Homo sapiens

84 known processes

NUDT18

nudix (nucleoside diphosphate linked moiety X)-type motif 18

(Aliases: FLJ22494)

NUDT18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rab protein signal transduction GO:0032482 4 0.989
positive regulation of rab gtpase activity GO:0032851 39 0.978
regulation of rab gtpase activity GO:0032313 39 0.963
regulation of rab protein signal transduction GO:0032483 39 0.884
purine nucleotide catabolic process GO:0006195 405 0.604
small gtpase mediated signal transduction GO:0007264 78 0.547
ribonucleotide catabolic process GO:0009261 405 0.503
guanosine containing compound metabolic process GO:1901068 244 0.450
cilium morphogenesis GO:0060271 75 0.434
glycosyl compound catabolic process GO:1901658 413 0.395
cilium assembly GO:0042384 63 0.370
nucleotide catabolic process GO:0009166 408 0.367
ribonucleoside catabolic process GO:0042454 406 0.335
positive regulation of gtp catabolic process GO:0033126 166 0.329
purine nucleoside catabolic process GO:0006152 398 0.323
ras protein signal transduction GO:0007265 73 0.318
cilium organization GO:0044782 68 0.290
nucleoside triphosphate metabolic process GO:0009141 422 0.266
regulation of gtpase activity GO:0043087 180 0.260
sulfur compound metabolic process GO:0006790 101 0.253
purine ribonucleotide catabolic process GO:0009154 404 0.250
purine nucleoside triphosphate metabolic process GO:0009144 412 0.244
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.224
organophosphate catabolic process GO:0046434 430 0.223
purine containing compound catabolic process GO:0072523 411 0.222
nucleoside catabolic process GO:0009164 408 0.221
regulation of nucleotide catabolic process GO:0030811 205 0.215
nucleoside phosphate catabolic process GO:1901292 412 0.196
regulation of gtp catabolic process GO:0033124 180 0.188
guanosine containing compound catabolic process GO:1901069 239 0.175
regulation of nucleoside metabolic process GO:0009118 209 0.174
regulation of purine nucleotide catabolic process GO:0033121 205 0.166
regulation of small gtpase mediated signal transduction GO:0051056 156 0.158
cell projection assembly GO:0030031 126 0.155
positive regulation of nucleoside metabolic process GO:0045979 186 0.145
positive regulation of nucleotide metabolic process GO:0045981 230 0.140
positive regulation of gtpase activity GO:0043547 166 0.136
positive regulation of hydrolase activity GO:0051345 331 0.135
purine ribonucleoside metabolic process GO:0046128 437 0.133
regulation of ras protein signal transduction GO:0046578 155 0.133
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.130
positive regulation of ras gtpase activity GO:0032320 117 0.127
organelle assembly GO:0070925 176 0.125
nucleoside triphosphate catabolic process GO:0009143 394 0.124
purine ribonucleoside catabolic process GO:0046130 398 0.121
ribonucleoside triphosphate metabolic process GO:0009199 412 0.116
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.116
cellular amino acid metabolic process GO:0006520 116 0.115
gtp metabolic process GO:0046039 239 0.110
endosomal transport GO:0016197 129 0.109
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.109
regulation of purine nucleotide metabolic process GO:1900542 264 0.109
positive regulation of catabolic process GO:0009896 310 0.106
regulation of ras gtpase activity GO:0032318 128 0.103
cell projection organization GO:0030030 252 0.098
ribonucleoside triphosphate catabolic process GO:0009203 391 0.098
positive regulation of cellular catabolic process GO:0031331 284 0.089
purine nucleoside triphosphate catabolic process GO:0009146 392 0.076
protein catabolic process GO:0030163 325 0.067
cellular amino acid biosynthetic process GO:0008652 30 0.063
positive regulation of nucleotide catabolic process GO:0030813 185 0.062
cell morphogenesis GO:0000902 296 0.061
protein localization to organelle GO:0033365 280 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.060
gtp catabolic process GO:0006184 237 0.059
regulation of protein localization GO:0032880 296 0.059
response to other organism GO:0051707 261 0.057
retrograde transport endosome to golgi GO:0042147 45 0.053
regulation of locomotion GO:0040012 329 0.052
cell projection morphogenesis GO:0048858 129 0.051
vesicle mediated transport GO:0016192 371 0.051
organonitrogen compound biosynthetic process GO:1901566 200 0.049
interspecies interaction between organisms GO:0044419 156 0.049
cellular response to nitrogen compound GO:1901699 144 0.048
viral process GO:0016032 146 0.048
cytoplasmic transport GO:0016482 379 0.048
cellular component morphogenesis GO:0032989 314 0.048
ubiquitin dependent protein catabolic process GO:0006511 206 0.047
regulation of organelle assembly GO:1902115 40 0.047
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.047
cellular macromolecule catabolic process GO:0044265 380 0.046
anatomical structure formation involved in morphogenesis GO:0048646 284 0.046
establishment of protein localization to membrane GO:0090150 121 0.046
regulation of cell motility GO:2000145 299 0.044
immune effector process GO:0002252 159 0.043
regulation of cell migration GO:0030334 289 0.043
immune response GO:0006955 307 0.043
regulation of cellular component movement GO:0051270 334 0.041
single organism membrane organization GO:0044802 268 0.041
protein localization to membrane GO:0072657 160 0.039
cellular response to endogenous stimulus GO:0071495 336 0.037
golgi vesicle transport GO:0048193 80 0.037
steroid catabolic process GO:0006706 10 0.037
regulation of defense response GO:0031347 154 0.036
cell part morphogenesis GO:0032990 137 0.036
viral life cycle GO:0019058 132 0.036
regulation of multi organism process GO:0043900 157 0.035
negative regulation of cilium assembly GO:1902018 3 0.034
defense response GO:0006952 315 0.034
phototransduction visible light GO:0007603 2 0.033
defense response to other organism GO:0098542 129 0.033
spermatid development GO:0007286 4 0.032
negative regulation of cellular component organization GO:0051129 235 0.031
modification dependent protein catabolic process GO:0019941 209 0.031
spermatid differentiation GO:0048515 4 0.029
response to oxygen containing compound GO:1901700 369 0.029
regulation of response to external stimulus GO:0032101 222 0.029
neuromuscular junction development GO:0007528 3 0.029
protein ubiquitination GO:0016567 314 0.029
intracellular protein transport GO:0006886 270 0.028
single organism cellular localization GO:1902580 332 0.028
regulation of cilium assembly GO:1902017 6 0.028
response to biotic stimulus GO:0009607 276 0.027
membrane organization GO:0061024 292 0.027
sulfur compound biosynthetic process GO:0044272 38 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
cellular modified amino acid metabolic process GO:0006575 64 0.026
carboxylic acid biosynthetic process GO:0046394 97 0.026
protein targeting GO:0006605 187 0.026
organic acid biosynthetic process GO:0016053 97 0.026
oocyte development GO:0048599 1 0.026
g protein coupled receptor signaling pathway GO:0007186 207 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
nucleoside monophosphate metabolic process GO:0009123 191 0.025
hair follicle morphogenesis GO:0031069 2 0.025
positive regulation of immune system process GO:0002684 283 0.025
negative regulation of developmental process GO:0051093 247 0.025
negative regulation of organelle organization GO:0010639 126 0.025
cellular component assembly involved in morphogenesis GO:0010927 73 0.025
coenzyme metabolic process GO:0006732 65 0.025
cellular protein catabolic process GO:0044257 261 0.024
response to nitrogen compound GO:1901698 184 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
multi organism cellular process GO:0044764 156 0.024
positive regulation of transport GO:0051050 336 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
keratinization GO:0031424 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
positive regulation of immune response GO:0050778 159 0.023
regulation of response to biotic stimulus GO:0002831 55 0.022
protein targeting to membrane GO:0006612 42 0.022
post embryonic development GO:0009791 2 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
cellular response to hormone stimulus GO:0032870 125 0.021
circadian behavior GO:0048512 2 0.021
cellular response to organonitrogen compound GO:0071417 124 0.021
positive regulation of neural precursor cell proliferation GO:2000179 2 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
protein oligomerization GO:0051259 173 0.021
nitrogen compound transport GO:0071705 191 0.021
memory GO:0007613 3 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
regulation of cell projection assembly GO:0060491 47 0.020
oocyte differentiation GO:0009994 2 0.020
phototransduction GO:0007602 3 0.020
segmentation GO:0035282 4 0.020
locomotory behavior GO:0007626 1 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
rho protein signal transduction GO:0007266 26 0.019
response to virus GO:0009615 126 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
response to radiation GO:0009314 151 0.019
actin cytoskeleton organization GO:0030036 207 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.018
activation of immune response GO:0002253 114 0.018
oogenesis GO:0048477 2 0.018
small molecule biosynthetic process GO:0044283 157 0.017
dephosphorylation GO:0016311 209 0.017
alpha amino acid metabolic process GO:1901605 72 0.017
ncrna metabolic process GO:0034660 108 0.017
cellular ketone metabolic process GO:0042180 80 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
response to nitric oxide GO:0071731 4 0.017
stem cell division GO:0017145 2 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
regulation of defense response to virus GO:0050688 33 0.017
rhodopsin mediated signaling pathway GO:0016056 1 0.016
translation GO:0006412 132 0.016
actin filament based process GO:0030029 224 0.016
er to golgi vesicle mediated transport GO:0006888 19 0.016
regulation of immune effector process GO:0002697 91 0.016
negative regulation of multi organism process GO:0043901 92 0.016
blastoderm segmentation GO:0007350 2 0.015
central nervous system development GO:0007417 123 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
regulation of translation GO:0006417 89 0.015
protein modification by small protein removal GO:0070646 92 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of cell projection organization GO:0031344 107 0.015
negative regulation of protein modification process GO:0031400 200 0.015
steroid metabolic process GO:0008202 94 0.015
positive regulation of viral process GO:0048524 37 0.014
nuclear transport GO:0051169 179 0.014
response to external biotic stimulus GO:0043207 261 0.014
negative regulation of response to external stimulus GO:0032102 83 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
cofactor metabolic process GO:0051186 87 0.014
regeneration GO:0031099 4 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
lipid metabolic process GO:0006629 381 0.014
viral gene expression GO:0019080 35 0.014
response to nutrient levels GO:0031667 81 0.014
defense response to virus GO:0051607 71 0.014
regulation of viral process GO:0050792 103 0.014
immune response activating signal transduction GO:0002757 90 0.014
response to oxidative stress GO:0006979 121 0.014
neuronal stem cell division GO:0036445 1 0.014
chromatin organization GO:0006325 351 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
anion transport GO:0006820 161 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
autophagy GO:0006914 88 0.013
cellular amine metabolic process GO:0044106 41 0.013
negative regulation of cell death GO:0060548 345 0.013
asymmetric neuroblast division GO:0055059 1 0.013
cellular protein complex assembly GO:0043623 188 0.013
associative learning GO:0008306 1 0.013
regulation of behavior GO:0050795 82 0.013
cellular response to external stimulus GO:0071496 111 0.013
regulation of immune response GO:0050776 201 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
multicellular organismal aging GO:0010259 3 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
regulation of secretion by cell GO:1903530 177 0.013
cellular response to nutrient levels GO:0031669 69 0.013
negative regulation of defense response GO:0031348 47 0.013
response to hormone GO:0009725 175 0.013
positive regulation of cytokine production GO:0001819 167 0.013
exocytosis GO:0006887 71 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
determination of adult lifespan GO:0008340 2 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cellular response to starvation GO:0009267 58 0.012
response to starvation GO:0042594 59 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
somatic stem cell division GO:0048103 1 0.012
negative regulation of immune system process GO:0002683 136 0.012
female gamete generation GO:0007292 2 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
renal water homeostasis GO:0003091 4 0.012
regulation of cytokine production GO:0001817 232 0.012
compound eye development GO:0048749 1 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
response to organic cyclic compound GO:0014070 204 0.012
amine metabolic process GO:0009308 44 0.012
negative regulation of organelle assembly GO:1902116 7 0.012
regulation of proteolysis GO:0030162 293 0.012
mitotic cell cycle process GO:1903047 286 0.012
negative regulation of cell projection organization GO:0031345 22 0.012
hindbrain development GO:0030902 3 0.012
regulation of rhodopsin mediated signaling pathway GO:0022400 1 0.012
sensory perception GO:0007600 103 0.012
chromatin modification GO:0016568 298 0.012
epidermis morphogenesis GO:0048730 3 0.012
cellular response to oxidative stress GO:0034599 85 0.012
leukocyte migration GO:0050900 107 0.012
detection of stimulus GO:0051606 85 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
positive regulation of digestive system process GO:0060456 2 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
innate immune response GO:0045087 178 0.011
visual behavior GO:0007632 2 0.011
inner ear morphogenesis GO:0042472 4 0.011
sleep GO:0030431 2 0.011
response to insulin GO:0032868 45 0.011
response to inorganic substance GO:0010035 127 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
mating GO:0007618 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.011
regulation of protein transport GO:0051223 213 0.011
small molecule catabolic process GO:0044282 92 0.011
adult locomotory behavior GO:0008344 1 0.011
response to fungus GO:0009620 4 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
response to axon injury GO:0048678 1 0.011
neurotransmitter secretion GO:0007269 4 0.011
negative regulation of leukocyte degranulation GO:0043301 1 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
secretion by cell GO:0032940 226 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
secretion GO:0046903 254 0.010
cellular cation homeostasis GO:0030003 163 0.010
negative regulation of transport GO:0051051 176 0.010
protein processing GO:0016485 226 0.010
metencephalon development GO:0022037 2 0.010
regulation of viral genome replication GO:0045069 48 0.010
regulation of hormone levels GO:0010817 125 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
regulation of cell cycle process GO:0010564 266 0.010
golgi to plasma membrane cftr protein transport GO:0043000 1 0.010
positive regulation of ion transport GO:0043270 87 0.010
anterior posterior axis specification GO:0009948 2 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
multicellular organismal homeostasis GO:0048871 67 0.010
circadian sleep wake cycle sleep GO:0050802 2 0.010
covalent chromatin modification GO:0016569 254 0.010
cellular response to radiation GO:0071478 65 0.010
negative regulation of immune effector process GO:0002698 38 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010

NUDT18 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.020
central nervous system disease DOID:331 186 0.020
disease of cellular proliferation DOID:14566 174 0.018
immune system disease DOID:2914 155 0.017
musculoskeletal system disease DOID:17 223 0.015
connective tissue disease DOID:65 109 0.015
sensory system disease DOID:0050155 203 0.014
bone disease DOID:0080001 88 0.011
disease of mental health DOID:150 70 0.011
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.011
eye and adnexa disease DOID:1492 150 0.010
eye disease DOID:5614 149 0.010