009164 408 0.275
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.273
regulation of nucleoside metabolic process GO:0009118 209 0.267
nucleoside triphosphate catabolic process GO:0009143 394 0.249
ribonucleoside triphosphate catabolic process GO:0009203 391 0.247
regulation of gtp catabolic process GO:0033124 180 0.246
guanosine containing compound metabolic process GO:1901068 244 0.244
trna processing GO:0008033 23 0.239
purine nucleotide catabolic process GO:0006195 405 0.233
translational initiation GO:0006413 48 0.213
positive regulation of nucleoside metabolic process GO:0045979 186 0.208
purine nucleoside catabolic process GO:0006152 398 0.178
regulation of purine nucleotide metabolic process GO:1900542 264 0.175
regulation of purine nucleotide catabolic process GO:0033121 205 0.174
translation GO:0006412 132 0.171
vesicle mediated transport GO:0016192 371 0.170
Worm
positive regulation of hydrolase activity GO:0051345 331 0.169
positive regulation of catabolic process GO:0009896 310 0.163
regulation of gtpase activity GO:0043087 180 0.162
cellular amino acid metabolic process GO:0006520 116 0.154
receptor mediated endocytosis GO:0006898 84 0.146
Worm
positive regulation of cellular catabolic process GO:0031331 284 0.128
trna metabolic process GO:0006399 35 0.115
posttranscriptional regulation of gene expression GO:0010608 213 0.110
regulation of nucleotide metabolic process GO:0006140 269 0.102
purine ribonucleoside metabolic process GO:0046128 437 0.097
purine nucleoside triphosphate catabolic process GO:0009146 392 0.094
transmission of nerve impulse GO:0019226 11 0.086
neurogenesis GO:0022008 169 0.083
atp catabolic process GO:0006200 157 0.080
rna splicing GO:0008380 131 0.079
regulation of membrane potential GO:0042391 95 0.072
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.064
rna processing GO:0006396 255 0.063
action potential GO:0001508 34 0.060
ncrna processing GO:0034470 83 0.059
endocytosis GO:0006897 159 0.057
Worm
purine containing compound biosynthetic process GO:0072522 88 0.056
embryo development GO:0009790 123 0.053
Worm
ncrna metabolic process GO:0034660 108 0.050
neuronal action potential GO:0019228 9 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
nervous system development GO:0007399 293 0.047
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
negative regulation of protein metabolic process GO:0051248 391 0.046
purine ribonucleotide biosynthetic process GO:0009152 79 0.039
response to abiotic stimulus GO:0009628 336 0.039
Rat
regulation of translational initiation GO:0006446 24 0.037
single organism reproductive process GO:0044702 98 0.037
ribonucleoside monophosphate metabolic process GO:0009161 187 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
nucleoside monophosphate catabolic process GO:0009125 159 0.034
locomotory behavior GO:0007626 1 0.034
cytoplasmic transport GO:0016482 379 0.032
oogenesis GO:0048477 2 0.032
response to biotic stimulus GO:0009607 276 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
n terminal protein amino acid modification GO:0031365 13 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
cell development GO:0048468 328 0.030
neurological system process GO:0050877 163 0.030
blastocyst development GO:0001824 3 0.030
positive regulation of cellular component organization GO:0051130 376 0.029
growth GO:0040007 202 0.029
Worm
amine metabolic process GO:0009308 44 0.028
cellular response to endogenous stimulus GO:0071495 336 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
single organism membrane organization GO:0044802 268 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
protein acylation GO:0043543 138 0.026
positive regulation of developmental process GO:0051094 314 0.026
Worm
oligodendrocyte differentiation GO:0048709 7 0.026
reproductive structure development GO:0048608 55 0.026
toxin transport GO:1901998 4 0.026
mitotic cell cycle process GO:1903047 286 0.025
purine nucleoside monophosphate metabolic process GO:0009126 186 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
embryonic eye morphogenesis GO:0048048 2 0.023
amino acid activation GO:0043038 12 0.023
dephosphorylation GO:0016311 209 0.023
cell cell recognition GO:0009988 4 0.023
protein localization to organelle GO:0033365 280 0.022
cell projection organization GO:0030030 252 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
trna aminoacylation for protein translation GO:0006418 8 0.021
reproductive process GO:0022414 106 0.021
rna interference GO:0016246 4 0.021
regulation of immune response GO:0050776 201 0.021
macromolecule methylation GO:0043414 97 0.021
rna splicing via endonucleolytic cleavage and ligation GO:0000394 8 0.021
cellular component morphogenesis GO:0032989 314 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
mitotic cell cycle GO:0000278 326 0.020
regulation of transcription during mitosis GO:0045896 2 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
regulation of cellular response to stress GO:0080135 244 0.020
immune response GO:0006955 307 0.019
sex differentiation GO:0007548 45 0.019
atp metabolic process GO:0046034 176 0.018
cell morphogenesis GO:0000902 296 0.018
dna repair GO:0006281 198 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
cellular amine metabolic process GO:0044106 41 0.018
lipoprotein metabolic process GO:0042157 42 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
female gonad development GO:0008585 10 0.018
cellular protein catabolic process GO:0044257 261 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
adult locomotory behavior GO:0008344 1 0.017
purine ribonucleoside biosynthetic process GO:0046129 23 0.017
ribose phosphate biosynthetic process GO:0046390 82 0.017
negative regulation of protein modification process GO:0031400 200 0.017
neuromuscular junction development GO:0007528 3 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
regulation of cell differentiation GO:0045595 393 0.017
female gamete generation GO:0007292 2 0.016
regulation of growth GO:0040008 165 0.016
Worm
regulation of cell cycle GO:0051726 393 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
reproduction GO:0000003 63 0.016
regulation of cell cycle process GO:0010564 266 0.016
response to other organism GO:0051707 261 0.016
secretion GO:0046903 254 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
oocyte differentiation GO:0009994 2 0.016
divalent inorganic cation transport GO:0072511 158 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of translation GO:0006417 89 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
mitochondrial translation GO:0032543 17 0.015
biological adhesion GO:0022610 331 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
multicellular organismal aging GO:0010259 3 0.015
cell adhesion GO:0007155 325 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
calcium ion transport GO:0006816 147 0.015
multicellular organism reproduction GO:0032504 42 0.015
positive regulation of transport GO:0051050 336 0.015
cell division GO:0051301 168 0.015
eye photoreceptor cell differentiation GO:0001754 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.014
cytokine production GO:0001816 247 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
cell cycle phase transition GO:0044770 173 0.014
negative regulation of developmental process GO:0051093 247 0.014
intracellular protein transport GO:0006886 270 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
hindbrain development GO:0030902 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
protein maturation GO:0051604 233 0.014
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.014
ovulation cycle GO:0042698 9 0.014
organelle assembly GO:0070925 176 0.014
embryo development ending in birth or egg hatching GO:0009792 34 0.014
Worm
regulation of dna metabolic process GO:0051052 153 0.014
positive regulation of immune system process GO:0002684 283 0.013
glial cell development GO:0021782 7 0.013
trna aminoacylation GO:0043039 12 0.013
dna dealkylation GO:0035510 13 0.013
regulation of protein stability GO:0031647 87 0.013
oocyte development GO:0048599 1 0.013
positive regulation of immune response GO:0050778 159 0.013
protein polymerization GO:0051258 71 0.013
nerve development GO:0021675 4 0.013
defense response GO:0006952 315 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
cell projection morphogenesis GO:0048858 129 0.012
neuron development GO:0048666 113 0.012
developmental programmed cell death GO:0010623 3 0.012
mitotic nuclear division GO:0007067 119 0.012
regulation of mitosis GO:0007088 63 0.012
response to cytokine GO:0034097 232 0.012
generation of neurons GO:0048699 152 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
system process GO:0003008 349 0.012
regulation of protein maturation GO:1903317 150 0.012
segmentation GO:0035282 4 0.012
actin filament based process GO:0030029 224 0.012
sperm egg recognition GO:0035036 3 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
retina layer formation GO:0010842 3 0.012
cellular lipid metabolic process GO:0044255 303 0.012
methylation GO:0032259 106 0.012
positive regulation of growth GO:0045927 58 0.012
Worm
cellular response to cytokine stimulus GO:0071345 181 0.012
spermatid development GO:0007286 4 0.012
response to drug GO:0042493 81 0.012
carbohydrate metabolic process GO:0005975 207 0.011
multicellular organismal signaling GO:0035637 34 0.011
regulation of protein localization GO:0032880 296 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
protein oligomerization GO:0051259 173 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of locomotion GO:0040012 329 0.011
peripheral nervous system development GO:0007422 2 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
epithelium development GO:0060429 227 0.011
single organism cellular localization GO:1902580 332 0.011
cellular protein complex assembly GO:0043623 188 0.011
response to external biotic stimulus GO:0043207 261 0.011
metal ion transport GO:0030001 272 0.011
spermatid differentiation GO:0048515 4 0.011
protein catabolic process GO:0030163 325 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
regulation of rna splicing GO:0043484 62 0.011
epithelial cell differentiation GO:0030855 141 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
innate immune response GO:0045087 178 0.011
gliogenesis GO:0042063 21 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
secretion by cell GO:0032940 226 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
chordate embryonic development GO:0043009 34 0.010
cellular ion homeostasis GO:0006873 168 0.010
double strand break repair GO:0006302 101 0.010
positive regulation of dna metabolic process GO:0051054 73 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
protein processing GO:0016485 226 0.010
regulation of intracellular transport GO:0032386 195 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.010
microtubule polymerization or depolymerization GO:0031109 37 0.010
wnt signaling pathway GO:0016055 156 0.010
membrane hyperpolarization GO:0060081 1 0.010
negative regulation of cell growth GO:0030308 83 0.010
regulation of proteolysis GO:0030162 293 0.010
response to lipid GO:0033993 206 0.010

EIF2B2 disease predictions

Disease DO term ID Size Probability Func Analog Org
usher syndrome DOID:0050439 12 0.033
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
immune system disease DOID:2914 155 0.010