Homo sapiens

15 known processes

MFN1

mitofusin 1

(Aliases: MGC41806,hfzo2,DKFZp762F247,FLJ20693,hfzo1)

MFN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside catabolic process GO:0046130 398 0.441
positive regulation of protein phosphorylation GO:0001934 313 0.437
post embryonic development GO:0009791 2 0.328
ribonucleoside catabolic process GO:0042454 406 0.319
cellular macromolecular complex assembly GO:0034622 324 0.281
purine ribonucleotide catabolic process GO:0009154 404 0.263
organophosphate catabolic process GO:0046434 430 0.238
guanosine containing compound metabolic process GO:1901068 244 0.225
nucleoside phosphate catabolic process GO:1901292 412 0.218
nucleoside triphosphate metabolic process GO:0009141 422 0.200
ribonucleoside triphosphate metabolic process GO:0009199 412 0.189
purine nucleoside catabolic process GO:0006152 398 0.179
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.178
purine nucleoside triphosphate metabolic process GO:0009144 412 0.175
oogenesis GO:0048477 2 0.166
ribonucleotide catabolic process GO:0009261 405 0.165
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.154
cytoplasmic transport GO:0016482 379 0.148
Human
glycosyl compound catabolic process GO:1901658 413 0.147
purine ribonucleoside metabolic process GO:0046128 437 0.145
ribonucleoside triphosphate catabolic process GO:0009203 391 0.139
cell development GO:0048468 328 0.131
nucleoside catabolic process GO:0009164 408 0.106
regulation of cellular amine metabolic process GO:0033238 11 0.106
protein polymerization GO:0051258 71 0.102
regulation of anatomical structure morphogenesis GO:0022603 286 0.100
purine nucleoside triphosphate catabolic process GO:0009146 392 0.098
regulation of nucleotide metabolic process GO:0006140 269 0.096
female gamete generation GO:0007292 2 0.095
positive regulation of phosphorylation GO:0042327 394 0.093
regulation of cell motility GO:2000145 299 0.088
peptidyl serine phosphorylation GO:0018105 101 0.086
rna processing GO:0006396 255 0.084
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.084
locomotory behavior GO:0007626 1 0.083
actin cytoskeleton organization GO:0030036 207 0.081
intracellular protein transport GO:0006886 270 0.081
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.079
cytokine production GO:0001816 247 0.078
gtp metabolic process GO:0046039 239 0.075
neuromuscular junction development GO:0007528 3 0.072
purine nucleotide catabolic process GO:0006195 405 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
response to external biotic stimulus GO:0043207 261 0.064
cytokine mediated signaling pathway GO:0019221 109 0.064
positive regulation of cellular amine metabolic process GO:0033240 7 0.064
positive regulation of transport GO:0051050 336 0.061
positive regulation of cell migration GO:0030335 172 0.061
cellular component morphogenesis GO:0032989 314 0.061
gtp catabolic process GO:0006184 237 0.060
negative regulation of phosphate metabolic process GO:0045936 267 0.060
regulation of locomotion GO:0040012 329 0.058
amine metabolic process GO:0009308 44 0.058
nuclear transport GO:0051169 179 0.057
regulation of cytokine production GO:0001817 232 0.056
cell projection organization GO:0030030 252 0.056
regulation of transferase activity GO:0051338 355 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.053
guanosine containing compound catabolic process GO:1901069 239 0.052
nucleotide catabolic process GO:0009166 408 0.052
regulation of cellular component movement GO:0051270 334 0.050
dna repair GO:0006281 198 0.049
cellular lipid metabolic process GO:0044255 303 0.049
carbohydrate metabolic process GO:0005975 207 0.048
actin filament based process GO:0030029 224 0.046
negative regulation of protein metabolic process GO:0051248 391 0.046
cell morphogenesis GO:0000902 296 0.045
regulation of mitotic cell cycle GO:0007346 189 0.044
positive regulation of cytokine production GO:0001819 167 0.044
cellular response to cytokine stimulus GO:0071345 181 0.043
peptidyl serine modification GO:0018209 106 0.043
response to abiotic stimulus GO:0009628 336 0.043
regulation of dna metabolic process GO:0051052 153 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
protein ubiquitination GO:0016567 314 0.041
regulation of protein serine threonine kinase activity GO:0071900 179 0.040
regulation of cell cycle GO:0051726 393 0.040
vesicle mediated transport GO:0016192 371 0.040
protein modification by small protein conjugation GO:0032446 342 0.040
regulation of cellular component size GO:0032535 82 0.039
negative regulation of phosphorus metabolic process GO:0010563 267 0.039
cellular amine metabolic process GO:0044106 41 0.039
chromatin organization GO:0006325 351 0.039
positive regulation of protein kinase activity GO:0045860 190 0.038
ras protein signal transduction GO:0007265 73 0.038
Human
associative learning GO:0008306 1 0.038
posttranscriptional regulation of gene expression GO:0010608 213 0.037
purine containing compound catabolic process GO:0072523 411 0.036
single organism carbohydrate metabolic process GO:0044723 193 0.036
negative regulation of programmed cell death GO:0043069 321 0.036
response to nitrogen compound GO:1901698 184 0.035
response to other organism GO:0051707 261 0.035
protein localization to organelle GO:0033365 280 0.035
Human
purine nucleoside monophosphate metabolic process GO:0009126 186 0.035
cellular response to nitrogen compound GO:1901699 144 0.035
regulation of nucleotide catabolic process GO:0030811 205 0.035
regulation of cellular component biogenesis GO:0044087 281 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
regulation of protein complex assembly GO:0043254 147 0.034
positive regulation of cell motility GO:2000147 177 0.034
lipid metabolic process GO:0006629 381 0.034
determination of adult lifespan GO:0008340 2 0.034
macromolecule glycosylation GO:0043413 63 0.034
neurological system process GO:0050877 163 0.034
positive regulation of cellular component organization GO:0051130 376 0.033
atp catabolic process GO:0006200 157 0.033
regulation of cell migration GO:0030334 289 0.033
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.032
regulation of protein kinase activity GO:0045859 289 0.032
viral process GO:0016032 146 0.032
response to oxygen containing compound GO:1901700 369 0.032
spermatid differentiation GO:0048515 4 0.031
positive regulation of cellular component movement GO:0051272 181 0.031
cell adhesion GO:0007155 325 0.031
neuron development GO:0048666 113 0.031
response to cytokine GO:0034097 232 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
negative regulation of catalytic activity GO:0043086 335 0.031
regulation of anatomical structure size GO:0090066 101 0.031
ribonucleoside monophosphate metabolic process GO:0009161 187 0.031
cellular protein complex assembly GO:0043623 188 0.030
regulation of protein transport GO:0051223 213 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
spermatid development GO:0007286 4 0.030
regulation of cellular response to stress GO:0080135 244 0.030
positive regulation of catabolic process GO:0009896 310 0.030
regulation of cell development GO:0060284 161 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
rna interference GO:0016246 4 0.029
mitochondrion organization GO:0007005 156 0.029
growth GO:0040007 202 0.029
Worm
mitotic cell cycle process GO:1903047 286 0.029
nucleoside monophosphate catabolic process GO:0009125 159 0.029
regulation of response to external stimulus GO:0032101 222 0.028
regulation of mitotic cell cycle phase transition GO:1901990 118 0.028
cell part morphogenesis GO:0032990 137 0.028
covalent chromatin modification GO:0016569 254 0.028
positive regulation of locomotion GO:0040017 186 0.028
positive regulation of transferase activity GO:0051347 227 0.028
taxis GO:0042330 157 0.028
regulation of vesicle mediated transport GO:0060627 130 0.027
protein catabolic process GO:0030163 325 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
cell aging GO:0007569 52 0.027
positive regulation of mapk cascade GO:0043410 190 0.027
positive regulation of hydrolase activity GO:0051345 331 0.027
nucleoside monophosphate metabolic process GO:0009123 191 0.026
atp metabolic process GO:0046034 176 0.026
neurogenesis GO:0022008 169 0.026
cell cycle phase transition GO:0044770 173 0.026
nucleus localization GO:0051647 1 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
microtubule based process GO:0007017 210 0.026
neuron differentiation GO:0030182 138 0.026
positive regulation of developmental process GO:0051094 314 0.025
Worm
nervous system development GO:0007399 293 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
endosomal transport GO:0016197 129 0.025
response to biotic stimulus GO:0009607 276 0.025
embryo development GO:0009790 123 0.025
Worm
mrna metabolic process GO:0016071 175 0.025
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
membrane organization GO:0061024 292 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
chromatin modification GO:0016568 298 0.024
negative regulation of rho gtpase activity GO:0034259 4 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
positive regulation of organelle organization GO:0010638 195 0.024
positive regulation of dendrite morphogenesis GO:0050775 3 0.023
interspecies interaction between organisms GO:0044419 156 0.023
transmembrane transport GO:0055085 399 0.023
viral life cycle GO:0019058 132 0.023
glycerolipid metabolic process GO:0046486 107 0.023
endomembrane system organization GO:0010256 196 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
multi organism cellular process GO:0044764 156 0.023
mitotic cell cycle GO:0000278 326 0.023
dna replication GO:0006260 116 0.023
positive regulation of immune system process GO:0002684 283 0.022
neuron projection development GO:0031175 106 0.022
rna 3 end processing GO:0031123 35 0.022
regulation of immune response GO:0050776 201 0.022
multicellular organismal aging GO:0010259 3 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
oxidation reduction process GO:0055114 396 0.022
cell type specific apoptotic process GO:0097285 125 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
organelle fission GO:0048285 149 0.022
establishment of organelle localization GO:0051656 59 0.021
regulation of cell differentiation GO:0045595 393 0.021
negative regulation of growth GO:0045926 97 0.021
regulation of ras protein signal transduction GO:0046578 155 0.021
Human
leukocyte activation GO:0045321 164 0.021
oocyte development GO:0048599 1 0.021
negative regulation of cell cycle GO:0045786 193 0.020
regulation of innate immune response GO:0045088 97 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
negative regulation of cell death GO:0060548 345 0.020
cell growth GO:0016049 160 0.020
cellular ketone metabolic process GO:0042180 80 0.020
regulation of kinase activity GO:0043549 314 0.019
meiosis i GO:0007127 4 0.019
innate immune response GO:0045087 178 0.019
protein homooligomerization GO:0051260 100 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
immune response GO:0006955 307 0.019
negative regulation of organelle organization GO:0010639 126 0.019
single organism membrane organization GO:0044802 268 0.019
histone modification GO:0016570 251 0.018
alcohol metabolic process GO:0006066 114 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
Human
mitotic nuclear division GO:0007067 119 0.018
regulation of growth GO:0040008 165 0.018
Worm
negative regulation of cell proliferation GO:0008285 228 0.018
neural tube formation GO:0001841 3 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
developmental growth GO:0048589 48 0.018
Worm
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018
protein localization to mitochondrion GO:0070585 25 0.018
Human
regulation of gene expression epigenetic GO:0040029 73 0.018
regulation of cell adhesion GO:0030155 166 0.018
cellular carbohydrate metabolic process GO:0044262 84 0.018
ribonucleoprotein complex localization GO:0071166 4 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
positive regulation of protein transport GO:0051222 135 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
response to inorganic substance GO:0010035 127 0.017
receptor mediated endocytosis GO:0006898 84 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
negative regulation of lipid metabolic process GO:0045833 38 0.017
protein oligomerization GO:0051259 173 0.017
regulation of protein localization GO:0032880 296 0.017
response to organonitrogen compound GO:0010243 156 0.017
peroxisome organization GO:0007031 28 0.017
biological adhesion GO:0022610 331 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.017
negative regulation of cell cycle process GO:0010948 121 0.016
glycerophospholipid biosynthetic process GO:0046474 40 0.016
positive regulation of intracellular protein transport GO:0090316 76 0.016
defense response to bacterium GO:0042742 63 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
Human
translation GO:0006412 132 0.016
mitotic cell cycle checkpoint GO:0007093 68 0.016
segmentation GO:0035282 4 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
secretion by cell GO:0032940 226 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
chemotaxis GO:0006935 157 0.016
rhythmic behavior GO:0007622 2 0.016
epithelial cell migration GO:0010631 119 0.015
single organism reproductive process GO:0044702 98 0.015
regulation of defense response GO:0031347 154 0.015
regulation of leukocyte activation GO:0002694 115 0.015
positive regulation of immune response GO:0050778 159 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
positive regulation of growth GO:0045927 58 0.015
Worm
positive regulation of apoptotic process GO:0043065 246 0.015
negative regulation of cell adhesion GO:0007162 64 0.015
cell morphogenesis involved in differentiation GO:0000904 144 0.015
coenzyme metabolic process GO:0006732 65 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
regulation of cell cycle process GO:0010564 266 0.015
mrna processing GO:0006397 133 0.015
hippocampus development GO:0021766 1 0.015
behavior GO:0007610 112 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
actin filament organization GO:0007015 128 0.015
protein import GO:0017038 130 0.015
cellular response to peptide hormone stimulus GO:0071375 56 0.015
cell fate determination GO:0001709 3 0.014
generation of neurons GO:0048699 152 0.014
tissue migration GO:0090130 119 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of intracellular transport GO:0032386 195 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
regulation of lipid metabolic process GO:0019216 96 0.014
positive regulation of cell death GO:0010942 263 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
response to tumor necrosis factor GO:0034612 76 0.014
defense response GO:0006952 315 0.014
cell activation GO:0001775 213 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
protein localization to membrane GO:0072657 160 0.014
regulation of viral process GO:0050792 103 0.014
organelle localization GO:0051640 84 0.014
Human
positive regulation of programmed cell death GO:0043068 249 0.014
viral genome replication GO:0019079 50 0.014
regulation of gtpase activity GO:0043087 180 0.014
lipid biosynthetic process GO:0008610 177 0.014
chromosome segregation GO:0007059 114 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
central nervous system development GO:0007417 123 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
oocyte differentiation GO:0009994 2 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.013
response to growth factor GO:0070848 205 0.013
cellular cation homeostasis GO:0030003 163 0.013
regulation of cell activation GO:0050865 125 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
negative regulation of mitotic cell cycle GO:0045930 102 0.013
protein maturation GO:0051604 233 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
protein targeting GO:0006605 187 0.013
Human
reproductive process GO:0022414 106 0.013
metal ion homeostasis GO:0055065 169 0.013
regulation of neuron projection development GO:0010975 57 0.013
cell cycle checkpoint GO:0000075 117 0.013
response to extracellular stimulus GO:0009991 85 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
Human
rho protein signal transduction GO:0007266 26 0.012
regulation of translation GO:0006417 89 0.012
actin filament polymerization GO:0030041 45 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
response to bacterium GO:0009617 144 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
meiotic chromosome segregation GO:0045132 4 0.012
phospholipid biosynthetic process GO:0008654 44 0.012
myoblast fusion GO:0007520 1 0.012
single organism cellular localization GO:1902580 332 0.012
Human
regulation of mapk cascade GO:0043408 262 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
circulatory system development GO:0072359 262 0.012
cell projection morphogenesis GO:0048858 129 0.012
vasodilation GO:0042311 4 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
negative regulation of developmental process GO:0051093 247 0.012
regulation of actin filament based process GO:0032970 141 0.012
regulation of cell projection organization GO:0031344 107 0.012
regulation of map kinase activity GO:0043405 108 0.012
neuron death GO:0070997 65 0.012
regulation of tumor necrosis factor production GO:0032680 43 0.012
double strand break repair GO:0006302 101 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
cognition GO:0050890 43 0.012
response to glucagon GO:0033762 1 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
response to organic cyclic compound GO:0014070 204 0.012
regulation of binding GO:0051098 111 0.012
memory GO:0007613 3 0.012
glycerolipid biosynthetic process GO:0045017 51 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
response to virus GO:0009615 126 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
reproduction GO:0000003 63 0.011
wound healing GO:0042060 115 0.011
neuron apoptotic process GO:0051402 39 0.011
regulation of dna repair GO:0006282 47 0.011
response to oxidative stress GO:0006979 121 0.011
receptor metabolic process GO:0043112 81 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
Worm
endocytosis GO:0006897 159 0.011
rna transport GO:0050658 39 0.011
epithelial cell proliferation GO:0050673 128 0.011
cilium organization GO:0044782 68 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
regulation of cellular response to insulin stimulus GO:1900076 17 0.011
immune effector process GO:0002252 159 0.011
cellular response to nutrient levels GO:0031669 69 0.011
response to light stimulus GO:0009416 87 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.010
positive regulation of protein complex assembly GO:0031334 86 0.010
regulation of protein binding GO:0043393 66 0.010
regulation of viral genome replication GO:0045069 48 0.010
mapk cascade GO:0000165 288 0.010
glycosylation GO:0070085 71 0.010
positive regulation of kinase activity GO:0033674 204 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
somatic muscle development GO:0007525 1 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
chemical homeostasis GO:0048878 306 0.010
epithelium migration GO:0090132 119 0.010
positive regulation of cytoplasmic transport GO:1903651 82 0.010
myosin filament assembly GO:0031034 2 0.010
anterior posterior axis specification GO:0009948 2 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
multicellular organismal reproductive process GO:0048609 40 0.010

MFN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.028
nervous system disease DOID:863 431 0.028
Human
disease of cellular proliferation DOID:14566 174 0.020
cancer DOID:162 167 0.019
disease of metabolism DOID:0014667 295 0.011