Homo sapiens

45 known processes

PRPF8

PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)

(Aliases: RP13,PRPC8,PRP8,HPRP8)

PRPF8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing GO:0008380 131 0.995
mrna metabolic process GO:0016071 175 0.993
spliceosomal tri snrnp complex assembly GO:0000244 7 0.988
rna processing GO:0006396 255 0.985
spliceosomal snrnp assembly GO:0000387 28 0.983
post embryonic development GO:0009791 2 0.974
Worm
mrna splicing via spliceosome GO:0000398 89 0.964
regulation of meiotic cell cycle GO:0051445 4 0.927
spliceosomal complex assembly GO:0000245 17 0.833
Yeast
rna splicing via transesterification reactions GO:0000375 90 0.792
mrna processing GO:0006397 133 0.786
regulation of meiosis GO:0040020 3 0.607
regulation of nuclear division GO:0051783 65 0.562
mitotic cell cycle process GO:1903047 286 0.498
microtubule cytoskeleton organization GO:0000226 176 0.425
behavior GO:0007610 112 0.420
cellular macromolecular complex assembly GO:0034622 324 0.402
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.359
regulation of cell cycle GO:0051726 393 0.347
anatomical structure formation involved in morphogenesis GO:0048646 284 0.308
oogenesis GO:0048477 2 0.282
spindle organization GO:0007051 53 0.279
ribonucleoprotein complex assembly GO:0022618 78 0.278
ribonucleoprotein complex biogenesis GO:0022613 116 0.269
cell development GO:0048468 328 0.263
molting cycle GO:0042303 28 0.240
Worm
purine nucleoside monophosphate catabolic process GO:0009128 158 0.203
sex differentiation GO:0007548 45 0.197
Worm
growth GO:0040007 202 0.139
ribonucleoside monophosphate metabolic process GO:0009161 187 0.134
ribonucleoprotein complex subunit organization GO:0071826 81 0.133
single organism reproductive process GO:0044702 98 0.133
Worm
purine ribonucleotide catabolic process GO:0009154 404 0.128
reproductive system development GO:0061458 56 0.118
Worm
cellular protein complex assembly GO:0043623 188 0.111
demethylation GO:0070988 37 0.111
regulation of astrocyte differentiation GO:0048710 3 0.110
ossification GO:0001503 121 0.101
osteoblast differentiation GO:0001649 92 0.101
cellular protein catabolic process GO:0044257 261 0.098
regulation of immune effector process GO:0002697 91 0.096
mitotic cell cycle GO:0000278 326 0.092
reproductive structure development GO:0048608 55 0.091
Worm
regulation of cell division GO:0051302 116 0.089
generation of neurons GO:0048699 152 0.086
meiotic cell cycle GO:0051321 13 0.080
proteasomal protein catabolic process GO:0010498 176 0.076
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.072
negative regulation of multi organism process GO:0043901 92 0.071
lymphocyte activation GO:0046649 133 0.067
cellular response to dna damage stimulus GO:0006974 379 0.067
purine ribonucleoside catabolic process GO:0046130 398 0.066
single organism cellular localization GO:1902580 332 0.062
embryo development ending in birth or egg hatching GO:0009792 34 0.060
Worm
protein alkylation GO:0008213 74 0.059
neurogenesis GO:0022008 169 0.058
Fly
regulation of multi organism process GO:0043900 157 0.057
female gamete generation GO:0007292 2 0.053
chordate embryonic development GO:0043009 34 0.051
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
oocyte development GO:0048599 1 0.050
mrna splice site selection GO:0006376 7 0.050
Yeast
lipid metabolic process GO:0006629 381 0.050
ncrna metabolic process GO:0034660 108 0.050
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.048
defense response GO:0006952 315 0.047
protein catabolic process GO:0030163 325 0.046
mitotic spindle organization GO:0007052 27 0.046
oocyte differentiation GO:0009994 2 0.046
embryo development GO:0009790 123 0.045
Worm
astrocyte differentiation GO:0048708 4 0.043
ras protein signal transduction GO:0007265 73 0.042
endocytosis GO:0006897 159 0.042
Worm
small gtpase mediated signal transduction GO:0007264 78 0.042
striated muscle myosin thick filament assembly GO:0071688 2 0.041
histone modification GO:0016570 251 0.041
myosin filament assembly GO:0031034 2 0.039
negative regulation of mitotic cell cycle GO:0045930 102 0.039
positive regulation of mrna metabolic process GO:1903313 19 0.038
myosin filament organization GO:0031033 2 0.038
regulation of cell cycle process GO:0010564 266 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.037
protein modification by small protein removal GO:0070646 92 0.037
nucleoside monophosphate catabolic process GO:0009125 159 0.037
ribonucleotide catabolic process GO:0009261 405 0.036
meiotic nuclear division GO:0007126 10 0.035
regulation of mrna splicing via spliceosome GO:0048024 32 0.033
purine nucleotide catabolic process GO:0006195 405 0.032
nucleotide catabolic process GO:0009166 408 0.032
ribonucleoside catabolic process GO:0042454 406 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.031
protein modification by small protein conjugation GO:0032446 342 0.030
dna damage checkpoint GO:0000077 68 0.030
regulation of response to external stimulus GO:0032101 222 0.030
multicellular organismal reproductive process GO:0048609 40 0.030
mapk cascade GO:0000165 288 0.030
vesicle mediated transport GO:0016192 371 0.029
Worm
cell division GO:0051301 168 0.028
positive regulation of phosphorylation GO:0042327 394 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
erk1 and erk2 cascade GO:0070371 104 0.025
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
mitotic nuclear division GO:0007067 119 0.024
regulation of viral process GO:0050792 103 0.023
regulation of ras protein signal transduction GO:0046578 155 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
chromatin organization GO:0006325 351 0.022
developmental process involved in reproduction GO:0003006 66 0.022
Worm
cellular response to growth factor stimulus GO:0071363 197 0.022
positive regulation of erbb signaling pathway GO:1901186 11 0.022
anterior posterior axis specification GO:0009948 2 0.022
regulation of cellular component movement GO:0051270 334 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.021
microtubule based process GO:0007017 210 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
regulation of small gtpase mediated signal transduction GO:0051056 156 0.020
immune effector process GO:0002252 159 0.020
development of primary sexual characteristics GO:0045137 35 0.019
Worm
atp metabolic process GO:0046034 176 0.019
central nervous system development GO:0007417 123 0.019
reproductive process GO:0022414 106 0.019
Worm
double strand break repair GO:0006302 101 0.018
protein ubiquitination GO:0016567 314 0.018
protein polyubiquitination GO:0000209 110 0.018
atp catabolic process GO:0006200 157 0.018
dna repair GO:0006281 198 0.018
multi multicellular organism process GO:0044706 18 0.017
protein import GO:0017038 130 0.017
tissue morphogenesis GO:0048729 96 0.017
multicellular organism reproduction GO:0032504 42 0.017
response to endoplasmic reticulum stress GO:0034976 49 0.017
regulation of defense response GO:0031347 154 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.017
cellular component morphogenesis GO:0032989 314 0.016
thymus development GO:0048538 3 0.016
somitogenesis GO:0001756 2 0.016
protein deubiquitination GO:0016579 79 0.016
dna biosynthetic process GO:0071897 40 0.015
cell projection morphogenesis GO:0048858 129 0.015
negative regulation of cell cycle GO:0045786 193 0.015
regulation of behavior GO:0050795 82 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
response to external biotic stimulus GO:0043207 261 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
leukocyte activation GO:0045321 164 0.014
positive regulation of immune system process GO:0002684 283 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
tube development GO:0035295 125 0.014
blood vessel development GO:0001568 172 0.014
blastocyst development GO:0001824 3 0.014
regulation of dna metabolic process GO:0051052 153 0.014
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.013
negative regulation of response to external stimulus GO:0032102 83 0.013
organophosphate catabolic process GO:0046434 430 0.013
negative regulation of immune effector process GO:0002698 38 0.013
nuclear division GO:0000280 128 0.013
regulation of cell motility GO:2000145 299 0.013
dna demethylation GO:0080111 12 0.013
epithelium development GO:0060429 227 0.013
positive regulation of leukocyte activation GO:0002696 80 0.013
response to abiotic stimulus GO:0009628 336 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
vasculature development GO:0001944 181 0.013
determination of adult lifespan GO:0008340 2 0.013
negative regulation of defense response GO:0031348 47 0.013
regulation of rna splicing GO:0043484 62 0.013
actomyosin structure organization GO:0031032 59 0.013
organelle fission GO:0048285 149 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
methylation GO:0032259 106 0.012
protein dna complex subunit organization GO:0071824 80 0.012
regulation of cellular response to stress GO:0080135 244 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of developmental process GO:0051094 314 0.012
reproduction GO:0000003 63 0.012
Worm
regulation of cell migration GO:0030334 289 0.012
regulation of rna stability GO:0043487 23 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
response to transforming growth factor beta GO:0071559 94 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.011
eye development GO:0001654 42 0.011
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.011
cell activation GO:0001775 213 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
response to biotic stimulus GO:0009607 276 0.011
taxis GO:0042330 157 0.011
cellular response to lipid GO:0071396 127 0.010
protein demethylation GO:0006482 17 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
cellular carbohydrate metabolic process GO:0044262 84 0.010
regulation of cytokine production GO:0001817 232 0.010
heart development GO:0007507 95 0.010
multi organism behavior GO:0051705 14 0.010

PRPF8 disease predictions

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 118 0.959
sensory system disease DOID:0050155 203 0.959
eye and adnexa disease DOID:1492 150 0.959
nervous system disease DOID:863 431 0.959
eye disease DOID:5614 149 0.959
retinal degeneration DOID:8466 89 0.959
retinitis pigmentosa DOID:10584 51 0.959
neuromuscular disease DOID:440 38 0.028
charcot marie tooth disease type 2 DOID:0050539 15 0.028
charcot marie tooth disease DOID:10595 33 0.028
neuropathy DOID:870 52 0.028
central nervous system disease DOID:331 186 0.012
neurodegenerative disease DOID:1289 102 0.012