|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.976
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.799
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.588
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.484
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.388
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.355
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.302
|
Fly |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.284
|
|
|
|
cellular response to laminar fluid shear stress
|
GO:0071499 |
5 |
0.278
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.270
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.249
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.243
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.232
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.227
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.225
|
Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.220
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.208
|
Human |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.206
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.199
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.197
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.196
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.191
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.179
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.169
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.155
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.150
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.140
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.139
|
Human |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.129
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.125
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.123
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.123
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.122
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.122
|
Fly |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.121
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.121
|
Human |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.118
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.117
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.111
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.110
|
Fly |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.109
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.106
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.105
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.103
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.102
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.101
|
Fly |
|
|
pharynx development
|
GO:0060465 |
1 |
0.100
|
Fly |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.097
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.097
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.097
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.096
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.093
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.091
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.088
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.087
|
Fly |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.086
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.084
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.083
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.083
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.083
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.080
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.076
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.076
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.075
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.074
|
|
|
|
head development
|
GO:0060322 |
108 |
0.074
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.073
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.073
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.072
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.070
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.069
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.068
|
|
|
|
growth
|
GO:0040007 |
202 |
0.068
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.068
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.067
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.067
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.067
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.066
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.066
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.066
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.066
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.064
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.063
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.061
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.060
|
Fly |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.060
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.060
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.059
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.059
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.059
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.058
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.058
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.057
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.057
|
Human |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.056
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.056
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.055
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.055
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.054
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.053
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.053
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.053
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.052
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.052
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.052
|
Fly |
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.052
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.052
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.051
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.051
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.051
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.051
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.050
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.050
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.050
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.050
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.049
|
Fly |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.049
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.049
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.049
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.048
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.048
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.047
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.047
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.046
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.045
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.045
|
|
|
|
cellular response to fluid shear stress
|
GO:0071498 |
7 |
0.045
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.044
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.044
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.044
|
Fly |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.044
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.044
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.043
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.043
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.043
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.043
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.042
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.042
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.042
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.042
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.042
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.041
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.041
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.040
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.040
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.040
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.040
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.040
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.039
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.039
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.039
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.039
|
Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.039
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.039
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.039
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.039
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.038
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.038
|
|
|
|
system process
|
GO:0003008 |
349 |
0.038
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.038
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.037
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.037
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.037
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.037
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.037
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.037
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.037
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.036
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.036
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.036
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.035
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.035
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.035
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.035
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.035
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.035
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.035
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.035
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.034
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.034
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.034
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.034
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.033
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.033
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.033
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.033
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.033
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.033
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.033
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.032
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.032
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.032
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.031
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.031
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.031
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.031
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.030
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.030
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.030
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.030
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.030
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.030
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.030
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.030
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.029
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.029
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.029
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.029
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.029
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.029
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.029
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.029
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.029
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.029
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.029
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.029
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.028
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.028
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.028
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.028
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.028
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.028
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.028
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.028
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.028
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.028
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.028
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.028
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.028
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.028
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.028
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.028
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.027
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.027
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.027
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.027
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.027
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.027
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.027
|
Fly |
|
|
signal release
|
GO:0023061 |
70 |
0.027
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.027
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.027
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.027
|
Fly |
|
|
cell death in response to hydrogen peroxide
|
GO:0036474 |
10 |
0.026
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.026
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.026
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.026
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.026
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.026
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.026
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.026
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.026
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.026
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.025
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.025
|
|
|
|
proteasomal ubiquitin independent protein catabolic process
|
GO:0010499 |
3 |
0.025
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.025
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.025
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.025
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.025
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.025
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.025
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.025
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.024
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.024
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.024
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.024
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.024
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.024
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.024
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.024
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.024
|
Fly |
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.024
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.024
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.024
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.023
|
Human |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.023
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.023
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.023
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.023
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.023
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.023
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.023
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.023
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.023
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.023
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.023
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.023
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.022
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
14 |
0.022
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.022
|
Fly |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.022
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.022
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.022
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.022
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.022
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.022
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.022
|
Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.022
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.021
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.021
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.021
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.021
|
Human Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.021
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.021
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.021
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.021
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.021
|
Human |
|
|
histone modification
|
GO:0016570 |
251 |
0.021
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.021
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.021
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.021
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.021
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.021
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.021
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.021
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.021
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.021
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.021
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.021
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.020
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.020
|
Human |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.020
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.020
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.020
|
Fly |
|
|
positive regulation of hemostasis
|
GO:1900048 |
11 |
0.020
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.020
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.020
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.020
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.020
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.020
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.020
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.020
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.020
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.020
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.020
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.019
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.019
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.019
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.019
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.019
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.019
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.019
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.019
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.019
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.019
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.019
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.019
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.019
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.019
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.019
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.018
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.018
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.018
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.018
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.018
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.018
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.018
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.018
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.018
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.018
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.018
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.018
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.018
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.018
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.018
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.017
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.017
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.017
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.017
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.017
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.017
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.017
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.017
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.017
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.017
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.017
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.017
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.017
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.017
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.017
|
Fly |
|
|
hormone transport
|
GO:0009914 |
68 |
0.017
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.016
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.016
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.016
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.016
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.016
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.016
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.016
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.016
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.016
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.016
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.016
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.016
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.016
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.016
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.016
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.016
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.016
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.016
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.016
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.016
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.016
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.016
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.015
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.015
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.015
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.015
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.015
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.015
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.015
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.015
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.015
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.015
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.015
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.015
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.015
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
regulation of hydrogen peroxide induced cell death
|
GO:1903205 |
10 |
0.015
|
Human |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.015
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.015
|
Fly |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.015
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.015
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.014
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.014
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.014
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.014
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.014
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.014
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.014
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.014
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.014
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.014
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.014
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.014
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.014
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.014
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.014
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.014
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.014
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.014
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.014
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.014
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.014
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.013
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.013
|
Human |
|
|
t cell activation
|
GO:0042110 |
99 |
0.013
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.013
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.013
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.013
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.013
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.013
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.013
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.013
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.013
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.013
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.013
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.013
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.013
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.013
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.013
|
Fly |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.013
|
|
