Homo sapiens

18 known processes

ANAPC5

anaphase promoting complex subunit 5

(Aliases: APC5)

ANAPC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein k11 linked ubiquitination GO:0070979 24 1.000
protein modification by small protein conjugation GO:0032446 342 0.999
protein ubiquitination GO:0016567 314 0.983
metaphase anaphase transition of cell cycle GO:0044784 21 0.978
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.977
chromosome separation GO:0051304 23 0.976
regulation of chromosome segregation GO:0051983 44 0.974
regulation of sister chromatid segregation GO:0033045 27 0.964
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.962
regulation of mitotic sister chromatid separation GO:0010965 27 0.948
protein polyubiquitination GO:0000209 110 0.921
female gamete generation GO:0007292 2 0.869
oogenesis GO:0048477 2 0.865
regulation of proteasomal protein catabolic process GO:0061136 87 0.858
cellular macromolecule catabolic process GO:0044265 380 0.858
regulation of mitosis GO:0007088 63 0.799
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.784
mitotic cell cycle phase transition GO:0044772 162 0.736
segmentation GO:0035282 4 0.724
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.721
ubiquitin dependent protein catabolic process GO:0006511 206 0.696
nuclear division GO:0000280 128 0.648
compound eye development GO:0048749 1 0.637
mitotic sister chromatid segregation GO:0000070 53 0.631
regulation of nuclear division GO:0051783 65 0.614
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.609
regulation of mitotic cell cycle phase transition GO:1901990 118 0.593
regulation of cellular protein catabolic process GO:1903362 96 0.592
negative regulation of cellular protein catabolic process GO:1903363 38 0.532
cellular protein catabolic process GO:0044257 261 0.517
organelle fission GO:0048285 149 0.499
negative regulation of cell cycle GO:0045786 193 0.477
negative regulation of proteolysis GO:0045861 132 0.467
regulation of cell cycle GO:0051726 393 0.424
anterior posterior axis specification GO:0009948 2 0.411
modification dependent macromolecule catabolic process GO:0043632 212 0.408
microtubule polymerization GO:0046785 18 0.398
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.363
regulation of cell division GO:0051302 116 0.356
presynaptic membrane assembly GO:0097105 1 0.352
modification dependent protein catabolic process GO:0019941 209 0.340
mitotic sister chromatid separation GO:0051306 18 0.328
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.326
mitotic cell cycle process GO:1903047 286 0.278
activation of anaphase promoting complex activity GO:0051488 6 0.259
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.244
chromosome segregation GO:0007059 114 0.244
positive regulation of cellular catabolic process GO:0031331 284 0.240
cell division GO:0051301 168 0.232
regulation of chromosome organization GO:0033044 103 0.215
mitotic cell cycle GO:0000278 326 0.214
cell cycle checkpoint GO:0000075 117 0.210
regulation of cell cycle process GO:0010564 266 0.208
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.196
pattern specification process GO:0007389 43 0.195
embryo development GO:0009790 123 0.176
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.173
sister chromatid segregation GO:0000819 54 0.172
reproductive system development GO:0061458 56 0.170
single organism reproductive process GO:0044702 98 0.170
developmental process involved in reproduction GO:0003006 66 0.169
reproductive structure development GO:0048608 55 0.164
negative regulation of dendritic spine development GO:0061000 1 0.162
dna integrity checkpoint GO:0031570 71 0.162
post embryonic development GO:0009791 2 0.160
mitotic nuclear division GO:0007067 119 0.157
anterior posterior axis specification embryo GO:0008595 2 0.157
negative regulation of cell cycle process GO:0010948 121 0.151
positive regulation of chromosome segregation GO:0051984 9 0.148
organophosphate catabolic process GO:0046434 430 0.148
positive regulation of chromosome organization GO:2001252 41 0.146
cell cycle phase transition GO:0044770 173 0.146
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.146
regulation of mitotic cell cycle GO:0007346 189 0.145
microtubule cytoskeleton organization GO:0000226 176 0.145
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.144
proteasomal protein catabolic process GO:0010498 176 0.143
regionalization GO:0003002 29 0.140
nervous system development GO:0007399 293 0.140
regulation of protein processing GO:0070613 150 0.133
neuron differentiation GO:0030182 138 0.133
regulation of mitotic sister chromatid segregation GO:0033047 27 0.130
regulation of dna dependent dna replication initiation GO:0030174 3 0.127
negative regulation of developmental process GO:0051093 247 0.125
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.124
blastoderm segmentation GO:0007350 2 0.121
regulation of protein catabolic process GO:0042176 155 0.119
regulation of proteolysis GO:0030162 293 0.119
mitotic metaphase plate congression GO:0007080 14 0.118
positive regulation of protein ubiquitination GO:0031398 53 0.117
oocyte development GO:0048599 1 0.116
neurogenesis GO:0022008 169 0.113
regulation of cell cycle phase transition GO:1901987 126 0.111
protein catabolic process GO:0030163 325 0.110
sensory organ development GO:0007423 52 0.109
regulation of meiotic cell cycle GO:0051445 4 0.106
ribose phosphate biosynthetic process GO:0046390 82 0.105
microtubule based process GO:0007017 210 0.101
oocyte differentiation GO:0009994 2 0.093
cell development GO:0048468 328 0.093
organonitrogen compound biosynthetic process GO:1901566 200 0.093
covalent chromatin modification GO:0016569 254 0.087
meiotic nuclear division GO:0007126 10 0.086
negative regulation of meiotic cell cycle GO:0051447 2 0.085
tripartite regional subdivision GO:0007351 2 0.084
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.083
regulation of protein maturation GO:1903317 150 0.081
vesicle mediated transport GO:0016192 371 0.079
specification of axis polarity GO:0065001 1 0.077
positive regulation of catabolic process GO:0009896 310 0.076
cytoskeleton dependent cytokinesis GO:0061640 22 0.075
mitotic spindle checkpoint GO:0071174 18 0.074
negative regulation of organelle organization GO:0010639 126 0.074
negative regulation of cellular catabolic process GO:0031330 83 0.072
negative regulation of catalytic activity GO:0043086 335 0.069
endocytosis GO:0006897 159 0.067
positive regulation of protein catabolic process GO:0045732 75 0.067
dna replication GO:0006260 116 0.066
protein dephosphorylation GO:0006470 81 0.064
positive regulation of nuclear division GO:0051785 27 0.062
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.061
meiosis i GO:0007127 4 0.061
positive regulation of mitosis GO:0045840 25 0.061
embryo development ending in birth or egg hatching GO:0009792 34 0.060
Worm
protein polymerization GO:0051258 71 0.059
cellular amino acid metabolic process GO:0006520 116 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.058
cellular protein complex assembly GO:0043623 188 0.057
multicellular organismal aging GO:0010259 3 0.055
protein glycosylation GO:0006486 62 0.055
reproductive process GO:0022414 106 0.055
protein localization to organelle GO:0033365 280 0.053
negative regulation of cell differentiation GO:0045596 171 0.052
purine ribonucleotide catabolic process GO:0009154 404 0.052
meiotic cell cycle checkpoint GO:0033313 1 0.052
negative regulation of programmed cell death GO:0043069 321 0.051
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.051
regulation of nucleotide metabolic process GO:0006140 269 0.050
negative regulation of protein modification process GO:0031400 200 0.047
determination of adult lifespan GO:0008340 2 0.045
organelle assembly GO:0070925 176 0.045
cell projection morphogenesis GO:0048858 129 0.045
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.045
negative regulation of sister chromatid segregation GO:0033046 17 0.045
negative regulation of protein phosphorylation GO:0001933 140 0.043
endomembrane system organization GO:0010256 196 0.043
spindle checkpoint GO:0031577 26 0.043
purine ribonucleoside metabolic process GO:0046128 437 0.042
reproduction GO:0000003 63 0.040
ribonucleoside catabolic process GO:0042454 406 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.039
development of primary sexual characteristics GO:0045137 35 0.039
regulation of transferase activity GO:0051338 355 0.039
cell cell signaling GO:0007267 155 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.039
single organism cellular localization GO:1902580 332 0.038
amine metabolic process GO:0009308 44 0.038
negative regulation of phosphorylation GO:0042326 174 0.037
posttranscriptional regulation of gene expression GO:0010608 213 0.037
mitotic cytokinesis GO:0000281 19 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.036
positive regulation of cell cycle GO:0045787 140 0.035
carbohydrate metabolic process GO:0005975 207 0.034
nucleoside catabolic process GO:0009164 408 0.034
macromolecule glycosylation GO:0043413 63 0.034
neuron projection development GO:0031175 106 0.034
locomotory behavior GO:0007626 1 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
protein localization to nucleus GO:0034504 136 0.032
regulation of protein localization to nucleus GO:1900180 85 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
negative regulation of protein metabolic process GO:0051248 391 0.030
protein maturation GO:0051604 233 0.030
translation GO:0006412 132 0.030
regulation of meiosis GO:0040020 3 0.030
sex differentiation GO:0007548 45 0.030
glycosylation GO:0070085 71 0.029
axis specification GO:0009798 12 0.029
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.029
methylation GO:0032259 106 0.029
organelle localization GO:0051640 84 0.028
cellular component disassembly GO:0022411 92 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
cardiovascular system development GO:0072358 262 0.028
negative regulation of protein maturation GO:1903318 142 0.028
meiotic chromosome segregation GO:0045132 4 0.027
mitotic cell cycle checkpoint GO:0007093 68 0.026
positive regulation of developmental process GO:0051094 314 0.026
nuclear transport GO:0051169 179 0.026
synaptic transmission GO:0007268 61 0.026
negative regulation of mitotic cell cycle GO:0045930 102 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
multicellular organismal reproductive process GO:0048609 40 0.025
protein processing GO:0016485 226 0.025
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.025
gtp metabolic process GO:0046039 239 0.025
regeneration GO:0031099 4 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
negative regulation of cellular component organization GO:0051129 235 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.024
gonad development GO:0008406 34 0.024
generation of neurons GO:0048699 152 0.024
small molecule catabolic process GO:0044282 92 0.024
oligodendrocyte differentiation GO:0048709 7 0.023
ribonucleotide biosynthetic process GO:0009260 81 0.023
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.023
neuromuscular junction development GO:0007528 3 0.023
regulation of protein localization GO:0032880 296 0.022
establishment of organelle localization GO:0051656 59 0.022
rna processing GO:0006396 255 0.022
multi organism reproductive process GO:0044703 54 0.022
cellular amine metabolic process GO:0044106 41 0.022
mitochondrion organization GO:0007005 156 0.022
dna conformation change GO:0071103 113 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
cellular carbohydrate metabolic process GO:0044262 84 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
regulation of growth GO:0040008 165 0.021
neurological system process GO:0050877 163 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.021
mitotic dna integrity checkpoint GO:0044774 30 0.021
response to abiotic stimulus GO:0009628 336 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.020
regulation of kinase activity GO:0043549 314 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
establishment of spindle localization GO:0051293 12 0.020
cellular component morphogenesis GO:0032989 314 0.020
cytoplasmic transport GO:0016482 379 0.020
purine nucleotide biosynthetic process GO:0006164 84 0.020
regulation of feeding behavior GO:0060259 3 0.020
sexual reproduction GO:0019953 37 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
immune effector process GO:0002252 159 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
presynaptic membrane organization GO:0097090 3 0.018
cell adhesion GO:0007155 325 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of protein kinase activity GO:0045859 289 0.018
embryonic axis specification GO:0000578 5 0.018
interspecies interaction between organisms GO:0044419 156 0.018
negative regulation of kinase activity GO:0033673 106 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
anterior posterior pattern specification GO:0009952 9 0.017
positive regulation of organelle organization GO:0010638 195 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
purine containing compound catabolic process GO:0072523 411 0.017
actin filament based process GO:0030029 224 0.017
regulation of nucleocytoplasmic transport GO:0046822 98 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
negative regulation of response to external stimulus GO:0032102 83 0.017
chromatin organization GO:0006325 351 0.017
cell projection organization GO:0030030 252 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
response to biotic stimulus GO:0009607 276 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
negative regulation of excitatory postsynaptic membrane potential GO:0090394 1 0.016
phospholipid dephosphorylation GO:0046839 10 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.016
regulation of cell differentiation GO:0045595 393 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
negative regulation of growth GO:0045926 97 0.015
negative regulation of transferase activity GO:0051348 124 0.015
negative regulation of myelination GO:0031642 1 0.015
response to organic cyclic compound GO:0014070 204 0.015
regulation of multi organism process GO:0043900 157 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
phagocytosis GO:0006909 42 0.015
negative regulation of protein processing GO:0010955 142 0.015
eye development GO:0001654 42 0.015
oligodendrocyte development GO:0014003 6 0.015
multi organism cellular process GO:0044764 156 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
growth GO:0040007 202 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
circulatory system development GO:0072359 262 0.015
cellular ketone metabolic process GO:0042180 80 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
gamete generation GO:0007276 25 0.015
regulation of gtpase activity GO:0043087 180 0.015
nucleotide catabolic process GO:0009166 408 0.015
neuron development GO:0048666 113 0.015
glycoprotein metabolic process GO:0009100 110 0.014
system process GO:0003008 349 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.014
hemopoiesis GO:0030097 180 0.014
inositol phosphate dephosphorylation GO:0046855 4 0.014
eye photoreceptor cell differentiation GO:0001754 2 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
protein targeting to nucleus GO:0044744 104 0.014
central nervous system myelination GO:0022010 1 0.014
alpha amino acid metabolic process GO:1901605 72 0.013
rna modification GO:0009451 27 0.013
macromolecular complex disassembly GO:0032984 60 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
viral process GO:0016032 146 0.013
membrane organization GO:0061024 292 0.013
phospholipid metabolic process GO:0006644 99 0.013
gtp catabolic process GO:0006184 237 0.013
maintenance of location in cell GO:0051651 62 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
regulation of dendrite development GO:0050773 18 0.013
purine ribonucleotide biosynthetic process GO:0009152 79 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
positive regulation of immune response GO:0050778 159 0.012
central nervous system neuron axonogenesis GO:0021955 3 0.012
adult locomotory behavior GO:0008344 1 0.012
dendritic spine organization GO:0097061 4 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
spindle organization GO:0007051 53 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
regulation of mrna processing GO:0050684 48 0.012
defense response GO:0006952 315 0.012
regulation of microtubule based process GO:0032886 74 0.012
convergent extension GO:0060026 1 0.012
cell morphogenesis GO:0000902 296 0.012
negative regulation of catabolic process GO:0009895 104 0.012
regulation of membrane potential GO:0042391 95 0.012
dendrite development GO:0016358 24 0.011
nucleic acid transport GO:0050657 39 0.011
cell part morphogenesis GO:0032990 137 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
response to metal ion GO:0010038 84 0.011
regulation of response to external stimulus GO:0032101 222 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.011
maintenance of protein location in cell GO:0032507 56 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
stem cell differentiation GO:0048863 93 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
cellular amide metabolic process GO:0043603 69 0.011
regulation of translation GO:0006417 89 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
regulation of intracellular transport GO:0032386 195 0.011
establishment of meiotic spindle localization GO:0051295 2 0.011
protein stabilization GO:0050821 64 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
single organism membrane organization GO:0044802 268 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
spindle assembly checkpoint GO:0071173 17 0.010
meiotic cell cycle process GO:1903046 8 0.010
negative regulation of cell death GO:0060548 345 0.010
transmission of nerve impulse GO:0019226 11 0.010
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.010
ribonucleoside biosynthetic process GO:0042455 25 0.010
single organism nuclear import GO:1902593 104 0.010

ANAPC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.106
inherited metabolic disorder DOID:655 242 0.106
central nervous system disease DOID:331 186 0.020
neurodegenerative disease DOID:1289 102 0.020
nervous system disease DOID:863 431 0.020
sensory system disease DOID:0050155 203 0.019
gastrointestinal system cancer DOID:3119 52 0.015
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
carbohydrate metabolic disorder DOID:2978 55 0.011
congenital disorder of glycosylation DOID:5212 26 0.011