Homo sapiens

341 known processes

IL12B

interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

(Aliases: NKSF,IL-12B,CLMF,NKSF2,CLMF2)

IL12B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nk t cell activation GO:0051133 4 1.000
nk t cell activation GO:0051132 4 0.997
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.989
positive regulation of cytokine production GO:0001819 167 0.978
regulation of interleukin 17 production GO:0032660 12 0.970
positive regulation of jak stat cascade GO:0046427 35 0.966
tyrosine phosphorylation of stat protein GO:0007260 33 0.959
positive regulation of lymphocyte proliferation GO:0050671 46 0.948
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.928
regulation of mononuclear cell proliferation GO:0032944 65 0.927
regulation of cellular amino acid metabolic process GO:0006521 6 0.927
lymphocyte mediated immunity GO:0002449 48 0.926
amine metabolic process GO:0009308 44 0.916
cytokine production GO:0001816 247 0.909
defense response to bacterium GO:0042742 63 0.908
positive regulation of alpha beta t cell proliferation GO:0046641 5 0.891
regulation of cellular ketone metabolic process GO:0010565 50 0.891
regulation of cytokine production GO:0001817 232 0.878
negative regulation of cytokine production GO:0001818 82 0.877
peptidyl tyrosine phosphorylation GO:0018108 170 0.864
natural killer cell activation GO:0030101 12 0.862
regulation of lymphocyte mediated immunity GO:0002706 33 0.851
adaptive immune response GO:0002250 49 0.838
lymphocyte proliferation GO:0046651 70 0.830
response to biotic stimulus GO:0009607 276 0.830
regulation of osteoclast differentiation GO:0045670 18 0.825
positive regulation of phosphorylation GO:0042327 394 0.804
response to virus GO:0009615 126 0.802
regulation of chemotaxis GO:0050920 74 0.797
regulation of lymphocyte activation GO:0051249 103 0.796
response to bacterium GO:0009617 144 0.795
regulation of t cell activation GO:0050863 77 0.795
cellular ketone metabolic process GO:0042180 80 0.793
positive regulation of immune response GO:0050778 159 0.791
positive regulation of interferon gamma production GO:0032729 26 0.791
defense response GO:0006952 315 0.789
positive regulation of cell proliferation GO:0008284 301 0.787
interferon gamma production GO:0032609 39 0.785
response to other organism GO:0051707 261 0.785
leukocyte activation GO:0045321 164 0.774
regulation of jak stat cascade GO:0046425 44 0.760
negative regulation of multicellular organismal process GO:0051241 317 0.760
jak stat cascade GO:0007259 46 0.759
t cell activation GO:0042110 99 0.746
cell activation GO:0001775 213 0.735
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.718
osteoclast differentiation GO:0030316 21 0.716
positive regulation of activation of jak2 kinase activity GO:0010535 4 0.713
positive regulation of activation of janus kinase activity GO:0010536 5 0.713
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.704
positive regulation of adaptive immune response GO:0002821 21 0.697
immune effector process GO:0002252 159 0.685
response to external biotic stimulus GO:0043207 261 0.684
regulation of cell activation GO:0050865 125 0.674
lymphocyte activation GO:0046649 133 0.669
regulation of natural killer cell activation GO:0032814 9 0.659
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.658
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.657
regulation of immune response GO:0050776 201 0.652
regulation of neutrophil chemotaxis GO:0090022 10 0.652
positive regulation of immune system process GO:0002684 283 0.641
regulation of t cell mediated immunity GO:0002709 18 0.636
regulation of leukocyte proliferation GO:0070663 67 0.632
positive regulation of mononuclear cell proliferation GO:0032946 47 0.631
positive regulation of natural killer cell proliferation GO:0032819 3 0.625
nk t cell proliferation GO:0001866 3 0.621
regulation of defense response GO:0031347 154 0.614
regulation of leukocyte migration GO:0002685 63 0.609
regulation of myeloid leukocyte differentiation GO:0002761 39 0.608
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.604
negative regulation of interleukin 10 production GO:0032693 7 0.602
positive regulation of t helper cell differentiation GO:0045624 2 0.602
regulation of leukocyte differentiation GO:1902105 61 0.591
positive regulation of protein phosphorylation GO:0001934 313 0.580
positive regulation of leukocyte mediated immunity GO:0002705 24 0.572
regulation of leukocyte chemotaxis GO:0002688 46 0.567
positive regulation of cell killing GO:0031343 19 0.567
cellular amine metabolic process GO:0044106 41 0.565
regulation of interferon gamma production GO:0032649 36 0.561
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.559
immune response GO:0006955 307 0.551
regulation of myeloid cell differentiation GO:0045637 81 0.551
positive regulation of neutrophil migration GO:1902624 7 0.549
leukocyte mediated cytotoxicity GO:0001909 27 0.544
regulation of cellular amine metabolic process GO:0033238 11 0.543
positive regulation of behavior GO:0048520 60 0.542
regulation of natural killer cell proliferation GO:0032817 4 0.536
regulation of t cell proliferation GO:0042129 42 0.536
leukocyte migration GO:0050900 107 0.533
alpha beta t cell proliferation GO:0046633 5 0.529
immune system development GO:0002520 195 0.524
positive regulation of chemotaxis GO:0050921 57 0.516
g protein coupled receptor signaling pathway GO:0007186 207 0.515
cell chemotaxis GO:0060326 112 0.509
positive regulation of cellular amine metabolic process GO:0033240 7 0.509
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.508
regulation of neutrophil migration GO:1902622 10 0.507
positive regulation of leukocyte proliferation GO:0070665 48 0.498
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.493
positive regulation of leukocyte chemotaxis GO:0002690 38 0.490
positive regulation of neutrophil chemotaxis GO:0090023 7 0.486
granulocyte migration GO:0097530 40 0.482
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 5 0.476
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.471
leukocyte differentiation GO:0002521 98 0.470
positive regulation of leukocyte migration GO:0002687 46 0.462
defense response to virus GO:0051607 71 0.456
granulocyte chemotaxis GO:0071621 37 0.452
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.447
hematopoietic or lymphoid organ development GO:0048534 186 0.434
regulation of activation of janus kinase activity GO:0010533 6 0.428
regulation of leukocyte activation GO:0002694 115 0.420
myeloid cell differentiation GO:0030099 117 0.415
activation of janus kinase activity GO:0042976 7 0.412
regulation of activation of jak2 kinase activity GO:0010534 5 0.412
regulation of response to external stimulus GO:0032101 222 0.410
neutrophil migration GO:1990266 25 0.402
regulation of defense response to virus by host GO:0050691 22 0.400
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.395
positive regulation of immune effector process GO:0002699 40 0.393
t cell mediated immunity GO:0002456 25 0.390
regulation of tumor necrosis factor production GO:0032680 43 0.389
leukocyte mediated immunity GO:0002443 59 0.382
positive regulation of developmental process GO:0051094 314 0.375
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.370
leukocyte chemotaxis GO:0030595 76 0.369
positive regulation of response to external stimulus GO:0032103 88 0.364
positive regulation of alpha beta t cell activation GO:0046635 10 0.364
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.363
t cell mediated cytotoxicity GO:0001913 9 0.362
myeloid leukocyte migration GO:0097529 62 0.359
activation of protein kinase activity GO:0032147 90 0.358
regulation of immune effector process GO:0002697 91 0.357
positive regulation of myeloid cell differentiation GO:0045639 39 0.355
positive regulation of interleukin 17 production GO:0032740 8 0.351
regulation of smooth muscle cell proliferation GO:0048660 28 0.349
positive regulation of defense response to virus by host GO:0002230 14 0.347
t cell selection GO:0045058 4 0.334
regulation of protein kinase activity GO:0045859 289 0.332
positive regulation of t helper 1 type immune response GO:0002827 4 0.323
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.321
positive regulation of granulocyte chemotaxis GO:0071624 9 0.312
t cell proliferation GO:0042098 45 0.309
positive regulation of cell migration GO:0030335 172 0.309
positive regulation of kinase activity GO:0033674 204 0.307
regulation of behavior GO:0050795 82 0.303
positive regulation of interleukin 12 production GO:0032735 8 0.302
positive regulation of cellular component movement GO:0051272 181 0.300
regulation of response to biotic stimulus GO:0002831 55 0.287
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.286
regulation of cell migration GO:0030334 289 0.285
taxis GO:0042330 157 0.282
positive regulation of transferase activity GO:0051347 227 0.281
regulation of cellular component movement GO:0051270 334 0.279
mononuclear cell proliferation GO:0032943 71 0.276
activated t cell proliferation GO:0050798 13 0.273
regulation of lymphocyte proliferation GO:0050670 64 0.273
regulation of t cell mediated cytotoxicity GO:0001914 8 0.269
cell activation involved in immune response GO:0002263 30 0.268
regulation of cell motility GO:2000145 299 0.265
positive regulation of t cell mediated immunity GO:0002711 12 0.263
positive regulation of locomotion GO:0040017 186 0.259
positive regulation of cell motility GO:2000147 177 0.251
regulation of adaptive immune response GO:0002819 33 0.240
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.236
chemotaxis GO:0006935 157 0.235
regulation of t helper 1 type immune response GO:0002825 5 0.235
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.233
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.232
positive regulation of lymphocyte activation GO:0051251 73 0.231
innate immune response GO:0045087 178 0.229
granulocyte macrophage colony stimulating factor production GO:0032604 5 0.226
regulation of granulocyte chemotaxis GO:0071622 16 0.224
regulation of locomotion GO:0040012 329 0.218
response to lipid GO:0033993 206 0.217
cellular amino acid metabolic process GO:0006520 116 0.212
positive regulation of cell fate commitment GO:0010455 2 0.207
neutrophil chemotaxis GO:0030593 24 0.203
regulation of defense response to virus GO:0050688 33 0.197
alpha beta t cell differentiation involved in immune response GO:0002293 5 0.195
t cell differentiation GO:0030217 29 0.194
leukocyte activation involved in immune response GO:0002366 30 0.192
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.185
positive regulation of tumor necrosis factor production GO:0032760 21 0.183
secretion GO:0046903 254 0.183
positive regulation of activated t cell proliferation GO:0042104 11 0.181
defense response to other organism GO:0098542 129 0.181
alpha beta t cell activation GO:0046631 15 0.175
leukocyte proliferation GO:0070661 74 0.173
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.170
response to cytokine GO:0034097 232 0.166
positive regulation of transport GO:0051050 336 0.163
regulation of t helper cell differentiation GO:0045622 3 0.160
regulation of ion transport GO:0043269 189 0.155
regulation of alpha beta t cell activation GO:0046634 13 0.155
regulation of cell differentiation GO:0045595 393 0.154
memory t cell differentiation GO:0043379 2 0.153
interleukin 10 production GO:0032613 17 0.148
natural killer cell proliferation GO:0001787 4 0.144
response to organic cyclic compound GO:0014070 204 0.143
cation transport GO:0006812 331 0.142
response to lipopolysaccharide GO:0032496 70 0.138
negative regulation of cell proliferation GO:0008285 228 0.136
apoptotic signaling pathway GO:0097190 268 0.135
eosinophil activation involved in immune response GO:0002278 2 0.133
myeloid dendritic cell chemotaxis GO:0002408 3 0.127
regulation of interleukin 10 production GO:0032653 16 0.126
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.125
muscle cell proliferation GO:0033002 35 0.123
glial cell migration GO:0008347 4 0.122
regulation of leukocyte mediated immunity GO:0002703 38 0.119
alpha beta t cell differentiation GO:0046632 7 0.119
regulation of cell killing GO:0031341 22 0.118
cytokine mediated signaling pathway GO:0019221 109 0.113
activation of jak2 kinase activity GO:0042977 5 0.109
sensory perception of pain GO:0019233 4 0.106
cellular response to cytokine stimulus GO:0071345 181 0.105
biological adhesion GO:0022610 331 0.105
negative regulation of cell death GO:0060548 345 0.105
cellular ion homeostasis GO:0006873 168 0.105
negative regulation of t cell cytokine production GO:0002725 4 0.104
cd4 positive alpha beta t cell activation GO:0035710 6 0.103
response to oxygen containing compound GO:1901700 369 0.103
positive regulation of programmed cell death GO:0043068 249 0.102
transmembrane transport GO:0055085 399 0.102
regulation of interleukin 12 production GO:0032655 15 0.100
regulation of cell cycle GO:0051726 393 0.100
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.100
hemopoiesis GO:0030097 180 0.100
response to abiotic stimulus GO:0009628 336 0.098
chemical homeostasis GO:0048878 306 0.096
eosinophil mediated immunity GO:0002447 2 0.095
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.094
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.094
cell type specific apoptotic process GO:0097285 125 0.093
regulation of cell adhesion GO:0030155 166 0.092
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.092
positive regulation of leukocyte activation GO:0002696 80 0.091
calcium ion transport GO:0006816 147 0.091
peptidyl tyrosine modification GO:0018212 170 0.090
cellular response to endogenous stimulus GO:0071495 336 0.089
lipid metabolic process GO:0006629 381 0.085
neurological system process GO:0050877 163 0.085
positive regulation of mapk cascade GO:0043410 190 0.085
positive regulation of muscle cell apoptotic process GO:0010661 4 0.083
positive regulation of cell activation GO:0050867 81 0.083
regulation of granzyme a production GO:2000511 1 0.083
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.082
regulation of cd4 positive alpha beta t cell activation GO:2000514 5 0.080
negative regulation of interleukin 17 production GO:0032700 5 0.080
t cell lineage commitment GO:0002360 1 0.079
positive regulation of t cell activation GO:0050870 54 0.078
t cell differentiation involved in immune response GO:0002292 7 0.078
behavior GO:0007610 112 0.076
negative regulation of alpha beta t cell activation GO:0046636 3 0.076
ion homeostasis GO:0050801 230 0.075
regulation of secretion GO:0051046 194 0.074
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.074
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.073
mature natural killer cell chemotaxis GO:0035782 1 0.072
regulation of purine nucleotide metabolic process GO:1900542 264 0.072
sequestering of calcium ion GO:0051208 17 0.071
regulation of establishment of protein localization GO:0070201 242 0.070
divalent inorganic cation transport GO:0072511 158 0.068
defense response to gram negative bacterium GO:0050829 14 0.068
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.068
regulation of ion transmembrane transport GO:0034765 132 0.068
regulation of camp metabolic process GO:0030814 52 0.067
sequestering of metal ion GO:0051238 24 0.065
cytoplasmic transport GO:0016482 379 0.065
alpha beta t cell activation involved in immune response GO:0002287 5 0.064
negative regulation of natural killer cell chemotaxis GO:2000502 1 0.064
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.064
positive regulation of cellular component organization GO:0051130 376 0.063
regulation of system process GO:0044057 101 0.063
regulation of memory t cell differentiation GO:0043380 2 0.063
response to nitric oxide GO:0071731 4 0.063
regulation of viral process GO:0050792 103 0.062
regulation of multi organism process GO:0043900 157 0.061
regulation of protein localization GO:0032880 296 0.061
negative regulation of lymphocyte migration GO:2000402 4 0.060
protein localization to organelle GO:0033365 280 0.060
regulation of c c chemokine binding GO:2001263 1 0.059
positive regulation of hydrolase activity GO:0051345 331 0.059
negative regulation of programmed cell death GO:0043069 321 0.058
response to nitrogen compound GO:1901698 184 0.058
positive regulation of lymphocyte differentiation GO:0045621 13 0.058
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.057
positive regulation of nucleotide metabolic process GO:0045981 230 0.056
cellular lipid metabolic process GO:0044255 303 0.056
granzyme a production GO:0035746 1 0.056
lymphocyte activation involved in immune response GO:0002285 20 0.056
regulation of nucleotide metabolic process GO:0006140 269 0.056
divalent metal ion transport GO:0070838 152 0.056
cytosolic calcium ion homeostasis GO:0051480 89 0.056
metal ion transport GO:0030001 272 0.055
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.055
regulation of t helper 1 cell activation GO:2000517 1 0.055
cellular homeostasis GO:0019725 196 0.055
cellular metal ion homeostasis GO:0006875 146 0.054
regulation of t cell differentiation GO:0045580 19 0.054
sensory perception GO:0007600 103 0.054
nucleoside catabolic process GO:0009164 408 0.054
smooth muscle cell proliferation GO:0048659 28 0.054
viral process GO:0016032 146 0.053
regulation of metal ion transport GO:0010959 120 0.053
response to radiation GO:0009314 151 0.053
positive regulation of t cell mediated cytotoxicity GO:0001916 7 0.052
positive regulation of cytoplasmic transport GO:1903651 82 0.052
positive regulation of catabolic process GO:0009896 310 0.052
t cell activation involved in immune response GO:0002286 13 0.052
response to hormone GO:0009725 175 0.051
small gtpase mediated signal transduction GO:0007264 78 0.051
signal transduction by phosphorylation GO:0023014 297 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.050
regulation of secretion by cell GO:1903530 177 0.050
positive regulation of secretion GO:0051047 116 0.050
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 2 0.050
response to molecule of bacterial origin GO:0002237 82 0.049
cd8 positive alpha beta t cell activation GO:0036037 3 0.049
eosinophil degranulation GO:0043308 2 0.049
positive regulation of t cell differentiation GO:0045582 11 0.048
positive regulation of t cell migration GO:2000406 13 0.048
regulation of alpha beta t cell differentiation GO:0046637 5 0.048
extrinsic apoptotic signaling pathway GO:0097191 119 0.048
purine nucleoside catabolic process GO:0006152 398 0.048
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.047
cellular cation homeostasis GO:0030003 163 0.047
cellular chemical homeostasis GO:0055082 180 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.047
positive regulation of cellular catabolic process GO:0031331 284 0.047
cytokine secretion GO:0050663 64 0.046
negative regulation of cytokine production involved in immune response GO:0002719 13 0.046
regulation of sensory perception of pain GO:0051930 3 0.046
interleukin 17 production GO:0032620 12 0.046
glycosyl compound catabolic process GO:1901658 413 0.046
maintenance of location GO:0051235 112 0.046
organophosphate catabolic process GO:0046434 430 0.046
guanosine containing compound catabolic process GO:1901069 239 0.046
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 3 0.045
granzyme b production GO:0071613 1 0.045
vesicle mediated transport GO:0016192 371 0.045
positive regulation of ion transport GO:0043270 87 0.044
regulation of anatomical structure morphogenesis GO:0022603 286 0.044
inorganic ion transmembrane transport GO:0098660 231 0.044
protein secretion GO:0009306 98 0.044
reactive oxygen species biosynthetic process GO:1903409 4 0.043
ras protein signal transduction GO:0007265 73 0.043
post embryonic development GO:0009791 2 0.043
erk1 and erk2 cascade GO:0070371 104 0.042
nitrogen compound transport GO:0071705 191 0.042
positive regulation of intracellular transport GO:0032388 104 0.042
positive regulation of t cell proliferation GO:0042102 33 0.041
viral life cycle GO:0019058 132 0.041
regulation of nucleotide catabolic process GO:0030811 205 0.041
regulation of cellular component biogenesis GO:0044087 281 0.041
single organism cellular localization GO:1902580 332 0.041
ribonucleotide catabolic process GO:0009261 405 0.041
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
positive regulation of gtp catabolic process GO:0033126 166 0.041
gtp metabolic process GO:0046039 239 0.040
regulation of calcium ion transport GO:0051924 79 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
response to wounding GO:0009611 168 0.040
positive regulation of granzyme b production GO:0071663 1 0.040
secretion by cell GO:0032940 226 0.040
regulation of transmembrane transport GO:0034762 139 0.040
negative regulation of c c chemokine binding GO:2001264 1 0.040
regulation of protein transport GO:0051223 213 0.039
ion transmembrane transport GO:0034220 338 0.039
regulation of protein complex assembly GO:0043254 147 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.039
cellular response to oxygen containing compound GO:1901701 276 0.039
regulation of sensory perception GO:0051931 3 0.039
positive regulation of nucleoside metabolic process GO:0045979 186 0.039
cellular response to growth factor stimulus GO:0071363 197 0.038
positive regulation of apoptotic process GO:0043065 246 0.038
rho protein signal transduction GO:0007266 26 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
regulation of t cell migration GO:2000404 14 0.037
positive regulation of cell differentiation GO:0045597 211 0.037
peptide transport GO:0015833 74 0.037
cellular calcium ion homeostasis GO:0006874 117 0.037
i kappab kinase nf kappab signaling GO:0007249 166 0.037
guanosine containing compound metabolic process GO:1901068 244 0.037
positive regulation of t cell apoptotic process GO:0070234 4 0.036
cell cycle arrest GO:0007050 71 0.036
lymphocyte chemotaxis GO:0048247 17 0.036
regulation of lymphocyte migration GO:2000401 22 0.036
positive regulation of defense response GO:0031349 87 0.036
response to light stimulus GO:0009416 87 0.036
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.036
cellular response to organic cyclic compound GO:0071407 127 0.035
astrocyte cell migration GO:0043615 1 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.035
negative regulation of apoptotic process GO:0043066 316 0.035
system process GO:0003008 349 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
positive regulation of cell death GO:0010942 263 0.034
positive regulation of organelle organization GO:0010638 195 0.034
positive t cell selection GO:0043368 2 0.034
positive regulation of calcium ion transport GO:0051928 51 0.034
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.034
metal ion homeostasis GO:0055065 169 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.033
protein oligomerization GO:0051259 173 0.033
positive regulation of nucleotide catabolic process GO:0030813 185 0.033
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
regulation of sequestering of calcium ion GO:0051282 41 0.033
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.033
response to growth factor GO:0070848 205 0.033
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
positive regulation of lymphocyte migration GO:2000403 16 0.033
regulation of cellular response to stress GO:0080135 244 0.033
camp metabolic process GO:0046058 61 0.033
regulation of transferase activity GO:0051338 355 0.033
eosinophil activation GO:0043307 3 0.033
protein import into nucleus GO:0006606 104 0.032
positive regulation of protein transport GO:0051222 135 0.032
protein targeting GO:0006605 187 0.032
purine containing compound catabolic process GO:0072523 411 0.032
regulation of lymphocyte differentiation GO:0045619 22 0.032
cation homeostasis GO:0055080 189 0.032
nucleoside triphosphate metabolic process GO:0009141 422 0.032
myeloid leukocyte differentiation GO:0002573 60 0.032
establishment of lymphocyte polarity GO:0001767 2 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
lymphocyte migration GO:0072676 28 0.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.031
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
defense response to gram positive bacterium GO:0050830 29 0.031
cation transmembrane transport GO:0098655 238 0.031
nucleotide catabolic process GO:0009166 408 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.031
negative regulation of t helper 1 cell activation GO:2000518 1 0.031
mapk cascade GO:0000165 288 0.031
regulation of granzyme b production GO:0071661 1 0.031
positive regulation of gtpase activity GO:0043547 166 0.031
positive regulation of protein kinase activity GO:0045860 190 0.030
positive regulation of transmembrane transport GO:0034764 41 0.030
regulation of kinase activity GO:0043549 314 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
cellular divalent inorganic cation homeostasis GO:0072503 128 0.030
cellular macromolecular complex assembly GO:0034622 324 0.030
regulation of jnk cascade GO:0046328 73 0.029
regulation of mapk cascade GO:0043408 262 0.029
second messenger mediated signaling GO:0019932 78 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
reactive nitrogen species metabolic process GO:2001057 3 0.029
bone mineralization GO:0030282 34 0.029
t helper 1 cell activation GO:0035711 1 0.029
cell adhesion GO:0007155 325 0.029
establishment of t cell polarity GO:0001768 2 0.029
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 6 0.028
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.028
release of sequestered calcium ion into cytosol GO:0051209 41 0.028
divalent inorganic cation homeostasis GO:0072507 136 0.028
regulation of homeostatic process GO:0032844 121 0.027
associative learning GO:0008306 1 0.027
calcium ion homeostasis GO:0055074 122 0.027
regulation of cytoplasmic transport GO:1903649 149 0.027
intracellular protein transport GO:0006886 270 0.027
cellular response to lipid GO:0071396 127 0.027
nervous system development GO:0007399 293 0.027
cardiac muscle cell contraction GO:0086003 4 0.027
cellular response to tumor necrosis factor GO:0071356 63 0.027
locomotory behavior GO:0007626 1 0.027
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.027
t cell chemotaxis GO:0010818 10 0.027
multi organism cellular process GO:0044764 156 0.026
response to interferon gamma GO:0034341 39 0.026
regulation of gtpase activity GO:0043087 180 0.026
single organism nuclear import GO:1902593 104 0.026
regulation of intracellular transport GO:0032386 195 0.026
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 6 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
negative regulation of developmental process GO:0051093 247 0.026
ossification GO:0001503 121 0.026
negative regulation of transport GO:0051051 176 0.026
cell morphogenesis GO:0000902 296 0.026
determination of adult lifespan GO:0008340 2 0.026
positive regulation of protein complex assembly GO:0031334 86 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.026
positive regulation of secretion by cell GO:1903532 108 0.026
actin filament based process GO:0030029 224 0.026
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.026
negative regulation of immune system process GO:0002683 136 0.025
regulation of t cell chemotaxis GO:0010819 7 0.025
negative regulation of catalytic activity GO:0043086 335 0.025

IL12B disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030