Homo sapiens

11 known processes

ACLY

ATP citrate lyase

(Aliases: CLATP,ATPCL,ACL)

ACLY biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule biosynthetic process GO:0044283 157 0.897
oxidation reduction process GO:0055114 396 0.469
lipid biosynthetic process GO:0008610 177 0.438
lipid metabolic process GO:0006629 381 0.422
post embryonic development GO:0009791 2 0.357
oogenesis GO:0048477 2 0.285
vesicle mediated transport GO:0016192 371 0.235
positive regulation of developmental process GO:0051094 314 0.215
organic hydroxy compound metabolic process GO:1901615 147 0.189
determination of adult lifespan GO:0008340 2 0.168
steroid biosynthetic process GO:0006694 46 0.167
carbohydrate metabolic process GO:0005975 207 0.109
carboxylic acid biosynthetic process GO:0046394 97 0.107
multicellular organismal aging GO:0010259 3 0.104
organic hydroxy compound biosynthetic process GO:1901617 71 0.102
alcohol metabolic process GO:0006066 114 0.096
cellular amine metabolic process GO:0044106 41 0.095
single organism carbohydrate metabolic process GO:0044723 193 0.094
positive regulation of cellular component organization GO:0051130 376 0.090
oocyte differentiation GO:0009994 2 0.086
female gamete generation GO:0007292 2 0.085
regulation of cell differentiation GO:0045595 393 0.080
chemical homeostasis GO:0048878 306 0.076
steroid metabolic process GO:0008202 94 0.076
oocyte development GO:0048599 1 0.069
cellular protein complex assembly GO:0043623 188 0.069
fatty acid metabolic process GO:0006631 115 0.067
cellular lipid metabolic process GO:0044255 303 0.064
cell development GO:0048468 328 0.063
endocytosis GO:0006897 159 0.062
metal ion transport GO:0030001 272 0.059
carbohydrate derivative biosynthetic process GO:1901137 207 0.057
cytoplasmic transport GO:0016482 379 0.056
protein glycosylation GO:0006486 62 0.054
interspecies interaction between organisms GO:0044419 156 0.052
cellular amino acid metabolic process GO:0006520 116 0.050
anterior posterior axis specification GO:0009948 2 0.050
limbic system development GO:0021761 3 0.050
positive regulation of cell differentiation GO:0045597 211 0.049
cellular homeostasis GO:0019725 196 0.049
cellular macromolecular complex assembly GO:0034622 324 0.049
long chain fatty acid metabolic process GO:0001676 30 0.048
cellular ion homeostasis GO:0006873 168 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.047
amine metabolic process GO:0009308 44 0.046
microtubule cytoskeleton organization GO:0000226 176 0.046
neurotransmitter secretion GO:0007269 4 0.046
maintenance of location GO:0051235 112 0.045
response to lipid GO:0033993 206 0.045
monocarboxylic acid biosynthetic process GO:0072330 67 0.044
alcohol biosynthetic process GO:0046165 52 0.044
adult locomotory behavior GO:0008344 1 0.044
anatomical structure formation involved in morphogenesis GO:0048646 284 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
small gtpase mediated signal transduction GO:0007264 78 0.042
microtubule based process GO:0007017 210 0.041
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.041
ras protein signal transduction GO:0007265 73 0.041
monocarboxylic acid metabolic process GO:0032787 185 0.041
glycoprotein metabolic process GO:0009100 110 0.040
single organism cellular localization GO:1902580 332 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
negative regulation of protein metabolic process GO:0051248 391 0.038
locomotory behavior GO:0007626 1 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
cellular chemical homeostasis GO:0055082 180 0.037
blastoderm segmentation GO:0007350 2 0.036
segmentation GO:0035282 4 0.036
glycoprotein biosynthetic process GO:0009101 91 0.034
organic acid biosynthetic process GO:0016053 97 0.034
regulation of vesicle mediated transport GO:0060627 130 0.034
cofactor metabolic process GO:0051186 87 0.034
lipid localization GO:0010876 106 0.033
protein localization to organelle GO:0033365 280 0.033
mating GO:0007618 1 0.032
negative regulation of cellular component organization GO:0051129 235 0.032
cellular metal ion homeostasis GO:0006875 146 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
cell morphogenesis GO:0000902 296 0.030
hemopoiesis GO:0030097 180 0.030
glutamate metabolic process GO:0006536 10 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
system process GO:0003008 349 0.030
negative regulation of programmed cell death GO:0043069 321 0.029
immune system development GO:0002520 195 0.029
actin filament based process GO:0030029 224 0.028
endosomal transport GO:0016197 129 0.028
membrane organization GO:0061024 292 0.028
dendritic spine morphogenesis GO:0060997 3 0.028
actin cytoskeleton organization GO:0030036 207 0.027
protein targeting GO:0006605 187 0.027
hematopoietic or lymphoid organ development GO:0048534 186 0.027
establishment or maintenance of cell polarity GO:0007163 31 0.026
hematopoietic stem cell differentiation GO:0060218 4 0.026
glutamine family amino acid metabolic process GO:0009064 17 0.026
cellular modified amino acid biosynthetic process GO:0042398 15 0.026
tripartite regional subdivision GO:0007351 2 0.026
regulation of kinase activity GO:0043549 314 0.026
positive regulation of cell death GO:0010942 263 0.025
innate immune response GO:0045087 178 0.025
organophosphate biosynthetic process GO:0090407 163 0.024
cellular ketone metabolic process GO:0042180 80 0.024
negative regulation of multi organism process GO:0043901 92 0.024
nucleotide biosynthetic process GO:0009165 109 0.024
positive regulation of secretion GO:0051047 116 0.023
organelle localization GO:0051640 84 0.023
defense response GO:0006952 315 0.023
developmental programmed cell death GO:0010623 3 0.023
ion transmembrane transport GO:0034220 338 0.022
reproductive system development GO:0061458 56 0.022
sulfur compound metabolic process GO:0006790 101 0.022
cellular amino acid biosynthetic process GO:0008652 30 0.022
cellular cation homeostasis GO:0030003 163 0.022
ion homeostasis GO:0050801 230 0.022
nuclear migration GO:0007097 1 0.022
nucleoside phosphate biosynthetic process GO:1901293 109 0.022
positive regulation of protein polymerization GO:0032273 45 0.022
positive regulation of protein complex assembly GO:0031334 86 0.022
establishment of protein localization to organelle GO:0072594 172 0.021
single organism nuclear import GO:1902593 104 0.021
regulation of multi organism process GO:0043900 157 0.021
response to other organism GO:0051707 261 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
fatty acid biosynthetic process GO:0006633 46 0.020
response to organonitrogen compound GO:0010243 156 0.020
inner ear morphogenesis GO:0042472 4 0.020
cation homeostasis GO:0055080 189 0.020
dephosphorylation GO:0016311 209 0.020
intracellular protein transport GO:0006886 270 0.020
myeloid cell differentiation GO:0030099 117 0.020
neurogenesis GO:0022008 169 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.020
intracellular mrna localization GO:0008298 1 0.019
transmembrane transport GO:0055085 399 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
defense response to other organism GO:0098542 129 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
macromolecule glycosylation GO:0043413 63 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
establishment of organelle localization GO:0051656 59 0.018
apoptotic signaling pathway GO:0097190 268 0.018
associative learning GO:0008306 1 0.018
regulation of cell projection organization GO:0031344 107 0.018
glycosylation GO:0070085 71 0.018
viral process GO:0016032 146 0.018
organelle assembly GO:0070925 176 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
multi organism cellular process GO:0044764 156 0.018
embryo development GO:0009790 123 0.018
cell projection organization GO:0030030 252 0.017
regulation of intracellular transport GO:0032386 195 0.017
regulation of protein kinase activity GO:0045859 289 0.017
regulation of locomotion GO:0040012 329 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
regulation of cell development GO:0060284 161 0.017
regulation of endocytosis GO:0030100 72 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
metal ion homeostasis GO:0055065 169 0.017
regulation of phagocytosis engulfment GO:0060099 2 0.017
coenzyme metabolic process GO:0006732 65 0.017
tissue morphogenesis GO:0048729 96 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
response to oxygen containing compound GO:1901700 369 0.017
microtubule anchoring GO:0034453 24 0.017
synaptic transmission GO:0007268 61 0.017
neuron differentiation GO:0030182 138 0.016
trabecula morphogenesis GO:0061383 2 0.016
cation transmembrane transport GO:0098655 238 0.016
negative regulation of cell death GO:0060548 345 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
protein targeting to nucleus GO:0044744 104 0.016
response to cytokine GO:0034097 232 0.016
positive regulation of cell development GO:0010720 92 0.016
negative regulation of protein modification process GO:0031400 200 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
positive regulation of neurogenesis GO:0050769 49 0.016
neuron development GO:0048666 113 0.016
regulation of transferase activity GO:0051338 355 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.016
compound eye development GO:0048749 1 0.016
mitotic cell cycle process GO:1903047 286 0.016
regeneration GO:0031099 4 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
cellular divalent inorganic cation homeostasis GO:0072503 128 0.015
response to biotic stimulus GO:0009607 276 0.015
purine containing compound biosynthetic process GO:0072522 88 0.015
embryo development ending in birth or egg hatching GO:0009792 34 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
myosin filament assembly GO:0031034 2 0.015
synaptic vesicle endocytosis GO:0048488 2 0.015
response to abiotic stimulus GO:0009628 336 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
regulation of protein complex assembly GO:0043254 147 0.015
sterol biosynthetic process GO:0016126 10 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
alpha amino acid metabolic process GO:1901605 72 0.015
nervous system development GO:0007399 293 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
cerebral cortex cell migration GO:0021795 3 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
mitotic cell cycle GO:0000278 326 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of growth GO:0040008 165 0.014
small molecule catabolic process GO:0044282 92 0.014
response to fungus GO:0009620 4 0.014
protein polymerization GO:0051258 71 0.014
sleep GO:0030431 2 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
cellular component morphogenesis GO:0032989 314 0.014
response to external biotic stimulus GO:0043207 261 0.014
growth GO:0040007 202 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
regulation of protein transport GO:0051223 213 0.014
positive regulation of dendritic spine development GO:0060999 2 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of protein localization GO:0032880 296 0.014
negative regulation of transport GO:0051051 176 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
protein modification by small protein removal GO:0070646 92 0.013
protein import GO:0017038 130 0.013
synaptic vesicle recycling GO:0036465 3 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
neuron projection development GO:0031175 106 0.013
protein localization to nucleus GO:0034504 136 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
single organism reproductive process GO:0044702 98 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
camp biosynthetic process GO:0006171 47 0.013
maintenance of location in cell GO:0051651 62 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
demethylation GO:0070988 37 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
immune effector process GO:0002252 159 0.012
calcium ion transport GO:0006816 147 0.012
cellular response to lipid GO:0071396 127 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
reproduction GO:0000003 63 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
regulation of cellular component movement GO:0051270 334 0.012
alpha amino acid biosynthetic process GO:1901607 23 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
regulation of neurogenesis GO:0050767 82 0.012
embryonic eye morphogenesis GO:0048048 2 0.012
atp metabolic process GO:0046034 176 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
myosin filament organization GO:0031033 2 0.012
attachment of spindle microtubules to kinetochore GO:0008608 17 0.011
meiotic chromosome segregation GO:0045132 4 0.011
positive regulation of growth GO:0045927 58 0.011
sperm egg recognition GO:0035036 3 0.011
long chain fatty acid biosynthetic process GO:0042759 4 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
mitochondrion distribution GO:0048311 3 0.011
regulation of ion transport GO:0043269 189 0.011
secretion GO:0046903 254 0.011
calcium ion homeostasis GO:0055074 122 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
positive regulation of cell projection organization GO:0031346 64 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
generation of neurons GO:0048699 152 0.011
tissue homeostasis GO:0001894 63 0.011
regulation of binding GO:0051098 111 0.011
regulation of transmembrane transport GO:0034762 139 0.011
aging GO:0007568 66 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
nucleotide catabolic process GO:0009166 408 0.011
immune response GO:0006955 307 0.011
response to light stimulus GO:0009416 87 0.011
ribonucleotide biosynthetic process GO:0009260 81 0.011
hippocampus development GO:0021766 1 0.011
reproductive process GO:0022414 106 0.011
regulation of viral process GO:0050792 103 0.011
regulation of growth rate GO:0040009 1 0.010
head development GO:0060322 108 0.010
positive regulation of camp biosynthetic process GO:0030819 35 0.010
microtubule based movement GO:0007018 32 0.010
maintenance of protein location GO:0045185 57 0.010
leukocyte differentiation GO:0002521 98 0.010
negative regulation of viral process GO:0048525 66 0.010
replicative cell aging GO:0001302 3 0.010
positive regulation of immune system process GO:0002684 283 0.010
cell adhesion GO:0007155 325 0.010
detection of stimulus GO:0051606 85 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
nucleoside diphosphate metabolic process GO:0009132 16 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
cellular response to extracellular stimulus GO:0031668 72 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
neurological system process GO:0050877 163 0.010
regulation of proteolysis GO:0030162 293 0.010
protein import into nucleus GO:0006606 104 0.010

ACLY disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.047
disease of cellular proliferation DOID:14566 174 0.047
organ system cancer DOID:0050686 164 0.047
nervous system disease DOID:863 431 0.022
neuropathy DOID:870 52 0.022
disease of metabolism DOID:0014667 295 0.021
central nervous system disease DOID:331 186 0.020
disease of mental health DOID:150 70 0.014
neurodegenerative disease DOID:1289 102 0.010