Homo sapiens

0 known processes

NKX6-1

NK6 homeobox 1

(Aliases: NKX6A,NKX6.1)

NKX6-1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.475
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.444
Rat
forebrain generation of neurons GO:0021872 3 0.438
cardiovascular system development GO:0072358 262 0.405
globus pallidus development GO:0021759 1 0.399
organ morphogenesis GO:0009887 147 0.359
organ formation GO:0048645 3 0.347
cell cell signaling GO:0007267 155 0.329
Rat
regulation of locomotion GO:0040012 329 0.289
Mouse
circulatory system development GO:0072359 262 0.281
nervous system development GO:0007399 293 0.267
Zebrafish Mouse Rat
regulation of cell differentiation GO:0045595 393 0.254
Mouse
cardiac cell fate determination GO:0060913 3 0.229
positive regulation of cell proliferation GO:0008284 301 0.211
cardiac right ventricle morphogenesis GO:0003215 3 0.209
positive regulation of developmental process GO:0051094 314 0.204
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.203
system process GO:0003008 349 0.196
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.191
regulation of cellular ketone metabolic process GO:0010565 50 0.190
hindbrain development GO:0030902 3 0.189
heart morphogenesis GO:0003007 48 0.181
response to oxygen containing compound GO:1901700 369 0.169
Rat
forebrain neuron differentiation GO:0021879 3 0.167
negative regulation of cell death GO:0060548 345 0.155
menstrual cycle phase GO:0022601 2 0.154
cell development GO:0048468 328 0.154
Mouse Rat
cell fate determination GO:0001709 3 0.154
regulation of cellular amino acid metabolic process GO:0006521 6 0.153
cellular ketone metabolic process GO:0042180 80 0.153
epithelium development GO:0060429 227 0.150
Zebrafish Rat
endocrine system development GO:0035270 26 0.148
Zebrafish Mouse Rat
cranial nerve development GO:0021545 4 0.143
forebrain dorsal ventral pattern formation GO:0021798 1 0.142
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.142
amine metabolic process GO:0009308 44 0.142
secretion GO:0046903 254 0.141
Rat
head development GO:0060322 108 0.138
neuron differentiation GO:0030182 138 0.137
Zebrafish Mouse
regulation of cell motility GO:2000145 299 0.136
Mouse
embryonic morphogenesis GO:0048598 85 0.135
neurogenesis GO:0022008 169 0.135
Zebrafish Mouse Rat
tube development GO:0035295 125 0.130
morphogenesis of embryonic epithelium GO:0016331 4 0.130
regulation of anatomical structure morphogenesis GO:0022603 286 0.129
Mouse
locomotory behavior GO:0007626 1 0.128
negative regulation of multicellular organismal process GO:0051241 317 0.128
Mouse
stem cell differentiation GO:0048863 93 0.123
specification of organ identity GO:0010092 3 0.123
brain development GO:0007420 97 0.123
cellular amino acid metabolic process GO:0006520 116 0.120
cellular component morphogenesis GO:0032989 314 0.120
Mouse
cellular lipid metabolic process GO:0044255 303 0.118
chemical homeostasis GO:0048878 306 0.114
metencephalon development GO:0022037 2 0.113
blood circulation GO:0008015 113 0.113
secretion by cell GO:0032940 226 0.112
Rat
extraocular skeletal muscle development GO:0002074 1 0.112
regulation of hormone levels GO:0010817 125 0.111
Rat
heart formation GO:0060914 2 0.111
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.110
spinal cord development GO:0021510 4 0.109
Zebrafish Mouse
regulation of secretion GO:0051046 194 0.108
Rat
regulation of cellular component movement GO:0051270 334 0.108
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.105
lipid metabolic process GO:0006629 381 0.102
bmp signaling pathway involved in heart development GO:0061312 3 0.101
cell morphogenesis GO:0000902 296 0.101
Mouse
negative regulation of apoptotic process GO:0043066 316 0.100
post embryonic development GO:0009791 2 0.099
cell projection organization GO:0030030 252 0.098
Mouse
amide transport GO:0042886 76 0.092
Rat
regulation of stem cell differentiation GO:2000736 56 0.091
cellular amine metabolic process GO:0044106 41 0.091
neuron projection development GO:0031175 106 0.089
Mouse
generation of neurons GO:0048699 152 0.088
Zebrafish Mouse
epithelial cell differentiation GO:0030855 141 0.085
Zebrafish Rat
forebrain regionalization GO:0021871 3 0.083
cell differentiation in spinal cord GO:0021515 1 0.082
Zebrafish Mouse
negative regulation of programmed cell death GO:0043069 321 0.082
regulation of cell migration GO:0030334 289 0.079
Mouse
tube morphogenesis GO:0035239 95 0.079
actin filament based process GO:0030029 224 0.077
regulation of cell development GO:0060284 161 0.076
Mouse
nitrogen compound transport GO:0071705 191 0.076
Rat
central nervous system development GO:0007417 123 0.075
Zebrafish Mouse
immune system development GO:0002520 195 0.074
inner ear morphogenesis GO:0042472 4 0.073
vasculature development GO:0001944 181 0.072
kidney development GO:0001822 53 0.072
regulation of secretion by cell GO:1903530 177 0.072
Rat
skeletal system development GO:0001501 79 0.070
negative regulation of cell differentiation GO:0045596 171 0.069
Mouse
positive regulation of transport GO:0051050 336 0.069
Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.068
response to hormone GO:0009725 175 0.068
Rat
peptide secretion GO:0002790 51 0.067
Rat
cellular response to endogenous stimulus GO:0071495 336 0.067
Rat
peptide hormone secretion GO:0030072 50 0.067
Rat
mesenchymal cell development GO:0014031 50 0.066
enzyme linked receptor protein signaling pathway GO:0007167 303 0.066
cardiac muscle cell contraction GO:0086003 4 0.065
positive regulation of secretion GO:0051047 116 0.063
Rat
hormone transport GO:0009914 68 0.063
Rat
stem cell development GO:0048864 69 0.063
regulation of hormone secretion GO:0046883 57 0.062
Rat
regulation of cell cycle GO:0051726 393 0.061
tissue morphogenesis GO:0048729 96 0.060
hematopoietic or lymphoid organ development GO:0048534 186 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
limbic system development GO:0021761 3 0.059
positive regulation of phosphorylation GO:0042327 394 0.058
digestive system development GO:0055123 75 0.058
regulation of kinase activity GO:0043549 314 0.057
ventral spinal cord development GO:0021517 1 0.057
Zebrafish Mouse
forebrain development GO:0030900 26 0.057
peptide transport GO:0015833 74 0.057
Rat
pattern specification process GO:0007389 43 0.057
Mouse Worm
muscle contraction GO:0006936 73 0.056
positive regulation of cell death GO:0010942 263 0.056
pancreas development GO:0031016 19 0.055
Zebrafish Mouse Rat
cell morphogenesis involved in differentiation GO:0000904 144 0.055
Mouse
neuron development GO:0048666 113 0.054
Mouse
protein localization to organelle GO:0033365 280 0.053
regulation of system process GO:0044057 101 0.053
cytoplasmic transport GO:0016482 379 0.053
cerebellum development GO:0021549 2 0.053
segmentation GO:0035282 4 0.053
transmembrane transport GO:0055085 399 0.053
positive regulation of secretion by cell GO:1903532 108 0.052
Rat
nerve development GO:0021675 4 0.052
negative regulation of developmental process GO:0051093 247 0.052
Mouse
negative regulation of cellular component movement GO:0051271 106 0.051
peripheral nervous system development GO:0007422 2 0.051
negative regulation of protein metabolic process GO:0051248 391 0.051
adult locomotory behavior GO:0008344 1 0.050
negative regulation of cellular component organization GO:0051129 235 0.050
regulation of transferase activity GO:0051338 355 0.050
heart development GO:0007507 95 0.050
actin filament based movement GO:0030048 17 0.050
negative regulation of cell proliferation GO:0008285 228 0.050
taxis GO:0042330 157 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
regulation of methylation dependent chromatin silencing GO:0090308 3 0.049
regulation of apoptotic signaling pathway GO:2001233 175 0.049
digestive tract development GO:0048565 75 0.048
embryo development GO:0009790 123 0.048
positive regulation of apoptotic process GO:0043065 246 0.048
apoptotic signaling pathway GO:0097190 268 0.048
fatty acid metabolic process GO:0006631 115 0.047
renal system development GO:0072001 63 0.046
gabaergic neuron differentiation GO:0097154 1 0.046
reproductive process GO:0022414 106 0.046
Worm
motor neuron axon guidance GO:0008045 2 0.045
cell fate commitment GO:0045165 27 0.045
Zebrafish Mouse
regulation of cellular response to stress GO:0080135 244 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
response to abiotic stimulus GO:0009628 336 0.045
inorganic ion transmembrane transport GO:0098660 231 0.045
regionalization GO:0003002 29 0.045
Mouse
cell type specific apoptotic process GO:0097285 125 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.044
paramesonephric duct development GO:0061205 2 0.044
positive regulation of cellular catabolic process GO:0031331 284 0.044
actin mediated cell contraction GO:0070252 12 0.043
negative regulation of phosphate metabolic process GO:0045936 267 0.043
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.043
cellular response to oxygen containing compound GO:1901701 276 0.043
Rat
response to wounding GO:0009611 168 0.043
regulation of cytokine production GO:0001817 232 0.043
muscle system process GO:0003012 81 0.042
regulation of cell morphogenesis GO:0022604 153 0.042
Mouse
mesenchyme development GO:0060485 59 0.042
negative regulation of catalytic activity GO:0043086 335 0.041
determination of adult lifespan GO:0008340 2 0.041
positive regulation of cell differentiation GO:0045597 211 0.041
Mouse
cytokine production GO:0001816 247 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
positive regulation of programmed cell death GO:0043068 249 0.040
signal release GO:0023061 70 0.040
Rat
blood vessel development GO:0001568 172 0.040
regulation of protein localization GO:0032880 296 0.040
oxidation reduction process GO:0055114 396 0.040
behavior GO:0007610 112 0.040
Worm
regulation of protein kinase activity GO:0045859 289 0.040
mitotic cell cycle GO:0000278 326 0.040
positive regulation of locomotion GO:0040017 186 0.040
negative regulation of cell development GO:0010721 48 0.040
Mouse
regulation of protein transport GO:0051223 213 0.039
morphogenesis of an epithelium GO:0002009 60 0.039
single organism cellular localization GO:1902580 332 0.039
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.038
anion transport GO:0006820 161 0.038
multicellular organismal aging GO:0010259 3 0.038
organophosphate catabolic process GO:0046434 430 0.037
mapk cascade GO:0000165 288 0.037
positive regulation of transferase activity GO:0051347 227 0.037
regulation of response to external stimulus GO:0032101 222 0.037
lipid biosynthetic process GO:0008610 177 0.037
cell projection morphogenesis GO:0048858 129 0.037
Mouse
intracellular protein transport GO:0006886 270 0.037
positive regulation of cellular component organization GO:0051130 376 0.037
negative regulation of protein modification process GO:0031400 200 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
embryonic camera type eye development GO:0031076 2 0.036
positive regulation of cell cycle GO:0045787 140 0.035
mesenchymal cell differentiation GO:0048762 52 0.035
regulation of membrane potential GO:0042391 95 0.035
negative regulation of locomotion GO:0040013 118 0.035
ribonucleoside catabolic process GO:0042454 406 0.035
cell part morphogenesis GO:0032990 137 0.035
Mouse
negative regulation of intracellular signal transduction GO:1902532 183 0.034
pituitary gland development GO:0021983 2 0.034
regulation of mitotic cell cycle GO:0007346 189 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
single organism reproductive process GO:0044702 98 0.034
Worm
mating GO:0007618 1 0.034
vesicle mediated transport GO:0016192 371 0.034
circulatory system process GO:0003013 113 0.033
positive regulation of catabolic process GO:0009896 310 0.033
embryonic camera type eye formation GO:0060900 2 0.033
urogenital system development GO:0001655 65 0.033
protein localization to nucleus GO:0034504 136 0.033
gland development GO:0048732 48 0.033
regulation of nervous system development GO:0051960 88 0.033
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.033
Mouse
neurological system process GO:0050877 163 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.033
small gtpase mediated signal transduction GO:0007264 78 0.033
regulation of proteolysis GO:0030162 293 0.033
embryonic epithelial tube formation GO:0001838 4 0.033
positive regulation of cell development GO:0010720 92 0.033
Mouse
blood vessel morphogenesis GO:0048514 162 0.033
membrane organization GO:0061024 292 0.032
ras protein signal transduction GO:0007265 73 0.032
regulation of peptide transport GO:0090087 62 0.032
Rat
neural crest cell development GO:0014032 3 0.032
action potential GO:0001508 34 0.032
positive regulation of protein kinase activity GO:0045860 190 0.032
muscle structure development GO:0061061 98 0.032
chemotaxis GO:0006935 157 0.032
thymus development GO:0048538 3 0.031
purine containing compound catabolic process GO:0072523 411 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
hormone secretion GO:0046879 65 0.031
Rat
purine ribonucleoside catabolic process GO:0046130 398 0.031
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
positive regulation of neural precursor cell proliferation GO:2000179 2 0.031
negative regulation of apoptotic signaling pathway GO:2001234 97 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
regulation of epithelial cell proliferation GO:0050678 113 0.031
regulation of cell cycle process GO:0010564 266 0.031
regulation of homeostatic process GO:0032844 121 0.031
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
endocrine pancreas development GO:0031018 11 0.030
Zebrafish Mouse Rat
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.030
growth GO:0040007 202 0.030
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.030
regulation of growth GO:0040008 165 0.030
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.030
organic hydroxy compound metabolic process GO:1901615 147 0.030
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
cellular homeostasis GO:0019725 196 0.030
regulation of neural precursor cell proliferation GO:2000177 4 0.030
positive regulation of mapk cascade GO:0043410 190 0.030
regulation of establishment of protein localization GO:0070201 242 0.030
regulation of epithelial to mesenchymal transition GO:0010717 37 0.029
regulation of insulin secretion GO:0050796 33 0.029
Rat
nucleoside triphosphate metabolic process GO:0009141 422 0.029
immune response GO:0006955 307 0.029
negative regulation of phosphorylation GO:0042326 174 0.029
nucleoside catabolic process GO:0009164 408 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
negative regulation of cell motility GO:2000146 104 0.029
response to biotic stimulus GO:0009607 276 0.029
regulation of peptide hormone secretion GO:0090276 41 0.029
Rat
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.028
pulmonary valve formation GO:0003193 1 0.028
carbohydrate metabolic process GO:0005975 207 0.028
inorganic cation transmembrane transport GO:0098662 194 0.028
positive regulation of cytokine production GO:0001819 167 0.028
ion homeostasis GO:0050801 230 0.028
regulation of neuron differentiation GO:0045664 70 0.028
Mouse
cellular potassium ion transport GO:0071804 60 0.028
positive regulation of epithelial cell proliferation GO:0050679 65 0.028
biological adhesion GO:0022610 331 0.028
angiogenesis GO:0001525 147 0.028
regulation of mapk cascade GO:0043408 262 0.028
positive regulation of kinase activity GO:0033674 204 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
glucose homeostasis GO:0042593 31 0.027
protein catabolic process GO:0030163 325 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
Rat
heart field specification GO:0003128 2 0.027
neuron projection morphogenesis GO:0048812 50 0.027
Mouse
luteinizing hormone secretion GO:0032275 1 0.027
embryonic organ development GO:0048568 36 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.026
positive regulation of lipid metabolic process GO:0045834 50 0.026
cell activation GO:0001775 213 0.026
phospholipid metabolic process GO:0006644 99 0.026
negative regulation of stem cell differentiation GO:2000737 22 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
blastocyst development GO:0001824 3 0.026
somatic stem cell maintenance GO:0035019 4 0.026
response to nitrogen compound GO:1901698 184 0.026
Rat
blastoderm segmentation GO:0007350 2 0.026
regulation of peptide secretion GO:0002791 42 0.026
Rat
defense response GO:0006952 315 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
negative regulation of cell migration GO:0030336 102 0.025
regulation of cell adhesion GO:0030155 166 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
protein targeting GO:0006605 187 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
potassium ion transmembrane transport GO:0071805 60 0.025
embryonic forelimb morphogenesis GO:0035115 4 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
regulation of intracellular transport GO:0032386 195 0.025
forebrain neuron development GO:0021884 2 0.025
protein maturation GO:0051604 233 0.025
mitotic cell cycle process GO:1903047 286 0.024
intrinsic apoptotic signaling pathway GO:0097193 127 0.024
ameboidal type cell migration GO:0001667 135 0.024
negative regulation of protein phosphorylation GO:0001933 140 0.024
epithelial cell proliferation GO:0050673 128 0.024
positive regulation of cell migration GO:0030335 172 0.024
cardiac atrium development GO:0003230 10 0.024
wound healing GO:0042060 115 0.024
metal ion transport GO:0030001 272 0.024
response to lipid GO:0033993 206 0.024
regulation of protein complex assembly GO:0043254 147 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
forelimb morphogenesis GO:0035136 4 0.024
copulation GO:0007620 1 0.024
regulation of ion transport GO:0043269 189 0.023
activation of protein kinase activity GO:0032147 90 0.023
nucleotide catabolic process GO:0009166 408 0.023
epithelial tube morphogenesis GO:0060562 38 0.023
cellular response to hormone stimulus GO:0032870 125 0.023
Rat
negative regulation of transport GO:0051051 176 0.023
sleep GO:0030431 2 0.023
anterior posterior axis specification GO:0009948 2 0.023
small molecule biosynthetic process GO:0044283 157 0.023
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.023
viral process GO:0016032 146 0.023
embryonic organ morphogenesis GO:0048562 24 0.023
neuromuscular junction development GO:0007528 3 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.022
regulation of lipid metabolic process GO:0019216 96 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
chordate embryonic development GO:0043009 34 0.022
single organism membrane organization GO:0044802 268 0.022
somitogenesis GO:0001756 2 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
establishment of protein localization to organelle GO:0072594 172 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
neural crest cell migration GO:0001755 2 0.022
response to alcohol GO:0097305 64 0.022
reactive oxygen species metabolic process GO:0072593 75 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
chromatin organization GO:0006325 351 0.022
wnt signaling pathway GO:0016055 156 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
regulation of neurogenesis GO:0050767 82 0.021
Mouse
positive regulation of immune system process GO:0002684 283 0.021
epidermis development GO:0008544 59 0.021
cardiac chamber development GO:0003205 30 0.021
epithelial cell migration GO:0010631 119 0.021
response to organic cyclic compound GO:0014070 204 0.021
Rat
negative regulation of cell cycle GO:0045786 193 0.021
neuroblast proliferation GO:0007405 4 0.021
response to growth factor GO:0070848 205 0.021
cell adhesion GO:0007155 325 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.021
female gamete generation GO:0007292 2 0.021
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.020
lipid transport GO:0006869 90 0.020
trophectodermal cell differentiation GO:0001829 3 0.020
interspecies interaction between organisms GO:0044419 156 0.020
steroid metabolic process GO:0008202 94 0.020
regulation of organ formation GO:0003156 4 0.020
hippocampus development GO:0021766 1 0.020
compound eye development GO:0048749 1 0.020
central nervous system neuron differentiation GO:0021953 9 0.020
Zebrafish Mouse
epithelial to mesenchymal transition GO:0001837 48 0.020
g protein coupled receptor signaling pathway GO:0007186 207 0.020
striated muscle tissue development GO:0014706 59 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
cellular chemical homeostasis GO:0055082 180 0.020
positive regulation of gliogenesis GO:0014015 4 0.019
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
pharynx development GO:0060465 1 0.019
regeneration GO:0031099 4 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
Rat
positive regulation of organelle organization GO:0010638 195 0.019
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of heart morphogenesis GO:2000826 4 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
protein oligomerization GO:0051259 173 0.019
reproductive structure development GO:0048608 55 0.019
Worm
morphogenesis of a polarized epithelium GO:0001738 3 0.019
response to organonitrogen compound GO:0010243 156 0.019
Rat
mesodermal cell fate specification GO:0007501 2 0.019
endodermal mesodermal cell signaling GO:0003133 3 0.019
leukocyte migration GO:0050900 107 0.019
multicellular organismal signaling GO:0035637 34 0.019
cellular protein catabolic process GO:0044257 261 0.019
response to cytokine GO:0034097 232 0.019
Rat
positive regulation of cellular component biogenesis GO:0044089 158 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
hematopoietic stem cell differentiation GO:0060218 4 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
regulation of ion transmembrane transport GO:0034765 132 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
protein targeting to nucleus GO:0044744 104 0.018
insulin secretion GO:0030073 39 0.018
Rat
axis elongation GO:0003401 4 0.018
reproductive system development GO:0061458 56 0.018
Worm
axonogenesis GO:0007409 31 0.018
Mouse
glycerolipid metabolic process GO:0046486 107 0.018
negative regulation of protein processing GO:0010955 142 0.018
single organism nuclear import GO:1902593 104 0.018
atrioventricular valve development GO:0003171 3 0.018
chromatin modification GO:0016568 298 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
protein import GO:0017038 130 0.018
cation transport GO:0006812 331 0.018
dna repair GO:0006281 198 0.018
organic acid biosynthetic process GO:0016053 97 0.018
microtubule based process GO:0007017 210 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
alcohol metabolic process GO:0006066 114 0.018
carbohydrate homeostasis GO:0033500 31 0.018
immune effector process GO:0002252 159 0.018
epithelium migration GO:0090132 119 0.018
intracellular receptor signaling pathway GO:0030522 104 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.018
morphogenesis of a branching structure GO:0001763 21 0.018
monosaccharide metabolic process GO:0005996 74 0.018
negative regulation of organelle organization GO:0010639 126 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
sensory organ development GO:0007423 52 0.017
embryonic eye morphogenesis GO:0048048 2 0.017
regulation of protein catabolic process GO:0042176 155 0.017
nuclear transport GO:0051169 179 0.017
glycerophospholipid metabolic process GO:0006650 84 0.017
regulation of anatomical structure size GO:0090066 101 0.017
Mouse
gtp metabolic process GO:0046039 239 0.017
nuclear import GO:0051170 106 0.017
lipid modification GO:0030258 84 0.017
av node cell to bundle of his cell communication GO:0086067 4 0.017
cardiac muscle contraction GO:0060048 34 0.017
embryonic camera type eye morphogenesis GO:0048596 2 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
Rat
cardiac left ventricle formation GO:0003218 1 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
regulation of canonical wnt signaling pathway GO:0060828 88 0.017
protein localization to membrane GO:0072657 160 0.017
cell growth GO:0016049 160 0.017
Mouse
anterior posterior axis specification embryo GO:0008595 2 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
menstruation GO:0042703 1 0.017
endomembrane system organization GO:0010256 196 0.017
second messenger mediated signaling GO:0019932 78 0.017
oogenesis GO:0048477 2 0.017
myoblast fusion GO:0007520 1 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017

NKX6-1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.081
acquired metabolic disease DOID:0060158 58 0.058
carbohydrate metabolism disease DOID:0050013 32 0.032
disease of cellular proliferation DOID:14566 174 0.023
musculoskeletal system disease DOID:17 223 0.020
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
central nervous system disease DOID:331 186 0.019
cancer DOID:162 167 0.018
diabetes mellitus DOID:9351 31 0.018
type 2 diabetes mellitus DOID:9352 28 0.018
glucose metabolism disease DOID:4194 32 0.018