Homo sapiens

43 known processes

MARK4

MAP/microtubule affinity-regulating kinase 4

(Aliases: FLJ90097,KIAA1860,MARKL1L,MARK4S,FLJ12177,MARKL1,MARK4L)

MARK4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric neuroblast division GO:0055059 1 0.432
Worm
cellular ketone metabolic process GO:0042180 80 0.319
regulation of cellular ketone metabolic process GO:0010565 50 0.299
neuroblast division GO:0055057 1 0.248
Worm
positive regulation of cellular amine metabolic process GO:0033240 7 0.199
cell development GO:0048468 328 0.197
Human
somatic stem cell division GO:0048103 1 0.178
Worm
post embryonic development GO:0009791 2 0.175
Worm
small gtpase mediated signal transduction GO:0007264 78 0.173
regulation of cellular amine metabolic process GO:0033238 11 0.173
purine nucleotide catabolic process GO:0006195 405 0.156
microtubule cytoskeleton organization GO:0000226 176 0.138
cellular response to endogenous stimulus GO:0071495 336 0.138
asymmetric stem cell division GO:0098722 1 0.136
Worm
stem cell division GO:0017145 2 0.135
Worm
cell projection organization GO:0030030 252 0.126
Human
single organism cellular localization GO:1902580 332 0.119
nervous system development GO:0007399 293 0.116
neuronal stem cell division GO:0036445 1 0.115
Worm
ras protein signal transduction GO:0007265 73 0.114
cellular component morphogenesis GO:0032989 314 0.114
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.108
rho protein signal transduction GO:0007266 26 0.106
peptidyl serine phosphorylation GO:0018105 101 0.099
Worm
cell fate determination GO:0001709 3 0.098
Worm
regulation of nucleotide catabolic process GO:0030811 205 0.098
neuroblast proliferation GO:0007405 4 0.096
Worm
oogenesis GO:0048477 2 0.095
cell morphogenesis GO:0000902 296 0.092
Human
cellular response to growth factor stimulus GO:0071363 197 0.087
apoptotic signaling pathway GO:0097190 268 0.087
ribonucleoside catabolic process GO:0042454 406 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.086
regulation of cell morphogenesis GO:0022604 153 0.086
Human
determination of adult lifespan GO:0008340 2 0.085
positive regulation of gtpase activity GO:0043547 166 0.085
purine nucleoside catabolic process GO:0006152 398 0.084
multicellular organismal aging GO:0010259 3 0.084
cell projection morphogenesis GO:0048858 129 0.083
Human
positive regulation of hydrolase activity GO:0051345 331 0.083
cellular amino acid metabolic process GO:0006520 116 0.082
positive regulation of catabolic process GO:0009896 310 0.078
hindbrain development GO:0030902 3 0.076
regulation of cellular amino acid metabolic process GO:0006521 6 0.075
neuromuscular junction development GO:0007528 3 0.075
gtp metabolic process GO:0046039 239 0.071
regulation of cell differentiation GO:0045595 393 0.070
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.070
female gamete generation GO:0007292 2 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.068
purine ribonucleoside catabolic process GO:0046130 398 0.068
amine metabolic process GO:0009308 44 0.068
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.067
neuron differentiation GO:0030182 138 0.066
Human
protein autophosphorylation GO:0046777 123 0.066
Human
actin filament based process GO:0030029 224 0.065
regulation of purine nucleotide metabolic process GO:1900542 264 0.063
membrane organization GO:0061024 292 0.062
generation of neurons GO:0048699 152 0.061
Human Worm
response to oxygen containing compound GO:1901700 369 0.061
microtubule based process GO:0007017 210 0.060
positive regulation of cell development GO:0010720 92 0.060
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.059
mitotic cell cycle process GO:1903047 286 0.059
regulation of gtpase activity GO:0043087 180 0.057
positive regulation of transferase activity GO:0051347 227 0.057
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.057
Human
guanosine containing compound metabolic process GO:1901068 244 0.057
regulation of cellular component biogenesis GO:0044087 281 0.057
limbic system development GO:0021761 3 0.056
segmentation GO:0035282 4 0.056
cellular macromolecule catabolic process GO:0044265 380 0.055
positive regulation of programmed cell death GO:0043068 249 0.055
Human
nucleoside phosphate catabolic process GO:1901292 412 0.055
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
regulation of nucleoside metabolic process GO:0009118 209 0.054
anterior posterior axis specification GO:0009948 2 0.054
chemical homeostasis GO:0048878 306 0.053
ribonucleoside triphosphate catabolic process GO:0009203 391 0.053
positive regulation of nucleotide catabolic process GO:0030813 185 0.053
mitotic cell cycle GO:0000278 326 0.053
intrinsic apoptotic signaling pathway GO:0097193 127 0.052
regulation of cellular response to stress GO:0080135 244 0.052
cellular amine metabolic process GO:0044106 41 0.052
ribonucleotide catabolic process GO:0009261 405 0.051
single organism carbohydrate metabolic process GO:0044723 193 0.051
regulation of small gtpase mediated signal transduction GO:0051056 156 0.051
response to growth factor GO:0070848 205 0.050
regulation of anatomical structure morphogenesis GO:0022603 286 0.050
Human
cellular response to oxygen containing compound GO:1901701 276 0.050
nucleotide catabolic process GO:0009166 408 0.049
neurogenesis GO:0022008 169 0.048
Human Worm
regulation of cytoskeleton organization GO:0051493 177 0.048
positive regulation of gtp catabolic process GO:0033126 166 0.048
regulation of gtp catabolic process GO:0033124 180 0.047
regulation of cell cycle GO:0051726 393 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
neurotransmitter secretion GO:0007269 4 0.045
spermatid differentiation GO:0048515 4 0.045
positive regulation of phosphorylation GO:0042327 394 0.045
immune response GO:0006955 307 0.043
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.043
Human
guanosine containing compound catabolic process GO:1901069 239 0.043
locomotory behavior GO:0007626 1 0.043
regulation of nervous system development GO:0051960 88 0.043
Human
endomembrane system organization GO:0010256 196 0.042
actin cytoskeleton organization GO:0030036 207 0.042
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.042
positive regulation of protein phosphorylation GO:0001934 313 0.042
positive regulation of protein kinase activity GO:0045860 190 0.042
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.042
regulation of neurogenesis GO:0050767 82 0.042
Human
regulation of protein localization GO:0032880 296 0.041
regulation of cell development GO:0060284 161 0.041
Human
nucleoside catabolic process GO:0009164 408 0.041
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.041
response to transforming growth factor beta GO:0071559 94 0.041
positive regulation of kinase activity GO:0033674 204 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
response to oxidative stress GO:0006979 121 0.039
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
nucleoside triphosphate metabolic process GO:0009141 422 0.039
cell adhesion GO:0007155 325 0.039
regulation of kinase activity GO:0043549 314 0.039
t cell differentiation in thymus GO:0033077 4 0.039
cellular response to oxidative stress GO:0034599 85 0.039
cell part morphogenesis GO:0032990 137 0.038
Human
regulation of transferase activity GO:0051338 355 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.037
canonical wnt signaling pathway GO:0060070 116 0.037
positive regulation of nucleotide metabolic process GO:0045981 230 0.037
positive regulation of apoptotic process GO:0043065 246 0.037
Human
regulation of ras gtpase activity GO:0032318 128 0.037
anterior posterior axis specification embryo GO:0008595 2 0.037
carbohydrate metabolic process GO:0005975 207 0.037
neuron projection development GO:0031175 106 0.036
Human
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.036
positive regulation of nucleoside metabolic process GO:0045979 186 0.035
regulation of locomotion GO:0040012 329 0.035
adult locomotory behavior GO:0008344 1 0.035
response to nitrogen compound GO:1901698 184 0.034
growth GO:0040007 202 0.034
positive regulation of ras gtpase activity GO:0032320 117 0.034
nucleus localization GO:0051647 1 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
blastoderm segmentation GO:0007350 2 0.033
compound eye development GO:0048749 1 0.033
signal transduction by phosphorylation GO:0023014 297 0.033
autophagy GO:0006914 88 0.033
metencephalon development GO:0022037 2 0.033
positive regulation of cellular catabolic process GO:0031331 284 0.033
peptidyl tyrosine modification GO:0018212 170 0.033
oocyte differentiation GO:0009994 2 0.033
spermatid development GO:0007286 4 0.032
taxis GO:0042330 157 0.032
cell morphogenesis involved in differentiation GO:0000904 144 0.032
Human
positive regulation of cell projection organization GO:0031346 64 0.031
Human
wnt signaling pathway GO:0016055 156 0.031
oocyte development GO:0048599 1 0.031
organelle localization GO:0051640 84 0.031
negative regulation of cell death GO:0060548 345 0.031
establishment or maintenance of neuroblast polarity GO:0045196 1 0.031
positive regulation of transport GO:0051050 336 0.031
regulation of neuron differentiation GO:0045664 70 0.030
Human
chromatin modification GO:0016568 298 0.030
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.030
neuron development GO:0048666 113 0.030
Human
cellular lipid metabolic process GO:0044255 303 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
Human
regulation of nucleotide metabolic process GO:0006140 269 0.030
intracellular protein transport GO:0006886 270 0.030
lymphocyte activation GO:0046649 133 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.029
nuclear migration GO:0007097 1 0.029
peptidyl serine modification GO:0018209 106 0.029
Worm
regulation of synaptic plasticity GO:0048167 3 0.029
establishment of cell polarity GO:0030010 22 0.029
Human Worm
negative regulation of cellular component organization GO:0051129 235 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
regulation of proteolysis GO:0030162 293 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
axonogenesis GO:0007409 31 0.028
Human
negative regulation of developmental process GO:0051093 247 0.028
Worm
cerebellum development GO:0021549 2 0.028
cell activation GO:0001775 213 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.028
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.028
positive regulation of protein complex assembly GO:0031334 86 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
vesicle mediated transport GO:0016192 371 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.027
head development GO:0060322 108 0.027
establishment of nucleus localization GO:0040023 1 0.027
organophosphate catabolic process GO:0046434 430 0.027
regulation of neuron projection development GO:0010975 57 0.027
Human
actin filament organization GO:0007015 128 0.027
immune system development GO:0002520 195 0.027
histone modification GO:0016570 251 0.027
t cell selection GO:0045058 4 0.027
hippocampus development GO:0021766 1 0.027
neuron projection extension GO:1990138 14 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
cell division GO:0051301 168 0.026
Worm
regulation of rho gtpase activity GO:0032319 66 0.026
brain development GO:0007420 97 0.026
mapk cascade GO:0000165 288 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.026
Human
developmental cell growth GO:0048588 18 0.026
cell growth GO:0016049 160 0.026
gtp catabolic process GO:0006184 237 0.025
negative regulation of apoptotic process GO:0043066 316 0.025
positive regulation of developmental process GO:0051094 314 0.025
Human
regulation of rho protein signal transduction GO:0035023 79 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
maintenance of location GO:0051235 112 0.025
regulation of cellular component movement GO:0051270 334 0.025
regulation of protein kinase activity GO:0045859 289 0.025
axon development GO:0061564 34 0.025
Human
protein catabolic process GO:0030163 325 0.025
protein processing GO:0016485 226 0.024
cellular protein complex assembly GO:0043623 188 0.024
regulation of microtubule cytoskeleton organization GO:0070507 61 0.024
purine containing compound catabolic process GO:0072523 411 0.024
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.024
innate immune response GO:0045087 178 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
tripartite regional subdivision GO:0007351 2 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.024
neuron projection morphogenesis GO:0048812 50 0.024
Human
chromatin organization GO:0006325 351 0.024
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.023
maintenance of cell polarity GO:0030011 2 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
positive regulation of locomotion GO:0040017 186 0.022
golgi localization GO:0051645 4 0.022
regulation of cell projection organization GO:0031344 107 0.022
Human
protein maturation GO:0051604 233 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
chemotaxis GO:0006935 157 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.022
Human
prostate gland development GO:0030850 3 0.022
epithelium development GO:0060429 227 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
regulation of protein maturation GO:1903317 150 0.022
activation of protein kinase activity GO:0032147 90 0.022
protein acylation GO:0043543 138 0.021
response to biotic stimulus GO:0009607 276 0.021
regulation of protein complex assembly GO:0043254 147 0.021
positive regulation of neurogenesis GO:0050769 49 0.021
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.021
negative regulation of cell cycle GO:0045786 193 0.021
hemopoiesis GO:0030097 180 0.021
thymic t cell selection GO:0045061 2 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
regulation of autophagy GO:0010506 52 0.021
response to external biotic stimulus GO:0043207 261 0.020
cellular protein catabolic process GO:0044257 261 0.020
negative regulation of organelle organization GO:0010639 126 0.020
central nervous system development GO:0007417 123 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
cytokine production GO:0001816 247 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
cell substrate adhesion GO:0031589 132 0.020
developmental growth involved in morphogenesis GO:0060560 23 0.020
positive regulation of rho gtpase activity GO:0032321 56 0.020
cardiovascular system development GO:0072358 262 0.020
negative regulation of protein processing GO:0010955 142 0.020
covalent chromatin modification GO:0016569 254 0.019
regulation of microtubule based process GO:0032886 74 0.019
cellular response to hydrogen peroxide GO:0070301 37 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
protein localization to membrane GO:0072657 160 0.019
regulation of jnk cascade GO:0046328 73 0.019
stress activated protein kinase signaling cascade GO:0031098 94 0.019
axon cargo transport GO:0008088 2 0.019
biological adhesion GO:0022610 331 0.019
positive regulation of neuron projection development GO:0010976 34 0.018
Human
negative regulation of proteolysis GO:0045861 132 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
Worm
cellular response to peptide hormone stimulus GO:0071375 56 0.018
long term memory GO:0007616 2 0.018
regulation of immune response GO:0050776 201 0.018
energy homeostasis GO:0097009 3 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
regulation of cell growth GO:0001558 135 0.018
oxidation reduction process GO:0055114 396 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
response to other organism GO:0051707 261 0.018
positive regulation of axon extension GO:0045773 4 0.018
response to organonitrogen compound GO:0010243 156 0.017
regulation of mapk cascade GO:0043408 262 0.017
leukocyte activation GO:0045321 164 0.017
regulation of growth GO:0040008 165 0.017
positive regulation of immune system process GO:0002684 283 0.017
regulation of binding GO:0051098 111 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.017
regulation of cell cycle process GO:0010564 266 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.016
stress activated mapk cascade GO:0051403 93 0.016
secretion GO:0046903 254 0.016
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.016
Human
golgi organization GO:0007030 38 0.016
neural tube formation GO:0001841 3 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
lipid metabolic process GO:0006629 381 0.016
regulation of innate immune response GO:0045088 97 0.016
response to hormone GO:0009725 175 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
regulation of cell motility GO:2000145 299 0.016
embryo development GO:0009790 123 0.016
Worm
negative regulation of protein maturation GO:1903318 142 0.016
organ formation GO:0048645 3 0.016
positive regulation of immune response GO:0050778 159 0.016
jnk cascade GO:0007254 80 0.016
plasma membrane organization GO:0007009 115 0.016
associative learning GO:0008306 1 0.016
signal transduction by p53 class mediator GO:0072331 72 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
somatic stem cell maintenance GO:0035019 4 0.015
vasculature development GO:0001944 181 0.015
protein localization to organelle GO:0033365 280 0.015
regulation of axon guidance GO:1902667 3 0.015
positive regulation of rac gtpase activity GO:0032855 31 0.015
cellular response to peptide GO:1901653 59 0.015
regeneration GO:0031099 4 0.015
response to radiation GO:0009314 151 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
regulation of canonical wnt signaling pathway GO:0060828 88 0.015
positive regulation of protein transport GO:0051222 135 0.015
peptidyl lysine modification GO:0018205 144 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
positive regulation of cell death GO:0010942 263 0.015
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.015
defense response GO:0006952 315 0.015
regulation of cell adhesion GO:0030155 166 0.015
t cell activation GO:0042110 99 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of cellular component size GO:0032535 82 0.014
sensory perception GO:0007600 103 0.014
endosomal transport GO:0016197 129 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
cellular homeostasis GO:0019725 196 0.014
negative regulation of growth GO:0045926 97 0.014
epithelial cell proliferation GO:0050673 128 0.014
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
histone acetylation GO:0016573 93 0.014
activation of immune response GO:0002253 114 0.014
meiotic chromosome segregation GO:0045132 4 0.014
regulation of cytokine production GO:0001817 232 0.014
single organism membrane organization GO:0044802 268 0.014
rab protein signal transduction GO:0032482 4 0.014
cell cycle phase transition GO:0044770 173 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
protein targeting GO:0006605 187 0.014
cell cycle arrest GO:0007050 71 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
small molecule biosynthetic process GO:0044283 157 0.014
response to abiotic stimulus GO:0009628 336 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
neurological system process GO:0050877 163 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
single organism cell adhesion GO:0098602 179 0.013
leukocyte differentiation GO:0002521 98 0.013
cytoplasmic transport GO:0016482 379 0.013
regulation of cellular response to growth factor stimulus GO:0090287 76 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
protein acetylation GO:0006473 116 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.013
somitogenesis GO:0001756 2 0.013
negative regulation of cell growth GO:0030308 83 0.013
establishment or maintenance of cell polarity GO:0007163 31 0.013
Human Worm
secretion by cell GO:0032940 226 0.013
fatty acid metabolic process GO:0006631 115 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
endocytosis GO:0006897 159 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
glycerolipid metabolic process GO:0046486 107 0.012
lipid modification GO:0030258 84 0.012
mitochondrion organization GO:0007005 156 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
visual behavior GO:0007632 2 0.012
system process GO:0003008 349 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
regulation of defense response GO:0031347 154 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
response to wounding GO:0009611 168 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
memory GO:0007613 3 0.012
cerebellar cortex development GO:0021695 1 0.012
cell projection assembly GO:0030031 126 0.012
cytokinesis GO:0000910 96 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
intestinal epithelial cell differentiation GO:0060575 3 0.012
positive regulation of proteolysis GO:0045862 142 0.012
positive regulation of secretion GO:0051047 116 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
regulation of protein catabolic process GO:0042176 155 0.012
positive regulation of wnt signaling pathway GO:0030177 54 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of protein kinase b signaling GO:0051896 61 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
regulation of actin filament based process GO:0032970 141 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
protein ubiquitination GO:0016567 314 0.012
protein modification by small protein removal GO:0070646 92 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
epithelial cell differentiation GO:0030855 141 0.011
cellular component disassembly GO:0022411 92 0.011
positive regulation of cell motility GO:2000147 177 0.011
regulation of protein secretion GO:0050708 86 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
regulation of anatomical structure size GO:0090066 101 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regionalization GO:0003002 29 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
respiratory gaseous exchange GO:0007585 3 0.011
behavior GO:0007610 112 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
anion transport GO:0006820 161 0.011
macromolecular complex disassembly GO:0032984 60 0.011
retinal ganglion cell axon guidance GO:0031290 2 0.011
response to bacterium GO:0009617 144 0.011
dephosphorylation GO:0016311 209 0.011
spindle organization GO:0007051 53 0.011
actomyosin structure organization GO:0031032 59 0.011
regulation of protein processing GO:0070613 150 0.011
regulation of neuron death GO:1901214 56 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
protein deubiquitination GO:0016579 79 0.011
negative regulation of immune system process GO:0002683 136 0.011
aging GO:0007568 66 0.011
regulation of intracellular transport GO:0032386 195 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
wound healing GO:0042060 115 0.011
chromosome segregation GO:0007059 114 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of neuron differentiation GO:0045666 40 0.010
Human
regulation of chromatin organization GO:1902275 56 0.010
negative regulation of protein modification process GO:0031400 200 0.010
negative regulation of gluconeogenesis GO:0045721 2 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
cation transport GO:0006812 331 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
immune response activating signal transduction GO:0002757 90 0.010
regulation of leukocyte activation GO:0002694 115 0.010
ion homeostasis GO:0050801 230 0.010
positive regulation of rab gtpase activity GO:0032851 39 0.010
microtubule polymerization or depolymerization GO:0031109 37 0.010
regulation of protein transport GO:0051223 213 0.010
digestive tract development GO:0048565 75 0.010
organelle assembly GO:0070925 176 0.010

MARK4 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.050
central nervous system disease DOID:331 186 0.050
intestinal disease DOID:5295 14 0.031
gastrointestinal system disease DOID:77 36 0.031
neurodegenerative disease DOID:1289 102 0.026
cancer DOID:162 167 0.022
organ system cancer DOID:0050686 164 0.022
disease of cellular proliferation DOID:14566 174 0.022
brain disease DOID:936 73 0.019
endocrine gland cancer DOID:170 26 0.015
immune system disease DOID:2914 155 0.012
disease of metabolism DOID:0014667 295 0.012
synucleinopathy DOID:0050890 22 0.011
disease of mental health DOID:150 70 0.011
inherited metabolic disorder DOID:655 242 0.011
musculoskeletal system disease DOID:17 223 0.010
parkinson s disease DOID:14330 18 0.010