Homo sapiens

40 known processes

KARS

lysyl-tRNA synthetase

(Aliases: KARS2,CMTRIB,KIAA0070,KRS)

KARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.995
Worm
translation GO:0006412 132 0.890
trna aminoacylation for protein translation GO:0006418 8 0.849
trna aminoacylation GO:0043039 12 0.842
trna metabolic process GO:0006399 35 0.672
amino acid activation GO:0043038 12 0.592
embryo development GO:0009790 123 0.476
Worm
regulation of translation GO:0006417 89 0.356
cellular amino acid metabolic process GO:0006520 116 0.343
nuclear transport GO:0051169 179 0.317
cell cell signaling GO:0007267 155 0.307
vesicle mediated transport GO:0016192 371 0.292
embryo development ending in birth or egg hatching GO:0009792 34 0.269
Worm
endocytosis GO:0006897 159 0.256
ncrna processing GO:0034470 83 0.246
defense response GO:0006952 315 0.233
receptor mediated endocytosis GO:0006898 84 0.220
behavior GO:0007610 112 0.188
reproduction GO:0000003 63 0.151
Worm
rna transport GO:0050658 39 0.150
positive regulation of catabolic process GO:0009896 310 0.136
multicellular organismal aging GO:0010259 3 0.126
modification dependent macromolecule catabolic process GO:0043632 212 0.125
protein folding GO:0006457 38 0.122
cytoplasmic transport GO:0016482 379 0.122
positive regulation of cellular catabolic process GO:0031331 284 0.115
regulation of protein transport GO:0051223 213 0.111
innate immune response GO:0045087 178 0.104
nitrogen compound transport GO:0071705 191 0.099
nucleobase containing compound transport GO:0015931 51 0.099
nucleic acid transport GO:0050657 39 0.093
positive regulation of transport GO:0051050 336 0.091
negative regulation of multicellular organismal process GO:0051241 317 0.090
immune response GO:0006955 307 0.090
cellular macromolecule catabolic process GO:0044265 380 0.087
intracellular protein transport GO:0006886 270 0.087
regulation of intracellular protein transport GO:0033157 123 0.079
cellular protein catabolic process GO:0044257 261 0.073
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.071
positive regulation of nucleotide metabolic process GO:0045981 230 0.070
mitotic cell cycle GO:0000278 326 0.070
oogenesis GO:0048477 2 0.070
regulation of intracellular transport GO:0032386 195 0.066
negative regulation of protein metabolic process GO:0051248 391 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.056
posttranscriptional regulation of gene expression GO:0010608 213 0.055
rrna processing GO:0006364 35 0.054
rna phosphodiester bond hydrolysis GO:0090501 35 0.054
mitotic cell cycle process GO:1903047 286 0.053
anion transport GO:0006820 161 0.051
cellular protein complex assembly GO:0043623 188 0.049
system process GO:0003008 349 0.049
establishment of protein localization to organelle GO:0072594 172 0.048
action potential GO:0001508 34 0.048
ncrna metabolic process GO:0034660 108 0.046
ribonucleoprotein complex biogenesis GO:0022613 116 0.044
development of primary sexual characteristics GO:0045137 35 0.044
negative regulation of cell proliferation GO:0008285 228 0.044
sperm egg recognition GO:0035036 3 0.043
regulation of protein localization GO:0032880 296 0.041
reproductive structure development GO:0048608 55 0.041
ras protein signal transduction GO:0007265 73 0.039
reproductive system development GO:0061458 56 0.037
protein modification by small protein conjugation GO:0032446 342 0.037
lung epithelial cell differentiation GO:0060487 1 0.035
transmembrane transport GO:0055085 399 0.035
organelle assembly GO:0070925 176 0.034
cell development GO:0048468 328 0.034
response to hormone GO:0009725 175 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
mitochondrion organization GO:0007005 156 0.031
response to abiotic stimulus GO:0009628 336 0.031
nucleocytoplasmic transport GO:0006913 176 0.029
protein localization to nucleus GO:0034504 136 0.028
growth GO:0040007 202 0.028
Worm
single fertilization GO:0007338 11 0.028
mitotic nuclear division GO:0007067 119 0.027
rna localization GO:0006403 41 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
reproductive process GO:0022414 106 0.027
protein catabolic process GO:0030163 325 0.026
regulation of nucleoside metabolic process GO:0009118 209 0.026
binding of sperm to zona pellucida GO:0007339 3 0.026
multi organism cellular process GO:0044764 156 0.026
ribonucleoprotein complex assembly GO:0022618 78 0.026
protein targeting to nucleus GO:0044744 104 0.025
nucleus organization GO:0006997 28 0.025
gonad development GO:0008406 34 0.025
multicellular organismal reproductive process GO:0048609 40 0.025
regulation of cellular component biogenesis GO:0044087 281 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
epithelium development GO:0060429 227 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
rna splicing GO:0008380 131 0.023
female gamete generation GO:0007292 2 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
negative regulation of developmental process GO:0051093 247 0.023
multicellular organism reproduction GO:0032504 42 0.023
rrna modification GO:0000154 2 0.022
ribose phosphate biosynthetic process GO:0046390 82 0.022
response to cytokine GO:0034097 232 0.022
determination of adult lifespan GO:0008340 2 0.022
hemopoiesis GO:0030097 180 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
regulation of establishment of protein localization GO:0070201 242 0.021
regulation of nucleocytoplasmic transport GO:0046822 98 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
spermatid differentiation GO:0048515 4 0.021
protein import into nucleus GO:0006606 104 0.021
purine containing compound catabolic process GO:0072523 411 0.021
adult locomotory behavior GO:0008344 1 0.020
synaptic transmission GO:0007268 61 0.020
developmental growth GO:0048589 48 0.019
Worm
regulation of nucleotide metabolic process GO:0006140 269 0.019
regulation of cellular response to stress GO:0080135 244 0.019
positive regulation of protein transport GO:0051222 135 0.019
epithelial cell differentiation GO:0030855 141 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
neuromuscular junction development GO:0007528 3 0.019
single organism nuclear import GO:1902593 104 0.019
oocyte differentiation GO:0009994 2 0.018
protein localization to organelle GO:0033365 280 0.018
response to oxygen containing compound GO:1901700 369 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
nucleotide catabolic process GO:0009166 408 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.017
cell cell recognition GO:0009988 4 0.017
protein import GO:0017038 130 0.017
positive regulation of intracellular protein transport GO:0090316 76 0.017
macromolecule methylation GO:0043414 97 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
cellular respiration GO:0045333 21 0.016
neurological system process GO:0050877 163 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
locomotory behavior GO:0007626 1 0.015
rna 3 end processing GO:0031123 35 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
negative regulation of apoptotic process GO:0043066 316 0.014
regulation of cell differentiation GO:0045595 393 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
immune system development GO:0002520 195 0.014
sex differentiation GO:0007548 45 0.014
regulation of cell cycle GO:0051726 393 0.014
secretion GO:0046903 254 0.014
regulation of growth GO:0040008 165 0.014
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
nuclear export GO:0051168 69 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.013
protein processing GO:0016485 226 0.013
organelle fission GO:0048285 149 0.013
regulation of protein complex assembly GO:0043254 147 0.013
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.013
regulation of membrane potential GO:0042391 95 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
multicellular organismal signaling GO:0035637 34 0.013
oxidation reduction process GO:0055114 396 0.013
biological adhesion GO:0022610 331 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
alpha amino acid biosynthetic process GO:1901607 23 0.012
establishment of rna localization GO:0051236 39 0.012
single organism reproductive process GO:0044702 98 0.012
positive regulation of cytoplasmic transport GO:1903651 82 0.012
protein maturation GO:0051604 233 0.012
actin filament based process GO:0030029 224 0.012
regulation of cell migration GO:0030334 289 0.012
multi organism reproductive process GO:0044703 54 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
protein polymerization GO:0051258 71 0.012
regulation of immune response GO:0050776 201 0.012
developmental process involved in reproduction GO:0003006 66 0.012
activation of immune response GO:0002253 114 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.011
cellular homeostasis GO:0019725 196 0.011
phototransduction GO:0007602 3 0.011
secretion by cell GO:0032940 226 0.011
nuclear import GO:0051170 106 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regeneration GO:0031099 4 0.011
proteasomal protein catabolic process GO:0010498 176 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
aging GO:0007568 66 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
rrna metabolic process GO:0016072 40 0.010

KARS disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
neurodegenerative disease DOID:1289 102 0.012