Homo sapiens

143 known processes

CD46

CD46 molecule, complement regulatory protein

(Aliases: MGC26544,TLX,MIC10,AHUS2,TRA2.10,MCP)

CD46 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 292 0.256
synaptic transmission cholinergic GO:0007271 2 0.175
system process GO:0003008 349 0.126
cell adhesion GO:0007155 325 0.116
biological adhesion GO:0022610 331 0.114
positive regulation of transport GO:0051050 336 0.113
intracellular protein transport GO:0006886 270 0.112
nucleoside triphosphate catabolic process GO:0009143 394 0.110
protein glycosylation GO:0006486 62 0.110
organophosphate catabolic process GO:0046434 430 0.099
memory GO:0007613 3 0.092
monocyte activation GO:0042117 3 0.078
taxis GO:0042330 157 0.076
glycosylation GO:0070085 71 0.073
negative regulation of protein modification process GO:0031400 200 0.071
negative regulation of hydrolase activity GO:0051346 182 0.069
negative regulation of protein metabolic process GO:0051248 391 0.067
Human Rat
single organism membrane organization GO:0044802 268 0.057
post embryonic development GO:0009791 2 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.053
positive regulation of cell motility GO:2000147 177 0.051
endosomal transport GO:0016197 129 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
cytokine production GO:0001816 247 0.049
regulation of cellular amino acid metabolic process GO:0006521 6 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.047
snare complex assembly GO:0035493 3 0.047
synaptic vesicle endocytosis GO:0048488 2 0.046
cytoplasmic transport GO:0016482 379 0.045
positive regulation of hydrolase activity GO:0051345 331 0.045
vesicle organization GO:0016050 62 0.045
carbohydrate metabolic process GO:0005975 207 0.044
determination of adult lifespan GO:0008340 2 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.042
anion transport GO:0006820 161 0.041
endomembrane system organization GO:0010256 196 0.040
cellular macromolecular complex assembly GO:0034622 324 0.040
cellular amino acid metabolic process GO:0006520 116 0.040
positive regulation of response to external stimulus GO:0032103 88 0.040
protein localization to membrane GO:0072657 160 0.040
negative regulation of peptidase activity GO:0010466 91 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.037
cell activation GO:0001775 213 0.037
purine containing compound catabolic process GO:0072523 411 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
exocytosis GO:0006887 71 0.036
cellular ketone metabolic process GO:0042180 80 0.036
positive regulation of behavior GO:0048520 60 0.036
cellular amine metabolic process GO:0044106 41 0.035
regulation of immune response GO:0050776 201 0.035
neurological system process GO:0050877 163 0.035
positive regulation of catabolic process GO:0009896 310 0.035
Human
cellular response to growth factor stimulus GO:0071363 197 0.035
regulation of intracellular transport GO:0032386 195 0.034
regulation of establishment of protein localization GO:0070201 242 0.034
alcohol biosynthetic process GO:0046165 52 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.034
single organism membrane fusion GO:0044801 37 0.033
establishment of protein localization to membrane GO:0090150 121 0.033
lipid metabolic process GO:0006629 381 0.033
long term memory GO:0007616 2 0.033
ras protein signal transduction GO:0007265 73 0.033
glycoprotein biosynthetic process GO:0009101 91 0.032
regulation of proteolysis GO:0030162 293 0.032
protein localization to organelle GO:0033365 280 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.032
glycosyl compound catabolic process GO:1901658 413 0.031
vesicle mediated transport GO:0016192 371 0.031
positive regulation of locomotion GO:0040017 186 0.031
protein processing GO:0016485 226 0.031
Human Rat
regulation of nucleoside metabolic process GO:0009118 209 0.030
negative regulation of cellular component organization GO:0051129 235 0.030
macromolecule glycosylation GO:0043413 63 0.030
regulation of peptidase activity GO:0052547 180 0.030
cellular lipid metabolic process GO:0044255 303 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
Rat
lipid biosynthetic process GO:0008610 177 0.029
receptor metabolic process GO:0043112 81 0.028
positive regulation of nucleoside metabolic process GO:0045979 186 0.028
blood vessel morphogenesis GO:0048514 162 0.028
regulation of cell motility GO:2000145 299 0.028
cellular amide metabolic process GO:0043603 69 0.028
somitogenesis GO:0001756 2 0.027
amine metabolic process GO:0009308 44 0.027
regulation of cytokine production GO:0001817 232 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
actin filament based process GO:0030029 224 0.027
mitochondrion organization GO:0007005 156 0.027
cellular homeostasis GO:0019725 196 0.027
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
establishment of protein localization to organelle GO:0072594 172 0.026
protein targeting GO:0006605 187 0.025
organophosphate ester transport GO:0015748 32 0.025
regulation of lymphocyte migration GO:2000401 22 0.025
regulation of cell adhesion GO:0030155 166 0.025
membrane fusion GO:0061025 43 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
maintenance of location GO:0051235 112 0.024
positive regulation of immune system process GO:0002684 283 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
negative regulation of transport GO:0051051 176 0.024
regulation of protein processing GO:0070613 150 0.024
Human Rat
positive regulation of cytokine production GO:0001819 167 0.024
regulation of glycoprotein metabolic process GO:1903018 19 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
mapk cascade GO:0000165 288 0.023
regulation of cell activation GO:0050865 125 0.023
positive regulation of phosphorylation GO:0042327 394 0.023
atp catabolic process GO:0006200 157 0.023
positive regulation of leukocyte migration GO:0002687 46 0.023
peptidyl tyrosine modification GO:0018212 170 0.023
endocytosis GO:0006897 159 0.023
single organism cellular localization GO:1902580 332 0.022
positive regulation of cell death GO:0010942 263 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
response to growth factor GO:0070848 205 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
innate immune response GO:0045087 178 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
positive regulation of intracellular transport GO:0032388 104 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
leukocyte migration GO:0050900 107 0.021
rho protein signal transduction GO:0007266 26 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
cell projection organization GO:0030030 252 0.021
establishment of protein localization to plasma membrane GO:0090002 68 0.020
transmembrane transport GO:0055085 399 0.020
positive regulation of nucleotide catabolic process GO:0030813 185 0.020
peptidyl tyrosine phosphorylation GO:0018108 170 0.020
multicellular organismal aging GO:0010259 3 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of response to wounding GO:1903034 101 0.020
Human Rat
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
regulation of protein transport GO:0051223 213 0.020
regulation of endopeptidase activity GO:0052548 170 0.019
organelle fusion GO:0048284 36 0.019
synaptic vesicle recycling GO:0036465 3 0.019
organic anion transport GO:0015711 103 0.019
nervous system development GO:0007399 293 0.019
oxidation reduction process GO:0055114 396 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
regulation of locomotion GO:0040012 329 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.018
glycoprotein metabolic process GO:0009100 110 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
regulation of hormone levels GO:0010817 125 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
response to cytokine GO:0034097 232 0.018
regulation of protein localization GO:0032880 296 0.018
negative regulation of protein processing GO:0010955 142 0.018
Human Rat
golgi ribbon formation GO:0090161 3 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
cell morphogenesis GO:0000902 296 0.018
cell chemotaxis GO:0060326 112 0.018
organelle localization GO:0051640 84 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
small molecule biosynthetic process GO:0044283 157 0.017
atp metabolic process GO:0046034 176 0.017
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
negative regulation of protein maturation GO:1903318 142 0.017
Human Rat
cellular protein complex assembly GO:0043623 188 0.017
leukocyte activation GO:0045321 164 0.017
regulation of mapk cascade GO:0043408 262 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
lipid localization GO:0010876 106 0.017
drug transmembrane transport GO:0006855 7 0.017
positive regulation of phagocytosis engulfment GO:0060100 1 0.016
regulation of t cell migration GO:2000404 14 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of transferase activity GO:0051338 355 0.016
ectoderm development GO:0007398 3 0.016
neuron projection development GO:0031175 106 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
lymphocyte migration GO:0072676 28 0.016
renal system process GO:0003014 25 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
immune system development GO:0002520 195 0.016
cell growth GO:0016049 160 0.016
epithelium development GO:0060429 227 0.016
negative regulation of proteolysis GO:0045861 132 0.016
protein maturation GO:0051604 233 0.016
Human Rat
guanosine containing compound catabolic process GO:1901069 239 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
response to biotic stimulus GO:0009607 276 0.016
Human
immune response GO:0006955 307 0.016
ion transmembrane transport GO:0034220 338 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
apoptotic signaling pathway GO:0097190 268 0.015
regulation of cell cycle GO:0051726 393 0.015
neuron development GO:0048666 113 0.015
protein ubiquitination GO:0016567 314 0.015
regulation of protein kinase activity GO:0045859 289 0.015
regulation of cell migration GO:0030334 289 0.015
hemopoiesis GO:0030097 180 0.015
ameboidal type cell migration GO:0001667 135 0.015
metal ion transport GO:0030001 272 0.015
nucleoside catabolic process GO:0009164 408 0.015
leukocyte chemotaxis GO:0030595 76 0.015
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.015
response to tumor necrosis factor GO:0034612 76 0.015
regulation of endocytosis GO:0030100 72 0.015
regulation of secretion GO:0051046 194 0.015
cellular cation homeostasis GO:0030003 163 0.015
Human
primary neural tube formation GO:0014020 3 0.015
cellular component morphogenesis GO:0032989 314 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
positive regulation of leukocyte chemotaxis GO:0002690 38 0.015
regulation of leukocyte migration GO:0002685 63 0.014
positive regulation of immune response GO:0050778 159 0.014
positive regulation of endopeptidase activity GO:0010950 84 0.014
chemotaxis GO:0006935 157 0.014
positive regulation of developmental process GO:0051094 314 0.014
pma inducible membrane protein ectodomain proteolysis GO:0051088 3 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
protein import GO:0017038 130 0.014
negative regulation of cytokine production GO:0001818 82 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
oocyte development GO:0048599 1 0.014
regulation of lipid metabolic process GO:0019216 96 0.014
myosin filament assembly GO:0031034 2 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
positive regulation of proteolysis GO:0045862 142 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
regulation of lymphocyte activation GO:0051249 103 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
regulation of cell growth GO:0001558 135 0.013
neuromuscular junction development GO:0007528 3 0.013
membrane budding GO:0006900 28 0.013
natural killer cell activation involved in immune response GO:0002323 2 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
alcohol metabolic process GO:0006066 114 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
regulation of response to external stimulus GO:0032101 222 0.013
Human Rat
regulation of cellular component movement GO:0051270 334 0.013
regulation of kinase activity GO:0043549 314 0.013
blastoderm segmentation GO:0007350 2 0.013
cell projection morphogenesis GO:0048858 129 0.013
phospholipid translocation GO:0045332 2 0.013
negative regulation of catabolic process GO:0009895 104 0.013
lipid translocation GO:0034204 2 0.013
tripartite regional subdivision GO:0007351 2 0.012
defense response GO:0006952 315 0.012
Human Rat
mitotic cell cycle GO:0000278 326 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of organelle organization GO:0010638 195 0.012
mitochondrion distribution GO:0048311 3 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
n glycan processing GO:0006491 3 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
organ formation GO:0048645 3 0.012
peptide metabolic process GO:0006518 51 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
synaptic vesicle transport GO:0048489 5 0.012
neurotransmitter secretion GO:0007269 4 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of protein maturation GO:1903317 150 0.012
Human Rat
peptidyl serine phosphorylation GO:0018105 101 0.012
regulation of leukocyte chemotaxis GO:0002688 46 0.012
single organism cell adhesion GO:0098602 179 0.012
positive regulation of cell migration GO:0030335 172 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
response to inorganic substance GO:0010035 127 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
organ morphogenesis GO:0009887 147 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.011
eye pigmentation GO:0048069 1 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
gtp catabolic process GO:0006184 237 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
sensory perception of smell GO:0007608 2 0.011
regulation of cellular response to stress GO:0080135 244 0.011
regulation of protein localization to plasma membrane GO:1903076 40 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
cell part morphogenesis GO:0032990 137 0.011
negative regulation of cell cycle GO:0045786 193 0.011
associative learning GO:0008306 1 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
synaptic vesicle exocytosis GO:0016079 3 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.011
beta amyloid metabolic process GO:0050435 12 0.011
actin cytoskeleton organization GO:0030036 207 0.011
regulation of lymphocyte chemotaxis GO:1901623 12 0.011
segmentation GO:0035282 4 0.011
establishment of planar polarity GO:0001736 3 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
rna processing GO:0006396 255 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
gtp metabolic process GO:0046039 239 0.011
wnt signaling pathway GO:0016055 156 0.010
cellular response to reactive oxygen species GO:0034614 50 0.010
regulation of cell cycle process GO:0010564 266 0.010
anterior posterior axis specification GO:0009948 2 0.010
organelle assembly GO:0070925 176 0.010
golgi vesicle transport GO:0048193 80 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
positive regulation of peptidase activity GO:0010952 88 0.010
epithelium migration GO:0090132 119 0.010
cell substrate adhesion GO:0031589 132 0.010
response to salt stress GO:0009651 3 0.010
cell cycle phase transition GO:0044770 173 0.010
phospholipid biosynthetic process GO:0008654 44 0.010

CD46 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.036
disease of cellular proliferation DOID:14566 174 0.036
epilepsy syndrome DOID:1826 41 0.034
central nervous system disease DOID:331 186 0.034
brain disease DOID:936 73 0.034
variable age at onset electroclinical syndrome DOID:0050706 8 0.034
electroclinical syndrome DOID:0050701 32 0.034
progressive myoclonus epilepsy DOID:891 8 0.034
nervous system disease DOID:863 431 0.034
disease of mental health DOID:150 70 0.022
disease of metabolism DOID:0014667 295 0.015
neurodegenerative disease DOID:1289 102 0.013
cognitive disorder DOID:1561 29 0.013
organ system cancer DOID:0050686 164 0.013
sensory system disease DOID:0050155 203 0.012
tauopathy DOID:680 16 0.011
inherited metabolic disorder DOID:655 242 0.010
immune system disease DOID:2914 155 0.004
hematopoietic system disease DOID:74 100 0.004
anemia DOID:2355 55 0.002
hemolytic anemia DOID:583 20 0.001
normocytic anemia DOID:720 20 0.001
hemolytic uremic syndrome DOID:12554 8 0.000