Homo sapiens

17 known processes

LIG3

ligase III, DNA, ATP-dependent

(Aliases: LIG2)

LIG3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna damage response detection of dna damage GO:0042769 3 0.267
cellular response to dna damage stimulus GO:0006974 379 0.141
Mouse Rat
limbic system development GO:0021761 3 0.122
cellular amino acid metabolic process GO:0006520 116 0.118
base excision repair GO:0006284 21 0.117
Rat
response to oxidative stress GO:0006979 121 0.078
dna repair GO:0006281 198 0.072
Mouse Rat
amine metabolic process GO:0009308 44 0.054
carbohydrate derivative biosynthetic process GO:1901137 207 0.048
nucleoside catabolic process GO:0009164 408 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.044
cellular ketone metabolic process GO:0042180 80 0.044
nucleocytoplasmic transport GO:0006913 176 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
anterior posterior axis specification GO:0009948 2 0.041
response to hypoxia GO:0001666 96 0.038
response to abiotic stimulus GO:0009628 336 0.038
determination of adult lifespan GO:0008340 2 0.037
organophosphate catabolic process GO:0046434 430 0.036
post embryonic development GO:0009791 2 0.035
response to decreased oxygen levels GO:0036293 96 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.033
single organism cellular localization GO:1902580 332 0.032
segmentation GO:0035282 4 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.030
double strand break repair GO:0006302 101 0.028
Mouse
cellular amine metabolic process GO:0044106 41 0.028
cytoplasmic transport GO:0016482 379 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
negative regulation of cell death GO:0060548 345 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
negative regulation of apoptotic process GO:0043066 316 0.027
response to oxygen containing compound GO:1901700 369 0.027
nervous system development GO:0007399 293 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.026
dephosphorylation GO:0016311 209 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
protein localization to organelle GO:0033365 280 0.026
positive regulation of dna metabolic process GO:0051054 73 0.026
negative regulation of programmed cell death GO:0043069 321 0.025
carbohydrate metabolic process GO:0005975 207 0.025
positive regulation of cellular component organization GO:0051130 376 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
glycoprotein metabolic process GO:0009100 110 0.024
protein import into nucleus GO:0006606 104 0.024
ribonucleotide catabolic process GO:0009261 405 0.023
cell projection organization GO:0030030 252 0.023
cell morphogenesis GO:0000902 296 0.023
regulation of intracellular transport GO:0032386 195 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
positive regulation of catabolic process GO:0009896 310 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
negative regulation of protein metabolic process GO:0051248 391 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of transferase activity GO:0051338 355 0.022
blastoderm segmentation GO:0007350 2 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
intracellular protein transport GO:0006886 270 0.022
endomembrane system organization GO:0010256 196 0.022
pallium development GO:0021543 10 0.022
detection of stimulus GO:0051606 85 0.022
oocyte development GO:0048599 1 0.022
ras protein signal transduction GO:0007265 73 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
anterior posterior axis specification embryo GO:0008595 2 0.021
glycosylation GO:0070085 71 0.021
mitotic cell cycle GO:0000278 326 0.021
head development GO:0060322 108 0.021
protein localization to nucleus GO:0034504 136 0.021
regulation of kinase activity GO:0043549 314 0.021
regulation of growth rate GO:0040009 1 0.020
immune response GO:0006955 307 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
nucleotide catabolic process GO:0009166 408 0.020
cellular component morphogenesis GO:0032989 314 0.020
protein poly adp ribosylation GO:0070212 3 0.020
protein import GO:0017038 130 0.020
cellular lipid metabolic process GO:0044255 303 0.020
apoptotic signaling pathway GO:0097190 268 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
regulation of cellular component movement GO:0051270 334 0.019
cation transport GO:0006812 331 0.019
defense response GO:0006952 315 0.019
vesicle mediated transport GO:0016192 371 0.019
membrane organization GO:0061024 292 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
oocyte differentiation GO:0009994 2 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
adult locomotory behavior GO:0008344 1 0.018
system process GO:0003008 349 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
dna catabolic process GO:0006308 49 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
nuclear import GO:0051170 106 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
immune effector process GO:0002252 159 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
regulation of protein kinase activity GO:0045859 289 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
ion transmembrane transport GO:0034220 338 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
purine containing compound catabolic process GO:0072523 411 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
single organism membrane organization GO:0044802 268 0.017
single organism nuclear import GO:1902593 104 0.017
mitotic cell cycle process GO:1903047 286 0.017
positive regulation of immune system process GO:0002684 283 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
nucleoside monophosphate catabolic process GO:0009125 159 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
lipid metabolic process GO:0006629 381 0.017
protein autoprocessing GO:0016540 4 0.017
response to drug GO:0042493 81 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
histone modification GO:0016570 251 0.016
locomotory behavior GO:0007626 1 0.016
oogenesis GO:0048477 2 0.016
lipid biosynthetic process GO:0008610 177 0.016
protein maturation GO:0051604 233 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
actin filament based process GO:0030029 224 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.016
female gamete generation GO:0007292 2 0.016
hindbrain development GO:0030902 3 0.016
metal ion transport GO:0030001 272 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
innate immune response GO:0045087 178 0.015
regulation of proteolysis GO:0030162 293 0.015
regulation of cellular response to stress GO:0080135 244 0.015
atp metabolic process GO:0046034 176 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
organic acid biosynthetic process GO:0016053 97 0.015
ion homeostasis GO:0050801 230 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
negative regulation of cell cycle GO:0045786 193 0.015
cell division GO:0051301 168 0.015
cell adhesion GO:0007155 325 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
macromolecule methylation GO:0043414 97 0.015
amino acid activation GO:0043038 12 0.014
maintenance of location GO:0051235 112 0.014
epithelium development GO:0060429 227 0.014
nuclear migration GO:0007097 1 0.014
immune system development GO:0002520 195 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
translation GO:0006412 132 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
regulation of cytokine production GO:0001817 232 0.014
protein processing GO:0016485 226 0.014
regulation of protein transport GO:0051223 213 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
protein catabolic process GO:0030163 325 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
biological adhesion GO:0022610 331 0.014
positive regulation of developmental process GO:0051094 314 0.014
viral process GO:0016032 146 0.014
regulation of dna metabolic process GO:0051052 153 0.014
Mouse
tripartite regional subdivision GO:0007351 2 0.014
regeneration GO:0031099 4 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
protein targeting to nucleus GO:0044744 104 0.013
endocytosis GO:0006897 159 0.013
positive regulation of cell death GO:0010942 263 0.013
dna replication GO:0006260 116 0.013
methylation GO:0032259 106 0.013
positive regulation of organelle organization GO:0010638 195 0.013
nucleus localization GO:0051647 1 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
chemical homeostasis GO:0048878 306 0.013
cellular protein complex assembly GO:0043623 188 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
rho protein signal transduction GO:0007266 26 0.013
regulation of immune response GO:0050776 201 0.013
regulation of peptidase activity GO:0052547 180 0.013
forebrain development GO:0030900 26 0.013
regulation of actin filament based process GO:0032970 141 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
regulation of cell adhesion GO:0030155 166 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
transmembrane transport GO:0055085 399 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
regulation of protein catabolic process GO:0042176 155 0.013
cellular response to oxygen containing compound GO:1901701 276 0.012
alpha amino acid metabolic process GO:1901605 72 0.012
compound eye development GO:0048749 1 0.012
regulation of protein targeting GO:1903533 91 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
cell part morphogenesis GO:0032990 137 0.012
brain development GO:0007420 97 0.012
regulation of cell differentiation GO:0045595 393 0.012
central nervous system development GO:0007417 123 0.012
regulation of protein localization GO:0032880 296 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
meiotic chromosome segregation GO:0045132 4 0.012
actin filament based movement GO:0030048 17 0.012
response to reactive oxygen species GO:0000302 61 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
nuclear transport GO:0051169 179 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
lymphocyte activation GO:0046649 133 0.012
multicellular organismal aging GO:0010259 3 0.012
gtp metabolic process GO:0046039 239 0.012
response to other organism GO:0051707 261 0.012
neuromuscular junction development GO:0007528 3 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of gtpase activity GO:0043087 180 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
meiosis i GO:0007127 4 0.012
positive regulation of immune response GO:0050778 159 0.012
cell projection assembly GO:0030031 126 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
blastocyst development GO:0001824 3 0.012
nitrogen compound transport GO:0071705 191 0.012
nucleotide biosynthetic process GO:0009165 109 0.011
cellular homeostasis GO:0019725 196 0.011
spermatid differentiation GO:0048515 4 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
regulation of cell migration GO:0030334 289 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
cation transmembrane transport GO:0098655 238 0.011
viral life cycle GO:0019058 132 0.011
telencephalon development GO:0021537 17 0.011
cellular modified amino acid metabolic process GO:0006575 64 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
regulation of cell motility GO:2000145 299 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
organelle localization GO:0051640 84 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
cytokine production GO:0001816 247 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
organelle assembly GO:0070925 176 0.011
ventricular septum morphogenesis GO:0060412 3 0.011
developmental programmed cell death GO:0010623 3 0.011
growth GO:0040007 202 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
neurological system process GO:0050877 163 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
covalent chromatin modification GO:0016569 254 0.011
protein targeting GO:0006605 187 0.011
cell growth GO:0016049 160 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
protein glycosylation GO:0006486 62 0.011
gtp catabolic process GO:0006184 237 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
response to organonitrogen compound GO:0010243 156 0.010
protein modification by small protein removal GO:0070646 92 0.010
multi organism cellular process GO:0044764 156 0.010
regulation of protein stability GO:0031647 87 0.010
leukocyte activation GO:0045321 164 0.010
single organism reproductive process GO:0044702 98 0.010
response to acid chemical GO:0001101 66 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
actin cytoskeleton organization GO:0030036 207 0.010
regulation of cell growth GO:0001558 135 0.010
positive regulation of transferase activity GO:0051347 227 0.010
positive regulation of gtpase activity GO:0043547 166 0.010

LIG3 disease predictions

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 41 0.504
central nervous system disease DOID:331 186 0.504
brain disease DOID:936 73 0.504
electroclinical syndrome DOID:0050701 32 0.504
neonatal period electroclinical syndrome DOID:0050702 19 0.504
nervous system disease DOID:863 431 0.504
idiopathic generalized epilepsy DOID:1827 21 0.058
ohtahara syndrome DOID:0050709 17 0.057
disease of metabolism DOID:0014667 295 0.039
inherited metabolic disorder DOID:655 242 0.037
disease of cellular proliferation DOID:14566 174 0.033
primary ciliary dyskinesia DOID:9562 27 0.018
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
amino acid metabolic disorder DOID:9252 50 0.016
infantile epileptic encephalopathy DOID:2481 12 0.013
neurodegenerative disease DOID:1289 102 0.012
carbohydrate metabolic disorder DOID:2978 55 0.011
gastrointestinal system cancer DOID:3119 52 0.011
neuropathy DOID:870 52 0.011