Homo sapiens

151 known processes

HPRT1

hypoxanthine phosphoribosyltransferase 1

(Aliases: HPRT,HGPRT)

HPRT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.283
organonitrogen compound biosynthetic process GO:1901566 200 0.207
urate metabolic process GO:0046415 11 0.118
positive regulation of programmed cell death GO:0043068 249 0.115
oocyte differentiation GO:0009994 2 0.103
nucleotide biosynthetic process GO:0009165 109 0.102
mesenchymal cell development GO:0014031 50 0.097
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.083
small molecule biosynthetic process GO:0044283 157 0.076
spermatid development GO:0007286 4 0.069
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.066
dna recombination GO:0006310 77 0.065
cellular amino acid metabolic process GO:0006520 116 0.065
regulation of peptidase activity GO:0052547 180 0.064
detection of stimulus GO:0051606 85 0.063
positive regulation of hydrolase activity GO:0051345 331 0.061
positive regulation of cell differentiation GO:0045597 211 0.056
positive regulation of immune system process GO:0002684 283 0.052
response to oxidative stress GO:0006979 121 0.052
response to steroid hormone GO:0048545 80 0.050
endomembrane system organization GO:0010256 196 0.049
carbohydrate metabolic process GO:0005975 207 0.049
single organism carbohydrate metabolic process GO:0044723 193 0.048
positive regulation of phosphorylation GO:0042327 394 0.047
locomotory behavior GO:0007626 1 0.047
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
cellular response to dna damage stimulus GO:0006974 379 0.042
determination of adult lifespan GO:0008340 2 0.041
oocyte development GO:0048599 1 0.040
organophosphate biosynthetic process GO:0090407 163 0.039
nucleoside phosphate biosynthetic process GO:1901293 109 0.039
regulation of endopeptidase activity GO:0052548 170 0.039
alpha amino acid biosynthetic process GO:1901607 23 0.037
regulation of proteolysis GO:0030162 293 0.036
cellular response to growth factor stimulus GO:0071363 197 0.035
nucleocytoplasmic transport GO:0006913 176 0.034
meiosis i GO:0007127 4 0.034
purine containing compound biosynthetic process GO:0072522 88 0.033
ras protein signal transduction GO:0007265 73 0.032
cellular lipid metabolic process GO:0044255 303 0.032
nuclear export GO:0051168 69 0.032
negative regulation of protein metabolic process GO:0051248 391 0.031
neurological system process GO:0050877 163 0.031
microtubule based process GO:0007017 210 0.031
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.031
spermatid differentiation GO:0048515 4 0.031
regulation of ion transmembrane transport GO:0034765 132 0.030
negative regulation of apoptotic process GO:0043066 316 0.030
positive regulation of cell death GO:0010942 263 0.030
regulation of transmembrane transport GO:0034762 139 0.030
post embryonic development GO:0009791 2 0.030
regeneration GO:0031099 4 0.029
single organism cellular localization GO:1902580 332 0.029
lung saccule development GO:0060430 2 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
epithelial to mesenchymal transition GO:0001837 48 0.029
positive regulation of apoptotic process GO:0043065 246 0.028
positive regulation of peptidase activity GO:0010952 88 0.028
lipid metabolic process GO:0006629 381 0.028
sulfur compound metabolic process GO:0006790 101 0.028
protein processing GO:0016485 226 0.028
cellular component disassembly GO:0022411 92 0.027
nuclear transport GO:0051169 179 0.027
nervous system development GO:0007399 293 0.027
Mouse Rat
response to abiotic stimulus GO:0009628 336 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
response to other organism GO:0051707 261 0.027
glycoprotein metabolic process GO:0009100 110 0.026
oocyte maturation GO:0001556 1 0.026
nitrogen compound transport GO:0071705 191 0.024
regulation of cell cycle GO:0051726 393 0.024
female gamete generation GO:0007292 2 0.024
positive regulation of transport GO:0051050 336 0.024
response to activity GO:0014823 0 0.023
glycoprotein biosynthetic process GO:0009101 91 0.023
dna catabolic process GO:0006308 49 0.023
endocytosis GO:0006897 159 0.023
organic acid biosynthetic process GO:0016053 97 0.023
regulation of cytoplasmic transport GO:1903649 149 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
fatty acid biosynthetic process GO:0006633 46 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
divalent inorganic cation transport GO:0072511 158 0.022
sensory perception of pain GO:0019233 4 0.022
protein oligomerization GO:0051259 173 0.022
positive regulation of transferase activity GO:0051347 227 0.022
regulation of intracellular transport GO:0032386 195 0.022
activation of cysteine type endopeptidase activity GO:0097202 57 0.022
signal transduction by phosphorylation GO:0023014 297 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
multicellular organismal aging GO:0010259 3 0.021
reproduction GO:0000003 63 0.020
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
adult locomotory behavior GO:0008344 1 0.020
epithelium development GO:0060429 227 0.020
rna transport GO:0050658 39 0.020
protein ubiquitination GO:0016567 314 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
oogenesis GO:0048477 2 0.020
positive regulation of cytoplasmic transport GO:1903651 82 0.019
amine metabolic process GO:0009308 44 0.019
microtubule organizing center organization GO:0031023 62 0.019
meiotic chromosome segregation GO:0045132 4 0.019
calcium ion transport GO:0006816 147 0.019
intracellular protein transport GO:0006886 270 0.019
cell morphogenesis GO:0000902 296 0.019
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
regulation of binding GO:0051098 111 0.018
fatty acid derivative metabolic process GO:1901568 35 0.018
embryo development GO:0009790 123 0.018
protein localization to organelle GO:0033365 280 0.018
response to hormone GO:0009725 175 0.018
Rat
cellular ketone metabolic process GO:0042180 80 0.018
apoptotic signaling pathway GO:0097190 268 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
cell development GO:0048468 328 0.018
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
cellular response to oxidative stress GO:0034599 85 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
negative regulation of cell death GO:0060548 345 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
positive regulation of proteolysis GO:0045862 142 0.016
nuclear import GO:0051170 106 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
pharynx development GO:0060465 1 0.016
sulfur compound biosynthetic process GO:0044272 38 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
protein maturation GO:0051604 233 0.016
golgi organization GO:0007030 38 0.016
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.016
regulation of cellular response to stress GO:0080135 244 0.016
positive regulation of endopeptidase activity GO:0010950 84 0.016
regulation of multi organism process GO:0043900 157 0.016
chemotaxis GO:0006935 157 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
regulation of ion transport GO:0043269 189 0.015
alpha amino acid metabolic process GO:1901605 72 0.015
cation transport GO:0006812 331 0.015
chromatin modification GO:0016568 298 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
negative regulation of transferase activity GO:0051348 124 0.015
response to mechanical stimulus GO:0009612 51 0.015
vesicle mediated transport GO:0016192 371 0.015
regulation of locomotion GO:0040012 329 0.015
nucleoside biosynthetic process GO:0009163 26 0.015
regulation of kinase activity GO:0043549 314 0.014
cell fate specification GO:0001708 8 0.014
recombinational repair GO:0000725 50 0.014
purine ribonucleoside biosynthetic process GO:0046129 23 0.014
rna processing GO:0006396 255 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
fatty acid metabolic process GO:0006631 115 0.014
protein localization to nucleus GO:0034504 136 0.014
mapk cascade GO:0000165 288 0.014
immune response GO:0006955 307 0.014
system process GO:0003008 349 0.014
ion transmembrane transport GO:0034220 338 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
negative regulation of protein modification process GO:0031400 200 0.013
hemopoiesis GO:0030097 180 0.013
covalent chromatin modification GO:0016569 254 0.013
mrna processing GO:0006397 133 0.013
regulation of protein localization GO:0032880 296 0.013
cellular amine metabolic process GO:0044106 41 0.013
divalent metal ion transport GO:0070838 152 0.013
nucleobase containing compound transport GO:0015931 51 0.013
regulation of membrane potential GO:0042391 95 0.013
chromosome segregation GO:0007059 114 0.013
dna repair GO:0006281 198 0.013
nucleus organization GO:0006997 28 0.013
response to lipopolysaccharide GO:0032496 70 0.012
single organism nuclear import GO:1902593 104 0.012
response to wounding GO:0009611 168 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
mesenchymal cell differentiation GO:0048762 52 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.012
neuron differentiation GO:0030182 138 0.012
Mouse
autophagy GO:0006914 88 0.012
response to axon injury GO:0048678 1 0.012
cellular component morphogenesis GO:0032989 314 0.012
Mouse
innate immune response GO:0045087 178 0.012
defense response GO:0006952 315 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
response to growth factor GO:0070848 205 0.012
protein targeting to nucleus GO:0044744 104 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
unsaturated fatty acid metabolic process GO:0033559 37 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
positive regulation of developmental process GO:0051094 314 0.011
response to radiation GO:0009314 151 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
protein alkylation GO:0008213 74 0.011
chordate embryonic development GO:0043009 34 0.011
regulation of protein transport GO:0051223 213 0.011
mitotic cell cycle process GO:1903047 286 0.011
leukocyte activation GO:0045321 164 0.011
Mouse
cell cell signaling GO:0007267 155 0.011
single organism membrane organization GO:0044802 268 0.011
regulation of meiosis GO:0040020 3 0.011
response to organic cyclic compound GO:0014070 204 0.011
macromolecule methylation GO:0043414 97 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
ribonucleotide biosynthetic process GO:0009260 81 0.011
icosanoid biosynthetic process GO:0046456 18 0.011
zymogen activation GO:0031638 70 0.010
protein export from nucleus GO:0006611 29 0.010
response to decreased oxygen levels GO:0036293 96 0.010
protein methylation GO:0006479 74 0.010
nuclear division GO:0000280 128 0.010
positive regulation of intracellular protein transport GO:0090316 76 0.010
blastocyst development GO:0001824 3 0.010
microtubule based movement GO:0007018 32 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
membrane organization GO:0061024 292 0.010

HPRT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.153
inherited metabolic disorder DOID:655 242 0.079
immune system disease DOID:2914 155 0.013
disease of mental health DOID:150 70 0.011