Homo sapiens

121 known processes

TMEM59

transmembrane protein 59

(Aliases: FLJ42977,HSPC001,C1orf8)

TMEM59 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
store operated calcium entry GO:0002115 3 0.088
intracellular protein transport GO:0006886 270 0.073
determination of adult lifespan GO:0008340 2 0.064
defense response GO:0006952 315 0.057
negative regulation of glycoprotein metabolic process GO:1903019 8 0.049
post embryonic development GO:0009791 2 0.047
apoptotic signaling pathway GO:0097190 268 0.047
cytoplasmic transport GO:0016482 379 0.043
immune response GO:0006955 307 0.040
innate immune response GO:0045087 178 0.040
positive regulation of immune system process GO:0002684 283 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
negative regulation of protein processing GO:0010955 142 0.038
positive regulation of apoptotic process GO:0043065 246 0.029
response to other organism GO:0051707 261 0.029
multicellular organismal aging GO:0010259 3 0.029
protein localization to organelle GO:0033365 280 0.027
positive regulation of immune response GO:0050778 159 0.027
membrane organization GO:0061024 292 0.027
lipid biosynthetic process GO:0008610 177 0.027
response to external biotic stimulus GO:0043207 261 0.027
regulation of protein maturation GO:1903317 150 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
single organism membrane organization GO:0044802 268 0.024
blood vessel morphogenesis GO:0048514 162 0.024
secretion GO:0046903 254 0.023
regulation of secretion GO:0051046 194 0.023
positive regulation of transport GO:0051050 336 0.023
mapk cascade GO:0000165 288 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
golgi to vacuole transport GO:0006896 3 0.022
cellular lipid metabolic process GO:0044255 303 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 3 0.020
response to biotic stimulus GO:0009607 276 0.020
regulation of protein processing GO:0070613 150 0.020
regulation of proteolysis GO:0030162 293 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
negative regulation of developmental process GO:0051093 247 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
regulation of intracellular transport GO:0032386 195 0.019
regulation of cellular response to stress GO:0080135 244 0.019
positive regulation of cell death GO:0010942 263 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
regulation of peptidase activity GO:0052547 180 0.018
regulation of immune response GO:0050776 201 0.018
viral process GO:0016032 146 0.018
immune effector process GO:0002252 159 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
single organism cellular localization GO:1902580 332 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
lipid metabolic process GO:0006629 381 0.017
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.017
regulation of defense response GO:0031347 154 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
protein processing GO:0016485 226 0.017
cholesterol transport GO:0030301 39 0.017
regulation of leukocyte activation GO:0002694 115 0.017
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.017
cellular protein catabolic process GO:0044257 261 0.017
regulation of exocytosis GO:0017157 46 0.017
amyloid precursor protein biosynthetic process GO:0042983 4 0.016
wnt signaling pathway GO:0016055 156 0.016
post golgi vesicle mediated transport GO:0006892 36 0.016
actin filament based process GO:0030029 224 0.016
response to bacterium GO:0009617 144 0.016
locomotory behavior GO:0007626 1 0.016
positive regulation of secretion GO:0051047 116 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
glycoprotein biosynthetic process GO:0009101 91 0.015
cellular ketone metabolic process GO:0042180 80 0.015
small molecule biosynthetic process GO:0044283 157 0.015
regulation of membrane potential GO:0042391 95 0.015
cellular amide metabolic process GO:0043603 69 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
protein maturation GO:0051604 233 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
oogenesis GO:0048477 2 0.014
cellular component morphogenesis GO:0032989 314 0.014
exocytosis GO:0006887 71 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
macroautophagy GO:0016236 39 0.014
multi organism cellular process GO:0044764 156 0.014
defense response to other organism GO:0098542 129 0.014
female gamete generation GO:0007292 2 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
peptide metabolic process GO:0006518 51 0.014
response to virus GO:0009615 126 0.014
negative regulation of protein maturation GO:1903318 142 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
golgi vesicle transport GO:0048193 80 0.013
microtubule based process GO:0007017 210 0.013
calcium ion homeostasis GO:0055074 122 0.013
positive regulation of leukocyte activation GO:0002696 80 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
interspecies interaction between organisms GO:0044419 156 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
positive regulation of catabolic process GO:0009896 310 0.013
segmentation GO:0035282 4 0.013
defense response to bacterium GO:0042742 63 0.013
viral life cycle GO:0019058 132 0.013
protein catabolic process GO:0030163 325 0.013
protein stabilization GO:0050821 64 0.013
response to oxidative stress GO:0006979 121 0.012
memory GO:0007613 3 0.012
anion transport GO:0006820 161 0.012
glycoprotein metabolic process GO:0009100 110 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
regulation of transferase activity GO:0051338 355 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
cell development GO:0048468 328 0.012
hormone metabolic process GO:0042445 61 0.012
regulation of ion transport GO:0043269 189 0.012
immune system development GO:0002520 195 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
nervous system development GO:0007399 293 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
regulation of cytokine production GO:0001817 232 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
regulation of cell activation GO:0050865 125 0.012
protein ubiquitination GO:0016567 314 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
regulation of complement activation classical pathway GO:0030450 3 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
response to oxygen containing compound GO:1901700 369 0.011
regulation of glycoprotein metabolic process GO:1903018 19 0.011
alcohol biosynthetic process GO:0046165 52 0.011
regulation of protein localization GO:0032880 296 0.011
regulation of microtubule based process GO:0032886 74 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of cell cycle GO:0045786 193 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
regulation of protein stability GO:0031647 87 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
regulation of amyloid precursor protein biosynthetic process GO:0042984 4 0.011
positive regulation of exocytosis GO:0045921 35 0.011
regulation of cellular component movement GO:0051270 334 0.011
cellular chemical homeostasis GO:0055082 180 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of cell differentiation GO:0045595 393 0.011
autophagy GO:0006914 88 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
blastoderm segmentation GO:0007350 2 0.011
cell projection organization GO:0030030 252 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
cellular response to oxidative stress GO:0034599 85 0.011
myosin filament assembly GO:0031034 2 0.011
cholesterol homeostasis GO:0042632 28 0.010
regulation of immune effector process GO:0002697 91 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
positive regulation of natural killer cell activation GO:0032816 8 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
spermatid differentiation GO:0048515 4 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
peripheral nervous system development GO:0007422 2 0.010
regulation of mapk cascade GO:0043408 262 0.010
vesicle mediated transport GO:0016192 371 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
regulation of protein kinase activity GO:0045859 289 0.010
positive regulation of lymphocyte activation GO:0051251 73 0.010

TMEM59 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.532
inherited metabolic disorder DOID:655 242 0.225
amino acid metabolic disorder DOID:9252 50 0.038
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026
gastrointestinal system disease DOID:77 36 0.022
immune system disease DOID:2914 155 0.022
lysosomal storage disease DOID:3211 47 0.020
acquired metabolic disease DOID:0060158 58 0.018
sensory system disease DOID:0050155 203 0.011
nervous system disease DOID:863 431 0.011
hematopoietic system disease DOID:74 100 0.011
central nervous system disease DOID:331 186 0.011
organic acidemia DOID:0060159 14 0.010