Homo sapiens

50 known processes

PPP4C

protein phosphatase 4, catalytic subunit

(Aliases: PPP4,PP4C,PPX,PPH3,PP4)

PPP4C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein dephosphorylation GO:0006470 81 0.978
Yeast
asymmetric neuroblast division GO:0055059 1 0.972
sperm egg recognition GO:0035036 3 0.958
cell cell recognition GO:0009988 4 0.938
asymmetric stem cell division GO:0098722 1 0.821
post embryonic development GO:0009791 2 0.692
Worm
organelle fission GO:0048285 149 0.663
Worm
dephosphorylation GO:0016311 209 0.648
binding of sperm to zona pellucida GO:0007339 3 0.514
mitotic cell cycle process GO:1903047 286 0.483
Worm
neuroblast division GO:0055057 1 0.423
negative regulation of multicellular organismal process GO:0051241 317 0.417
single organism membrane organization GO:0044802 268 0.397
negative regulation of protein metabolic process GO:0051248 391 0.358
mitotic cell cycle GO:0000278 326 0.344
Worm Fly
nuclear division GO:0000280 128 0.343
Worm
cell cycle checkpoint GO:0000075 117 0.332
Yeast
neuronal stem cell division GO:0036445 1 0.331
microtubule cytoskeleton organization GO:0000226 176 0.326
Worm
negative regulation of cellular component organization GO:0051129 235 0.271
Yeast
negative regulation of cytokinesis GO:0032466 3 0.271
toxin transport GO:1901998 4 0.270
protein processing GO:0016485 226 0.254
regulation of mitotic cell cycle GO:0007346 189 0.231
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.228
organelle assembly GO:0070925 176 0.222
membrane organization GO:0061024 292 0.209
mitotic nuclear division GO:0007067 119 0.209
wnt signaling pathway GO:0016055 156 0.205
cellular protein catabolic process GO:0044257 261 0.203
regulation of cellular response to stress GO:0080135 244 0.179
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.173
neuroblast proliferation GO:0007405 4 0.172
regulation of mapk cascade GO:0043408 262 0.157
cellular ketone metabolic process GO:0042180 80 0.147
regulation of neuroblast proliferation GO:1902692 3 0.147
peripheral nervous system development GO:0007422 2 0.142
regulation of cellular ketone metabolic process GO:0010565 50 0.123
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.123
regulation of stress activated mapk cascade GO:0032872 84 0.123
regulation of proteolysis GO:0030162 293 0.123
negative regulation of hydrolase activity GO:0051346 182 0.117
cell division GO:0051301 168 0.116
embryo development GO:0009790 123 0.112
Worm
spindle assembly GO:0051225 29 0.109
plasma membrane organization GO:0007009 115 0.107
multi organism localization GO:1902579 14 0.106
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.106
regulation of cellular component movement GO:0051270 334 0.102
interspecies interaction between organisms GO:0044419 156 0.101
cell development GO:0048468 328 0.100
Zebrafish
protein localization to membrane GO:0072657 160 0.099
monosaccharide metabolic process GO:0005996 74 0.097
mitochondrion organization GO:0007005 156 0.095
negative regulation of protein maturation GO:1903318 142 0.094
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.094
single organism reproductive process GO:0044702 98 0.094
regulation of protein serine threonine kinase activity GO:0071900 179 0.094
endomembrane system organization GO:0010256 196 0.093
negative regulation of catalytic activity GO:0043086 335 0.093
negative regulation of phosphatase activity GO:0010923 61 0.093
regulation of cell migration GO:0030334 289 0.093
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.087
regulation of cell cycle GO:0051726 393 0.083
Yeast Fly
carbohydrate metabolic process GO:0005975 207 0.082
Yeast
response to cytokine GO:0034097 232 0.082
Rat
reproductive process GO:0022414 106 0.082
Worm
sister chromatid segregation GO:0000819 54 0.081
cellular response to cytokine stimulus GO:0071345 181 0.081
Rat
organ morphogenesis GO:0009887 147 0.079
regulation of anatomical structure morphogenesis GO:0022603 286 0.079
double strand break repair GO:0006302 101 0.079
vesicle mediated transport GO:0016192 371 0.078
neurogenesis GO:0022008 169 0.078
Zebrafish Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.077
spindle organization GO:0007051 53 0.075
Worm
regulation of mitosis GO:0007088 63 0.075
monocarboxylic acid metabolic process GO:0032787 185 0.073
negative regulation of phosphorylation GO:0042326 174 0.073
signal transduction by phosphorylation GO:0023014 297 0.073
regulation of protein localization GO:0032880 296 0.068
regulation of dephosphorylation GO:0035303 96 0.068
single fertilization GO:0007338 11 0.068
negative regulation of catabolic process GO:0009895 104 0.066
divalent metal ion transport GO:0070838 152 0.066
negative regulation of apoptotic process GO:0043066 316 0.065
regulation of phosphatase activity GO:0010921 81 0.065
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.065
negative regulation of neural precursor cell proliferation GO:2000178 1 0.064
generation of neurons GO:0048699 152 0.062
Zebrafish
canonical wnt signaling pathway GO:0060070 116 0.062
biological adhesion GO:0022610 331 0.061
negative regulation of programmed cell death GO:0043069 321 0.061
negative regulation of cell death GO:0060548 345 0.061
spindle assembly involved in mitosis GO:0090307 12 0.059
negative regulation of locomotion GO:0040013 118 0.059
calcium ion transport GO:0006816 147 0.058
immune effector process GO:0002252 159 0.057
negative regulation of protein processing GO:0010955 142 0.057
regulation of protein processing GO:0070613 150 0.056
photoreceptor cell differentiation GO:0046530 2 0.056
protein stabilization GO:0050821 64 0.055
chromatin modification GO:0016568 298 0.055
cell cycle phase transition GO:0044770 173 0.054
Yeast
defense response GO:0006952 315 0.054
negative regulation of phosphate metabolic process GO:0045936 267 0.053
negative regulation of stress activated mapk cascade GO:0032873 19 0.052
multicellular organism reproduction GO:0032504 42 0.051
Worm
modification dependent protein catabolic process GO:0019941 209 0.051
amine metabolic process GO:0009308 44 0.050
negative regulation of intracellular signal transduction GO:1902532 183 0.050
regulation of endopeptidase activity GO:0052548 170 0.049
protein polymerization GO:0051258 71 0.049
negative regulation of stem cell proliferation GO:2000647 3 0.049
membrane fusion GO:0061025 43 0.048
regulation of cellular amine metabolic process GO:0033238 11 0.048
regulation of calcium ion transport GO:0051924 79 0.048
negative regulation of proteolysis GO:0045861 132 0.047
cell adhesion GO:0007155 325 0.047
regulation of chromosome segregation GO:0051983 44 0.047
protein catabolic process GO:0030163 325 0.047
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
stress activated protein kinase signaling cascade GO:0031098 94 0.047
protein maturation GO:0051604 233 0.047
regulation of locomotion GO:0040012 329 0.046
ribonucleoside catabolic process GO:0042454 406 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
spindle assembly checkpoint GO:0071173 17 0.046
cellular component morphogenesis GO:0032989 314 0.045
Zebrafish
negative regulation of developmental process GO:0051093 247 0.045
positive regulation of cellular component organization GO:0051130 376 0.045
myeloid cell differentiation GO:0030099 117 0.044
regulation of voltage gated calcium channel activity GO:1901385 7 0.044
glycosylation GO:0070085 71 0.044
protein localization to plasma membrane GO:0072659 93 0.043
fertilization GO:0009566 12 0.043
stress activated mapk cascade GO:0051403 93 0.042
negative regulation of cell cycle process GO:0010948 121 0.042
Yeast
ncrna processing GO:0034470 83 0.041
nucleotide catabolic process GO:0009166 408 0.041
mitotic sister chromatid segregation GO:0000070 53 0.041
cation transport GO:0006812 331 0.041
somatic stem cell division GO:0048103 1 0.040
negative regulation of mitotic cell cycle GO:0045930 102 0.040
developmental programmed cell death GO:0010623 3 0.040
negative regulation of transport GO:0051051 176 0.038
regulation of leukocyte apoptotic process GO:2000106 25 0.038
mapk cascade GO:0000165 288 0.038
reproduction GO:0000003 63 0.038
Yeast Worm
metal ion transport GO:0030001 272 0.038
positive regulation of kinase activity GO:0033674 204 0.038
negative regulation of cell differentiation GO:0045596 171 0.037
response to organonitrogen compound GO:0010243 156 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
mitotic sister chromatid separation GO:0051306 18 0.037
ion transmembrane transport GO:0034220 338 0.037
vesicle organization GO:0016050 62 0.037
embryo development ending in birth or egg hatching GO:0009792 34 0.037
Worm
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.036
regulation of mitotic cell cycle phase transition GO:1901990 118 0.036
cellular chemical homeostasis GO:0055082 180 0.036
Yeast
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.036
metaphase anaphase transition of cell cycle GO:0044784 21 0.036
multi organism reproductive process GO:0044703 54 0.035
Worm
oogenesis GO:0048477 2 0.035
cellular cation homeostasis GO:0030003 163 0.035
sensory organ development GO:0007423 52 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.034
purine ribonucleoside catabolic process GO:0046130 398 0.033
cellular macromolecule catabolic process GO:0044265 380 0.032
neuromuscular junction development GO:0007528 3 0.032
response to virus GO:0009615 126 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.032
regulation of meiotic cell cycle GO:0051445 4 0.032
Yeast
mitotic cell cycle checkpoint GO:0007093 68 0.032
establishment or maintenance of neuroblast polarity GO:0045196 1 0.032
response to interleukin 1 GO:0070555 47 0.031
Rat
segmentation GO:0035282 4 0.031
microtubule based process GO:0007017 210 0.031
Worm Fly
central nervous system development GO:0007417 123 0.030
Zebrafish
response to biotic stimulus GO:0009607 276 0.030
cell projection organization GO:0030030 252 0.030
Zebrafish
proteasomal protein catabolic process GO:0010498 176 0.030
demethylation GO:0070988 37 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
taxis GO:0042330 157 0.030
negative regulation of cell proliferation GO:0008285 228 0.030
female gamete generation GO:0007292 2 0.030
negative regulation of cell development GO:0010721 48 0.029
autophagy GO:0006914 88 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
transmembrane transport GO:0055085 399 0.029
regulation of synaptic plasticity GO:0048167 3 0.028
nuclear envelope reassembly GO:0031468 3 0.028
glycerolipid metabolic process GO:0046486 107 0.028
positive regulation of transferase activity GO:0051347 227 0.028
purine containing compound catabolic process GO:0072523 411 0.028
morphogenesis of an epithelium GO:0002009 60 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
positive regulation of organelle organization GO:0010638 195 0.027
negative regulation of cell cycle GO:0045786 193 0.027
Yeast
regulation of anatomical structure size GO:0090066 101 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
response to external biotic stimulus GO:0043207 261 0.026
organophosphate catabolic process GO:0046434 430 0.026
lipid localization GO:0010876 106 0.026
stem cell division GO:0017145 2 0.025
regulation of cell motility GO:2000145 299 0.025
cell type specific apoptotic process GO:0097285 125 0.025
circulatory system development GO:0072359 262 0.024
Zebrafish
determination of adult lifespan GO:0008340 2 0.024
response to oxygen containing compound GO:1901700 369 0.024
Yeast
embryonic eye morphogenesis GO:0048048 2 0.024
response to metal ion GO:0010038 84 0.024
establishment of nucleus localization GO:0040023 1 0.024
regulation of jnk cascade GO:0046328 73 0.024
atp metabolic process GO:0046034 176 0.024
leukocyte apoptotic process GO:0071887 31 0.023
response to nitrogen compound GO:1901698 184 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
innate immune response GO:0045087 178 0.023
negative regulation of transporter activity GO:0032410 25 0.023
synaptic vesicle endocytosis GO:0048488 2 0.023
mitotic spindle organization GO:0007052 27 0.023
Worm
regulation of mitotic sister chromatid separation GO:0010965 27 0.022
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.022
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.022
spindle checkpoint GO:0031577 26 0.022
regulation of secretion by cell GO:1903530 177 0.022
covalent chromatin modification GO:0016569 254 0.022
mitotic nuclear envelope reassembly GO:0007084 3 0.022
response to cocaine GO:0042220 1 0.022
positive regulation of secretion GO:0051047 116 0.022
regulation of ion transport GO:0043269 189 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
brain development GO:0007420 97 0.021
Zebrafish
multi organism transport GO:0044766 14 0.021
double strand break repair via homologous recombination GO:0000724 50 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
negative regulation of chromosome organization GO:2001251 48 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
lymphocyte activation GO:0046649 133 0.020
dna repair GO:0006281 198 0.020
negative regulation of dephosphorylation GO:0035305 63 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
protein localization to organelle GO:0033365 280 0.020
chromosome segregation GO:0007059 114 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
immune system development GO:0002520 195 0.020
viral life cycle GO:0019058 132 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
g2 m transition of mitotic cell cycle GO:0000086 41 0.019
negative regulation of organelle organization GO:0010639 126 0.019
Yeast
spindle elongation GO:0051231 4 0.019
regulation of transmembrane transport GO:0034762 139 0.019
oxidation reduction process GO:0055114 396 0.019
Yeast
regulation of proteasomal protein catabolic process GO:0061136 87 0.019
urogenital system development GO:0001655 65 0.019
cellular homeostasis GO:0019725 196 0.019
Yeast
regulation of cell development GO:0060284 161 0.019
cytoskeleton dependent cytokinesis GO:0061640 22 0.019
trna metabolic process GO:0006399 35 0.019
regulation of nuclear division GO:0051783 65 0.019
Yeast
single organism membrane fusion GO:0044801 37 0.019
regulation of cell cycle checkpoint GO:1901976 21 0.018
Yeast
secretion by cell GO:0032940 226 0.018
immune response GO:0006955 307 0.018
exocytosis GO:0006887 71 0.018
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.018
dna integrity checkpoint GO:0031570 71 0.018
Yeast
tissue morphogenesis GO:0048729 96 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
protein folding GO:0006457 38 0.018
locomotory behavior GO:0007626 1 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.017
cell part morphogenesis GO:0032990 137 0.017
Zebrafish
regulation of protein transport GO:0051223 213 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
cation homeostasis GO:0055080 189 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
regulation of transporter activity GO:0032409 82 0.017
meiotic cell cycle GO:0051321 13 0.017
Yeast Worm
cellular amino acid metabolic process GO:0006520 116 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
mesenchyme development GO:0060485 59 0.017
response to other organism GO:0051707 261 0.017
positive regulation of apoptotic process GO:0043065 246 0.016
regeneration GO:0031099 4 0.016
endocytosis GO:0006897 159 0.016
actin polymerization or depolymerization GO:0008154 56 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of map kinase activity GO:0043405 108 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
nervous system development GO:0007399 293 0.016
Zebrafish Fly
negative regulation of sister chromatid segregation GO:0033046 17 0.016
negative regulation of nervous system development GO:0051961 28 0.016
chemical homeostasis GO:0048878 306 0.016
Yeast
response to fungus GO:0009620 4 0.016
spermatid differentiation GO:0048515 4 0.016
growth GO:0040007 202 0.016
leukocyte activation GO:0045321 164 0.016
neuron development GO:0048666 113 0.016
Zebrafish
establishment of rna localization GO:0051236 39 0.016
negative regulation of mapk cascade GO:0043409 56 0.016
nuclear transcribed mrna catabolic process GO:0000956 48 0.016
motor neuron axon guidance GO:0008045 2 0.016
epithelium development GO:0060429 227 0.016
neuron differentiation GO:0030182 138 0.015
Zebrafish
renal system development GO:0072001 63 0.015
cilium organization GO:0044782 68 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
actin filament organization GO:0007015 128 0.015
hemopoiesis GO:0030097 180 0.015
cell morphogenesis involved in differentiation GO:0000904 144 0.015
Zebrafish
multi organism cellular process GO:0044764 156 0.015
endosomal transport GO:0016197 129 0.015
secretion GO:0046903 254 0.015
sexual reproduction GO:0019953 37 0.015
viral process GO:0016032 146 0.015
regulation of metal ion transport GO:0010959 120 0.015
regulation of growth GO:0040008 165 0.015
metal ion homeostasis GO:0055065 169 0.015
regulation of myeloid cell differentiation GO:0045637 81 0.015
nucleoside catabolic process GO:0009164 408 0.015
eye photoreceptor cell differentiation GO:0001754 2 0.014
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.014
positive regulation of cell motility GO:2000147 177 0.014
regulation of peptidase activity GO:0052547 180 0.014
exit from mitosis GO:0010458 10 0.014
single organism cellular localization GO:1902580 332 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.014
cell substrate adhesion GO:0031589 132 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
organelle localization GO:0051640 84 0.014
receptor mediated endocytosis GO:0006898 84 0.014
respiratory system development GO:0060541 22 0.014
cell cycle g2 m phase transition GO:0044839 43 0.014
negative regulation of cell division GO:0051782 31 0.014
Yeast
regulation of cell projection organization GO:0031344 107 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
stem cell development GO:0048864 69 0.014
positive regulation of smoothened signaling pathway GO:0045880 4 0.014
protein autophosphorylation GO:0046777 123 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of transferase activity GO:0051338 355 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
Worm
lipid metabolic process GO:0006629 381 0.013
cytokine production GO:0001816 247 0.013
cell activation GO:0001775 213 0.013
response to tumor necrosis factor GO:0034612 76 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
cell communication by electrical coupling involved in cardiac conduction GO:0086064 3 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
negative regulation of jnk cascade GO:0046329 16 0.013
protein oligomerization GO:0051259 173 0.013
respiratory tube development GO:0030323 20 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
small molecule biosynthetic process GO:0044283 157 0.013
cytokinesis GO:0000910 96 0.013
negative regulation of protein modification process GO:0031400 200 0.013
regulation of protein maturation GO:1903317 150 0.012
mesenchymal cell differentiation GO:0048762 52 0.012
regulation of cell differentiation GO:0045595 393 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
snrna metabolic process GO:0016073 15 0.012
cellular lipid metabolic process GO:0044255 303 0.012
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.012
gonad development GO:0008406 34 0.012
multicellular organismal aging GO:0010259 3 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.012
nuclear migration GO:0007097 1 0.012
lipid storage GO:0019915 28 0.012
epithelial to mesenchymal transition GO:0001837 48 0.012
positive regulation of developmental process GO:0051094 314 0.012
calcium ion transmembrane transport GO:0070588 76 0.012
lipid biosynthetic process GO:0008610 177 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.011
divalent inorganic cation transport GO:0072511 158 0.011
cranial nerve morphogenesis GO:0021602 1 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
ribosome biogenesis GO:0042254 48 0.011
positive regulation of protein localization to nucleus GO:1900182 48 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
synaptic vesicle recycling GO:0036465 3 0.011
developmental process involved in reproduction GO:0003006 66 0.011
establishment of organelle localization GO:0051656 59 0.011
regulation of cell cycle process GO:0010564 266 0.011
Yeast
establishment of protein localization to membrane GO:0090150 121 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 16 0.011
jnk cascade GO:0007254 80 0.011
heart development GO:0007507 95 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
distal tubule development GO:0072017 4 0.011
behavior GO:0007610 112 0.011
Worm
sensory perception of pain GO:0019233 4 0.011
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.011
response to alkaloid GO:0043279 20 0.011
snrna processing GO:0016180 14 0.011
regulation of double strand break repair GO:2000779 22 0.011
establishment of protein localization to plasma membrane GO:0090002 68 0.011
golgi vesicle transport GO:0048193 80 0.011
response to endoplasmic reticulum stress GO:0034976 49 0.011
trachea development GO:0060438 1 0.011
centrosome organization GO:0051297 58 0.011
retina layer formation GO:0010842 3 0.011
regulation of sister chromatid segregation GO:0033045 27 0.011
apoptotic signaling pathway GO:0097190 268 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
dna damage checkpoint GO:0000077 68 0.010
Yeast
ion homeostasis GO:0050801 230 0.010
anatomical structure homeostasis GO:0060249 100 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
cytokine mediated signaling pathway GO:0019221 109 0.010
eye development GO:0001654 42 0.010
regulation of calcium ion transmembrane transport GO:1903169 28 0.010

PPP4C disease predictions

Disease DO term ID Size Probability Func Analog Org