Homo sapiens

51 known processes

BBS4

Bardet-Biedl syndrome 4

BBS4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 63 1.000
Zebrafish Mouse
intraciliary transport GO:0042073 7 0.999
cilium morphogenesis GO:0060271 75 0.995
Zebrafish Mouse
sensory perception of smell GO:0007608 2 0.932
Mouse
cilium organization GO:0044782 68 0.860
Zebrafish Mouse
cellular component assembly involved in morphogenesis GO:0010927 73 0.826
Zebrafish Mouse
cell projection assembly GO:0030031 126 0.650
Zebrafish Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.606
Zebrafish Mouse
microtubule anchoring at microtubule organizing center GO:0072393 1 0.526
pattern specification involved in kidney development GO:0061004 1 0.500
cell projection organization GO:0030030 252 0.487
Zebrafish Mouse
organelle assembly GO:0070925 176 0.473
Zebrafish Mouse
golgi vesicle transport GO:0048193 80 0.459
cell proliferation in forebrain GO:0021846 1 0.413
fat cell differentiation GO:0045444 32 0.390
Mouse
cell projection morphogenesis GO:0048858 129 0.388
Zebrafish Mouse
establishment of protein localization to plasma membrane GO:0090002 68 0.374
single organism cellular localization GO:1902580 332 0.373
Zebrafish
endomembrane system organization GO:0010256 196 0.369
single organism membrane organization GO:0044802 268 0.359
nervous system development GO:0007399 293 0.295
Zebrafish Mouse
membrane organization GO:0061024 292 0.284
intracellular protein transport GO:0006886 270 0.282
establishment of protein localization to membrane GO:0090150 121 0.266
renal system pattern specification GO:0072048 1 0.243
sensory perception of chemical stimulus GO:0007606 38 0.225
Mouse
regulation of metanephros size GO:0035566 1 0.222
post golgi vesicle mediated transport GO:0006892 36 0.222
protein localization to organelle GO:0033365 280 0.213
eye photoreceptor cell differentiation GO:0001754 2 0.198
Mouse
paramesonephric duct development GO:0061205 2 0.197
cytoplasmic transport GO:0016482 379 0.189
photoreceptor cell differentiation GO:0046530 2 0.175
Zebrafish Mouse
protein localization to plasma membrane GO:0072659 93 0.175
forebrain development GO:0030900 26 0.173
Mouse
vesicle mediated transport GO:0016192 371 0.161
cellular component morphogenesis GO:0032989 314 0.160
Zebrafish Mouse
negative regulation of kidney development GO:0090185 2 0.150
protein localization to membrane GO:0072657 160 0.136
protein localization to cytoskeleton GO:0044380 11 0.133
protein localization to microtubule cytoskeleton GO:0072698 10 0.131
cellular protein complex assembly GO:0043623 188 0.128
neuronal stem cell maintenance GO:0097150 5 0.126
microtubule based movement GO:0007018 32 0.109
Mouse
organ morphogenesis GO:0009887 147 0.108
Zebrafish Mouse
nucleus localization GO:0051647 1 0.104
plasma membrane organization GO:0007009 115 0.103
positive regulation of catabolic process GO:0009896 310 0.101
cell morphogenesis GO:0000902 296 0.092
Zebrafish Mouse
smoothened signaling pathway GO:0007224 14 0.089
golgi to plasma membrane protein transport GO:0043001 19 0.087
mesonephric tubule formation GO:0072172 1 0.084
maintenance of protein location GO:0045185 57 0.084
eye development GO:0001654 42 0.083
Mouse
centrosome organization GO:0051297 58 0.080
negative regulation of developmental process GO:0051093 247 0.080
maintenance of location in cell GO:0051651 62 0.079
cytoskeleton dependent intracellular transport GO:0030705 21 0.076
cellular response to external stimulus GO:0071496 111 0.075
urogenital system development GO:0001655 65 0.075
regulation of protein localization GO:0032880 296 0.075
head development GO:0060322 108 0.075
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.074
maintenance of protein location in cell GO:0032507 56 0.074
golgi to plasma membrane transport GO:0006893 21 0.073
regulation of thyroid hormone generation GO:2000609 2 0.072
positive regulation of intracellular protein transport GO:0090316 76 0.071
regulation of intracellular transport GO:0032386 195 0.070
positive regulation of protein transport GO:0051222 135 0.069
protein catabolic process GO:0030163 325 0.069
cellular macromolecule catabolic process GO:0044265 380 0.067
negative regulation of cell development GO:0010721 48 0.067
cellular amino acid metabolic process GO:0006520 116 0.065
microtubule based process GO:0007017 210 0.062
regulation of protein transport GO:0051223 213 0.062
cell part morphogenesis GO:0032990 137 0.060
Zebrafish Mouse
renal system development GO:0072001 63 0.060
tissue homeostasis GO:0001894 63 0.057
Mouse
regulation of intracellular protein transport GO:0033157 123 0.052
ribonucleoside catabolic process GO:0042454 406 0.052
nucleotide catabolic process GO:0009166 408 0.052
morphogenesis of embryonic epithelium GO:0016331 4 0.051
Mouse
cofactor metabolic process GO:0051186 87 0.050
cellular response to endogenous stimulus GO:0071495 336 0.049
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 186 0.049
neural retina development GO:0003407 8 0.047
camera type eye photoreceptor cell differentiation GO:0060219 1 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.047
renal tubule development GO:0061326 19 0.046
maintenance of location GO:0051235 112 0.045
purine containing compound catabolic process GO:0072523 411 0.045
positive regulation of hydrolase activity GO:0051345 331 0.045
multicellular organismal homeostasis GO:0048871 67 0.044
Mouse
tube development GO:0035295 125 0.043
Zebrafish Mouse
neural tube formation GO:0001841 3 0.042
Mouse
regulation of cell differentiation GO:0045595 393 0.040
microtubule cytoskeleton organization GO:0000226 176 0.040
negative regulation of cell differentiation GO:0045596 171 0.039
ribonucleoside monophosphate metabolic process GO:0009161 187 0.039
distal tubule development GO:0072017 4 0.039
atp metabolic process GO:0046034 176 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
positive regulation of transport GO:0051050 336 0.037
modification dependent macromolecule catabolic process GO:0043632 212 0.037
regulation of cell development GO:0060284 161 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
cell development GO:0048468 328 0.036
Zebrafish Mouse
specification of organ identity GO:0010092 3 0.035
neurogenesis GO:0022008 169 0.035
Zebrafish Mouse
cellular macromolecular complex assembly GO:0034622 324 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.034
organelle localization GO:0051640 84 0.034
Zebrafish
positive regulation of intracellular transport GO:0032388 104 0.034
post embryonic development GO:0009791 2 0.034
stem cell development GO:0048864 69 0.033
positive regulation of nucleotide catabolic process GO:0030813 185 0.033
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
embryonic camera type eye development GO:0031076 2 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
eye morphogenesis GO:0048592 16 0.032
Mouse
anatomical structure homeostasis GO:0060249 100 0.032
Mouse
nucleoside monophosphate metabolic process GO:0009123 191 0.032
determination of adult lifespan GO:0008340 2 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.030
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
stem cell maintenance GO:0019827 19 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.029
cellular ketone metabolic process GO:0042180 80 0.029
s shaped body morphogenesis GO:0072050 4 0.029
protein maturation GO:0051604 233 0.028
multicellular organismal aging GO:0010259 3 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
metanephric nephron tubule morphogenesis GO:0072282 1 0.028
mesodermal cell fate specification GO:0007501 2 0.028
metanephric tubule development GO:0072170 3 0.028
organ formation GO:0048645 3 0.028
somatic stem cell maintenance GO:0035019 4 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
cellular protein catabolic process GO:0044257 261 0.027
nucleoside catabolic process GO:0009164 408 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
coenzyme metabolic process GO:0006732 65 0.026
central nervous system development GO:0007417 123 0.026
Mouse
cellular amine metabolic process GO:0044106 41 0.026
response to lipid GO:0033993 206 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
protein processing GO:0016485 226 0.025
cellular response to gonadotropin stimulus GO:0071371 4 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
amine metabolic process GO:0009308 44 0.025
regulation of cellular component movement GO:0051270 334 0.024
Mouse
embryonic epithelial tube formation GO:0001838 4 0.024
Mouse
positive regulation of mesonephros development GO:0061213 2 0.024
stem cell differentiation GO:0048863 93 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
regulation of epithelial cell proliferation GO:0050678 113 0.024
regulation of neurogenesis GO:0050767 82 0.024
regulation of glomerulus development GO:0090192 3 0.024
negative regulation of protein metabolic process GO:0051248 391 0.023
nephric duct formation GO:0072179 1 0.023
neuron fate commitment GO:0048663 2 0.023
regulation of atpase activity GO:0043462 25 0.023
regulation of reactive oxygen species metabolic process GO:2000377 41 0.022
growth GO:0040007 202 0.022
Zebrafish Mouse
microtubule based transport GO:0010970 21 0.022
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
regulation of nervous system development GO:0051960 88 0.021
mesodermal cell fate commitment GO:0001710 2 0.021
negative regulation of neurogenesis GO:0050768 26 0.021
wnt signaling pathway GO:0016055 156 0.021
cranial nerve development GO:0021545 4 0.021
organophosphate catabolic process GO:0046434 430 0.021
neuron development GO:0048666 113 0.021
Zebrafish Mouse
negative regulation of organelle organization GO:0010639 126 0.021
negative regulation of cell cycle GO:0045786 193 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
segmentation GO:0035282 4 0.021
Zebrafish
regulation of proteolysis GO:0030162 293 0.021
chemical homeostasis GO:0048878 306 0.020
nephric duct development GO:0072176 4 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
retina development in camera type eye GO:0060041 15 0.020
oxidoreduction coenzyme metabolic process GO:0006733 19 0.020
regulation of cell cycle process GO:0010564 266 0.020
sensory perception GO:0007600 103 0.020
Mouse
neurological system process GO:0050877 163 0.020
Mouse
positive regulation of atpase activity GO:0032781 19 0.019
circulatory system development GO:0072359 262 0.019
Zebrafish
primary neural tube formation GO:0014020 3 0.019
Mouse
embryonic camera type eye morphogenesis GO:0048596 2 0.019
peripheral nervous system development GO:0007422 2 0.018
chemotaxis GO:0006935 157 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.018
epithelial cell proliferation GO:0050673 128 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
negative regulation of nervous system development GO:0051961 28 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
female gamete generation GO:0007292 2 0.017
regulation of cell motility GO:2000145 299 0.017
Mouse
response to inorganic substance GO:0010035 127 0.017
dna damage checkpoint GO:0000077 68 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
Mouse
response to oxygen containing compound GO:1901700 369 0.017
generation of neurons GO:0048699 152 0.016
Zebrafish Mouse
axon cargo transport GO:0008088 2 0.016
spermatid differentiation GO:0048515 4 0.016
Mouse
negative regulation of cytolysis GO:0045918 3 0.016
regulation of protein catabolic process GO:0042176 155 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
gtp metabolic process GO:0046039 239 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
epithelial cell differentiation GO:0030855 141 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
inner ear morphogenesis GO:0042472 4 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
golgi to plasma membrane cftr protein transport GO:0043000 1 0.016
pyruvate metabolic process GO:0006090 26 0.016
metanephric nephron tubule development GO:0072234 3 0.016
positive regulation of cellular protein catabolic process GO:1903364 37 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
regulation of locomotion GO:0040012 329 0.015
Mouse
rna processing GO:0006396 255 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
nephron tubule formation GO:0072079 1 0.015
cell cycle phase transition GO:0044770 173 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
Mouse
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cellular response to organonitrogen compound GO:0071417 124 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
Mouse
reactive oxygen species metabolic process GO:0072593 75 0.014
cell cycle checkpoint GO:0000075 117 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
transmembrane transport GO:0055085 399 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
negative regulation of mitotic cell cycle GO:0045930 102 0.014
epithelium development GO:0060429 227 0.014
Zebrafish Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
negative regulation of protein processing GO:0010955 142 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
response to abiotic stimulus GO:0009628 336 0.013
regulation of stem cell maintenance GO:2000036 4 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
single organism carbohydrate catabolic process GO:0044724 33 0.013
regeneration GO:0031099 4 0.013
anterior posterior axis specification GO:0009948 2 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
Mouse
nadh metabolic process GO:0006734 1 0.013
dna integrity checkpoint GO:0031570 71 0.013
developmental programmed cell death GO:0010623 3 0.013
regulation of kidney size GO:0035564 2 0.013
oogenesis GO:0048477 2 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.013
positive regulation of hormone biosynthetic process GO:0046886 4 0.013
regulation of cellular response to stress GO:0080135 244 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
regulation of thyroid stimulating hormone secretion GO:2000612 1 0.012
monosaccharide metabolic process GO:0005996 74 0.012
positive regulation of proteolysis GO:0045862 142 0.012
methylation GO:0032259 106 0.012
actin filament based process GO:0030029 224 0.012
optic nerve development GO:0021554 2 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
adult locomotory behavior GO:0008344 1 0.012
cellular modified amino acid metabolic process GO:0006575 64 0.012
regulation of protein processing GO:0070613 150 0.012
cell division GO:0051301 168 0.012
ras protein signal transduction GO:0007265 73 0.012
spermatid development GO:0007286 4 0.012
Mouse
cardiovascular system development GO:0072358 262 0.012
Zebrafish
retina layer formation GO:0010842 3 0.012
g2 dna damage checkpoint GO:0031572 26 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
negative regulation of proteolysis GO:0045861 132 0.012
cellular component disassembly GO:0022411 92 0.012
biological adhesion GO:0022610 331 0.012
embryonic camera type eye formation GO:0060900 2 0.012
somitogenesis GO:0001756 2 0.012
Zebrafish
neuron projection development GO:0031175 106 0.012
Mouse
cellular lipid metabolic process GO:0044255 303 0.012
brain development GO:0007420 97 0.012
Mouse
atp catabolic process GO:0006200 157 0.012
cochlea development GO:0090102 1 0.012
system process GO:0003008 349 0.012
Mouse
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
Mouse
apoptotic signaling pathway GO:0097190 268 0.012
sensory organ development GO:0007423 52 0.012
Mouse
hindbrain development GO:0030902 3 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
lipid metabolic process GO:0006629 381 0.011
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.011
mitotic cell cycle GO:0000278 326 0.011
cellular homeostasis GO:0019725 196 0.011
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.011
hexose metabolic process GO:0019318 55 0.011
cochlea morphogenesis GO:0090103 1 0.011
locomotory behavior GO:0007626 1 0.011
response to organic cyclic compound GO:0014070 204 0.011
tissue morphogenesis GO:0048729 96 0.011
Zebrafish Mouse
guanosine containing compound metabolic process GO:1901068 244 0.011
regulation of multi organism process GO:0043900 157 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of epithelial cell proliferation GO:0050679 65 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of transferase activity GO:0051338 355 0.011
associative learning GO:0008306 1 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.010
regulation of apoptotic process involved in morphogenesis GO:1902337 1 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
response to camp GO:0051591 25 0.010
gtp catabolic process GO:0006184 237 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
cellular response to peptide GO:1901653 59 0.010
olfactory bulb development GO:0021772 5 0.010
hormone transport GO:0009914 68 0.010
regulation of cell migration GO:0030334 289 0.010
rna splicing GO:0008380 131 0.010
mitotic dna damage checkpoint GO:0044773 28 0.010

BBS4 disease predictions

Disease DO term ID Size Probability Func Analog Org
thyroid carcinoma DOID:3963 13 0.205
papillary thyroid carcinoma DOID:3969 6 0.205
endocrine gland cancer DOID:170 26 0.205
thyroid cancer DOID:1781 13 0.205
cancer DOID:162 167 0.205
disease of cellular proliferation DOID:14566 174 0.205
organ system cancer DOID:0050686 164 0.205
meckel syndrome DOID:0050778 11 0.115
disease of metabolism DOID:0014667 295 0.041
sensory system disease DOID:0050155 203 0.041
nervous system disease DOID:863 431 0.041
joubert syndrome DOID:0050777 18 0.040
musculoskeletal system disease DOID:17 223 0.038
eye and adnexa disease DOID:1492 150 0.026
eye disease DOID:5614 149 0.025
central nervous system disease DOID:331 186 0.022
neurodegenerative disease DOID:1289 102 0.021
connective tissue disease DOID:65 109 0.020
retinal disease DOID:5679 118 0.018
cardiovascular system disease DOID:1287 106 0.016
inherited metabolic disorder DOID:655 242 0.016
muscular disease DOID:0080000 114 0.016
myopathy DOID:423 104 0.015
muscle tissue disease DOID:66 113 0.015
immune system disease DOID:2914 155 0.013
hematopoietic system disease DOID:74 100 0.012
brain disease DOID:936 73 0.012
bone disease DOID:0080001 88 0.012
amino acid metabolic disorder DOID:9252 50 0.012
kidney disease DOID:557 36 0.012
urinary system disease DOID:18 40 0.012