Homo sapiens

0 known processes

TUBA1B

tubulin, alpha 1b

(Aliases: K-ALPHA-1)

TUBA1B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
glomerular mesangial cell development GO:0072144 1 0.993
renal interstitial fibroblast development GO:0072141 1 0.854
neuron differentiation GO:0030182 138 0.737
organelle inheritance GO:0048308 2 0.656
negative regulation of protein phosphatase type 2b activity GO:0032513 2 0.496
cytokinesis GO:0000910 96 0.486
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.458
mitotic cell cycle GO:0000278 326 0.447
kidney interstitial fibroblast differentiation GO:0072071 2 0.408
purine nucleoside monophosphate catabolic process GO:0009128 158 0.360
nucleoside monophosphate catabolic process GO:0009125 159 0.342
taxis GO:0042330 157 0.335
actin myosin filament sliding GO:0033275 6 0.330
positive regulation of protein complex disassembly GO:0043243 8 0.327
establishment or maintenance of cell polarity GO:0007163 31 0.321
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.305
mesangial cell differentiation GO:0072007 2 0.301
nervous system development GO:0007399 293 0.297
coenzyme catabolic process GO:0009109 5 0.284
ribonucleoside catabolic process GO:0042454 406 0.277
fatty acid metabolic process GO:0006631 115 0.274
mitotic nuclear division GO:0007067 119 0.259
locomotory behavior GO:0007626 1 0.241
cellular component morphogenesis GO:0032989 314 0.224
microtubule polymerization GO:0046785 18 0.223
microtubule organizing center organization GO:0031023 62 0.221
ribonucleoside monophosphate catabolic process GO:0009158 158 0.217
organelle fission GO:0048285 149 0.214
neuron development GO:0048666 113 0.207
dephosphorylation GO:0016311 209 0.207
cell projection organization GO:0030030 252 0.201
cellular macromolecule catabolic process GO:0044265 380 0.194
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.185
mitotic cell cycle process GO:1903047 286 0.175
microvillus organization GO:0032528 2 0.174
microtubule nucleation GO:0007020 6 0.171
cofactor catabolic process GO:0051187 7 0.165
microtubule cytoskeleton organization GO:0000226 176 0.157
Mouse
epithelial cell differentiation GO:0030855 141 0.154
viral life cycle GO:0019058 132 0.148
protein localization to nucleus GO:0034504 136 0.146
regulation of secretion by cell GO:1903530 177 0.144
regulation of protein secretion GO:0050708 86 0.140
carbohydrate derivative biosynthetic process GO:1901137 207 0.139
protein complex disassembly GO:0043241 52 0.139
regulation of protein phosphatase type 2b activity GO:0032512 2 0.134
neural crest cell development GO:0014032 3 0.134
positive regulation of binding GO:0051099 45 0.133
chromatin modification GO:0016568 298 0.131
ribonucleoside triphosphate catabolic process GO:0009203 391 0.127
cellular protein complex disassembly GO:0043624 36 0.127
actin filament based movement GO:0030048 17 0.127
atp metabolic process GO:0046034 176 0.126
behavior GO:0007610 112 0.123
ribonucleoside bisphosphate metabolic process GO:0033875 7 0.120
glomerulus vasculature development GO:0072012 6 0.119
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.116
adult locomotory behavior GO:0008344 1 0.114
biological adhesion GO:0022610 331 0.114
epithelial cell differentiation involved in kidney development GO:0035850 9 0.114
stem cell differentiation GO:0048863 93 0.113
microtubule based process GO:0007017 210 0.112
Mouse
post embryonic development GO:0009791 2 0.108
regulation of cell differentiation GO:0045595 393 0.107
organelle assembly GO:0070925 176 0.105
protein acylation GO:0043543 138 0.102
nucleus localization GO:0051647 1 0.102
generation of neurons GO:0048699 152 0.102
neuron migration GO:0001764 11 0.101
vesicle mediated transport GO:0016192 371 0.100
regulation of nucleotide metabolic process GO:0006140 269 0.099
neurogenesis GO:0022008 169 0.098
anion transport GO:0006820 161 0.098
cell part morphogenesis GO:0032990 137 0.098
macromolecular complex disassembly GO:0032984 60 0.097
negative regulation of cell size GO:0045792 3 0.096
nuclear division GO:0000280 128 0.095
spindle assembly GO:0051225 29 0.095
skeletal myofibril assembly GO:0014866 3 0.095
neuromuscular junction development GO:0007528 3 0.094
regulation of ion transmembrane transporter activity GO:0032412 72 0.093
blood circulation GO:0008015 113 0.091
response to virus GO:0009615 126 0.090
positive regulation of transport GO:0051050 336 0.090
positive regulation of cellular amine metabolic process GO:0033240 7 0.087
viral process GO:0016032 146 0.084
regulation of establishment of protein localization GO:0070201 242 0.083
regulation of protein transport GO:0051223 213 0.081
internal protein amino acid acetylation GO:0006475 101 0.080
multi organism cellular process GO:0044764 156 0.079
nucleoside triphosphate metabolic process GO:0009141 422 0.078
covalent chromatin modification GO:0016569 254 0.076
oocyte development GO:0048599 1 0.074
negative regulation of phosphate metabolic process GO:0045936 267 0.072
secretion by cell GO:0032940 226 0.072
ribonucleoside triphosphate metabolic process GO:0009199 412 0.071
purine ribonucleotide catabolic process GO:0009154 404 0.070
atp dependent chromatin remodeling GO:0043044 25 0.069
purine nucleoside catabolic process GO:0006152 398 0.067
negative regulation of hydrolase activity GO:0051346 182 0.067
cell morphogenesis involved in differentiation GO:0000904 144 0.067
cell development GO:0048468 328 0.067
meiotic chromosome segregation GO:0045132 4 0.065
meiosis i GO:0007127 4 0.063
dna repair GO:0006281 198 0.063
platelet activation GO:0030168 44 0.063
cellular lipid metabolic process GO:0044255 303 0.062
negative regulation of organelle organization GO:0010639 126 0.062
carboxylic acid biosynthetic process GO:0046394 97 0.059
skeletal muscle thin filament assembly GO:0030240 3 0.059
cytoplasmic transport GO:0016482 379 0.059
cofactor biosynthetic process GO:0051188 31 0.055
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.054
positive regulation of gtpase activity GO:0043547 166 0.053
oogenesis GO:0048477 2 0.053
positive regulation of nucleotide metabolic process GO:0045981 230 0.052
mitotic cytokinesis GO:0000281 19 0.052
axonogenesis GO:0007409 31 0.052
cellular protein complex assembly GO:0043623 188 0.051
positive regulation of transferase activity GO:0051347 227 0.051
nucleoside catabolic process GO:0009164 408 0.051
positive regulation of secretion GO:0051047 116 0.050
protein localization to organelle GO:0033365 280 0.050
ribonucleoside monophosphate metabolic process GO:0009161 187 0.050
cellular macromolecular complex assembly GO:0034622 324 0.049
regulation of cell cycle process GO:0010564 266 0.049
somatic muscle development GO:0007525 1 0.047
long chain fatty acid metabolic process GO:0001676 30 0.045
ribonucleoprotein complex assembly GO:0022618 78 0.045
cardiac muscle contraction GO:0060048 34 0.043
amine metabolic process GO:0009308 44 0.042
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.042
cell morphogenesis GO:0000902 296 0.042
tissue homeostasis GO:0001894 63 0.042
dendritic spine morphogenesis GO:0060997 3 0.041
endoplasmic reticulum organization GO:0007029 20 0.041
regulation of nucleotide catabolic process GO:0030811 205 0.041
establishment of nucleus localization GO:0040023 1 0.041
positive regulation of developmental process GO:0051094 314 0.041
cellular response to acid chemical GO:0071229 44 0.041
atp catabolic process GO:0006200 157 0.041
ribonucleotide biosynthetic process GO:0009260 81 0.040
regulation of viral process GO:0050792 103 0.040
stem cell development GO:0048864 69 0.040
cellular response to oxidative stress GO:0034599 85 0.039
positive regulation of organelle organization GO:0010638 195 0.039
organophosphate catabolic process GO:0046434 430 0.039
interspecies interaction between organisms GO:0044419 156 0.038
mesenchymal cell development GO:0014031 50 0.038
histone acetylation GO:0016573 93 0.038
regulation of phosphatase activity GO:0010921 81 0.037
purine nucleotide biosynthetic process GO:0006164 84 0.037
chemotaxis GO:0006935 157 0.036
coenzyme a metabolic process GO:0015936 6 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
internal peptidyl lysine acetylation GO:0018393 97 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.036
microvillus assembly GO:0030033 2 0.034
protein secretion GO:0009306 98 0.033
organophosphate biosynthetic process GO:0090407 163 0.033
maintenance of location GO:0051235 112 0.033
axon development GO:0061564 34 0.032
actin filament organization GO:0007015 128 0.032
ubiquitin dependent protein catabolic process GO:0006511 206 0.032
ribonucleoprotein complex biogenesis GO:0022613 116 0.032
positive regulation of protein transport GO:0051222 135 0.031
lipid biosynthetic process GO:0008610 177 0.031
protein import into nucleus GO:0006606 104 0.031
spindle organization GO:0007051 53 0.031
dna packaging GO:0006323 77 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
cytokinetic process GO:0032506 12 0.030
ribonucleotide catabolic process GO:0009261 405 0.030
phospholipid metabolic process GO:0006644 99 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.030
negative regulation of apoptotic process GO:0043066 316 0.029
spermatid differentiation GO:0048515 4 0.029
cell differentiation involved in kidney development GO:0061005 9 0.029
negative regulation of phosphatase activity GO:0010923 61 0.029
actin cytoskeleton organization GO:0030036 207 0.029
axon cargo transport GO:0008088 2 0.028
regulation of cell growth GO:0001558 135 0.028
mitotic spindle organization GO:0007052 27 0.028
mrna metabolic process GO:0016071 175 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
regulation of binding GO:0051098 111 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
purine nucleoside monophosphate metabolic process GO:0009126 186 0.027
lipid metabolic process GO:0006629 381 0.027
cellular response to cytokine stimulus GO:0071345 181 0.027
Mouse
rna splicing GO:0008380 131 0.027
double strand break repair GO:0006302 101 0.027
chromatin remodeling GO:0006338 55 0.027
protein targeting to nucleus GO:0044744 104 0.027
coenzyme metabolic process GO:0006732 65 0.027
immune effector process GO:0002252 159 0.026
regulation of dephosphorylation GO:0035303 96 0.026
anterior posterior axis specification GO:0009948 2 0.026
negative regulation of cellular catabolic process GO:0031330 83 0.026
regulation of intracellular protein transport GO:0033157 123 0.026
response to external biotic stimulus GO:0043207 261 0.026
cellular metal ion homeostasis GO:0006875 146 0.026
viral genome replication GO:0019079 50 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
cell activation GO:0001775 213 0.025
mesenchyme development GO:0060485 59 0.025
regulation of intracellular transport GO:0032386 195 0.024
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
renal system development GO:0072001 63 0.024
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.024
striated muscle myosin thick filament assembly GO:0071688 2 0.024
determination of adult lifespan GO:0008340 2 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
carbohydrate metabolic process GO:0005975 207 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
multicellular organismal aging GO:0010259 3 0.023
negative regulation of catabolic process GO:0009895 104 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
regulation of mrna splicing via spliceosome GO:0048024 32 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.022
spermatid development GO:0007286 4 0.022
phospholipid biosynthetic process GO:0008654 44 0.022
response to other organism GO:0051707 261 0.022
ribonucleoside bisphosphate biosynthetic process GO:0034030 4 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
nuclear import GO:0051170 106 0.021
development of primary sexual characteristics GO:0045137 35 0.021
cell division GO:0051301 168 0.021
negative regulation of cell death GO:0060548 345 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of atp metabolic process GO:1903578 29 0.021
fertilization GO:0009566 12 0.021
gonad development GO:0008406 34 0.021
circulatory system process GO:0003013 113 0.021
chromatin organization GO:0006325 351 0.020
regulation of ligase activity GO:0051340 29 0.020
positive regulation of protein depolymerization GO:1901881 6 0.020
positive regulation of protein secretion GO:0050714 60 0.020
cellular component disassembly GO:0022411 92 0.020
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.020
receptor mediated endocytosis GO:0006898 84 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
long chain fatty acyl coa metabolic process GO:0035336 5 0.019
female gamete generation GO:0007292 2 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
cranial nerve development GO:0021545 4 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
nucleoside bisphosphate metabolic process GO:0033865 7 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
response to metal ion GO:0010038 84 0.019
regulation of protein targeting GO:1903533 91 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
transmembrane transport GO:0055085 399 0.019
small gtpase mediated signal transduction GO:0007264 78 0.018
neural nucleus development GO:0048857 47 0.018
negative regulation of protein complex assembly GO:0031333 43 0.018
dna recombination GO:0006310 77 0.018
transcription coupled nucleotide excision repair GO:0006283 8 0.018
regulation of actin cytoskeleton organization GO:0032956 116 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
single fertilization GO:0007338 11 0.018
organ morphogenesis GO:0009887 147 0.018
blood vessel development GO:0001568 172 0.018
regulation of actin filament depolymerization GO:0030834 10 0.017
rna catabolic process GO:0006401 71 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
deoxyribose phosphate metabolic process GO:0019692 6 0.017
single organism nuclear import GO:1902593 104 0.017
centrosome organization GO:0051297 58 0.016
head development GO:0060322 108 0.016
cell projection morphogenesis GO:0048858 129 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
cytoskeleton dependent cytokinesis GO:0061640 22 0.016
deoxyribonucleotide metabolic process GO:0009262 6 0.016
establishment of spindle orientation GO:0051294 9 0.016
recombinational repair GO:0000725 50 0.016
chemical homeostasis GO:0048878 306 0.016
protein k63 linked ubiquitination GO:0070534 31 0.015
purine containing compound catabolic process GO:0072523 411 0.015
necrotic cell death GO:0070265 21 0.015
neural tube formation GO:0001841 3 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
regulation of protein localization GO:0032880 296 0.015
protein localization to chromosome GO:0034502 30 0.015
actin filament based process GO:0030029 224 0.015
mitochondrial calcium ion homeostasis GO:0051560 11 0.015
free ubiquitin chain polymerization GO:0010994 2 0.015
system process GO:0003008 349 0.015
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.015
positive regulation of protein ubiquitination GO:0031398 53 0.015
mapk cascade GO:0000165 288 0.015
actin polymerization or depolymerization GO:0008154 56 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
actomyosin structure organization GO:0031032 59 0.014
regulation of secretion GO:0051046 194 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
calcium ion transmembrane transport GO:0070588 76 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
regulation of cell division GO:0051302 116 0.014
binding of sperm to zona pellucida GO:0007339 3 0.014
glucose metabolic process GO:0006006 45 0.014
heart process GO:0003015 62 0.014
cellular amine metabolic process GO:0044106 41 0.014
vacuole organization GO:0007033 44 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
regulation of dna damage checkpoint GO:2000001 9 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
single organism reproductive process GO:0044702 98 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
organic acid biosynthetic process GO:0016053 97 0.013
sensory perception of temperature stimulus GO:0050951 1 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
multicellular organismal response to stress GO:0033555 1 0.013
small molecule biosynthetic process GO:0044283 157 0.013
endocytosis GO:0006897 159 0.013
nuclear transport GO:0051169 179 0.013
protein dna complex assembly GO:0065004 64 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
regulation of protein depolymerization GO:1901879 22 0.013
homotypic cell cell adhesion GO:0034109 47 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
centrosome duplication GO:0051298 28 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
response to oxygen containing compound GO:1901700 369 0.012
cellular chemical homeostasis GO:0055082 180 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
nucleoside biosynthetic process GO:0009163 26 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
cell cell signaling GO:0007267 155 0.012
dna conformation change GO:0071103 113 0.012
axon guidance GO:0007411 12 0.012
establishment of ribosome localization GO:0033753 4 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
cellular ketone metabolic process GO:0042180 80 0.012
positive regulation of viral process GO:0048524 37 0.012
cell projection assembly GO:0030031 126 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.012
cranial nerve morphogenesis GO:0021602 1 0.012
anatomical structure homeostasis GO:0060249 100 0.012
rna transport GO:0050658 39 0.012
intracellular protein transport GO:0006886 270 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
reproductive process GO:0022414 106 0.012
cellular biogenic amine metabolic process GO:0006576 34 0.012
histone exchange GO:0043486 3 0.011
regulation of cell cycle GO:0051726 393 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
purine ribonucleoside biosynthetic process GO:0046129 23 0.011
rna interference GO:0016246 4 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
central nervous system development GO:0007417 123 0.011
nuclear migration GO:0007097 1 0.011
regulation of cell activation GO:0050865 125 0.011
peptidyl proline modification GO:0018208 15 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
maintenance of protein location in cell GO:0032507 56 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
t cell proliferation GO:0042098 45 0.011
histone modification GO:0016570 251 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
single organism cellular localization GO:1902580 332 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.011
regulation of microtubule polymerization GO:0031113 12 0.011
cell adhesion GO:0007155 325 0.011
regulation of meiosis GO:0040020 3 0.011
cellular response to organonitrogen compound GO:0071417 124 0.010
ncrna 3 end processing GO:0043628 4 0.010
nucleoside bisphosphate biosynthetic process GO:0033866 4 0.010
cranial nerve formation GO:0021603 1 0.010
regulation of protein processing GO:0070613 150 0.010
glycoprotein metabolic process GO:0009100 110 0.010
ribosomal subunit export from nucleus GO:0000054 4 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010
negative regulation of cytoplasmic transport GO:1903650 46 0.010
maintenance of location in cell GO:0051651 62 0.010
long chain fatty acid biosynthetic process GO:0042759 4 0.010
response to light stimulus GO:0009416 87 0.010
peptidyl lysine modification GO:0018205 144 0.010
gene silencing GO:0016458 49 0.010

TUBA1B disease predictions

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 53 0.150
autosomal dominant nonsyndromic deafness DOID:0050564 23 0.150
nonsyndromic deafness DOID:0050563 50 0.150
sensory system disease DOID:0050155 203 0.150
nervous system disease DOID:863 431 0.150
central nervous system disease DOID:331 186 0.027
neurodegenerative disease DOID:1289 102 0.020