Homo sapiens

0 known processes

IREB2

iron-responsive element binding protein 2

(Aliases: IRP2AD,ACO3,FLJ23381,IRP2)

IREB2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.116
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.107
ribonucleoside catabolic process GO:0042454 406 0.103
purine nucleoside triphosphate metabolic process GO:0009144 412 0.102
neuromuscular junction development GO:0007528 3 0.101
protein modification by small protein conjugation GO:0032446 342 0.098
purine ribonucleotide catabolic process GO:0009154 404 0.097
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.096
nucleotide catabolic process GO:0009166 408 0.096
ribonucleotide catabolic process GO:0009261 405 0.091
ribonucleoside triphosphate catabolic process GO:0009203 391 0.086
glycosyl compound catabolic process GO:1901658 413 0.083
regulation of cell differentiation GO:0045595 393 0.082
purine nucleoside catabolic process GO:0006152 398 0.071
ribonucleoside triphosphate metabolic process GO:0009199 412 0.067
nucleoside triphosphate metabolic process GO:0009141 422 0.065
regulation of tor signaling GO:0032006 30 0.061
purine containing compound catabolic process GO:0072523 411 0.061
nucleoside triphosphate catabolic process GO:0009143 394 0.061
ribonucleoside monophosphate metabolic process GO:0009161 187 0.058
purine nucleoside triphosphate catabolic process GO:0009146 392 0.057
regulation of cellular amine metabolic process GO:0033238 11 0.057
cellular macromolecule catabolic process GO:0044265 380 0.056
locomotory behavior GO:0007626 1 0.056
regulation of cellular ketone metabolic process GO:0010565 50 0.056
sensory perception of smell GO:0007608 2 0.054
nucleoside catabolic process GO:0009164 408 0.050
negative regulation of multicellular organismal process GO:0051241 317 0.048
viral process GO:0016032 146 0.047
cellular amino acid metabolic process GO:0006520 116 0.047
cellular lipid metabolic process GO:0044255 303 0.043
protein catabolic process GO:0030163 325 0.043
protein ubiquitination GO:0016567 314 0.043
post embryonic development GO:0009791 2 0.042
nucleoside monophosphate catabolic process GO:0009125 159 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.041
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.041
lipid metabolic process GO:0006629 381 0.041
negative regulation of developmental process GO:0051093 247 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
cellular ketone metabolic process GO:0042180 80 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.039
organophosphate catabolic process GO:0046434 430 0.039
purine nucleoside monophosphate metabolic process GO:0009126 186 0.039
determination of adult lifespan GO:0008340 2 0.038
rna processing GO:0006396 255 0.038
cellular amine metabolic process GO:0044106 41 0.038
atp catabolic process GO:0006200 157 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
chemical homeostasis GO:0048878 306 0.036
amine metabolic process GO:0009308 44 0.036
purine nucleoside monophosphate catabolic process GO:0009128 158 0.035
cellular protein catabolic process GO:0044257 261 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.033
atp metabolic process GO:0046034 176 0.032
glycerolipid metabolic process GO:0046486 107 0.032
negative regulation of cell death GO:0060548 345 0.032
regulation of kinase activity GO:0043549 314 0.032
system process GO:0003008 349 0.032
positive regulation of synaptic transmission GO:0050806 4 0.032
gtp catabolic process GO:0006184 237 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
mrna metabolic process GO:0016071 175 0.030
nucleoside monophosphate metabolic process GO:0009123 191 0.029
positive regulation of cell proliferation GO:0008284 301 0.028
neurotransmitter secretion GO:0007269 4 0.028
chromatin organization GO:0006325 351 0.028
protein modification by small protein removal GO:0070646 92 0.027
mrna processing GO:0006397 133 0.027
negative regulation of catalytic activity GO:0043086 335 0.026
immune response GO:0006955 307 0.026
regulation of mapk cascade GO:0043408 262 0.026
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
single organism cellular localization GO:1902580 332 0.026
negative regulation of cell differentiation GO:0045596 171 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
cellular component morphogenesis GO:0032989 314 0.026
hemopoiesis GO:0030097 180 0.026
rna splicing GO:0008380 131 0.026
regulation of proteolysis GO:0030162 293 0.026
nervous system development GO:0007399 293 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
segmentation GO:0035282 4 0.025
growth GO:0040007 202 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.025
ion transmembrane transport GO:0034220 338 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
regulation of transferase activity GO:0051338 355 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
cation transport GO:0006812 331 0.024
regulation of protein kinase activity GO:0045859 289 0.023
multicellular organismal aging GO:0010259 3 0.023
cellular response to endogenous stimulus GO:0071495 336 0.023
histone modification GO:0016570 251 0.023
inorganic cation transmembrane transport GO:0098662 194 0.023
cofactor metabolic process GO:0051186 87 0.023
metal ion transport GO:0030001 272 0.023
coenzyme metabolic process GO:0006732 65 0.022
inorganic ion transmembrane transport GO:0098660 231 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
interspecies interaction between organisms GO:0044419 156 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
regulation of cellular response to stress GO:0080135 244 0.022
multi organism cellular process GO:0044764 156 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
positive regulation of immune system process GO:0002684 283 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
response to nitrogen compound GO:1901698 184 0.021
response to cytokine GO:0034097 232 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
mitotic cell cycle GO:0000278 326 0.021
protein maturation GO:0051604 233 0.021
secretion by cell GO:0032940 226 0.021
ion homeostasis GO:0050801 230 0.020
stress activated protein kinase signaling cascade GO:0031098 94 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
endomembrane system organization GO:0010256 196 0.020
response to other organism GO:0051707 261 0.020
transmembrane transport GO:0055085 399 0.020
response to oxygen containing compound GO:1901700 369 0.020
Rat
cell morphogenesis GO:0000902 296 0.020
ras protein signal transduction GO:0007265 73 0.020
cation transmembrane transport GO:0098655 238 0.020
cell cycle phase transition GO:0044770 173 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
epithelial cell migration GO:0010631 119 0.019
protein processing GO:0016485 226 0.019
acylglycerol metabolic process GO:0006639 27 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
regulation of peptidase activity GO:0052547 180 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
translation GO:0006412 132 0.019
endodermal cell fate commitment GO:0001711 4 0.019
regulation of anatomical structure size GO:0090066 101 0.019
carbohydrate metabolic process GO:0005975 207 0.018
positive regulation of catabolic process GO:0009896 310 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
positive regulation of axon extension GO:0045773 4 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
regulation of cell motility GO:2000145 299 0.018
regulation of stress activated mapk cascade GO:0032872 84 0.018
sensory perception of chemical stimulus GO:0007606 38 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
female gamete generation GO:0007292 2 0.018
regulation of cell migration GO:0030334 289 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.017
spermatid development GO:0007286 4 0.017
rna interference GO:0016246 4 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
regulation of growth GO:0040008 165 0.017
metal ion homeostasis GO:0055065 169 0.017
single organismal cell cell adhesion GO:0016337 148 0.017
immune system development GO:0002520 195 0.017
negative regulation of synaptic transmission GO:0050805 2 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
receptor metabolic process GO:0043112 81 0.017
ameboidal type cell migration GO:0001667 135 0.017
cytoplasmic transport GO:0016482 379 0.017
mitotic cell cycle process GO:1903047 286 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
regulation of epithelial cell migration GO:0010632 93 0.017
lipid biosynthetic process GO:0008610 177 0.017
regulation of cell cycle GO:0051726 393 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.016
cytokine production GO:0001816 247 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
cell cell signaling GO:0007267 155 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of viral process GO:0050792 103 0.016
tissue migration GO:0090130 119 0.016
protein polyubiquitination GO:0000209 110 0.016
regulation of cellular component movement GO:0051270 334 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
spermatid differentiation GO:0048515 4 0.016
viral life cycle GO:0019058 132 0.016
covalent chromatin modification GO:0016569 254 0.016
cellular homeostasis GO:0019725 196 0.016
epithelium migration GO:0090132 119 0.016
gtp metabolic process GO:0046039 239 0.016
positive regulation of dendrite morphogenesis GO:0050775 3 0.016
negative regulation of immune system process GO:0002683 136 0.016
innate immune response GO:0045087 178 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
positive regulation of phosphorylation GO:0042327 394 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
tor signaling GO:0031929 39 0.015
regulation of cell growth GO:0001558 135 0.015
positive regulation of cell migration GO:0030335 172 0.015
mrna splicing via spliceosome GO:0000398 89 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
chromatin modification GO:0016568 298 0.015
cation homeostasis GO:0055080 189 0.015
regulation of response to dna damage stimulus GO:2001020 94 0.015
monovalent inorganic cation transport GO:0015672 128 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
apoptotic signaling pathway GO:0097190 268 0.015
cell adhesion GO:0007155 325 0.015
maintenance of cell polarity GO:0030011 2 0.015
positive regulation of proteolysis GO:0045862 142 0.015
oogenesis GO:0048477 2 0.015
memory GO:0007613 3 0.015
regulation of gtpase activity GO:0043087 180 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
defense response GO:0006952 315 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
tissue morphogenesis GO:0048729 96 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of rab gtpase activity GO:0032313 39 0.014
stress activated mapk cascade GO:0051403 93 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
regulation of rna splicing GO:0043484 62 0.014
actin filament based process GO:0030029 224 0.014
regulation of protein catabolic process GO:0042176 155 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
sex determination GO:0007530 3 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
regulation of growth rate GO:0040009 1 0.014
maintenance of location GO:0051235 112 0.014
positive regulation of meiotic cell cycle GO:0051446 2 0.014
microtubule based process GO:0007017 210 0.014
neural tube formation GO:0001841 3 0.014
lung alveolus development GO:0048286 4 0.014
negative regulation of transferase activity GO:0051348 124 0.014
vesicle mediated transport GO:0016192 371 0.014
protein autophosphorylation GO:0046777 123 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of cellular component size GO:0032535 82 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of response to external stimulus GO:0032101 222 0.013
cell development GO:0048468 328 0.013
positive regulation of developmental process GO:0051094 314 0.013
positive regulation of cytokine production GO:0001819 167 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
blastoderm segmentation GO:0007350 2 0.013
rhythmic behavior GO:0007622 2 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
rab protein signal transduction GO:0032482 4 0.013
negative regulation of growth GO:0045926 97 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
regulation of locomotion GO:0040012 329 0.013
regulation of multi organism process GO:0043900 157 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
rna splicing via transesterification reactions GO:0000375 90 0.013
positive regulation of cell motility GO:2000147 177 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
blastocyst development GO:0001824 3 0.013
positive regulation of viral process GO:0048524 37 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
regulation of immune response GO:0050776 201 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
regulation of protein maturation GO:1903317 150 0.013
positive regulation of transport GO:0051050 336 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of cell development GO:0060284 161 0.012
ribonucleoprotein complex assembly GO:0022618 78 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
macromolecule methylation GO:0043414 97 0.012
regulation of neurogenesis GO:0050767 82 0.012
single organism membrane organization GO:0044802 268 0.012
organ morphogenesis GO:0009887 147 0.012
response to external biotic stimulus GO:0043207 261 0.012
single organism reproductive process GO:0044702 98 0.012
generation of neurons GO:0048699 152 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
dephosphorylation GO:0016311 209 0.012
response to tumor necrosis factor GO:0034612 76 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
negative regulation of kinase activity GO:0033673 106 0.012
endosomal transport GO:0016197 129 0.012
neurological system process GO:0050877 163 0.012
behavioral response to ethanol GO:0048149 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
regulation of cell projection organization GO:0031344 107 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
neurogenesis GO:0022008 169 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of neuron projection development GO:0010975 57 0.012
cell growth GO:0016049 160 0.012
regulation of epithelial cell proliferation GO:0050678 113 0.012
single organism cell adhesion GO:0098602 179 0.012
positive regulation of immune response GO:0050778 159 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
methylation GO:0032259 106 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
rho protein signal transduction GO:0007266 26 0.012
behavior GO:0007610 112 0.012
regulation of cytokine production GO:0001817 232 0.012
response to organonitrogen compound GO:0010243 156 0.011
tube development GO:0035295 125 0.011
Fly
response to lipid GO:0033993 206 0.011
Rat
peptidyl serine modification GO:0018209 106 0.011
positive regulation of jnk cascade GO:0046330 52 0.011
myeloid cell differentiation GO:0030099 117 0.011
epithelium development GO:0060429 227 0.011
regulation of vasculature development GO:1901342 97 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
central nervous system neuron axonogenesis GO:0021955 3 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
positive regulation of transferase activity GO:0051347 227 0.011
reproductive process GO:0022414 106 0.011
response to abiotic stimulus GO:0009628 336 0.011
Rat
glycerophospholipid metabolic process GO:0006650 84 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
potassium ion transport GO:0006813 62 0.011
protein oligomerization GO:0051259 173 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
embryonic placenta development GO:0001892 1 0.011
response to decreased oxygen levels GO:0036293 96 0.011
Rat
regulation of neural precursor cell proliferation GO:2000177 4 0.011
protein deubiquitination GO:0016579 79 0.011
regulation of jnk cascade GO:0046328 73 0.011
mapk cascade GO:0000165 288 0.011
regulation of secretion GO:0051046 194 0.011
striated muscle contraction GO:0006941 52 0.011
alcohol metabolic process GO:0006066 114 0.011
regulation of cell adhesion GO:0030155 166 0.011
response to radiation GO:0009314 151 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
cell projection organization GO:0030030 252 0.011
muscle system process GO:0003012 81 0.011
circulatory system development GO:0072359 262 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
regulation of cell cycle process GO:0010564 266 0.010
nitrogen compound transport GO:0071705 191 0.010
signal release GO:0023061 70 0.010
central nervous system development GO:0007417 123 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
intracellular protein transport GO:0006886 270 0.010
positive regulation of locomotion GO:0040017 186 0.010
sequestering of metal ion GO:0051238 24 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
positive regulation of ras gtpase activity GO:0032320 117 0.010
adult locomotory behavior GO:0008344 1 0.010
hindbrain development GO:0030902 3 0.010
somitogenesis GO:0001756 2 0.010
cellular component disassembly GO:0022411 92 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.010
sensory perception GO:0007600 103 0.010
positive regulation of cell projection organization GO:0031346 64 0.010

IREB2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.083
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
muscular disease DOID:0080000 114 0.026
muscle tissue disease DOID:66 113 0.025
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
eye disease DOID:5614 149 0.023
disease of metabolism DOID:0014667 295 0.021
bone disease DOID:0080001 88 0.020
connective tissue disease DOID:65 109 0.020
myopathy DOID:423 104 0.020
neurodegenerative disease DOID:1289 102 0.013
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
immune system disease DOID:2914 155 0.012
bone development disease DOID:0080006 55 0.011
retinal disease DOID:5679 118 0.010