Homo sapiens

42 known processes

MAD2L1BP

MAD2L1 binding protein

(Aliases: KIAA0110,RP1-261G23.6,MGC11282,CMT2)

MAD2L1BP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 209 0.136
regulation of transferase activity GO:0051338 355 0.107
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.097
response to abiotic stimulus GO:0009628 336 0.084
purine ribonucleoside metabolic process GO:0046128 437 0.073
regulation of meiosis GO:0040020 3 0.068
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.065
mitotic cell cycle GO:0000278 326 0.064
regulation of cell cycle process GO:0010564 266 0.062
response to oxidative stress GO:0006979 121 0.062
regulation of chromosome segregation GO:0051983 44 0.062
cellular protein catabolic process GO:0044257 261 0.059
post embryonic development GO:0009791 2 0.058
regulation of nuclear division GO:0051783 65 0.058
cell division GO:0051301 168 0.057
male meiosis GO:0007140 1 0.056
cellular macromolecule catabolic process GO:0044265 380 0.055
positive regulation of cellular catabolic process GO:0031331 284 0.055
regulation of cellular amine metabolic process GO:0033238 11 0.053
cellular amino acid metabolic process GO:0006520 116 0.053
negative regulation of cellular protein metabolic process GO:0032269 353 0.052
protein catabolic process GO:0030163 325 0.051
modification dependent macromolecule catabolic process GO:0043632 212 0.051
regulation of cell cycle GO:0051726 393 0.050
purine nucleoside catabolic process GO:0006152 398 0.050
regulation of cellular response to stress GO:0080135 244 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.048
regulation of cytokine production GO:0001817 232 0.047
negative regulation of programmed cell death GO:0043069 321 0.047
positive regulation of response to external stimulus GO:0032103 88 0.047
dna repair GO:0006281 198 0.046
amine metabolic process GO:0009308 44 0.045
nucleotide catabolic process GO:0009166 408 0.044
ion transmembrane transport GO:0034220 338 0.043
signal transduction by phosphorylation GO:0023014 297 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
ubiquitin dependent protein catabolic process GO:0006511 206 0.041
cellular amine metabolic process GO:0044106 41 0.041
rna processing GO:0006396 255 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
negative regulation of protein modification process GO:0031400 200 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
negative regulation of apoptotic process GO:0043066 316 0.039
cellular response to dna damage stimulus GO:0006974 379 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
negative regulation of cellular component organization GO:0051129 235 0.038
negative regulation of protein processing GO:0010955 142 0.038
negative regulation of protein metabolic process GO:0051248 391 0.037
gtp metabolic process GO:0046039 239 0.037
positive regulation of phosphorylation GO:0042327 394 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
regulation of cell cycle phase transition GO:1901987 126 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
regulation of cell division GO:0051302 116 0.035
regulation of response to external stimulus GO:0032101 222 0.035
positive regulation of transport GO:0051050 336 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
regulation of proteolysis GO:0030162 293 0.034
oxidation reduction process GO:0055114 396 0.034
gtp catabolic process GO:0006184 237 0.033
monocyte activation GO:0042117 3 0.033
negative regulation of cell cycle GO:0045786 193 0.033
blastoderm segmentation GO:0007350 2 0.033
response to inorganic substance GO:0010035 127 0.033
cell morphogenesis GO:0000902 296 0.033
small gtpase mediated signal transduction GO:0007264 78 0.032
cellular ketone metabolic process GO:0042180 80 0.032
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.032
negative regulation of cell death GO:0060548 345 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
regulation of kinase activity GO:0043549 314 0.031
spermatid development GO:0007286 4 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.031
regulation of cellular protein catabolic process GO:1903362 96 0.031
positive regulation of nucleotide catabolic process GO:0030813 185 0.031
cellular response to oxygen containing compound GO:1901701 276 0.030
chromosome segregation GO:0007059 114 0.030
protein maturation GO:0051604 233 0.030
negative regulation of organelle organization GO:0010639 126 0.030
mapk cascade GO:0000165 288 0.030
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
double strand break repair GO:0006302 101 0.029
proteasomal protein catabolic process GO:0010498 176 0.029
positive regulation of catabolic process GO:0009896 310 0.029
cellular lipid metabolic process GO:0044255 303 0.029
asymmetric neuroblast division GO:0055059 1 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
glycosyl compound catabolic process GO:1901658 413 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.028
negative regulation of cell cycle process GO:0010948 121 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.028
syncytium formation by plasma membrane fusion GO:0000768 2 0.028
purine containing compound catabolic process GO:0072523 411 0.028
cellular response to abiotic stimulus GO:0071214 117 0.028
nucleoside catabolic process GO:0009164 408 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
defense response GO:0006952 315 0.027
negative regulation of cellular catabolic process GO:0031330 83 0.027
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.027
guanosine containing compound catabolic process GO:1901069 239 0.027
multicellular organismal aging GO:0010259 3 0.027
cellular response to starvation GO:0009267 58 0.027
neuromuscular junction development GO:0007528 3 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
cell adhesion GO:0007155 325 0.026
spermatid differentiation GO:0048515 4 0.026
negative regulation of chromosome organization GO:2001251 48 0.026
oogenesis GO:0048477 2 0.025
cellular response to external stimulus GO:0071496 111 0.025
negative regulation of developmental process GO:0051093 247 0.025
morphogenesis of embryonic epithelium GO:0016331 4 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
locomotory behavior GO:0007626 1 0.025
cell cycle phase transition GO:0044770 173 0.025
regulation of synaptic plasticity GO:0048167 3 0.024
innate immune response GO:0045087 178 0.024
cellular response to nutrient levels GO:0031669 69 0.024
biological adhesion GO:0022610 331 0.024
response to biotic stimulus GO:0009607 276 0.024
negative regulation of cell cycle phase transition GO:1901988 89 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
wnt signaling pathway GO:0016055 156 0.024
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.024
negative regulation of catabolic process GO:0009895 104 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
regulation of gtpase activity GO:0043087 180 0.023
positive regulation of t cell migration GO:2000406 13 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
female gamete generation GO:0007292 2 0.023
epithelium migration GO:0090132 119 0.023
positive regulation of cell cycle GO:0045787 140 0.023
organophosphate catabolic process GO:0046434 430 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.022
lipid metabolic process GO:0006629 381 0.022
receptor transactivation GO:0035624 4 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
regeneration GO:0031099 4 0.022
organelle fission GO:0048285 149 0.022
regulation of mapk cascade GO:0043408 262 0.022
positive regulation of cell death GO:0010942 263 0.021
tissue migration GO:0090130 119 0.021
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.021
negative regulation of proteolysis GO:0045861 132 0.021
positive regulation of transferase activity GO:0051347 227 0.021
regulation of protein kinase activity GO:0045859 289 0.021
positive regulation of keratinocyte migration GO:0051549 4 0.021
single organism cell adhesion GO:0098602 179 0.021
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.021
positive regulation of cell cycle process GO:0090068 106 0.021
cell projection organization GO:0030030 252 0.021
negative regulation of transferase activity GO:0051348 124 0.021
negative regulation of cellular protein catabolic process GO:1903363 38 0.021
cell development GO:0048468 328 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
immune response GO:0006955 307 0.020
regulation of cell growth GO:0001558 135 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
regulation of protein processing GO:0070613 150 0.020
regulation of meiotic cell cycle GO:0051445 4 0.020
regulation of cell development GO:0060284 161 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
cation transport GO:0006812 331 0.020
response to other organism GO:0051707 261 0.020
determination of adult lifespan GO:0008340 2 0.020
positive regulation of chromosome segregation GO:0051984 9 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
regulation of locomotion GO:0040012 329 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
response to oxygen containing compound GO:1901700 369 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
protein processing GO:0016485 226 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.019
regulation of sister chromatid segregation GO:0033045 27 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
regulation of mitotic cell cycle phase transition GO:1901990 118 0.019
covalent chromatin modification GO:0016569 254 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
response to oxygen levels GO:0070482 100 0.019
regulation of cellular component movement GO:0051270 334 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
protein localization to organelle GO:0033365 280 0.018
cytokine production GO:0001816 247 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
nuclear division GO:0000280 128 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
negative regulation of cytokine production GO:0001818 82 0.018
negative regulation of cell migration GO:0030336 102 0.018
histone modification GO:0016570 251 0.018
segmentation GO:0035282 4 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
regulation of protein catabolic process GO:0042176 155 0.018
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.018
negative regulation of protein catabolic process GO:0042177 59 0.018
positive regulation of kinase activity GO:0033674 204 0.018
negative regulation of protein maturation GO:1903318 142 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
regulation of protein serine threonine kinase activity GO:0071900 179 0.017
spindle checkpoint GO:0031577 26 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
cation transmembrane transport GO:0098655 238 0.017
histone h4 k5 acetylation GO:0043981 15 0.017
meiotic chromosome segregation GO:0045132 4 0.017
regulation of microtubule based process GO:0032886 74 0.017
regulation of protein maturation GO:1903317 150 0.017
fatty acid metabolic process GO:0006631 115 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
single organismal cell cell adhesion GO:0016337 148 0.017
transmembrane transport GO:0055085 399 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
positive regulation of organelle organization GO:0010638 195 0.016
cell cycle checkpoint GO:0000075 117 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.016
atp metabolic process GO:0046034 176 0.016
mesenchyme development GO:0060485 59 0.016
apoptotic signaling pathway GO:0097190 268 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
regulation of chromosome organization GO:0033044 103 0.016
positive regulation of locomotion GO:0040017 186 0.016
regulation of cell migration GO:0030334 289 0.016
nervous system development GO:0007399 293 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
negative regulation of locomotion GO:0040013 118 0.016
epithelial cell proliferation GO:0050673 128 0.015
g protein coupled receptor signaling pathway GO:0007186 207 0.015
response to radiation GO:0009314 151 0.015
neuroblast proliferation GO:0007405 4 0.015
cell growth GO:0016049 160 0.015
spinal cord development GO:0021510 4 0.015
negative regulation of cell division GO:0051782 31 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
protein deubiquitination GO:0016579 79 0.015
response to extracellular stimulus GO:0009991 85 0.015
macroautophagy GO:0016236 39 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of keratinocyte migration GO:0051547 4 0.015
positive regulation of cell migration GO:0030335 172 0.015
hindbrain development GO:0030902 3 0.015
regulation of autophagy GO:0010506 52 0.015
chromosome separation GO:0051304 23 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
epithelial cell differentiation GO:0030855 141 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
ras protein signal transduction GO:0007265 73 0.015
cell substrate adhesion GO:0031589 132 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.014
positive regulation of immune system process GO:0002684 283 0.014
response to cytokine GO:0034097 232 0.014
regulation of secretion by cell GO:1903530 177 0.014
mitotic nuclear division GO:0007067 119 0.014
cytoplasmic transport GO:0016482 379 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
regulation of cell motility GO:2000145 299 0.014
t cell differentiation in thymus GO:0033077 4 0.014
metal ion transport GO:0030001 272 0.014
response to decreased oxygen levels GO:0036293 96 0.014
rho protein signal transduction GO:0007266 26 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.013
interspecies interaction between organisms GO:0044419 156 0.013
response to ionizing radiation GO:0010212 65 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
sister chromatid segregation GO:0000819 54 0.013
positive regulation of cytokine production GO:0001819 167 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of homeostatic process GO:0032844 121 0.013
response to nutrient levels GO:0031667 81 0.013
response to metal ion GO:0010038 84 0.013
cellular response to lipid GO:0071396 127 0.013
regulation of dna metabolic process GO:0051052 153 0.013
dephosphorylation GO:0016311 209 0.013
regulation of leukocyte migration GO:0002685 63 0.013
regulation of binding GO:0051098 111 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
negative regulation of protein ubiquitination GO:0031397 35 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
anterior posterior axis specification GO:0009948 2 0.013
protein ubiquitination GO:0016567 314 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.013
regulation of behavior GO:0050795 82 0.013
positive regulation of leukocyte migration GO:0002687 46 0.013
regulation of cell projection organization GO:0031344 107 0.013
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.012
response to wounding GO:0009611 168 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.012
regulation of growth GO:0040008 165 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
cellular component morphogenesis GO:0032989 314 0.012
cellular response to radiation GO:0071478 65 0.012
mitotic spindle checkpoint GO:0071174 18 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
epithelium development GO:0060429 227 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
peripheral nervous system development GO:0007422 2 0.012
chromatin modification GO:0016568 298 0.012
positive regulation of protein catabolic process GO:0045732 75 0.012
secretion GO:0046903 254 0.012
cellular cation homeostasis GO:0030003 163 0.012
response to external biotic stimulus GO:0043207 261 0.012
positive regulation of meiotic cell cycle GO:0051446 2 0.012
blastocyst development GO:0001824 3 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.012
regulation of multi organism process GO:0043900 157 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
actin filament based process GO:0030029 224 0.012
response to organic cyclic compound GO:0014070 204 0.012
memory GO:0007613 3 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
spindle assembly checkpoint GO:0071173 17 0.012
regulation of axon guidance GO:1902667 3 0.012
sequestering of metal ion GO:0051238 24 0.012
hemopoiesis GO:0030097 180 0.011
single organism cellular localization GO:1902580 332 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
regulation of transmembrane transport GO:0034762 139 0.011
oocyte differentiation GO:0009994 2 0.011
regulation of protein localization GO:0032880 296 0.011
cellular response to biotic stimulus GO:0071216 71 0.011
motor neuron axon guidance GO:0008045 2 0.011
somatic stem cell maintenance GO:0035019 4 0.011
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.011
tissue morphogenesis GO:0048729 96 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
protein acylation GO:0043543 138 0.011
response to fungus GO:0009620 4 0.011
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.011
chromatin organization GO:0006325 351 0.011
positive regulation of cell motility GO:2000147 177 0.011
response to hormone GO:0009725 175 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
cellular response to oxidative stress GO:0034599 85 0.011
metencephalon development GO:0022037 2 0.011
negative regulation of chromosome segregation GO:0051985 18 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
circulatory system development GO:0072359 262 0.011
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
secretion by cell GO:0032940 226 0.011
protein dephosphorylation GO:0006470 81 0.011
mitochondrion organization GO:0007005 156 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
negative regulation of kinase activity GO:0033673 106 0.011
regulation of mitotic sister chromatid segregation GO:0033047 27 0.011
regulation of ion transmembrane transporter activity GO:0032412 72 0.011
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 2 0.011
response to virus GO:0009615 126 0.011
oocyte maturation GO:0001556 1 0.011
positive regulation of proteolysis GO:0045862 142 0.011
chemotaxis GO:0006935 157 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
negative regulation of cell motility GO:2000146 104 0.010
regulation of ligase activity GO:0051340 29 0.010
regulation of ion transport GO:0043269 189 0.010
adult locomotory behavior GO:0008344 1 0.010
notch receptor processing GO:0007220 2 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
protein localization to chromosome GO:0034502 30 0.010
positive regulation of nuclear division GO:0051785 27 0.010
regulation of cell differentiation GO:0045595 393 0.010
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.010
metaphase anaphase transition of cell cycle GO:0044784 21 0.010
mrna metabolic process GO:0016071 175 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
regulation of neuron projection development GO:0010975 57 0.010
cell projection morphogenesis GO:0048858 129 0.010
endocytosis GO:0006897 159 0.010
regulation of transporter activity GO:0032409 82 0.010
positive regulation of cell growth GO:0030307 48 0.010
small molecule biosynthetic process GO:0044283 157 0.010
histone h3 acetylation GO:0043966 45 0.010
negative regulation of cell growth GO:0030308 83 0.010
positive regulation of protein transport GO:0051222 135 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
stem cell differentiation GO:0048863 93 0.010

MAD2L1BP disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.127
cancer DOID:162 167 0.065
organ system cancer DOID:0050686 164 0.063
disease of metabolism DOID:0014667 295 0.036
sensory system disease DOID:0050155 203 0.024
eye and adnexa disease DOID:1492 150 0.024
nervous system disease DOID:863 431 0.024
reproductive organ cancer DOID:193 23 0.017
eye disease DOID:5614 149 0.016
inherited metabolic disorder DOID:655 242 0.014
cardiovascular system disease DOID:1287 106 0.013
gastrointestinal system cancer DOID:3119 52 0.011
acquired metabolic disease DOID:0060158 58 0.010
disease of mental health DOID:150 70 0.010