Homo sapiens

159 known processes

ARFGEF2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

(Aliases: BIG2,dJ1164I10.1,PVNH2,FLJ23723)

ARFGEF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rho gtpase activity GO:0034259 4 0.998
Human
regulation of establishment of cell polarity GO:2000114 5 0.969
Human
regulation of actin filament polymerization GO:0030833 50 0.935
Human
protein glycosylation in golgi GO:0033578 3 0.883
Human
positive regulation of glycoprotein biosynthetic process GO:0010560 6 0.859
Human
actin filament polymerization GO:0030041 45 0.790
Human
negative regulation of nucleotide catabolic process GO:0030812 16 0.702
Human
gtp metabolic process GO:0046039 239 0.690
positive regulation of glycoprotein metabolic process GO:1903020 8 0.686
Human
regulation of actin filament length GO:0030832 56 0.635
Human
regulation of glycoprotein metabolic process GO:1903018 19 0.614
Human
regulation of wound healing GO:0061041 56 0.603
Human
gtp catabolic process GO:0006184 237 0.602
small gtpase mediated signal transduction GO:0007264 78 0.599
regulation of actin filament based process GO:0032970 141 0.592
Human
negative regulation of ras gtpase activity GO:0034261 6 0.591
Human
regulation of establishment or maintenance of cell polarity GO:0032878 7 0.579
Human
golgi vesicle transport GO:0048193 80 0.578
glycoprotein biosynthetic process GO:0009101 91 0.574
Human
regulation of protein polymerization GO:0032271 63 0.569
Human
rho protein signal transduction GO:0007266 26 0.567
actin filament based process GO:0030029 224 0.554
Human
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.554
regulation of response to wounding GO:1903034 101 0.551
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.528
Human
macromolecule glycosylation GO:0043413 63 0.524
Human
vesicle mediated transport GO:0016192 371 0.516
ras protein signal transduction GO:0007265 73 0.497
regulation of gtp catabolic process GO:0033124 180 0.495
guanosine containing compound metabolic process GO:1901068 244 0.480
negative regulation of actin filament polymerization GO:0030837 10 0.470
Human
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.440
Human
cellular protein complex assembly GO:0043623 188 0.431
Human
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.429
glycosyl compound catabolic process GO:1901658 413 0.428
post golgi vesicle mediated transport GO:0006892 36 0.417
purine nucleoside triphosphate metabolic process GO:0009144 412 0.402
purine ribonucleotide catabolic process GO:0009154 404 0.400
positive regulation of gtpase activity GO:0043547 166 0.398
glycosylation GO:0070085 71 0.391
Human
nucleoside phosphate catabolic process GO:1901292 412 0.390
guanosine containing compound catabolic process GO:1901069 239 0.385
regulation of carbohydrate metabolic process GO:0006109 54 0.382
Human
actin filament organization GO:0007015 128 0.381
Human
regulation of nucleotide catabolic process GO:0030811 205 0.374
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.364
purine nucleoside triphosphate catabolic process GO:0009146 392 0.347
negative regulation of protein polymerization GO:0032272 16 0.334
Human
tumor necrosis factor production GO:0032640 43 0.334
regulation of small gtpase mediated signal transduction GO:0051056 156 0.334
Human
regulation of protein glycosylation GO:0060049 6 0.328
Human
response to wounding GO:0009611 168 0.327
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.326
positive regulation of carbohydrate metabolic process GO:0045913 21 0.321
Human
regulation of tumor necrosis factor production GO:0032680 43 0.321
regulation of cytokine production GO:0001817 232 0.315
regulation of purine nucleotide metabolic process GO:1900542 264 0.314
regulation of cytoskeleton organization GO:0051493 177 0.310
Human
positive regulation of catabolic process GO:0009896 310 0.303
post embryonic development GO:0009791 2 0.301
cellular carbohydrate metabolic process GO:0044262 84 0.300
Human
endomembrane system organization GO:0010256 196 0.300
receptor metabolic process GO:0043112 81 0.297
membrane organization GO:0061024 292 0.297
ribonucleoside catabolic process GO:0042454 406 0.296
purine ribonucleoside catabolic process GO:0046130 398 0.293
ribonucleoside triphosphate catabolic process GO:0009203 391 0.287
positive regulation of response to wounding GO:1903036 28 0.286
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.285
nucleotide catabolic process GO:0009166 408 0.283
positive regulation of tumor necrosis factor production GO:0032760 21 0.280
single organism carbohydrate metabolic process GO:0044723 193 0.279
Human
regulation of cellular component size GO:0032535 82 0.278
Human
regulation of gtpase activity GO:0043087 180 0.277
endosome organization GO:0007032 20 0.271
positive regulation of nucleotide catabolic process GO:0030813 185 0.271
ribonucleotide catabolic process GO:0009261 405 0.270
cellular macromolecular complex assembly GO:0034622 324 0.267
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.256
nucleoside triphosphate catabolic process GO:0009143 394 0.246
regulation of nucleoside metabolic process GO:0009118 209 0.245
nucleoside catabolic process GO:0009164 408 0.245
negative regulation of cytoskeleton organization GO:0051494 45 0.241
Human
purine containing compound catabolic process GO:0072523 411 0.239
negative regulation of phosphorus metabolic process GO:0010563 267 0.238
Human
negative regulation of cellular component organization GO:0051129 235 0.227
Human
organophosphate catabolic process GO:0046434 430 0.222
negative regulation of catabolic process GO:0009895 104 0.221
Human
regulation of rho gtpase activity GO:0032319 66 0.219
Human
negative regulation of catalytic activity GO:0043086 335 0.219
Human
positive regulation of cytokine production GO:0001819 167 0.219
negative regulation of hydrolase activity GO:0051346 182 0.219
Human
negative regulation of cellular catabolic process GO:0031330 83 0.215
Human
carbohydrate metabolic process GO:0005975 207 0.213
Human
cytokine production GO:0001816 247 0.206
positive regulation of cellular catabolic process GO:0031331 284 0.202
actin cytoskeleton organization GO:0030036 207 0.199
Human
regulation of anatomical structure size GO:0090066 101 0.196
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.192
positive regulation of hydrolase activity GO:0051345 331 0.188
negative regulation of nucleotide metabolic process GO:0045980 29 0.186
Human
regulation of ras protein signal transduction GO:0046578 155 0.176
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.174
Human
negative regulation of organelle organization GO:0010639 126 0.166
Human
regulation of cellular component biogenesis GO:0044087 281 0.165
Human
regulation of nucleotide metabolic process GO:0006140 269 0.157
regulation of ras gtpase activity GO:0032318 128 0.142
Human
regulation of rho protein signal transduction GO:0035023 79 0.137
Human
purine nucleoside catabolic process GO:0006152 398 0.135
regulation of protein complex assembly GO:0043254 147 0.132
Human
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.115
Human
regulation of glycoprotein biosynthetic process GO:0010559 14 0.115
Human
cytoplasmic transport GO:0016482 379 0.112
regulation of cell differentiation GO:0045595 393 0.110
golgi to plasma membrane transport GO:0006893 21 0.104
negative regulation of gtpase activity GO:0034260 11 0.100
Human
endocytosis GO:0006897 159 0.094
phagocytosis engulfment GO:0006911 7 0.089
positive regulation of cellular component organization GO:0051130 376 0.084
apoptotic cell clearance GO:0043277 12 0.083
negative regulation of protein complex assembly GO:0031333 43 0.081
Human
anterior posterior axis specification GO:0009948 2 0.079
metal ion transport GO:0030001 272 0.076
establishment of cell polarity GO:0030010 22 0.074
Human
protein modification by small protein conjugation GO:0032446 342 0.074
locomotory behavior GO:0007626 1 0.073
positive regulation of phosphorylation GO:0042327 394 0.065
proteasomal protein catabolic process GO:0010498 176 0.064
ion transmembrane transport GO:0034220 338 0.063
receptor mediated endocytosis GO:0006898 84 0.063
cation transport GO:0006812 331 0.060
determination of adult lifespan GO:0008340 2 0.057
regulation of kinase activity GO:0043549 314 0.057
regulation of ion transport GO:0043269 189 0.057
phagocytosis GO:0006909 42 0.056
inorganic ion transmembrane transport GO:0098660 231 0.054
protein autophosphorylation GO:0046777 123 0.053
system process GO:0003008 349 0.053
female gamete generation GO:0007292 2 0.053
spermatid differentiation GO:0048515 4 0.052
mitochondrion organization GO:0007005 156 0.052
calcium ion homeostasis GO:0055074 122 0.051
regulation of transferase activity GO:0051338 355 0.051
spermatid development GO:0007286 4 0.051
metal ion homeostasis GO:0055065 169 0.050
protein catabolic process GO:0030163 325 0.049
establishment or maintenance of cell polarity GO:0007163 31 0.048
Human
oocyte development GO:0048599 1 0.048
cellular protein catabolic process GO:0044257 261 0.047
oxidation reduction process GO:0055114 396 0.044
positive regulation of mapk cascade GO:0043410 190 0.044
transmembrane transport GO:0055085 399 0.044
single organism membrane organization GO:0044802 268 0.044
cation homeostasis GO:0055080 189 0.042
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
cellular divalent inorganic cation homeostasis GO:0072503 128 0.041
cellular macromolecule catabolic process GO:0044265 380 0.040
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.040
anterior posterior axis specification embryo GO:0008595 2 0.039
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.039
regulation of axon guidance GO:1902667 3 0.039
oogenesis GO:0048477 2 0.038
endosomal transport GO:0016197 129 0.038
positive regulation of transport GO:0051050 336 0.038
embryo development GO:0009790 123 0.037
neural tube formation GO:0001841 3 0.037
protein localization to organelle GO:0033365 280 0.037
apoptotic signaling pathway GO:0097190 268 0.036
compound eye development GO:0048749 1 0.036
cellular cation homeostasis GO:0030003 163 0.036
engulfment of apoptotic cell GO:0043652 2 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
regulation of protein localization GO:0032880 296 0.034
oocyte differentiation GO:0009994 2 0.034
cell growth GO:0016049 160 0.034
embryonic forelimb morphogenesis GO:0035115 4 0.033
ion homeostasis GO:0050801 230 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
protein ubiquitination GO:0016567 314 0.031
regulation of response to external stimulus GO:0032101 222 0.031
tube morphogenesis GO:0035239 95 0.031
immune response GO:0006955 307 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
divalent inorganic cation homeostasis GO:0072507 136 0.030
memory GO:0007613 3 0.030
hindbrain development GO:0030902 3 0.030
regulation of proteolysis GO:0030162 293 0.029
protein processing GO:0016485 226 0.029
tripartite regional subdivision GO:0007351 2 0.029
cellular lipid metabolic process GO:0044255 303 0.029
regulation of map kinase activity GO:0043405 108 0.028
axon cargo transport GO:0008088 2 0.028
glycerolipid metabolic process GO:0046486 107 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.027
regulation of protein kinase activity GO:0045859 289 0.027
neuromuscular junction development GO:0007528 3 0.027
mapk cascade GO:0000165 288 0.026
meiosis i GO:0007127 4 0.026
hematopoietic or lymphoid organ development GO:0048534 186 0.026
organ morphogenesis GO:0009887 147 0.025
segmentation GO:0035282 4 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
immune system development GO:0002520 195 0.025
protein oligomerization GO:0051259 173 0.024
positive regulation of organelle organization GO:0010638 195 0.024
photoreceptor cell differentiation GO:0046530 2 0.024
covalent chromatin modification GO:0016569 254 0.024
cellular calcium ion homeostasis GO:0006874 117 0.024
cellular metal ion homeostasis GO:0006875 146 0.024
regulation of cell cycle process GO:0010564 266 0.024
neurological system process GO:0050877 163 0.024
regulation of axon extension involved in axon guidance GO:0048841 2 0.023
canonical wnt signaling pathway GO:0060070 116 0.023
regulation of cellular component movement GO:0051270 334 0.022
glycoprotein metabolic process GO:0009100 110 0.022
Human
negative regulation of protein modification process GO:0031400 200 0.022
maintenance of location GO:0051235 112 0.022
nucleotide biosynthetic process GO:0009165 109 0.022
regulation of locomotion GO:0040012 329 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
cellular ion homeostasis GO:0006873 168 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
nucleoside phosphate biosynthetic process GO:1901293 109 0.022
blastoderm segmentation GO:0007350 2 0.022
cellular ketone metabolic process GO:0042180 80 0.021
nucleus localization GO:0051647 1 0.021
regulation of metal ion transport GO:0010959 120 0.021
response to disaccharide GO:0034285 1 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
regulation of mapk cascade GO:0043408 262 0.021
multicellular organismal aging GO:0010259 3 0.021
cellular chemical homeostasis GO:0055082 180 0.021
lipid metabolic process GO:0006629 381 0.021
cellular component morphogenesis GO:0032989 314 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.020
reproduction GO:0000003 63 0.020
cell division GO:0051301 168 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
ameboidal type cell migration GO:0001667 135 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
cellular glucan metabolic process GO:0006073 22 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
regulation of calcium ion transport GO:0051924 79 0.020
cellular response to histamine GO:0071420 3 0.020
single organism reproductive process GO:0044702 98 0.020
sequestering of metal ion GO:0051238 24 0.019
regulation of protein ubiquitination GO:0031396 95 0.019
cerebellum development GO:0021549 2 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
nervous system development GO:0007399 293 0.019
erk1 and erk2 cascade GO:0070371 104 0.019
regulation of ossification GO:0030278 58 0.019
protein maturation GO:0051604 233 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
embryonic morphogenesis GO:0048598 85 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
lung alveolus development GO:0048286 4 0.019
negative regulation of protein metabolic process GO:0051248 391 0.018
regulation of cell motility GO:2000145 299 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
positive regulation of immune system process GO:0002684 283 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
myosin filament assembly GO:0031034 2 0.017
regulation of membrane potential GO:0042391 95 0.017
sequestering of calcium ion GO:0051208 17 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
intracellular mrna localization GO:0008298 1 0.017
embryonic viscerocranium morphogenesis GO:0048703 1 0.017
organelle localization GO:0051640 84 0.017
lipid modification GO:0030258 84 0.017
cell cycle phase transition GO:0044770 173 0.017
regulation of homeostatic process GO:0032844 121 0.017
dephosphorylation GO:0016311 209 0.016
regulation of cellular response to growth factor stimulus GO:0090287 76 0.016
developmental growth GO:0048589 48 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
ribose phosphate biosynthetic process GO:0046390 82 0.016
regulation of canonical wnt signaling pathway GO:0060828 88 0.016
response to organonitrogen compound GO:0010243 156 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
regulation of cell growth GO:0001558 135 0.016
cellular amine metabolic process GO:0044106 41 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.016
cellular amide metabolic process GO:0043603 69 0.016
rna interference GO:0016246 4 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
immune effector process GO:0002252 159 0.015
calcium ion transport GO:0006816 147 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
regulation of epithelial cell migration GO:0010632 93 0.015
innate immune response GO:0045087 178 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
chemical homeostasis GO:0048878 306 0.015
metencephalon development GO:0022037 2 0.015
biological adhesion GO:0022610 331 0.015
circadian behavior GO:0048512 2 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
embryo development ending in birth or egg hatching GO:0009792 34 0.015
skeletal system morphogenesis GO:0048705 24 0.015
protein deubiquitination GO:0016579 79 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
nuclear transport GO:0051169 179 0.015
amine metabolic process GO:0009308 44 0.015
regulation of cell activation GO:0050865 125 0.014
response to biotic stimulus GO:0009607 276 0.014
rhythmic behavior GO:0007622 2 0.014
plasma membrane organization GO:0007009 115 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
ossification GO:0001503 121 0.014
multicellular organismal reproductive process GO:0048609 40 0.014
response to oxygen containing compound GO:1901700 369 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
associative learning GO:0008306 1 0.014
response to nitrogen compound GO:1901698 184 0.014
organelle assembly GO:0070925 176 0.014
secretion GO:0046903 254 0.014
Rat
embryonic epithelial tube formation GO:0001838 4 0.014
positive regulation of cell size GO:0045793 3 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
response to radiation GO:0009314 151 0.014
lysosomal transport GO:0007041 33 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
positive regulation of transmembrane transport GO:0034764 41 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
nuclear migration GO:0007097 1 0.014
hemopoiesis GO:0030097 180 0.014
mitotic cell cycle phase transition GO:0044772 162 0.013
regulation of peptidase activity GO:0052547 180 0.013
secretion by cell GO:0032940 226 0.013
Rat
regulation of nucleotide biosynthetic process GO:0030808 50 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
protein localization to membrane GO:0072657 160 0.013
chromatin modification GO:0016568 298 0.013
establishment of protein localization to plasma membrane GO:0090002 68 0.013
regulation of cellular response to stress GO:0080135 244 0.013
single organism cellular localization GO:1902580 332 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
positive regulation of ion transport GO:0043270 87 0.013
methylation GO:0032259 106 0.013
cellular homeostasis GO:0019725 196 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
defense response GO:0006952 315 0.013
cell morphogenesis GO:0000902 296 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
cardiovascular system development GO:0072358 262 0.013
regulation of cell migration GO:0030334 289 0.013
lipid biosynthetic process GO:0008610 177 0.013
limbic system development GO:0021761 3 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of protein maturation GO:1903317 150 0.012
protein secretion GO:0009306 98 0.012
forelimb morphogenesis GO:0035136 4 0.012
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.012
behavioral response to ethanol GO:0048149 2 0.012
regulation of transmembrane transport GO:0034762 139 0.012
dna recombination GO:0006310 77 0.012
primary neural tube formation GO:0014020 3 0.012
protein homooligomerization GO:0051260 100 0.012
positive regulation of cell cycle GO:0045787 140 0.012
microtubule based process GO:0007017 210 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
peptidyl serine modification GO:0018209 106 0.012
divalent metal ion transport GO:0070838 152 0.012
epithelial cell proliferation GO:0050673 128 0.012
endosome to lysosome transport GO:0008333 21 0.012
regulation of neuron projection development GO:0010975 57 0.012
melanin metabolic process GO:0006582 1 0.012
protein acylation GO:0043543 138 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
neural tube closure GO:0001843 3 0.012
protein glycosylation GO:0006486 62 0.012
Human
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
sensory perception GO:0007600 103 0.012
response to sucrose GO:0009744 1 0.012
neuron development GO:0048666 113 0.012
negative regulation of cell death GO:0060548 345 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
anion transmembrane transport GO:0098656 76 0.011
cation transmembrane transport GO:0098655 238 0.011
cell projection organization GO:0030030 252 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
regulation of binding GO:0051098 111 0.011
regulation of sequestering of calcium ion GO:0051282 41 0.011
blastocyst development GO:0001824 3 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
dna replication GO:0006260 116 0.011
negative regulation of protein maturation GO:1903318 142 0.011
mitochondrion distribution GO:0048311 3 0.011
response to growth factor GO:0070848 205 0.011
positive regulation of ossification GO:0045778 32 0.011
regulation of intracellular transport GO:0032386 195 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
chemotaxis GO:0006935 157 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
actin mediated cell contraction GO:0070252 12 0.011
glycerophospholipid metabolic process GO:0006650 84 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
embryonic camera type eye morphogenesis GO:0048596 2 0.011
divalent inorganic cation transport GO:0072511 158 0.011
membrane invagination GO:0010324 10 0.011
cellular lipid catabolic process GO:0044242 65 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
wnt signaling pathway GO:0016055 156 0.011
cellular response to ammonium ion GO:0071242 4 0.011
digestive tract morphogenesis GO:0048546 56 0.011
brain development GO:0007420 97 0.011
alcohol metabolic process GO:0006066 114 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
lipid localization GO:0010876 106 0.011
regulation of defense response GO:0031347 154 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.011
actin filament based movement GO:0030048 17 0.010
taxis GO:0042330 157 0.010
jnk cascade GO:0007254 80 0.010
positive regulation of adenylate cyclase activity GO:0045762 12 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
mitotic cell cycle GO:0000278 326 0.010
actin polymerization or depolymerization GO:0008154 56 0.010
Human
regulation of dephosphorylation GO:0035303 96 0.010
response to abiotic stimulus GO:0009628 336 0.010
embryonic digestive tract morphogenesis GO:0048557 2 0.010
regulation of protein catabolic process GO:0042176 155 0.010
positive regulation of wnt signaling pathway GO:0030177 54 0.010
cell type specific apoptotic process GO:0097285 125 0.010
response to hormone GO:0009725 175 0.010
response to tumor necrosis factor GO:0034612 76 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
gastrulation with mouth forming second GO:0001702 1 0.010
regulation of establishment of protein localization GO:0070201 242 0.010
cell substrate adhesion GO:0031589 132 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
negative regulation of proteolysis GO:0045861 132 0.010

ARFGEF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.043
disease of cellular proliferation DOID:14566 174 0.043
bone development disease DOID:0080006 55 0.034
bone disease DOID:0080001 88 0.034
musculoskeletal system disease DOID:17 223 0.034
connective tissue disease DOID:65 109 0.034
organ system cancer DOID:0050686 164 0.028
immune system disease DOID:2914 155 0.027
endocrine gland cancer DOID:170 26 0.022
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
disease of metabolism DOID:0014667 295 0.014
hematopoietic system disease DOID:74 100 0.014
neurodegenerative disease DOID:1289 102 0.012
sensory system disease DOID:0050155 203 0.012
auditory system disease DOID:2742 53 0.012
physical disorder DOID:0080015 41 0.003
congenital nervous system abnormality DOID:2490 21 0.003