Homo sapiens

247 known processes

ARFGEF1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

(Aliases: BIG1,ARFGEP1,P200,DKFZP434L057,D730028O18Rik)

ARFGEF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rho gtpase activity GO:0034259 4 0.997
rho protein signal transduction GO:0007266 26 0.984
nucleoside catabolic process GO:0009164 408 0.943
positive regulation of gtpase activity GO:0043547 166 0.924
gtp catabolic process GO:0006184 237 0.912
macromolecule glycosylation GO:0043413 63 0.909
gtp metabolic process GO:0046039 239 0.889
glycoprotein biosynthetic process GO:0009101 91 0.887
regulation of gtpase activity GO:0043087 180 0.876
guanosine containing compound metabolic process GO:1901068 244 0.859
regulation of rho gtpase activity GO:0032319 66 0.855
purine nucleoside catabolic process GO:0006152 398 0.851
nucleotide catabolic process GO:0009166 408 0.849
guanosine containing compound catabolic process GO:1901069 239 0.848
organophosphate catabolic process GO:0046434 430 0.843
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.833
purine ribonucleoside catabolic process GO:0046130 398 0.830
endosome organization GO:0007032 20 0.830
Human
regulation of gtp catabolic process GO:0033124 180 0.825
ras protein signal transduction GO:0007265 73 0.819
ribonucleotide catabolic process GO:0009261 405 0.818
single organism carbohydrate metabolic process GO:0044723 193 0.812
ribonucleoside catabolic process GO:0042454 406 0.808
carbohydrate metabolic process GO:0005975 207 0.803
regulation of establishment of cell polarity GO:2000114 5 0.800
glycosyl compound catabolic process GO:1901658 413 0.791
glycosylation GO:0070085 71 0.749
regulation of rho protein signal transduction GO:0035023 79 0.748
regulation of ras gtpase activity GO:0032318 128 0.736
ribonucleoside triphosphate metabolic process GO:0009199 412 0.730
small gtpase mediated signal transduction GO:0007264 78 0.722
positive regulation of glycoprotein biosynthetic process GO:0010560 6 0.718
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.715
regulation of carbohydrate metabolic process GO:0006109 54 0.703
ribonucleoside triphosphate catabolic process GO:0009203 391 0.690
positive regulation of cytokine production GO:0001819 167 0.682
Human
regulation of nucleotide catabolic process GO:0030811 205 0.682
purine nucleoside triphosphate metabolic process GO:0009144 412 0.680
purine ribonucleotide catabolic process GO:0009154 404 0.670
positive regulation of catabolic process GO:0009896 310 0.666
regulation of purine nucleotide metabolic process GO:1900542 264 0.656
regulation of ras protein signal transduction GO:0046578 155 0.652
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.647
Human
cellular carbohydrate metabolic process GO:0044262 84 0.641
cytoplasmic transport GO:0016482 379 0.635
Human
regulation of nucleoside metabolic process GO:0009118 209 0.628
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.628
regulation of nucleotide metabolic process GO:0006140 269 0.626
cellular macromolecular complex assembly GO:0034622 324 0.619
positive regulation of nucleotide catabolic process GO:0030813 185 0.616
regulation of small gtpase mediated signal transduction GO:0051056 156 0.613
negative regulation of phosphate metabolic process GO:0045936 267 0.600
endomembrane system organization GO:0010256 196 0.574
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.567
Human
regulation of protein glycosylation GO:0060049 6 0.547
cytokine production GO:0001816 247 0.541
Human
nucleoside phosphate catabolic process GO:1901292 412 0.537
regulation of protein polymerization GO:0032271 63 0.530
positive regulation of cellular catabolic process GO:0031331 284 0.528
actin cytoskeleton organization GO:0030036 207 0.509
carbohydrate derivative biosynthetic process GO:1901137 207 0.503
actin filament organization GO:0007015 128 0.491
positive regulation of nucleotide metabolic process GO:0045981 230 0.484
regulation of wound healing GO:0061041 56 0.475
post embryonic development GO:0009791 2 0.461
Worm
negative regulation of ras gtpase activity GO:0034261 6 0.444
protein glycosylation in golgi GO:0033578 3 0.430
purine containing compound catabolic process GO:0072523 411 0.429
nucleoside triphosphate catabolic process GO:0009143 394 0.428
regulation of tumor necrosis factor production GO:0032680 43 0.427
Human
positive regulation of glycoprotein metabolic process GO:1903020 8 0.427
purine nucleoside triphosphate catabolic process GO:0009146 392 0.414
negative regulation of phosphorus metabolic process GO:0010563 267 0.409
regulation of cytoskeleton organization GO:0051493 177 0.409
positive regulation of hydrolase activity GO:0051345 331 0.408
positive regulation of tumor necrosis factor production GO:0032760 21 0.398
Human
regulation of establishment or maintenance of cell polarity GO:0032878 7 0.392
regulation of cytokine production GO:0001817 232 0.387
Human
regulation of cellular component biogenesis GO:0044087 281 0.384
establishment of cell polarity GO:0030010 22 0.370
negative regulation of actin filament polymerization GO:0030837 10 0.364
tumor necrosis factor production GO:0032640 43 0.350
Human
regulation of glycoprotein metabolic process GO:1903018 19 0.338
regulation of anatomical structure size GO:0090066 101 0.328
actin filament polymerization GO:0030041 45 0.308
negative regulation of catalytic activity GO:0043086 335 0.308
negative regulation of protein polymerization GO:0032272 16 0.298
female gamete generation GO:0007292 2 0.298
regulation of protein complex assembly GO:0043254 147 0.288
receptor metabolic process GO:0043112 81 0.287
Human
positive regulation of carbohydrate metabolic process GO:0045913 21 0.280
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.275
Human
negative regulation of catabolic process GO:0009895 104 0.273
positive regulation of cellular component organization GO:0051130 376 0.264
negative regulation of cellular component organization GO:0051129 235 0.259
actin filament based process GO:0030029 224 0.251
covalent chromatin modification GO:0016569 254 0.248
neural tube formation GO:0001841 3 0.240
regulation of actin filament polymerization GO:0030833 50 0.239
cellular protein complex assembly GO:0043623 188 0.237
regulation of cellular component size GO:0032535 82 0.224
regulation of response to wounding GO:1903034 101 0.217
golgi vesicle transport GO:0048193 80 0.216
Human
negative regulation of organelle organization GO:0010639 126 0.214
negative regulation of hydrolase activity GO:0051346 182 0.213
negative regulation of cytoskeleton organization GO:0051494 45 0.194
vesicle mediated transport GO:0016192 371 0.190
Human Worm
system process GO:0003008 349 0.187
positive regulation of response to wounding GO:1903036 28 0.172
response to wounding GO:0009611 168 0.172
histone modification GO:0016570 251 0.169
morphogenesis of embryonic epithelium GO:0016331 4 0.164
secretion by cell GO:0032940 226 0.163
post golgi vesicle mediated transport GO:0006892 36 0.161
Human
positive regulation of developmental process GO:0051094 314 0.156
mitochondrion organization GO:0007005 156 0.155
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.142
negative regulation of nucleotide catabolic process GO:0030812 16 0.135
regulation of glycoprotein biosynthetic process GO:0010559 14 0.133
regulation of actin filament based process GO:0032970 141 0.132
endosomal transport GO:0016197 129 0.131
negative regulation of nucleotide metabolic process GO:0045980 29 0.121
negative regulation of cellular catabolic process GO:0031330 83 0.120
cellular chemical homeostasis GO:0055082 180 0.115
membrane organization GO:0061024 292 0.109
Worm
exocytosis GO:0006887 71 0.107
peptidyl serine phosphorylation GO:0018105 101 0.105
negative regulation of protein complex assembly GO:0031333 43 0.103
regulation of growth GO:0040008 165 0.102
long term memory GO:0007616 2 0.100
memory GO:0007613 3 0.095
establishment or maintenance of cell polarity GO:0007163 31 0.092
oocyte development GO:0048599 1 0.090
oogenesis GO:0048477 2 0.089
regulation of actin filament length GO:0030832 56 0.088
engulfment of apoptotic cell GO:0043652 2 0.085
Worm
secretion GO:0046903 254 0.085
locomotory behavior GO:0007626 1 0.084
positive regulation of protein phosphorylation GO:0001934 313 0.082
response to abiotic stimulus GO:0009628 336 0.081
tripartite regional subdivision GO:0007351 2 0.081
positive regulation of ras gtpase activity GO:0032320 117 0.081
neurological system process GO:0050877 163 0.080
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.079
ubiquitin dependent protein catabolic process GO:0006511 206 0.078
chromatin organization GO:0006325 351 0.077
nucleoside triphosphate metabolic process GO:0009141 422 0.076
anterior posterior axis specification GO:0009948 2 0.076
enzyme linked receptor protein signaling pathway GO:0007167 303 0.076
golgi to plasma membrane transport GO:0006893 21 0.075
Human
positive regulation of transport GO:0051050 336 0.075
regulation of anatomical structure morphogenesis GO:0022603 286 0.073
spermatid differentiation GO:0048515 4 0.073
tube development GO:0035295 125 0.072
embryo development GO:0009790 123 0.070
Worm
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.070
cell development GO:0048468 328 0.070
embryonic epithelial tube formation GO:0001838 4 0.069
protein deacylation GO:0035601 39 0.066
nucleus localization GO:0051647 1 0.066
chromatin modification GO:0016568 298 0.066
cellular response to dna damage stimulus GO:0006974 379 0.065
mapk cascade GO:0000165 288 0.065
regulation of dna metabolic process GO:0051052 153 0.064
positive regulation of phosphorylation GO:0042327 394 0.064
peptidyl serine modification GO:0018209 106 0.063
oocyte differentiation GO:0009994 2 0.063
negative regulation of protein polyubiquitination GO:1902915 4 0.062
spermatid development GO:0007286 4 0.062
response to biotic stimulus GO:0009607 276 0.062
cellular homeostasis GO:0019725 196 0.061
signal transduction by phosphorylation GO:0023014 297 0.061
phagocytosis GO:0006909 42 0.060
Worm
protein glycosylation GO:0006486 62 0.060
developmental growth GO:0048589 48 0.060
tube morphogenesis GO:0035239 95 0.059
mitotic cell cycle GO:0000278 326 0.058
determination of adult lifespan GO:0008340 2 0.058
epithelium migration GO:0090132 119 0.057
protein localization to membrane GO:0072657 160 0.057
response to oxygen containing compound GO:1901700 369 0.054
behavioral response to ethanol GO:0048149 2 0.053
regulation of canonical wnt signaling pathway GO:0060828 88 0.053
camp metabolic process GO:0046058 61 0.053
heart development GO:0007507 95 0.052
single organism cellular localization GO:1902580 332 0.051
establishment of protein localization to organelle GO:0072594 172 0.050
canonical wnt signaling pathway GO:0060070 116 0.050
protein localization to organelle GO:0033365 280 0.049
nervous system development GO:0007399 293 0.049
lipid localization GO:0010876 106 0.049
oxidation reduction process GO:0055114 396 0.047
establishment of nucleus localization GO:0040023 1 0.047
positive regulation of organelle organization GO:0010638 195 0.046
ion transmembrane transport GO:0034220 338 0.046
single organism membrane organization GO:0044802 268 0.046
circulatory system development GO:0072359 262 0.045
neuron differentiation GO:0030182 138 0.045
purine ribonucleoside metabolic process GO:0046128 437 0.044
regulation of cell cycle GO:0051726 393 0.043
cognition GO:0050890 43 0.043
regulation of purine nucleotide catabolic process GO:0033121 205 0.042
positive regulation of protein kinase activity GO:0045860 190 0.042
protein catabolic process GO:0030163 325 0.042
positive regulation of nucleoside metabolic process GO:0045979 186 0.042
generation of neurons GO:0048699 152 0.042
negative regulation of cell cycle GO:0045786 193 0.041
transmembrane transport GO:0055085 399 0.041
negative regulation of cell cycle process GO:0010948 121 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.040
positive regulation of transferase activity GO:0051347 227 0.039
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.037
primary neural tube formation GO:0014020 3 0.037
organelle localization GO:0051640 84 0.036
ameboidal type cell migration GO:0001667 135 0.036
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.036
organ morphogenesis GO:0009887 147 0.035
regulation of transferase activity GO:0051338 355 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
cation homeostasis GO:0055080 189 0.035
single organism reproductive process GO:0044702 98 0.035
intracellular mrna localization GO:0008298 1 0.034
cell projection organization GO:0030030 252 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
multicellular organismal aging GO:0010259 3 0.034
cardiovascular system development GO:0072358 262 0.034
tissue migration GO:0090130 119 0.034
neuroblast proliferation GO:0007405 4 0.033
protein autophosphorylation GO:0046777 123 0.033
segmentation GO:0035282 4 0.033
response to other organism GO:0051707 261 0.033
glucosamine containing compound metabolic process GO:1901071 10 0.033
mitochondrion distribution GO:0048311 3 0.032
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.032
protein processing GO:0016485 226 0.032
positive regulation of kinase activity GO:0033674 204 0.032
neuron projection development GO:0031175 106 0.032
positive regulation of growth GO:0045927 58 0.031
dna repair GO:0006281 198 0.031
regulation of cell cycle process GO:0010564 266 0.031
cell cell signaling GO:0007267 155 0.031
response to dietary excess GO:0002021 2 0.031
intracellular protein transport GO:0006886 270 0.031
negative regulation of protein metabolic process GO:0051248 391 0.030
positive regulation of cell differentiation GO:0045597 211 0.029
chemical homeostasis GO:0048878 306 0.029
cellular cation homeostasis GO:0030003 163 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
protein deacetylation GO:0006476 38 0.029
regulation of protein localization GO:0032880 296 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
behavior GO:0007610 112 0.029
negative regulation of cell differentiation GO:0045596 171 0.028
glycoprotein metabolic process GO:0009100 110 0.028
rab protein signal transduction GO:0032482 4 0.028
response to radiation GO:0009314 151 0.028
maintenance of location GO:0051235 112 0.028
myosin filament assembly GO:0031034 2 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
double strand break repair GO:0006302 101 0.028
regulation of mapk cascade GO:0043408 262 0.027
regulation of chromosome organization GO:0033044 103 0.027
reactive oxygen species biosynthetic process GO:1903409 4 0.026
internal peptidyl lysine acetylation GO:0018393 97 0.026
photoreceptor cell differentiation GO:0046530 2 0.026
neural tube closure GO:0001843 3 0.026
cell division GO:0051301 168 0.026
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.026
regulation of cellular response to stress GO:0080135 244 0.026
peptidyl lysine acetylation GO:0018394 101 0.026
negative regulation of gtpase activity GO:0034260 11 0.026
dephosphorylation GO:0016311 209 0.025
jnk cascade GO:0007254 80 0.025
response to bacterium GO:0009617 144 0.025
protein import GO:0017038 130 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
response to external biotic stimulus GO:0043207 261 0.025
single organism behavior GO:0044708 28 0.025
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.024
positive regulation of developmental growth GO:0048639 16 0.024
embryonic viscerocranium morphogenesis GO:0048703 1 0.024
cell cycle checkpoint GO:0000075 117 0.024
rhythmic behavior GO:0007622 2 0.024
cellular component morphogenesis GO:0032989 314 0.024
cellular response to abiotic stimulus GO:0071214 117 0.023
positive regulation of cell cycle GO:0045787 140 0.023
limbic system development GO:0021761 3 0.023
neuron development GO:0048666 113 0.023
regulation of rab gtpase activity GO:0032313 39 0.023
negative regulation of protein processing GO:0010955 142 0.023
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
brain development GO:0007420 97 0.022
ion homeostasis GO:0050801 230 0.022
hindbrain development GO:0030902 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.022
regulation of protein kinase activity GO:0045859 289 0.022
regulation of dna replication GO:0006275 68 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
regulation of cell development GO:0060284 161 0.021
cellular ketone metabolic process GO:0042180 80 0.021
chemotaxis GO:0006935 157 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
neuromuscular junction development GO:0007528 3 0.021
nuclear migration GO:0007097 1 0.021
mitotic nuclear division GO:0007067 119 0.021
regulation of rab protein signal transduction GO:0032483 39 0.020
epithelial cell migration GO:0010631 119 0.020
cellular amine metabolic process GO:0044106 41 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
cellular response to radiation GO:0071478 65 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
protein oligomerization GO:0051259 173 0.020
axon cargo transport GO:0008088 2 0.020
cation transport GO:0006812 331 0.020
positive regulation of cell size GO:0045793 3 0.020
regulation of mitotic cell cycle phase transition GO:1901990 118 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
regulation of protein maturation GO:1903317 150 0.019
nuclear transport GO:0051169 179 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
histone acetylation GO:0016573 93 0.019
positive regulation of map kinase activity GO:0043406 80 0.019
tube closure GO:0060606 3 0.019
glycerolipid metabolic process GO:0046486 107 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
central nervous system neuron axonogenesis GO:0021955 3 0.019
organelle fission GO:0048285 149 0.019
regulation of cell differentiation GO:0045595 393 0.018
regulation of developmental growth GO:0048638 30 0.018
regulation of multi organism process GO:0043900 157 0.018
macromolecule deacylation GO:0098732 41 0.018
protein homooligomerization GO:0051260 100 0.018
regulation of protein targeting GO:1903533 91 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
adult behavior GO:0030534 18 0.018
lipid storage GO:0019915 28 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
regulation of protein processing GO:0070613 150 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
meiosis i GO:0007127 4 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
regulation of protein transport GO:0051223 213 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
apoptotic signaling pathway GO:0097190 268 0.017
biological adhesion GO:0022610 331 0.017
wnt signaling pathway GO:0016055 156 0.017
immune response GO:0006955 307 0.017
protein acetylation GO:0006473 116 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
regulation of cell adhesion GO:0030155 166 0.017
positive regulation of mapk cascade GO:0043410 190 0.017
growth GO:0040007 202 0.017
ribonucleoprotein complex subunit organization GO:0071826 81 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
sensory perception of sound GO:0007605 37 0.017
negative regulation of phosphatase activity GO:0010923 61 0.017
negative regulation of cell death GO:0060548 345 0.017
monovalent inorganic cation transport GO:0015672 128 0.016
epithelial cell proliferation GO:0050673 128 0.016
regulation of multicellular organism growth GO:0040014 8 0.016
response to molecule of bacterial origin GO:0002237 82 0.016
cell cycle phase transition GO:0044770 173 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
adult locomotory behavior GO:0008344 1 0.016
protein targeting to nucleus GO:0044744 104 0.016
cell growth GO:0016049 160 0.016
peptidyl threonine modification GO:0018210 45 0.016
endocytosis GO:0006897 159 0.016
Worm
cell adhesion GO:0007155 325 0.016
microtubule based process GO:0007017 210 0.016
positive regulation of cell growth GO:0030307 48 0.016
tissue morphogenesis GO:0048729 96 0.015
organelle assembly GO:0070925 176 0.015
cellular lipid metabolic process GO:0044255 303 0.015
regulation of triglyceride metabolic process GO:0090207 11 0.015
reproductive process GO:0022414 106 0.015
rna localization GO:0006403 41 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
synaptic transmission GO:0007268 61 0.015
embryo development ending in birth or egg hatching GO:0009792 34 0.015
Worm
central nervous system development GO:0007417 123 0.015
regulation of protein ubiquitination GO:0031396 95 0.015
phagocytosis engulfment GO:0006911 7 0.015
Worm
protein maturation GO:0051604 233 0.015
alcohol metabolic process GO:0006066 114 0.015
axis elongation GO:0003401 4 0.015
negative regulation of protein modification process GO:0031400 200 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
regulation of protein glycosylation in golgi GO:0090283 3 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
immune effector process GO:0002252 159 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
receptor mediated endocytosis GO:0006898 84 0.014
Worm
regulation of cell growth GO:0001558 135 0.014
negative regulation of proteolysis GO:0045861 132 0.014
regulation of epithelial cell migration GO:0010632 93 0.014
regulation of peptidyl serine phosphorylation GO:0033135 50 0.014
regulation of immune response GO:0050776 201 0.014
carbohydrate transport GO:0008643 37 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of cellular component movement GO:0051270 334 0.014
heart morphogenesis GO:0003007 48 0.014
protein targeting GO:0006605 187 0.014
calcium ion homeostasis GO:0055074 122 0.014
regulation of locomotion GO:0040012 329 0.014
embryonic digestive tract morphogenesis GO:0048557 2 0.014
regulation of tor signaling GO:0032006 30 0.014
regulation of response to external stimulus GO:0032101 222 0.014
nuclear division GO:0000280 128 0.014
single organism nuclear import GO:1902593 104 0.014
atp catabolic process GO:0006200 157 0.014
cellular amide metabolic process GO:0043603 69 0.014
establishment of organelle localization GO:0051656 59 0.014
cell part morphogenesis GO:0032990 137 0.014
regulation of proteolysis GO:0030162 293 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
regulation of endocytosis GO:0030100 72 0.013
regulation of camp metabolic process GO:0030814 52 0.013
cellular response to molecule of bacterial origin GO:0071219 62 0.013
response to virus GO:0009615 126 0.013
peptidyl threonine phosphorylation GO:0018107 41 0.013
negative regulation of transport GO:0051051 176 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
brain morphogenesis GO:0048854 1 0.013
response to tumor necrosis factor GO:0034612 76 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
regulation of kinase activity GO:0043549 314 0.013
mitotic cell cycle checkpoint GO:0007093 68 0.013
cellular response to lipopolysaccharide GO:0071222 57 0.013
regulation of chromatin organization GO:1902275 56 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
regulation of intracellular transport GO:0032386 195 0.013
regulation of dephosphorylation GO:0035303 96 0.013
positive regulation of response to external stimulus GO:0032103 88 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
positive regulation of rab gtpase activity GO:0032851 39 0.013
positive regulation of cell migration GO:0030335 172 0.013
metal ion homeostasis GO:0055065 169 0.013
dna replication GO:0006260 116 0.013
regulation of histone modification GO:0031056 47 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
stem cell development GO:0048864 69 0.012
hippocampus development GO:0021766 1 0.012
transmission of nerve impulse GO:0019226 11 0.012
neurogenesis GO:0022008 169 0.012
regulation of translation GO:0006417 89 0.012
head development GO:0060322 108 0.012
taxis GO:0042330 157 0.012
atp metabolic process GO:0046034 176 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
response to ionizing radiation GO:0010212 65 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of cell cycle g1 s phase transition GO:1902806 42 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
amine metabolic process GO:0009308 44 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
leukocyte differentiation GO:0002521 98 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
forelimb morphogenesis GO:0035136 4 0.011
regulation of peptidase activity GO:0052547 180 0.011
sensory perception GO:0007600 103 0.011
positive regulation of protein localization to nucleus GO:1900182 48 0.011
reproductive system development GO:0061458 56 0.011
protein deubiquitination GO:0016579 79 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
lung alveolus development GO:0048286 4 0.011
lipid metabolic process GO:0006629 381 0.011
translation GO:0006412 132 0.011
secretory granule organization GO:0033363 2 0.011
embryonic forelimb morphogenesis GO:0035115 4 0.011
peptidyl lysine modification GO:0018205 144 0.011
retina homeostasis GO:0001895 42 0.011
protein dephosphorylation GO:0006470 81 0.011

ARFGEF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.826
Human
congenital nervous system abnormality DOID:2490 21 0.826
Human
cancer DOID:162 167 0.121
disease of cellular proliferation DOID:14566 174 0.121
central nervous system disease DOID:331 186 0.045
nervous system disease DOID:863 431 0.045
organ system cancer DOID:0050686 164 0.034
immune system disease DOID:2914 155 0.015
hematopoietic system disease DOID:74 100 0.013