Homo sapiens

70 known processes

HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

(Aliases: HLA-DP1A,HLASB,HLADP,PLT1)

HLA-DPA1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 1.000
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.998
peptide antigen assembly with mhc protein complex GO:0002501 4 0.994
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.985
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.985
negative regulation of antigen processing and presentation GO:0002578 5 0.983
antigen processing and presentation GO:0019882 33 0.972
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 0.960
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.927
antigen processing and presentation of peptide antigen GO:0048002 18 0.915
regulation of t cell proliferation GO:0042129 42 0.899
de novo protein folding GO:0006458 2 0.896
lymphocyte proliferation GO:0046651 70 0.891
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.886
cytokine production GO:0001816 247 0.866
mhc class ii protein complex assembly GO:0002399 4 0.847
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002581 3 0.846
regulation of lymphocyte proliferation GO:0050670 64 0.835
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.823
cell activation GO:0001775 213 0.794
negative regulation of immune system process GO:0002683 136 0.739
regulation of interleukin 10 secretion GO:2001179 4 0.730
regulation of mononuclear cell proliferation GO:0032944 65 0.720
regulation of leukocyte activation GO:0002694 115 0.710
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002580 4 0.710
leukocyte activation GO:0045321 164 0.709
mononuclear cell proliferation GO:0032943 71 0.689
negative regulation of response to external stimulus GO:0032102 83 0.680
t cell activation GO:0042110 99 0.678
cellular protein complex assembly GO:0043623 188 0.659
regulation of dendritic cell antigen processing and presentation GO:0002604 1 0.651
positive regulation of lymphocyte proliferation GO:0050671 46 0.647
positive regulation of lymphocyte activation GO:0051251 73 0.605
positive regulation of lymphocyte differentiation GO:0045621 13 0.586
lymphocyte activation GO:0046649 133 0.584
leukocyte proliferation GO:0070661 74 0.577
regulation of lymphocyte activation GO:0051249 103 0.565
negative regulation of cell proliferation GO:0008285 228 0.564
regulation of cell activation GO:0050865 125 0.564
regulation of leukocyte proliferation GO:0070663 67 0.563
peptide secretion GO:0002790 51 0.563
cellular lipid metabolic process GO:0044255 303 0.533
lymphocyte mediated immunity GO:0002449 48 0.521
protein carbohydrate complex subunit organization GO:0071823 2 0.514
positive thymic t cell selection GO:0045059 1 0.489
regulation of leukocyte chemotaxis GO:0002688 46 0.484
immune response GO:0006955 307 0.469
cellular macromolecular complex assembly GO:0034622 324 0.463
t cell selection GO:0045058 4 0.457
cellular response to ammonium ion GO:0071242 4 0.455
t cell proliferation GO:0042098 45 0.427
positive regulation of t cell activation GO:0050870 54 0.421
cellular homeostasis GO:0019725 196 0.412
regulation of interferon gamma production GO:0032649 36 0.408
b cell homeostasis GO:0001782 1 0.405
system process GO:0003008 349 0.401
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.395
negative regulation of multicellular organismal process GO:0051241 317 0.394
humoral immune response GO:0006959 49 0.391
humoral immune response mediated by circulating immunoglobulin GO:0002455 5 0.374
positive regulation of cellular amine metabolic process GO:0033240 7 0.371
peptide transport GO:0015833 74 0.368
positive regulation of leukocyte proliferation GO:0070665 48 0.364
amine metabolic process GO:0009308 44 0.363
cellular amine metabolic process GO:0044106 41 0.359
detection of external biotic stimulus GO:0098581 19 0.359
regulation of cellular ketone metabolic process GO:0010565 50 0.352
regulation of cytokine production GO:0001817 232 0.349
regulation of cellular amino acid metabolic process GO:0006521 6 0.346
secretion GO:0046903 254 0.345
leukocyte migration GO:0050900 107 0.339
de novo posttranslational protein folding GO:0051084 2 0.338
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.333
hematopoietic or lymphoid organ development GO:0048534 186 0.327
neurological system process GO:0050877 163 0.327
negative regulation of apoptotic signaling pathway GO:2001234 97 0.323
regulation of t cell activation GO:0050863 77 0.319
small molecule biosynthetic process GO:0044283 157 0.309
regulation of leukocyte migration GO:0002685 63 0.305
positive regulation of protein phosphorylation GO:0001934 313 0.302
detection of biotic stimulus GO:0009595 21 0.290
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.280
regulation of immune effector process GO:0002697 91 0.274
regulation of chemotaxis GO:0050920 74 0.272
immune system development GO:0002520 195 0.268
unsaturated fatty acid metabolic process GO:0033559 37 0.267
positive regulation of t cell differentiation GO:0045582 11 0.267
positive regulation of immune response GO:0050778 159 0.261
protein carbohydrate complex assembly GO:0065006 2 0.261
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.255
negative regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002587 2 0.251
negative regulation of cell adhesion GO:0007162 64 0.249
positive regulation of protein kinase activity GO:0045860 190 0.246
negative regulation of granulocyte chemotaxis GO:0071623 2 0.243
innate immune response GO:0045087 178 0.242
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.239
regulation of immune response GO:0050776 201 0.239
response to oxygen containing compound GO:1901700 369 0.236
positive regulation of cell activation GO:0050867 81 0.235
positive regulation of leukocyte differentiation GO:1902107 37 0.234
mapk cascade GO:0000165 288 0.234
positive regulation of cell differentiation GO:0045597 211 0.231
secretion by cell GO:0032940 226 0.227
positive regulation of t helper 1 type immune response GO:0002827 4 0.223
response to bacterium GO:0009617 144 0.220
defense response GO:0006952 315 0.217
positive regulation of leukocyte activation GO:0002696 80 0.214
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.207
cytokine secretion GO:0050663 64 0.206
inflammatory response to antigenic stimulus GO:0002437 4 0.201
hemopoiesis GO:0030097 180 0.201
negative regulation of defense response GO:0031348 47 0.198
chemokine c x c motif ligand 2 production GO:0072567 3 0.196
negative regulation of b cell apoptotic process GO:0002903 4 0.196
negative regulation of lymphocyte activation GO:0051250 24 0.196
regulation of antigen processing and presentation GO:0002577 6 0.194
regulation of cell migration GO:0030334 289 0.194
cellular amino acid metabolic process GO:0006520 116 0.194
antigen processing and presentation of polysaccharide antigen via mhc class ii GO:0002505 2 0.190
regulation of cell adhesion GO:0030155 166 0.190
regulation of cytokine production involved in immune response GO:0002718 22 0.186
interleukin 10 production GO:0032613 17 0.183
positive regulation of behavior GO:0048520 60 0.183
cellular ketone metabolic process GO:0042180 80 0.181
protein processing GO:0016485 226 0.180
cellular response to cytokine stimulus GO:0071345 181 0.179
negative regulation of cell activation GO:0050866 33 0.177
fatty acid derivative metabolic process GO:1901568 35 0.175
chaperone mediated protein folding GO:0061077 13 0.175
regulation of cellular amine metabolic process GO:0033238 11 0.169
intracellular protein transport GO:0006886 270 0.165
cell chemotaxis GO:0060326 112 0.165
cytokine mediated signaling pathway GO:0019221 109 0.162
mhc protein complex assembly GO:0002396 4 0.162
fatty acid biosynthetic process GO:0006633 46 0.157
protein maturation GO:0051604 233 0.157
regulation of homeostatic process GO:0032844 121 0.155
monocarboxylic acid biosynthetic process GO:0072330 67 0.154
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.153
prostaglandin metabolic process GO:0006693 17 0.151
negative regulation of response to wounding GO:1903035 47 0.151
regulation of secretion GO:0051046 194 0.149
granulocyte migration GO:0097530 40 0.148
negative regulation of peptidase activity GO:0010466 91 0.146
positive regulation of cell proliferation GO:0008284 301 0.145
regulation of neutrophil migration GO:1902622 10 0.143
response to hexose GO:0009746 20 0.142
monocarboxylic acid metabolic process GO:0032787 185 0.142
negative regulation of homeostatic process GO:0032845 59 0.141
protein secretion GO:0009306 98 0.138
unsaturated fatty acid biosynthetic process GO:0006636 21 0.138
positive regulation of immune system process GO:0002684 283 0.137
negative regulation of inflammatory response to antigenic stimulus GO:0002862 2 0.136
negative regulation of t cell activation GO:0050868 18 0.136
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.135
negative regulation of protein metabolic process GO:0051248 391 0.133
t helper 1 type immune response GO:0042088 8 0.133
positive regulation of cell migration GO:0030335 172 0.133
peptidyl tyrosine phosphorylation GO:0018108 170 0.130
thymic t cell selection GO:0045061 2 0.130
regulation of defense response GO:0031347 154 0.129
positive regulation of developmental process GO:0051094 314 0.128
regulation of leukocyte differentiation GO:1902105 61 0.128
leukocyte differentiation GO:0002521 98 0.127
negative regulation of cell differentiation GO:0045596 171 0.127
regulation of apoptotic signaling pathway GO:2001233 175 0.124
regulation of protein kinase activity GO:0045859 289 0.120
negative regulation of protein maturation GO:1903318 142 0.120
erk1 and erk2 cascade GO:0070371 104 0.118
prostanoid biosynthetic process GO:0046457 11 0.117
response to cytokine GO:0034097 232 0.117
negative regulation of programmed cell death GO:0043069 321 0.117
adaptive immune response GO:0002250 49 0.116
regulation of granulocyte chemotaxis GO:0071622 16 0.115
protein folding GO:0006457 38 0.111
negative regulation of protein processing GO:0010955 142 0.107
nitrogen compound transport GO:0071705 191 0.106
regulation of b cell proliferation GO:0030888 18 0.106
immunoglobulin mediated immune response GO:0016064 10 0.105
negative regulation of t cell proliferation GO:0042130 8 0.105
negative regulation of hydrolase activity GO:0051346 182 0.104
positive regulation of response to external stimulus GO:0032103 88 0.104
regulation of locomotion GO:0040012 329 0.104
t cell differentiation in thymus GO:0033077 4 0.103
regulation of leukocyte apoptotic process GO:2000106 25 0.102
regulation of response to wounding GO:1903034 101 0.101
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.100
leukocyte mediated immunity GO:0002443 59 0.097
regulation of kinase activity GO:0043549 314 0.096
positive regulation of peptide hormone secretion GO:0090277 15 0.096
regulation of erk1 and erk2 cascade GO:0070372 99 0.095
signal transduction by phosphorylation GO:0023014 297 0.095
icosanoid metabolic process GO:0006690 35 0.095
positive regulation of secretion GO:0051047 116 0.094
biological adhesion GO:0022610 331 0.093
positive regulation of kinase activity GO:0033674 204 0.093
taxis GO:0042330 157 0.089
activation of protein kinase activity GO:0032147 90 0.089
cellular response to oxygen containing compound GO:1901701 276 0.088
negative regulation of catalytic activity GO:0043086 335 0.088
positive regulation of neutrophil migration GO:1902624 7 0.087
lipid biosynthetic process GO:0008610 177 0.086
regulation of nervous system development GO:0051960 88 0.085
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.084
positive regulation of cellular component movement GO:0051272 181 0.084
negative regulation of neuron differentiation GO:0045665 21 0.083
regulation of proteolysis GO:0030162 293 0.082
production of molecular mediator of immune response GO:0002440 37 0.082
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.081
regulation of cell motility GO:2000145 299 0.081
lymphocyte homeostasis GO:0002260 4 0.080
negative regulation of developmental process GO:0051093 247 0.079
negative regulation of cell death GO:0060548 345 0.078
cell projection organization GO:0030030 252 0.078
regulation of mapk cascade GO:0043408 262 0.077
regulation of secretion by cell GO:1903530 177 0.075
positive regulation of transferase activity GO:0051347 227 0.075
positive regulation of phosphorylation GO:0042327 394 0.075
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.074
regulation of cellular response to stress GO:0080135 244 0.074
positive regulation of neutrophil chemotaxis GO:0090023 7 0.072
regulation of response to external stimulus GO:0032101 222 0.072
lipid metabolic process GO:0006629 381 0.072
b cell mediated immunity GO:0019724 10 0.070
intrinsic apoptotic signaling pathway GO:0097193 127 0.070
peptidyl tyrosine modification GO:0018212 170 0.070
negative regulation of cellular component organization GO:0051129 235 0.069
regulation of transferase activity GO:0051338 355 0.069
positive regulation of leukocyte migration GO:0002687 46 0.068
regulation of cell development GO:0060284 161 0.067
positive regulation of transport GO:0051050 336 0.067
antigen processing and presentation of exogenous antigen GO:0019884 4 0.067
negative regulation of response to dna damage stimulus GO:2001021 33 0.065
regulation of glial cell differentiation GO:0045685 3 0.064
negative regulation of cellular protein metabolic process GO:0032269 353 0.063
chemokine production GO:0032602 32 0.062
positive regulation of cell motility GO:2000147 177 0.061
positive regulation of cytokine production GO:0001819 167 0.061
positive regulation of chemotaxis GO:0050921 57 0.061
cell type specific apoptotic process GO:0097285 125 0.060
b cell activation GO:0042113 33 0.059
chemokine mediated signaling pathway GO:0070098 16 0.058
leukocyte apoptotic process GO:0071887 31 0.058
regulation of endopeptidase activity GO:0052548 170 0.058
negative regulation of neuron projection development GO:0010977 15 0.058
negative regulation of apoptotic process GO:0043066 316 0.057
positive regulation of mapk cascade GO:0043410 190 0.057
cell development GO:0048468 328 0.056
regulation of peptidase activity GO:0052547 180 0.055
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.054
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.053
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.052
organic acid biosynthetic process GO:0016053 97 0.052
regulation of protein processing GO:0070613 150 0.052
granulocyte chemotaxis GO:0071621 37 0.052
regulation of b cell activation GO:0050864 24 0.051
regulation of t cell differentiation GO:0045580 19 0.051
b cell proliferation GO:0042100 22 0.051
positive regulation of cell death GO:0010942 263 0.051
endocytosis GO:0006897 159 0.051
hormone secretion GO:0046879 65 0.051
positive regulation of insulin secretion GO:0032024 10 0.050
cellular response to molecule of bacterial origin GO:0071219 62 0.050
fibroblast proliferation GO:0048144 33 0.050
apoptotic signaling pathway GO:0097190 268 0.050
positive t cell selection GO:0043368 2 0.050
prostanoid metabolic process GO:0006692 17 0.050
regulation of cell projection organization GO:0031344 107 0.049
neuron differentiation GO:0030182 138 0.049
cell adhesion GO:0007155 325 0.049
myeloid dendritic cell chemotaxis GO:0002408 3 0.049
regulation of cell substrate adhesion GO:0010810 68 0.049
immune effector process GO:0002252 159 0.048
post embryonic development GO:0009791 2 0.048
response to fungus GO:0009620 4 0.048
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.047
regulation of peptide transport GO:0090087 62 0.047
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.047
negative regulation of intracellular signal transduction GO:1902532 183 0.047
negative regulation of cell substrate adhesion GO:0010812 24 0.047
negative regulation of leukocyte differentiation GO:1902106 24 0.047
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.046
negative regulation of blood vessel morphogenesis GO:2000181 41 0.046
regulation of type 2 immune response GO:0002828 5 0.046
regulation of response to dna damage stimulus GO:2001020 94 0.046
regulation of behavior GO:0050795 82 0.046
regulation of interleukin 4 production GO:0032673 7 0.045
cation transport GO:0006812 331 0.044
negative regulation of transport GO:0051051 176 0.044
regulation of protein serine threonine kinase activity GO:0071900 179 0.044
positive regulation of chemokine production GO:0032722 22 0.043
regulation of cellular component movement GO:0051270 334 0.042
negative regulation of endopeptidase activity GO:0010951 84 0.042
endothelial cell migration GO:0043542 86 0.042
chemical homeostasis GO:0048878 306 0.042
lymphocyte apoptotic process GO:0070227 20 0.041
nervous system development GO:0007399 293 0.041
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.041
protein oligomerization GO:0051259 173 0.041
sprouting angiogenesis GO:0002040 29 0.041
positive regulation of fibroblast proliferation GO:0048146 21 0.041
negative regulation of inflammatory response GO:0050728 22 0.041
generation of neurons GO:0048699 152 0.041
negative regulation of proteolysis GO:0045861 132 0.040
blood vessel morphogenesis GO:0048514 162 0.039
signal transduction by p53 class mediator GO:0072331 72 0.039
negative regulation of chemotaxis GO:0050922 13 0.039
regulation of chemokine c x c motif ligand 2 production GO:2000341 2 0.038
lymphocyte differentiation GO:0030098 35 0.038
insulin secretion GO:0030073 39 0.038
regulation of mature b cell apoptotic process GO:0002905 1 0.038
cation homeostasis GO:0055080 189 0.037
regulation of protein transport GO:0051223 213 0.037
response to dexamethasone GO:0071548 1 0.036
positive regulation of peptide secretion GO:0002793 15 0.036
regulation of cell differentiation GO:0045595 393 0.036
fatty acid metabolic process GO:0006631 115 0.036
wound healing GO:0042060 115 0.036
response to organic cyclic compound GO:0014070 204 0.035
regulation of map kinase activity GO:0043405 108 0.035
multicellular organismal signaling GO:0035637 34 0.034
activation of mapk activity GO:0000187 45 0.034
prostaglandin biosynthetic process GO:0001516 11 0.033
ameboidal type cell migration GO:0001667 135 0.033
positive regulation of t cell proliferation GO:0042102 33 0.033
negative regulation of cell development GO:0010721 48 0.033
positive regulation of locomotion GO:0040017 186 0.033
chemotaxis GO:0006935 157 0.032
signal release GO:0023061 70 0.032
receptor metabolic process GO:0043112 81 0.032
response to molecule of bacterial origin GO:0002237 82 0.032
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.032
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.031
positive regulation of hormone secretion GO:0046887 25 0.031
regulation of protein maturation GO:1903317 150 0.031
negative regulation of signal transduction by p53 class mediator GO:1901797 15 0.031
regulation of complement activation lectin pathway GO:0001868 2 0.031
inflammatory response GO:0006954 79 0.031
neurogenesis GO:0022008 169 0.031
response to external biotic stimulus GO:0043207 261 0.031
regulation of lymphocyte apoptotic process GO:0070228 15 0.031
cellular response to glucocorticoid stimulus GO:0071385 4 0.031
regulation of cytokine secretion GO:0050707 57 0.030
response to glucose GO:0009749 19 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
negative regulation of leukocyte migration GO:0002686 14 0.030
myeloid leukocyte cytokine production GO:0061082 5 0.030
regulation of camp metabolic process GO:0030814 52 0.030
negative regulation of immune response GO:0050777 40 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
cytokine production involved in immune response GO:0002367 27 0.029
multicellular organismal homeostasis GO:0048871 67 0.029
positive regulation of secretion by cell GO:1903532 108 0.028
neuron projection development GO:0031175 106 0.028
signal transduction in response to dna damage GO:0042770 57 0.026
neuron development GO:0048666 113 0.026
regulation of neurogenesis GO:0050767 82 0.026
regulation of signal transduction by p53 class mediator GO:1901796 26 0.026
ras protein signal transduction GO:0007265 73 0.026
behavior GO:0007610 112 0.026
multicellular organismal aging GO:0010259 3 0.026
regulation of vasculature development GO:1901342 97 0.026
neutrophil chemotaxis GO:0030593 24 0.026
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.026
leukocyte chemotaxis GO:0030595 76 0.025
regulation of protein secretion GO:0050708 86 0.025
cellular divalent inorganic cation homeostasis GO:0072503 128 0.025
regulation of lymphocyte differentiation GO:0045619 22 0.024
regulation of antigen processing and presentation of peptide antigen GO:0002583 4 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
cellular cation homeostasis GO:0030003 163 0.024
organophosphate catabolic process GO:0046434 430 0.024
positive regulation of b cell activation GO:0050871 17 0.024
patterning of blood vessels GO:0001569 2 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.023
small gtpase mediated signal transduction GO:0007264 78 0.023
motor neuron axon guidance GO:0008045 2 0.023
regulation of neuron projection development GO:0010975 57 0.023
negative regulation of neutrophil chemotaxis GO:0090024 2 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
cellular response to glucose stimulus GO:0071333 10 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
regulation of protein localization GO:0032880 296 0.022
positive regulation of granulocyte chemotaxis GO:0071624 9 0.022
actin cytoskeleton organization GO:0030036 207 0.022
protein tetramerization GO:0051262 47 0.021
regulation of production of molecular mediator of immune response GO:0002700 25 0.021
regulation of peptide secretion GO:0002791 42 0.021
negative regulation of secretion GO:0051048 58 0.021
type 2 immune response GO:0042092 6 0.021
chemokine c c motif ligand 11 production GO:0071954 1 0.021
regulation of growth GO:0040008 165 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
icosanoid biosynthetic process GO:0046456 18 0.020
response to corticosteroid GO:0031960 15 0.020
cell morphogenesis GO:0000902 296 0.020
purine containing compound catabolic process GO:0072523 411 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
cellular protein catabolic process GO:0044257 261 0.020
regeneration GO:0031099 4 0.020
regulation of b cell apoptotic process GO:0002902 5 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
positive regulation of adaptive immune response GO:0002821 21 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
regulation of neuron differentiation GO:0045664 70 0.019
positive regulation of nervous system development GO:0051962 54 0.019
cellular response to hormone stimulus GO:0032870 125 0.019
organelle assembly GO:0070925 176 0.019
astrocyte chemotaxis GO:0035700 1 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
nucleoside catabolic process GO:0009164 408 0.019
positive regulation of antigen processing and presentation GO:0002579 1 0.019
ion homeostasis GO:0050801 230 0.019
negative regulation of cell projection organization GO:0031345 22 0.019
regulation of macrophage cytokine production GO:0010935 4 0.019
response to abiotic stimulus GO:0009628 336 0.018
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 20 0.018
protein catabolic process GO:0030163 325 0.018
positive regulation of type 2 immune response GO:0002830 2 0.018
regulation of positive chemotaxis GO:0050926 14 0.018
response to oxygen levels GO:0070482 100 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
amide transport GO:0042886 76 0.018
interleukin 4 production GO:0032633 7 0.018
cellular response to oxidative stress GO:0034599 85 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
action potential GO:0001508 34 0.018
positive regulation of b cell proliferation GO:0030890 12 0.018
epithelial cell migration GO:0010631 119 0.018
muscle system process GO:0003012 81 0.017
cellular calcium ion homeostasis GO:0006874 117 0.017
vesicle mediated transport GO:0016192 371 0.017
regulation of ion transport GO:0043269 189 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
response to hormone GO:0009725 175 0.017
vasculature development GO:0001944 181 0.017
camp metabolic process GO:0046058 61 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
membrane organization GO:0061024 292 0.017
gtp catabolic process GO:0006184 237 0.017
regulation of peptide hormone secretion GO:0090276 41 0.017
positive regulation of ion transport GO:0043270 87 0.017
rho protein signal transduction GO:0007266 26 0.017
regulation of cell cycle GO:0051726 393 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
mitotic cell cycle GO:0000278 326 0.016
regulation of response to cytokine stimulus GO:0060759 46 0.016
cellular ion homeostasis GO:0006873 168 0.016
homeostasis of number of cells GO:0048872 40 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cellular response to ketone GO:1901655 9 0.016
regulation of cell growth GO:0001558 135 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
growth GO:0040007 202 0.016
maintenance of location GO:0051235 112 0.016
positive regulation of response to cytokine stimulus GO:0060760 13 0.016
response to monosaccharide GO:0034284 20 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
determination of adult lifespan GO:0008340 2 0.016
detection of chemical stimulus GO:0009593 55 0.016
oogenesis GO:0048477 2 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
cell part morphogenesis GO:0032990 137 0.015
actin filament based process GO:0030029 224 0.015
peptide hormone secretion GO:0030072 50 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
regulation of fibroblast proliferation GO:0048145 32 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of dendritic cell differentiation GO:2001198 3 0.015
hormone transport GO:0009914 68 0.015
circadian behavior GO:0048512 2 0.015
regulation of endothelial cell proliferation GO:0001936 56 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
nucleotide catabolic process GO:0009166 408 0.014
regulation of insulin secretion GO:0050796 33 0.014
epithelial cell differentiation GO:0030855 141 0.014
macrophage cytokine production GO:0010934 4 0.014
anatomical structure homeostasis GO:0060249 100 0.014
cell growth GO:0016049 160 0.014
positive regulation of camp metabolic process GO:0030816 41 0.014
ribonucleotide catabolic process GO:0009261 405 0.014

HLA-DPA1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.838
hypersensitivity reaction disease DOID:0060056 25 0.721
musculoskeletal system disease DOID:17 223 0.108
central nervous system disease DOID:331 186 0.104
neurodegenerative disease DOID:1289 102 0.104
nervous system disease DOID:863 431 0.104
connective tissue disease DOID:65 109 0.076
bone disease DOID:0080001 88 0.047
disease of metabolism DOID:0014667 295 0.022
brain disease DOID:936 73 0.015