Homo sapiens

41 known processes

PSMD11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

(Aliases: MGC3844,S9,p44.5,Rpn6)

PSMD11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.997
regulation of peptidase activity GO:0052547 180 0.992
regulation of cell cycle GO:0051726 393 0.987
determination of adult lifespan GO:0008340 2 0.978
Worm
modification dependent protein catabolic process GO:0019941 209 0.976
proteasomal protein catabolic process GO:0010498 176 0.973
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.972
positive regulation of peptidase activity GO:0010952 88 0.972
protein catabolic process GO:0030163 325 0.967
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.966
proteasome regulatory particle assembly GO:0070682 2 0.953
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.949
post embryonic development GO:0009791 2 0.949
Worm
maintenance of location in cell GO:0051651 62 0.943
regulation of endopeptidase activity GO:0052548 170 0.942
ubiquitin dependent protein catabolic process GO:0006511 206 0.932
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.880
regulation of proteolysis GO:0030162 293 0.866
multicellular organismal aging GO:0010259 3 0.860
Worm
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.853
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.843
positive regulation of endopeptidase activity GO:0010950 84 0.833
positive regulation of proteolysis GO:0045862 142 0.831
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.827
blastocyst development GO:0001824 3 0.810
maintenance of protein location in cell GO:0032507 56 0.809
mitotic spindle elongation GO:0000022 4 0.784
modification dependent macromolecule catabolic process GO:0043632 212 0.772
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.771
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.771
regulation of proteasomal protein catabolic process GO:0061136 87 0.768
proteasome assembly GO:0043248 7 0.740
positive regulation of protein catabolic process GO:0045732 75 0.729
oogenesis GO:0048477 2 0.699
cellular protein catabolic process GO:0044257 261 0.698
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.689
nucleoside phosphate catabolic process GO:1901292 412 0.688
intracellular protein transport GO:0006886 270 0.675
negative regulation of peptidase activity GO:0010466 91 0.665
response to radiation GO:0009314 151 0.619
mitotic cell cycle process GO:1903047 286 0.612
cellular response to dna damage stimulus GO:0006974 379 0.588
response to growth factor GO:0070848 205 0.573
mitotic cell cycle GO:0000278 326 0.563
spindle elongation GO:0051231 4 0.549
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.538
dna repair GO:0006281 198 0.533
positive regulation of cellular protein catabolic process GO:1903364 37 0.530
negative regulation of endopeptidase activity GO:0010951 84 0.520
i kappab kinase nf kappab signaling GO:0007249 166 0.518
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.480
nervous system development GO:0007399 293 0.479
regulation of mitotic cell cycle GO:0007346 189 0.457
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.449
protein modification by small protein conjugation GO:0032446 342 0.446
nucleotide excision repair GO:0006289 31 0.416
regulation of cell cycle process GO:0010564 266 0.409
negative regulation of phosphorylation GO:0042326 174 0.394
regulation of cellular protein catabolic process GO:1903362 96 0.368
cellular component morphogenesis GO:0032989 314 0.354
protein modification by small protein removal GO:0070646 92 0.319
regulation of cellular response to stress GO:0080135 244 0.315
maintenance of protein location GO:0045185 57 0.310
negative regulation of proteolysis GO:0045861 132 0.306
microtubule cytoskeleton organization GO:0000226 176 0.280
immune response GO:0006955 307 0.277
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.276
cell morphogenesis GO:0000902 296 0.275
mapk cascade GO:0000165 288 0.274
regulation of protein complex assembly GO:0043254 147 0.271
negative regulation of catalytic activity GO:0043086 335 0.270
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.267
purine nucleoside triphosphate catabolic process GO:0009146 392 0.262
nuclear transport GO:0051169 179 0.257
embryo development GO:0009790 123 0.256
Worm
defense response GO:0006952 315 0.245
neurogenesis GO:0022008 169 0.235
negative regulation of apoptotic process GO:0043066 316 0.229
response to external biotic stimulus GO:0043207 261 0.217
negative regulation of phosphate metabolic process GO:0045936 267 0.211
negative regulation of cell death GO:0060548 345 0.210
regulation of transcription factor import into nucleus GO:0042990 39 0.208
cellular macromolecular complex assembly GO:0034622 324 0.204
regulation of protein processing GO:0070613 150 0.202
negative regulation of protein processing GO:0010955 142 0.202
negative regulation of cell proliferation GO:0008285 228 0.202
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.201
purine containing compound catabolic process GO:0072523 411 0.199
negative regulation of protein maturation GO:1903318 142 0.198
cell morphogenesis involved in differentiation GO:0000904 144 0.193
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.192
positive regulation of protein complex assembly GO:0031334 86 0.192
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.179
protein targeting GO:0006605 187 0.174
cellular response to endogenous stimulus GO:0071495 336 0.161
purine ribonucleoside metabolic process GO:0046128 437 0.160
purine nucleotide catabolic process GO:0006195 405 0.158
single organism cellular localization GO:1902580 332 0.157
negative regulation of cellular protein metabolic process GO:0032269 353 0.157
negative regulation of cell cycle GO:0045786 193 0.155
microtubule based process GO:0007017 210 0.153
amide transport GO:0042886 76 0.153
mitochondrion organization GO:0007005 156 0.153
aging GO:0007568 66 0.148
Worm
establishment of protein localization to organelle GO:0072594 172 0.145
maintenance of location GO:0051235 112 0.143
negative regulation of programmed cell death GO:0043069 321 0.141
protein dna complex subunit organization GO:0071824 80 0.136
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.135
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.132
purine ribonucleotide catabolic process GO:0009154 404 0.132
ribonucleotide catabolic process GO:0009261 405 0.131
meiotic chromosome segregation GO:0045132 4 0.127
regulation of protein localization GO:0032880 296 0.125
protein localization to organelle GO:0033365 280 0.121
negative regulation of multicellular organismal process GO:0051241 317 0.119
chromatin organization GO:0006325 351 0.118
protein dna complex assembly GO:0065004 64 0.117
purine nucleoside catabolic process GO:0006152 398 0.117
regulation of protein transport GO:0051223 213 0.114
regulation of locomotion GO:0040012 329 0.113
protein maturation GO:0051604 233 0.111
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.110
nuclear division GO:0000280 128 0.110
regulation of protein maturation GO:1903317 150 0.108
protein processing GO:0016485 226 0.106
positive regulation of cellular catabolic process GO:0031331 284 0.102
regulation of transferase activity GO:0051338 355 0.102
regulation of kinase activity GO:0043549 314 0.100
negative regulation of catabolic process GO:0009895 104 0.099
negative regulation of protein metabolic process GO:0051248 391 0.096
regulation of protein ubiquitination GO:0031396 95 0.096
negative regulation of developmental process GO:0051093 247 0.092
negative regulation of phosphorus metabolic process GO:0010563 267 0.092
neuromuscular junction development GO:0007528 3 0.092
regulation of cell growth GO:0001558 135 0.089
regulation of protein import into nucleus GO:0042306 78 0.088
response to transforming growth factor beta GO:0071559 94 0.088
cell division GO:0051301 168 0.088
cellular response to radiation GO:0071478 65 0.087
chromosome segregation GO:0007059 114 0.087
regulation of growth GO:0040008 165 0.087
response to abiotic stimulus GO:0009628 336 0.087
neuron projection morphogenesis GO:0048812 50 0.087
ossification GO:0001503 121 0.086
reproduction GO:0000003 63 0.086
Worm
nucleoside monophosphate metabolic process GO:0009123 191 0.085
regulation of cellular component biogenesis GO:0044087 281 0.084
signal transduction by phosphorylation GO:0023014 297 0.083
organ morphogenesis GO:0009887 147 0.080
response to biotic stimulus GO:0009607 276 0.080
enzyme linked receptor protein signaling pathway GO:0007167 303 0.077
negative regulation of protein import into nucleus GO:0042308 30 0.077
rna interference GO:0016246 4 0.075
multi organism cellular process GO:0044764 156 0.074
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.074
glycosyl compound catabolic process GO:1901658 413 0.074
positive regulation of cellular component organization GO:0051130 376 0.072
regulation of cell morphogenesis GO:0022604 153 0.071
multicellular organism reproduction GO:0032504 42 0.070
nucleotide catabolic process GO:0009166 408 0.070
neuron development GO:0048666 113 0.069
response to other organism GO:0051707 261 0.069
negative regulation of cell cycle process GO:0010948 121 0.069
cell part morphogenesis GO:0032990 137 0.068
positive regulation of hydrolase activity GO:0051345 331 0.068
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.067
cytoplasmic transport GO:0016482 379 0.066
dna damage checkpoint GO:0000077 68 0.066
organelle fission GO:0048285 149 0.065
regulation of intracellular transport GO:0032386 195 0.064
regulation of dna templated transcription initiation GO:2000142 9 0.064
negative regulation of cell differentiation GO:0045596 171 0.063
positive regulation of cellular component biogenesis GO:0044089 158 0.063
regulation of multi organism process GO:0043900 157 0.063
negative regulation of protein modification process GO:0031400 200 0.062
negative regulation of transport GO:0051051 176 0.062
epithelial to mesenchymal transition GO:0001837 48 0.061
rna catabolic process GO:0006401 71 0.061
regulation of cytoplasmic transport GO:1903649 149 0.060
regulation of cell migration GO:0030334 289 0.060
regulation of protein catabolic process GO:0042176 155 0.060
female gamete generation GO:0007292 2 0.057
cell cell signaling GO:0007267 155 0.056
chromatin modification GO:0016568 298 0.055
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
positive regulation of apoptotic process GO:0043065 246 0.054
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.054
taxis GO:0042330 157 0.054
regulation of mapk cascade GO:0043408 262 0.052
regulation of cell division GO:0051302 116 0.052
nucleoside triphosphate metabolic process GO:0009141 422 0.051
nucleoside catabolic process GO:0009164 408 0.051
purine nucleoside monophosphate catabolic process GO:0009128 158 0.051
synaptic transmission GO:0007268 61 0.050
positive regulation of intracellular protein transport GO:0090316 76 0.050
protein deubiquitination GO:0016579 79 0.050
potassium ion transmembrane transport GO:0071805 60 0.050
nuclear import GO:0051170 106 0.050
negative regulation of protein transport GO:0051224 75 0.049
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.048
cellular protein complex assembly GO:0043623 188 0.048
regulation of anatomical structure morphogenesis GO:0022603 286 0.047
embryo development ending in birth or egg hatching GO:0009792 34 0.046
Worm
atp metabolic process GO:0046034 176 0.046
nucleocytoplasmic transport GO:0006913 176 0.045
cell projection organization GO:0030030 252 0.045
regulation of protein serine threonine kinase activity GO:0071900 179 0.045
locomotory behavior GO:0007626 1 0.045
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.044
positive regulation of growth GO:0045927 58 0.044
positive regulation of transcription factor import into nucleus GO:0042993 25 0.044
segmentation GO:0035282 4 0.044
apoptotic signaling pathway GO:0097190 268 0.043
protein ubiquitination GO:0016567 314 0.043
neuron differentiation GO:0030182 138 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.042
spermatid differentiation GO:0048515 4 0.042
regulation of response to external stimulus GO:0032101 222 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.040
negative regulation of hydrolase activity GO:0051346 182 0.040
dna templated transcription initiation GO:0006352 35 0.040
response to uv GO:0009411 73 0.040
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.039
positive regulation of cell death GO:0010942 263 0.039
regulation of cysteine type endopeptidase activity GO:2000116 127 0.039
negative regulation of mitotic cell cycle GO:0045930 102 0.039
positive regulation of protein ubiquitination GO:0031398 53 0.038
regulation of mrna export from nucleus GO:0010793 3 0.038
epithelium development GO:0060429 227 0.038
viral process GO:0016032 146 0.038
regulation of stem cell differentiation GO:2000736 56 0.037
regulation of protein targeting GO:1903533 91 0.037
mitotic nuclear division GO:0007067 119 0.036
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.036
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.036
system process GO:0003008 349 0.036
angiogenesis GO:0001525 147 0.035
innate immune response GO:0045087 178 0.035
regulation of establishment of protein localization GO:0070201 242 0.034
nucleoside triphosphate catabolic process GO:0009143 394 0.034
retinal ganglion cell axon guidance GO:0031290 2 0.034
negative regulation of cell cycle phase transition GO:1901988 89 0.034
regulation of behavior GO:0050795 82 0.034
mitochondrial fission GO:0000266 14 0.033
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.033
negative regulation of intracellular signal transduction GO:1902532 183 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.033
eye development GO:0001654 42 0.033
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.032
regulation of defense response GO:0031347 154 0.032
cell proliferation involved in heart valve development GO:2000793 1 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
protein import GO:0017038 130 0.031
negative regulation of cell migration GO:0030336 102 0.031
mitotic cell cycle phase transition GO:0044772 162 0.031
autophagy GO:0006914 88 0.031
protein deneddylation GO:0000338 10 0.030
regulation of protein localization to nucleus GO:1900180 85 0.030
response to virus GO:0009615 126 0.030
protein targeting to nucleus GO:0044744 104 0.030
cell projection morphogenesis GO:0048858 129 0.030
response to drug GO:0042493 81 0.030
organic acid biosynthetic process GO:0016053 97 0.030
posttranscriptional regulation of gene expression GO:0010608 213 0.029
protein k63 linked deubiquitination GO:0070536 21 0.029
chemotaxis GO:0006935 157 0.029
negative regulation of defense response GO:0031348 47 0.028
positive regulation of dna templated transcription initiation GO:2000144 5 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
cell growth GO:0016049 160 0.028
transcription factor import into nucleus GO:0042991 40 0.027
regulation of mitotic cell cycle phase transition GO:1901990 118 0.027
regulation of immune response GO:0050776 201 0.026
cell development GO:0048468 328 0.026
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.026
response to light stimulus GO:0009416 87 0.026
epithelial cell migration GO:0010631 119 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
cell cycle phase transition GO:0044770 173 0.025
regulation of cell cycle phase transition GO:1901987 126 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.025
cellular amine metabolic process GO:0044106 41 0.024
cell cycle checkpoint GO:0000075 117 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
protein deglycosylation GO:0006517 2 0.024
regulation of response to dna damage stimulus GO:2001020 94 0.024
negative regulation of cellular component organization GO:0051129 235 0.023
positive regulation of intracellular transport GO:0032388 104 0.023
renal system development GO:0072001 63 0.023
growth GO:0040007 202 0.023
response to alcohol GO:0097305 64 0.023
regulation of jnk cascade GO:0046328 73 0.023
spermatid development GO:0007286 4 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.023
positive regulation of cell cycle GO:0045787 140 0.023
regulation of binding GO:0051098 111 0.023
ncrna metabolic process GO:0034660 108 0.022
negative regulation of mapk cascade GO:0043409 56 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.022
negative regulation of cellular catabolic process GO:0031330 83 0.021
regulation of intracellular protein transport GO:0033157 123 0.021
protein polyubiquitination GO:0000209 110 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
bmp signaling pathway GO:0030509 49 0.021
apoptotic mitochondrial changes GO:0008637 57 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
recombinational repair GO:0000725 50 0.020
single organism nuclear import GO:1902593 104 0.020
camera type eye development GO:0043010 25 0.020
response to hormone GO:0009725 175 0.020
chromatin assembly or disassembly GO:0006333 78 0.020
axonogenesis GO:0007409 31 0.020
immune effector process GO:0002252 159 0.020
reproductive structure development GO:0048608 55 0.020
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
protein secretion GO:0009306 98 0.019
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
dna integrity checkpoint GO:0031570 71 0.018
mesenchymal cell development GO:0014031 50 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
pathway restricted smad protein phosphorylation GO:0060389 38 0.018
regulation of cell development GO:0060284 161 0.018
protein localization to nucleus GO:0034504 136 0.018
secretion by cell GO:0032940 226 0.018
sensory organ development GO:0007423 52 0.018
chromatin remodeling GO:0006338 55 0.018
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.018
organophosphate catabolic process GO:0046434 430 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
cellular potassium ion transport GO:0071804 60 0.017
regulation of bmp signaling pathway GO:0030510 27 0.017
extrinsic apoptotic signaling pathway GO:0097191 119 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
cellular ketone metabolic process GO:0042180 80 0.017
oocyte development GO:0048599 1 0.017
regulation of cell cycle g1 s phase transition GO:1902806 42 0.017
positive regulation of transferase activity GO:0051347 227 0.017
amine metabolic process GO:0009308 44 0.016
single organism cell adhesion GO:0098602 179 0.016
single organism reproductive process GO:0044702 98 0.016
positive regulation of catabolic process GO:0009896 310 0.016
biological adhesion GO:0022610 331 0.016
mitotic dna integrity checkpoint GO:0044774 30 0.016
embryonic organ development GO:0048568 36 0.016
histone modification GO:0016570 251 0.016
regulation of protein kinase activity GO:0045859 289 0.015
response to organic cyclic compound GO:0014070 204 0.015
blood vessel development GO:0001568 172 0.015
blastoderm segmentation GO:0007350 2 0.015
potassium ion transport GO:0006813 62 0.015
defense response to other organism GO:0098542 129 0.015
negative regulation of response to external stimulus GO:0032102 83 0.015
monoubiquitinated histone deubiquitination GO:0035521 3 0.015
double strand break repair via nonhomologous end joining GO:0006303 10 0.015
cell junction organization GO:0034330 79 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
double strand break repair GO:0006302 101 0.014
myoblast fusion GO:0007520 1 0.014
regulation of ketone biosynthetic process GO:0010566 7 0.014
response to oxygen containing compound GO:1901700 369 0.014
osteoblast differentiation GO:0001649 92 0.014
neuron projection guidance GO:0097485 12 0.014
nucleosome organization GO:0034728 66 0.014
isoprenoid metabolic process GO:0006720 39 0.014
negative regulation of cell motility GO:2000146 104 0.014
epithelial cell differentiation GO:0030855 141 0.014
stress activated mapk cascade GO:0051403 93 0.014
response to ionizing radiation GO:0010212 65 0.013
dephosphorylation GO:0016311 209 0.013
brain morphogenesis GO:0048854 1 0.013
small molecule biosynthetic process GO:0044283 157 0.013
zymogen activation GO:0031638 70 0.013
neuroblast proliferation GO:0007405 4 0.013
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.013
vesicle mediated transport GO:0016192 371 0.013
cardiovascular system development GO:0072358 262 0.013
peptidyl tyrosine dephosphorylation GO:0035335 36 0.013
regulation of potassium ion transmembrane transport GO:1901379 20 0.013
axon development GO:0061564 34 0.013
regulation of transmembrane transport GO:0034762 139 0.013
negative regulation of intracellular protein transport GO:0090317 42 0.013
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.012
negative regulation of response to dna damage stimulus GO:2001021 33 0.012
lipid metabolic process GO:0006629 381 0.012
non recombinational repair GO:0000726 14 0.012
regulation of nf kappab import into nucleus GO:0042345 22 0.012
hard palate development GO:0060022 1 0.012
regulation of epithelial to mesenchymal transition GO:0010717 37 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.012
cellular response to hormone stimulus GO:0032870 125 0.011
negative regulation of growth GO:0045926 97 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
dna conformation change GO:0071103 113 0.011
body morphogenesis GO:0010171 11 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
formation of primary germ layer GO:0001704 42 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
response to wounding GO:0009611 168 0.011
reproductive process GO:0022414 106 0.011
lipid biosynthetic process GO:0008610 177 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
progesterone receptor signaling pathway GO:0050847 3 0.010
vacuolar transport GO:0007034 34 0.010
actin mediated cell contraction GO:0070252 12 0.010
cellular response to abiotic stimulus GO:0071214 117 0.010
behavior GO:0007610 112 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010

PSMD11 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.022
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.021