Homo sapiens

18 known processes

ANAPC1

anaphase promoting complex subunit 1

(Aliases: MCPR,APC1,TSG24)

ANAPC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein k11 linked ubiquitination GO:0070979 24 1.000
protein polyubiquitination GO:0000209 110 0.998
protein ubiquitination GO:0016567 314 0.989
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.989
regulation of sister chromatid segregation GO:0033045 27 0.987
Worm
regulation of mitotic sister chromatid separation GO:0010965 27 0.982
Worm
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.976
protein modification by small protein conjugation GO:0032446 342 0.975
regulation of mitosis GO:0007088 63 0.944
Worm
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.935
regulation of proteasomal protein catabolic process GO:0061136 87 0.847
oogenesis GO:0048477 2 0.840
regulation of nuclear division GO:0051783 65 0.827
Worm
tripartite regional subdivision GO:0007351 2 0.809
female gamete generation GO:0007292 2 0.750
mitotic cell cycle phase transition GO:0044772 162 0.682
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.654
Worm Fly
organelle fission GO:0048285 149 0.631
Worm Fly
nuclear division GO:0000280 128 0.618
Worm Fly
spindle assembly checkpoint GO:0071173 17 0.576
microtubule polymerization GO:0046785 18 0.558
negative regulation of proteolysis GO:0045861 132 0.552
regulation of cell cycle phase transition GO:1901987 126 0.552
mitotic sister chromatid segregation GO:0000070 53 0.510
Worm
regulation of cellular protein catabolic process GO:1903362 96 0.504
regulation of cell division GO:0051302 116 0.496
Worm
regulation of chromosome segregation GO:0051983 44 0.487
Worm
negative regulation of cellular protein catabolic process GO:1903363 38 0.447
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.398
Worm Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.382
post embryonic development GO:0009791 2 0.295
negative regulation of cell cycle GO:0045786 193 0.293
positive regulation of mitosis GO:0045840 25 0.289
positive regulation of protein ubiquitination GO:0031398 53 0.285
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.277
positive regulation of cellular catabolic process GO:0031331 284 0.277
blastoderm segmentation GO:0007350 2 0.261
cellular macromolecule catabolic process GO:0044265 380 0.236
Worm Fly
positive regulation of protein catabolic process GO:0045732 75 0.207
regulation of proteolysis GO:0030162 293 0.204
chromosome separation GO:0051304 23 0.192
Worm
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.192
positive regulation of cell division GO:0051781 59 0.176
determination of adult lifespan GO:0008340 2 0.173
oocyte development GO:0048599 1 0.172
negative regulation of meiotic cell cycle GO:0051447 2 0.165
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.164
cellular protein catabolic process GO:0044257 261 0.157
Worm Fly
positive regulation of chromosome organization GO:2001252 41 0.153
dna replication GO:0006260 116 0.147
dna conformation change GO:0071103 113 0.147
metaphase anaphase transition of cell cycle GO:0044784 21 0.144
Worm
hematopoietic or lymphoid organ development GO:0048534 186 0.142
regulation of protein processing GO:0070613 150 0.137
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.133
Worm
embryo development GO:0009790 123 0.133
Worm
regulation of protein catabolic process GO:0042176 155 0.124
chromosome segregation GO:0007059 114 0.121
Worm
reproductive process GO:0022414 106 0.121
regulation of mitotic cell cycle GO:0007346 189 0.121
Worm
single organism reproductive process GO:0044702 98 0.120
sister chromatid segregation GO:0000819 54 0.116
Worm
anterior posterior axis specification embryo GO:0008595 2 0.115
gonad development GO:0008406 34 0.111
sex differentiation GO:0007548 45 0.109
cellular amino acid metabolic process GO:0006520 116 0.108
protein polymerization GO:0051258 71 0.107
positive regulation of catabolic process GO:0009896 310 0.104
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.104
regulation of cell cycle GO:0051726 393 0.103
Worm
segmentation GO:0035282 4 0.098
nucleocytoplasmic transport GO:0006913 176 0.096
regulation of cell cycle process GO:0010564 266 0.095
Worm
negative regulation of catalytic activity GO:0043086 335 0.090
negative regulation of organelle organization GO:0010639 126 0.089
regulation of meiotic cell cycle GO:0051445 4 0.088
positive regulation of chromosome segregation GO:0051984 9 0.086
cell division GO:0051301 168 0.085
Worm
reproductive system development GO:0061458 56 0.081
nervous system development GO:0007399 293 0.079
Fly
regulation of dna dependent dna replication initiation GO:0030174 3 0.079
positive regulation of cell cycle GO:0045787 140 0.078
oocyte differentiation GO:0009994 2 0.076
embryo development ending in birth or egg hatching GO:0009792 34 0.074
Worm
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.071
single organism cellular localization GO:1902580 332 0.070
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.070
Worm Fly
carbohydrate derivative biosynthetic process GO:1901137 207 0.068
anterior posterior axis specification GO:0009948 2 0.067
Worm
negative regulation of cell cycle process GO:0010948 121 0.067
meiosis i GO:0007127 4 0.067
establishment of protein localization to organelle GO:0072594 172 0.067
modification dependent macromolecule catabolic process GO:0043632 212 0.064
Worm Fly
regulation of protein maturation GO:1903317 150 0.063
vesicle mediated transport GO:0016192 371 0.063
organelle assembly GO:0070925 176 0.059
nuclear transport GO:0051169 179 0.057
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.057
organophosphate catabolic process GO:0046434 430 0.057
regulation of mitotic sister chromatid segregation GO:0033047 27 0.055
Worm
dna replication initiation GO:0006270 6 0.055
regulation of cellular component movement GO:0051270 334 0.053
establishment of organelle localization GO:0051656 59 0.053
Worm
negative regulation of developmental process GO:0051093 247 0.053
positive regulation of cellular protein catabolic process GO:1903364 37 0.052
negative regulation of programmed cell death GO:0043069 321 0.051
spindle checkpoint GO:0031577 26 0.048
protein localization to organelle GO:0033365 280 0.047
negative regulation of cell death GO:0060548 345 0.046
multicellular organismal response to stress GO:0033555 1 0.045
reproductive structure development GO:0048608 55 0.045
mitotic cell cycle GO:0000278 326 0.044
Worm Fly
cardiovascular system development GO:0072358 262 0.043
cellular response to dna damage stimulus GO:0006974 379 0.042
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.041
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.041
negative regulation of protein maturation GO:1903318 142 0.040
growth GO:0040007 202 0.040
negative regulation of protein phosphorylation GO:0001933 140 0.040
development of primary sexual characteristics GO:0045137 35 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.038
regulation of meiosis GO:0040020 3 0.037
positive regulation of organelle organization GO:0010638 195 0.037
cell projection organization GO:0030030 252 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
Worm Fly
regulation of transferase activity GO:0051338 355 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.036
cytoplasmic transport GO:0016482 379 0.036
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.036
protein targeting GO:0006605 187 0.034
mitotic cell cycle process GO:1903047 286 0.034
Worm Fly
immune system development GO:0002520 195 0.033
mitotic sister chromatid separation GO:0051306 18 0.033
Worm
ribonucleotide catabolic process GO:0009261 405 0.032
protein import GO:0017038 130 0.032
maintenance of protein location in cell GO:0032507 56 0.031
multicellular organismal aging GO:0010259 3 0.031
defense response GO:0006952 315 0.031
actin filament based movement GO:0030048 17 0.030
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
microtubule cytoskeleton organization GO:0000226 176 0.030
Worm
negative regulation of hydrolase activity GO:0051346 182 0.030
regulation of nucleocytoplasmic transport GO:0046822 98 0.029
regulation of dna metabolic process GO:0051052 153 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.029
peptidyl tyrosine dephosphorylation GO:0035335 36 0.029
developmental process involved in reproduction GO:0003006 66 0.028
regulation of protein ubiquitination GO:0031396 95 0.028
cell cycle phase transition GO:0044770 173 0.027
Worm
positive regulation of nuclear division GO:0051785 27 0.027
proteasomal protein catabolic process GO:0010498 176 0.026
Worm Fly
positive regulation of cellular component organization GO:0051130 376 0.026
attachment of spindle microtubules to kinetochore GO:0008608 17 0.026
negative regulation of protein processing GO:0010955 142 0.025
reproduction GO:0000003 63 0.025
Worm
protein maturation GO:0051604 233 0.025
phospholipid metabolic process GO:0006644 99 0.025
negative regulation of sister chromatid segregation GO:0033046 17 0.025
regulation of protein localization GO:0032880 296 0.025
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.024
Worm Fly
regulation of protein targeting GO:1903533 91 0.024
rna processing GO:0006396 255 0.024
positive regulation of mitotic cell cycle GO:0045931 60 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
endocytosis GO:0006897 159 0.024
regulation of intracellular transport GO:0032386 195 0.024
single organism carbohydrate metabolic process GO:0044723 193 0.023
cellular response to organic cyclic compound GO:0071407 127 0.022
cellular response to peptide hormone stimulus GO:0071375 56 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
positive regulation of proteolysis GO:0045862 142 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
single organism nuclear import GO:1902593 104 0.022
response to acid chemical GO:0001101 66 0.022
regulation of cellular component biogenesis GO:0044087 281 0.021
regulation of cell development GO:0060284 161 0.021
carbohydrate metabolic process GO:0005975 207 0.021
mitotic metaphase plate congression GO:0007080 14 0.021
protein targeting to nucleus GO:0044744 104 0.021
pattern specification process GO:0007389 43 0.021
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
negative regulation of protein modification process GO:0031400 200 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
macromolecule glycosylation GO:0043413 63 0.020
nucleoside catabolic process GO:0009164 408 0.020
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.020
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.020
immune response GO:0006955 307 0.020
maintenance of location GO:0051235 112 0.020
protein processing GO:0016485 226 0.020
regulation of immune response GO:0050776 201 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.019
regionalization GO:0003002 29 0.019
Worm
cellular response to acid chemical GO:0071229 44 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
regulation of dendrite development GO:0050773 18 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
regulation of neurogenesis GO:0050767 82 0.017
regulation of organelle assembly GO:1902115 40 0.017
embryonic axis specification GO:0000578 5 0.017
protein glycosylation GO:0006486 62 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
cytokine production GO:0001816 247 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
cytoskeleton dependent cytokinesis GO:0061640 22 0.016
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
cellular protein complex assembly GO:0043623 188 0.016
purine nucleotide biosynthetic process GO:0006164 84 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
protein catabolic process GO:0030163 325 0.016
Worm Fly
cellular protein complex disassembly GO:0043624 36 0.016
rna phosphodiester bond hydrolysis GO:0090501 35 0.016
blastocyst development GO:0001824 3 0.016
regulation of locomotion GO:0040012 329 0.016
cellular amine metabolic process GO:0044106 41 0.016
innate immune response GO:0045087 178 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
multi organism reproductive process GO:0044703 54 0.016
response to nitrogen compound GO:1901698 184 0.016
regulation of cytoplasmic transport GO:1903649 149 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
sexual reproduction GO:0019953 37 0.015
chemical homeostasis GO:0048878 306 0.015
neuromuscular junction development GO:0007528 3 0.015
phagocytosis GO:0006909 42 0.015
positive regulation of organ growth GO:0046622 2 0.015
covalent chromatin modification GO:0016569 254 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
regulation of growth GO:0040008 165 0.015
negative regulation of endopeptidase activity GO:0010951 84 0.015
chromatin organization GO:0006325 351 0.015
cell cell signaling GO:0007267 155 0.015
cell growth GO:0016049 160 0.015
cell development GO:0048468 328 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.014
oocyte maturation GO:0001556 1 0.014
single organism membrane organization GO:0044802 268 0.014
regulation of microtubule based process GO:0032886 74 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
regulation of neuron differentiation GO:0045664 70 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
positive regulation of cytoplasmic transport GO:1903651 82 0.014
response to organophosphorus GO:0046683 41 0.014
regulation of cell differentiation GO:0045595 393 0.014
cellular component disassembly GO:0022411 92 0.014
ribonucleotide biosynthetic process GO:0009260 81 0.014
multicellular organismal reproductive process GO:0048609 40 0.014
response to organic cyclic compound GO:0014070 204 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of cell migration GO:0030334 289 0.013
negative regulation of mitotic cell cycle GO:0045930 102 0.013
generation of neurons GO:0048699 152 0.013
peptide metabolic process GO:0006518 51 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
nuclear export GO:0051168 69 0.013
immune effector process GO:0002252 159 0.013
negative regulation of cell substrate adhesion GO:0010812 24 0.013
regulation of peptidase activity GO:0052547 180 0.013
positive regulation of intracellular protein transport GO:0090316 76 0.013
cellular ketone metabolic process GO:0042180 80 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
regulation of multi organism process GO:0043900 157 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
embryonic pattern specification GO:0009880 5 0.013
hemopoiesis GO:0030097 180 0.013
circulatory system development GO:0072359 262 0.013
positive regulation of protein complex assembly GO:0031334 86 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.012
mrna export from nucleus GO:0006406 29 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
actin filament based process GO:0030029 224 0.012
protein localization to chromosome GO:0034502 30 0.012
cell adhesion GO:0007155 325 0.012
amine metabolic process GO:0009308 44 0.012
negative regulation of transferase activity GO:0051348 124 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cell activation GO:0001775 213 0.012
neuron differentiation GO:0030182 138 0.012
cellular response to growth factor stimulus GO:0071363 197 0.011
negative regulation of dendritic spine development GO:0061000 1 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of translation GO:0006417 89 0.011
dendritic spine organization GO:0097061 4 0.011
response to organonitrogen compound GO:0010243 156 0.011
protein complex disassembly GO:0043241 52 0.011
positive regulation of cytoskeleton organization GO:0051495 83 0.011
locomotory behavior GO:0007626 1 0.011
protein stabilization GO:0050821 64 0.011
response to wounding GO:0009611 168 0.011
regulation of chromosome organization GO:0033044 103 0.011
Worm
positive regulation of developmental process GO:0051094 314 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
developmental maturation GO:0021700 28 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
regulation of dna replication GO:0006275 68 0.011
phospholipid dephosphorylation GO:0046839 10 0.011
membrane organization GO:0061024 292 0.011
establishment of chromosome localization GO:0051303 20 0.011
mitochondrion organization GO:0007005 156 0.010
atp metabolic process GO:0046034 176 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
regulation of developmental growth GO:0048638 30 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
spindle organization GO:0007051 53 0.010
regulation of cell projection organization GO:0031344 107 0.010
regulation of cellular amine metabolic process GO:0033238 11 0.010

ANAPC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 52 0.028
cancer DOID:162 167 0.028
disease of cellular proliferation DOID:14566 174 0.028
organ system cancer DOID:0050686 164 0.028
central nervous system disease DOID:331 186 0.016
neurodegenerative disease DOID:1289 102 0.016
nervous system disease DOID:863 431 0.016
disease of mental health DOID:150 70 0.012