Homo sapiens

0 known processes

PARP12

poly (ADP-ribose) polymerase family, member 12

(Aliases: ZC3H1,ZC3HDC1,MST109,FLJ22693,MSTP109)

PARP12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to virus GO:0051607 71 0.964
Human
positive regulation of interferon beta production GO:0032728 17 0.931
Human
viral life cycle GO:0019058 132 0.861
Human
negative regulation of viral process GO:0048525 66 0.822
Human
multi organism cellular process GO:0044764 156 0.738
Human
response to biotic stimulus GO:0009607 276 0.715
Human
negative regulation of viral genome replication GO:0045071 35 0.560
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.551
Human
response to other organism GO:0051707 261 0.511
Human
defense response to other organism GO:0098542 129 0.511
Human
immune effector process GO:0002252 159 0.486
Human
defense response GO:0006952 315 0.477
Human
positive regulation of cytokine production GO:0001819 167 0.449
Human
viral process GO:0016032 146 0.430
Human
interspecies interaction between organisms GO:0044419 156 0.411
Human
response to external biotic stimulus GO:0043207 261 0.411
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.394
Human
immune response GO:0006955 307 0.390
negative regulation of multi organism process GO:0043901 92 0.339
Human
regulation of multi organism process GO:0043900 157 0.317
Human
cytoplasmic transport GO:0016482 379 0.295
innate immune response GO:0045087 178 0.257
response to cytokine GO:0034097 232 0.244
response to virus GO:0009615 126 0.230
Human
negative regulation of gene silencing by rna GO:0060967 3 0.191
regulation of fas signaling pathway GO:1902044 2 0.187
nuclear transport GO:0051169 179 0.185
nucleocytoplasmic transport GO:0006913 176 0.184
regulation of innate immune response GO:0045088 97 0.183
Human
immune response activating signal transduction GO:0002757 90 0.181
Human
protein modification by small protein conjugation GO:0032446 342 0.181
activation of innate immune response GO:0002218 55 0.180
Human
positive regulation of immune system process GO:0002684 283 0.162
Human
positive regulation of interferon alpha production GO:0032727 11 0.152
Human
regulation of viral genome replication GO:0045069 48 0.144
Human
regulation of interferon alpha production GO:0032647 11 0.138
Human
pattern recognition receptor signaling pathway GO:0002221 48 0.131
Human
cytokine production GO:0001816 247 0.121
Human
intracellular protein transport GO:0006886 270 0.114
regulation of cytokine production GO:0001817 232 0.114
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.113
positive regulation of innate immune response GO:0045089 79 0.110
Human
immune response regulating signaling pathway GO:0002764 97 0.107
Human
regulation of cellular component movement GO:0051270 334 0.101
innate immune response activating signal transduction GO:0002758 48 0.099
Human
negative regulation of multicellular organismal process GO:0051241 317 0.098
regulation of intracellular transport GO:0032386 195 0.095
positive regulation of defense response GO:0031349 87 0.095
Human
fas signaling pathway GO:0036337 3 0.093
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.084
posttranscriptional regulation of gene expression GO:0010608 213 0.078
rna interference GO:0016246 4 0.073
gene silencing by mirna GO:0035195 23 0.073
regulation of viral process GO:0050792 103 0.071
Human
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.071
Human
protein localization to organelle GO:0033365 280 0.069
nucleoside phosphate biosynthetic process GO:1901293 109 0.068
regulation of immune response GO:0050776 201 0.067
Human
regulation of establishment of protein localization GO:0070201 242 0.066
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.066
glycosylation GO:0070085 71 0.063
regulation of defense response GO:0031347 154 0.063
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.062
regulation of protein transport GO:0051223 213 0.062
regulation of cell migration GO:0030334 289 0.059
protein import into nucleus GO:0006606 104 0.059
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.058
regulation of nucleocytoplasmic transport GO:0046822 98 0.056
regulation of cytoplasmic transport GO:1903649 149 0.056
regulation of cell motility GO:2000145 299 0.052
rna processing GO:0006396 255 0.051
macromolecule glycosylation GO:0043413 63 0.049
ribonucleoprotein complex biogenesis GO:0022613 116 0.049
regulation of protein localization GO:0032880 296 0.049
lipoprotein metabolic process GO:0042157 42 0.047
dsrna fragmentation GO:0031050 13 0.047
negative regulation of catalytic activity GO:0043086 335 0.046
regulation of apoptotic signaling pathway GO:2001233 175 0.045
regulation of type i interferon production GO:0032479 26 0.044
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.044
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.043
purine nucleotide biosynthetic process GO:0006164 84 0.043
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.043
Human
cellular response to nitrogen compound GO:1901699 144 0.042
protein acylation GO:0043543 138 0.042
response to bacterium GO:0009617 144 0.042
anatomical structure homeostasis GO:0060249 100 0.042
single organism cellular localization GO:1902580 332 0.041
response to dsrna GO:0043331 25 0.040
negative regulation of cell motility GO:2000146 104 0.040
protein targeting GO:0006605 187 0.039
negative regulation of transport GO:0051051 176 0.039
regulation of locomotion GO:0040012 329 0.038
response to organic cyclic compound GO:0014070 204 0.037
protein import GO:0017038 130 0.036
regulation of angiogenesis GO:0045765 92 0.036
regulation of immune effector process GO:0002697 91 0.036
Human
regulation of transferase activity GO:0051338 355 0.036
positive regulation of type i interferon production GO:0032481 20 0.036
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
cellular response to cytokine stimulus GO:0071345 181 0.034
regulation of protein localization to nucleus GO:1900180 85 0.034
single organism nuclear import GO:1902593 104 0.033
ncrna processing GO:0034470 83 0.033
regulation of interferon beta production GO:0032648 22 0.033
Human
metal ion transport GO:0030001 272 0.032
protein glycosylation GO:0006486 62 0.032
regulation of intracellular protein transport GO:0033157 123 0.032
positive regulation of multi organism process GO:0043902 56 0.032
Human
atp catabolic process GO:0006200 157 0.031
response to type i interferon GO:0034340 14 0.031
positive regulation of cell death GO:0010942 263 0.031
regulation of vasculature development GO:1901342 97 0.030
purine containing compound catabolic process GO:0072523 411 0.030
purine nucleoside monophosphate metabolic process GO:0009126 186 0.030
protein localization to nucleus GO:0034504 136 0.030
viral transcription GO:0019083 35 0.029
regulation of cell cycle GO:0051726 393 0.029
nuclear export GO:0051168 69 0.028
covalent chromatin modification GO:0016569 254 0.028
gene silencing GO:0016458 49 0.028
protein targeting to nucleus GO:0044744 104 0.027
regulation of defense response to virus GO:0050688 33 0.027
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
interferon beta production GO:0032608 23 0.027
Human
positive regulation of intracellular protein transport GO:0090316 76 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
detection of muramyl dipeptide GO:0032498 1 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.027
negative regulation of protein modification process GO:0031400 200 0.026
viral gene expression GO:0019080 35 0.026
lipoprotein biosynthetic process GO:0042158 33 0.026
negative regulation of locomotion GO:0040013 118 0.026
ncrna metabolic process GO:0034660 108 0.026
regulation of protein kinase activity GO:0045859 289 0.026
epithelial cell migration GO:0010631 119 0.026
purine containing compound biosynthetic process GO:0072522 88 0.026
ribonucleoprotein complex assembly GO:0022618 78 0.026
positive regulation of protein import into nucleus GO:0042307 46 0.025
tissue migration GO:0090130 119 0.025
negative regulation of protein transport GO:0051224 75 0.025
establishment of protein localization to organelle GO:0072594 172 0.024
hemopoiesis GO:0030097 180 0.024
atp metabolic process GO:0046034 176 0.024
protein myristoylation GO:0018377 1 0.024
posttranscriptional gene silencing GO:0016441 25 0.024
negative regulation of immune system process GO:0002683 136 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.023
cellular protein catabolic process GO:0044257 261 0.023
ameboidal type cell migration GO:0001667 135 0.023
positive regulation of protein localization to nucleus GO:1900182 48 0.023
protein ubiquitination GO:0016567 314 0.023
regulation of rig i signaling pathway GO:0039535 6 0.023
Human
positive regulation of immune effector process GO:0002699 40 0.023
Human
regulation of kinase activity GO:0043549 314 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
ribonucleoside monophosphate catabolic process GO:0009158 158 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
Human
modification dependent protein catabolic process GO:0019941 209 0.023
regulation of response to external stimulus GO:0032101 222 0.023
Human
viral genome replication GO:0019079 50 0.022
Human
response to interferon gamma GO:0034341 39 0.022
response to oxygen containing compound GO:1901700 369 0.022
negative regulation of cellular component movement GO:0051271 106 0.022
regulation of protein export from nucleus GO:0046825 15 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
ribonucleoprotein complex subunit organization GO:0071826 81 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
regulation of gene expression epigenetic GO:0040029 73 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
apoptotic signaling pathway GO:0097190 268 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
negative regulation of intracellular transport GO:0032387 60 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
nucleotide catabolic process GO:0009166 408 0.020
regulation of epithelial cell migration GO:0010632 93 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
negative regulation of cell migration GO:0030336 102 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
cytokine metabolic process GO:0042107 38 0.020
response to nitrogen compound GO:1901698 184 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.020
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
production of small rna involved in gene silencing by rna GO:0070918 13 0.020
posttranscriptional gene silencing by rna GO:0035194 25 0.020
multicellular organismal homeostasis GO:0048871 67 0.020
vasculature development GO:0001944 181 0.019
mrna metabolic process GO:0016071 175 0.019
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
positive regulation of mhc class i biosynthetic process GO:0045345 4 0.019
negative regulation of cytokine production GO:0001818 82 0.019
regulation of response to biotic stimulus GO:0002831 55 0.019
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
negative regulation of protein phosphorylation GO:0001933 140 0.018
biological adhesion GO:0022610 331 0.018
nuclear import GO:0051170 106 0.018
positive regulation of transport GO:0051050 336 0.018
angiogenesis GO:0001525 147 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
negative regulation of epithelial cell migration GO:0010633 38 0.018
ion transmembrane transport GO:0034220 338 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
post embryonic development GO:0009791 2 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
chemical homeostasis GO:0048878 306 0.017
blood vessel development GO:0001568 172 0.017
protein sumoylation GO:0016925 25 0.017
glycoprotein metabolic process GO:0009100 110 0.017
negative regulation of protein maturation GO:1903318 142 0.017
protein export from nucleus GO:0006611 29 0.017
regulation of viral transcription GO:0046782 34 0.017
activation of immune response GO:0002253 114 0.017
Human
positive regulation of transcription factor import into nucleus GO:0042993 25 0.017
negative regulation of type i interferon production GO:0032480 5 0.016
negative regulation of defense response GO:0031348 47 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
circulatory system development GO:0072359 262 0.016
negative regulation of transferase activity GO:0051348 124 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
blood vessel morphogenesis GO:0048514 162 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
positive regulation of immune response GO:0050778 159 0.016
Human
secretion by cell GO:0032940 226 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
leukocyte activation GO:0045321 164 0.016
mapk cascade GO:0000165 288 0.016
regulation of proteolysis GO:0030162 293 0.016
female gamete generation GO:0007292 2 0.015
chromatin organization GO:0006325 351 0.015
regulation of protein targeting GO:1903533 91 0.015
epithelium migration GO:0090132 119 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
interferon alpha production GO:0032607 11 0.015
Human
monosaccharide metabolic process GO:0005996 74 0.015
glucose metabolic process GO:0006006 45 0.015
negative regulation of intracellular protein transport GO:0090317 42 0.015
negative regulation of cell cycle GO:0045786 193 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.014
type i interferon production GO:0032606 27 0.014
Human
cellular response to oxygen containing compound GO:1901701 276 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of cell differentiation GO:0045595 393 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
Human
positive regulation of protein transport GO:0051222 135 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
cardiovascular system development GO:0072358 262 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
negative regulation of developmental process GO:0051093 247 0.013
determination of adult lifespan GO:0008340 2 0.013
regulation of dna binding GO:0051101 37 0.013
nucleoside catabolic process GO:0009164 408 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
organophosphate catabolic process GO:0046434 430 0.013
protein oligomerization GO:0051259 173 0.013
telomere maintenance GO:0000723 32 0.013
regulation of binding GO:0051098 111 0.013
negative regulation of endothelial cell migration GO:0010596 29 0.013
response to lipid GO:0033993 206 0.013
cell adhesion GO:0007155 325 0.013
ras protein signal transduction GO:0007265 73 0.013
negative regulation of cytoplasmic transport GO:1903650 46 0.013
cell fate determination GO:0001709 3 0.013
regulation of dna metabolic process GO:0051052 153 0.013
regulation of mapk cascade GO:0043408 262 0.012
regulation of cell activation GO:0050865 125 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
negative regulation of kinase activity GO:0033673 106 0.012
gene silencing by rna GO:0031047 26 0.012
regulation of secretion by cell GO:1903530 177 0.012
response to peptidoglycan GO:0032494 3 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
protein modification by small protein removal GO:0070646 92 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
positive regulation of proteolysis GO:0045862 142 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
endothelial cell migration GO:0043542 86 0.012
protein lipidation GO:0006497 33 0.012
osteoblast differentiation GO:0001649 92 0.012
chromatin modification GO:0016568 298 0.012
cellular response to type i interferon GO:0071357 12 0.012
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.012
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
negative regulation of apoptotic process GO:0043066 316 0.011
protein autoubiquitination GO:0051865 37 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
response to abiotic stimulus GO:0009628 336 0.011
cell cycle arrest GO:0007050 71 0.011
cation transport GO:0006812 331 0.011
protein polyubiquitination GO:0000209 110 0.011
negative regulation of immune effector process GO:0002698 38 0.011
positive regulation of viral entry into host cell GO:0046598 3 0.011
regulation of protein import into nucleus GO:0042306 78 0.011
cellular response to dsrna GO:0071359 19 0.011
protein maturation GO:0051604 233 0.011
t cell proliferation GO:0042098 45 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
pre mirna processing GO:0031054 8 0.011
protein autophosphorylation GO:0046777 123 0.011
multicellular organismal aging GO:0010259 3 0.011
multi organism metabolic process GO:0044033 41 0.011
transmembrane transport GO:0055085 399 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
double strand break repair GO:0006302 101 0.011
rna modification GO:0009451 27 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
rig i signaling pathway GO:0039529 7 0.010
Human
negative regulation of programmed cell death GO:0043069 321 0.010
regulation of protein stability GO:0031647 87 0.010
glycosyl compound catabolic process GO:1901658 413 0.010
mitotic cell cycle process GO:1903047 286 0.010
regulation of chromosome organization GO:0033044 103 0.010
interleukin 10 biosynthetic process GO:0042091 2 0.010

PARP12 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
cardiovascular system disease DOID:1287 106 0.012
sensory system disease DOID:0050155 203 0.011
nervous system disease DOID:863 431 0.011