Homo sapiens

0 known processes

PAK4

p21 protein (Cdc42/Rac)-activated kinase 4

PAK4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein polymerization GO:0032271 63 0.689
regulation of actin filament polymerization GO:0030833 50 0.676
cellular component morphogenesis GO:0032989 314 0.636
rho protein signal transduction GO:0007266 26 0.610
guanosine containing compound catabolic process GO:1901069 239 0.560
regulation of cellular component size GO:0032535 82 0.557
Fly
regulation of rho protein signal transduction GO:0035023 79 0.529
purine nucleoside triphosphate catabolic process GO:0009146 392 0.499
nervous system development GO:0007399 293 0.496
Fly
gtp metabolic process GO:0046039 239 0.475
guanosine containing compound metabolic process GO:1901068 244 0.422
nucleoside triphosphate metabolic process GO:0009141 422 0.421
cell morphogenesis GO:0000902 296 0.415
regulation of actin filament based process GO:0032970 141 0.401
organophosphate catabolic process GO:0046434 430 0.373
actin filament polymerization GO:0030041 45 0.371
ribonucleoside triphosphate catabolic process GO:0009203 391 0.364
positive regulation of cellular component organization GO:0051130 376 0.356
positive regulation of actin filament polymerization GO:0030838 38 0.356
regulation of cellular component biogenesis GO:0044087 281 0.342
ribonucleoside catabolic process GO:0042454 406 0.340
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.339
actin filament based process GO:0030029 224 0.336
regulation of gtpase activity GO:0043087 180 0.329
regulation of cytoskeleton organization GO:0051493 177 0.329
purine nucleoside triphosphate metabolic process GO:0009144 412 0.312
nucleoside catabolic process GO:0009164 408 0.307
purine nucleoside catabolic process GO:0006152 398 0.303
regulation of actin cytoskeleton organization GO:0032956 116 0.297
nucleotide catabolic process GO:0009166 408 0.283
regulation of cellular ketone metabolic process GO:0010565 50 0.275
purine ribonucleoside catabolic process GO:0046130 398 0.275
neuromuscular junction development GO:0007528 3 0.270
neuron differentiation GO:0030182 138 0.266
Fly
purine containing compound catabolic process GO:0072523 411 0.265
negative regulation of developmental process GO:0051093 247 0.264
protein polymerization GO:0051258 71 0.257
regulation of actin filament length GO:0030832 56 0.250
actin cytoskeleton organization GO:0030036 207 0.248
actin filament organization GO:0007015 128 0.241
cell projection organization GO:0030030 252 0.240
positive regulation of cellular component biogenesis GO:0044089 158 0.240
purine nucleotide catabolic process GO:0006195 405 0.238
regulation of anatomical structure morphogenesis GO:0022603 286 0.237
Fly
regulation of actin polymerization or depolymerization GO:0008064 56 0.226
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.219
peptidyl serine phosphorylation GO:0018105 101 0.216
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.211
post embryonic development GO:0009791 2 0.204
regulation of anatomical structure size GO:0090066 101 0.201
Fly
cellular protein complex assembly GO:0043623 188 0.200
neuron projection development GO:0031175 106 0.197
positive regulation of rho gtpase activity GO:0032321 56 0.193
glycosyl compound catabolic process GO:1901658 413 0.191
regulation of cell projection organization GO:0031344 107 0.188
actin polymerization or depolymerization GO:0008154 56 0.181
regulation of transferase activity GO:0051338 355 0.180
nucleoside phosphate catabolic process GO:1901292 412 0.176
nucleoside triphosphate catabolic process GO:0009143 394 0.176
regulation of purine nucleotide metabolic process GO:1900542 264 0.175
regulation of cellular amine metabolic process GO:0033238 11 0.172
epithelium development GO:0060429 227 0.169
regulation of cell differentiation GO:0045595 393 0.169
Fly
gtp catabolic process GO:0006184 237 0.168
regulation of gtp catabolic process GO:0033124 180 0.166
positive regulation of nucleotide catabolic process GO:0030813 185 0.165
ribonucleotide catabolic process GO:0009261 405 0.165
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.163
regulation of nucleotide metabolic process GO:0006140 269 0.161
positive regulation of nucleoside metabolic process GO:0045979 186 0.154
regulation of nucleoside metabolic process GO:0009118 209 0.145
positive regulation of cellular amine metabolic process GO:0033240 7 0.144
positive regulation of cellular catabolic process GO:0031331 284 0.144
ribonucleoside triphosphate metabolic process GO:0009199 412 0.140
purine ribonucleoside metabolic process GO:0046128 437 0.138
cellular response to endogenous stimulus GO:0071495 336 0.137
positive regulation of ras gtpase activity GO:0032320 117 0.135
positive regulation of protein phosphorylation GO:0001934 313 0.134
positive regulation of nucleotide metabolic process GO:0045981 230 0.128
regulation of small gtpase mediated signal transduction GO:0051056 156 0.127
regulation of rho gtpase activity GO:0032319 66 0.125
regulation of cell morphogenesis GO:0022604 153 0.117
negative regulation of cellular component organization GO:0051129 235 0.114
positive regulation of protein complex assembly GO:0031334 86 0.113
cellular amine metabolic process GO:0044106 41 0.113
regulation of nucleotide catabolic process GO:0030811 205 0.111
embryonic morphogenesis GO:0048598 85 0.111
asymmetric neuroblast division GO:0055059 1 0.107
positive regulation of gtpase activity GO:0043547 166 0.107
negative regulation of multicellular organismal process GO:0051241 317 0.105
neurogenesis GO:0022008 169 0.104
Fly
growth GO:0040007 202 0.104
positive regulation of gtp catabolic process GO:0033126 166 0.104
regulation of cell projection assembly GO:0060491 47 0.103
protein autophosphorylation GO:0046777 123 0.097
regulation of protein complex assembly GO:0043254 147 0.096
circulatory system development GO:0072359 262 0.095
positive regulation of cell projection organization GO:0031346 64 0.095
response to oxygen containing compound GO:1901700 369 0.094
small gtpase mediated signal transduction GO:0007264 78 0.094
positive regulation of protein polymerization GO:0032273 45 0.093
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.093
positive regulation of catabolic process GO:0009896 310 0.093
regulation of proteolysis GO:0030162 293 0.090
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.088
generation of neurons GO:0048699 152 0.088
Fly
neuronal stem cell division GO:0036445 1 0.087
regulation of ras gtpase activity GO:0032318 128 0.087
cellular ketone metabolic process GO:0042180 80 0.085
positive regulation of organelle organization GO:0010638 195 0.084
single organism cell adhesion GO:0098602 179 0.084
Fly
negative regulation of cell differentiation GO:0045596 171 0.083
peptidyl tyrosine phosphorylation GO:0018108 170 0.083
stem cell division GO:0017145 2 0.082
neuroblast division GO:0055057 1 0.080
positive regulation of phosphorylation GO:0042327 394 0.079
positive regulation of protein kinase activity GO:0045860 190 0.079
somatic stem cell division GO:0048103 1 0.078
cell part morphogenesis GO:0032990 137 0.076
ras protein signal transduction GO:0007265 73 0.076
regulation of cell cycle GO:0051726 393 0.074
positive regulation of mapk cascade GO:0043410 190 0.073
vesicle mediated transport GO:0016192 371 0.073
endocytosis GO:0006897 159 0.073
cellular macromolecular complex assembly GO:0034622 324 0.072
microtubule cytoskeleton organization GO:0000226 176 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
cell development GO:0048468 328 0.071
Fly
neural tube formation GO:0001841 3 0.070
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.070
positive regulation of rac gtpase activity GO:0032855 31 0.070
neuron development GO:0048666 113 0.069
Fly
regulation of cellular response to stress GO:0080135 244 0.069
protein modification by small protein conjugation GO:0032446 342 0.068
positive regulation of developmental process GO:0051094 314 0.067
Fly
activation of protein kinase activity GO:0032147 90 0.067
endomembrane system organization GO:0010256 196 0.067
Fly
positive regulation of cell death GO:0010942 263 0.066
cellular response to oxygen containing compound GO:1901701 276 0.066
embryonic epithelial tube formation GO:0001838 4 0.065
morphogenesis of embryonic epithelium GO:0016331 4 0.065
regulation of ras protein signal transduction GO:0046578 155 0.065
keratinization GO:0031424 2 0.064
cell growth GO:0016049 160 0.064
cell projection morphogenesis GO:0048858 129 0.063
neuroblast proliferation GO:0007405 4 0.063
mitotic cell cycle GO:0000278 326 0.061
regulation of nervous system development GO:0051960 88 0.059
Fly
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.059
Fly
asymmetric stem cell division GO:0098722 1 0.059
regulation of stress activated mapk cascade GO:0032872 84 0.059
tube development GO:0035295 125 0.057
cell cell adhesion mediated by cadherin GO:0044331 4 0.057
Fly
epidermal cell differentiation GO:0009913 45 0.056
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.056
embryo development GO:0009790 123 0.055
cellular amino acid metabolic process GO:0006520 116 0.055
positive regulation of jnk cascade GO:0046330 52 0.054
activation of mapkk activity GO:0000186 18 0.054
anatomical structure formation involved in morphogenesis GO:0048646 284 0.054
regulation of mitotic cell cycle GO:0007346 189 0.052
negative regulation of catalytic activity GO:0043086 335 0.052
response to wounding GO:0009611 168 0.051
positive regulation of transferase activity GO:0051347 227 0.051
apoptotic signaling pathway GO:0097190 268 0.050
microtubule based process GO:0007017 210 0.050
vacuole organization GO:0007033 44 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.049
regulation of jnk cascade GO:0046328 73 0.047
plasma membrane organization GO:0007009 115 0.047
regulation of vesicle mediated transport GO:0060627 130 0.046
peptidyl serine modification GO:0018209 106 0.046
Fly
mitotic cell cycle process GO:1903047 286 0.045
positive regulation of hydrolase activity GO:0051345 331 0.045
multicellular organismal aging GO:0010259 3 0.045
membrane organization GO:0061024 292 0.045
developmental growth GO:0048589 48 0.045
cellular response to nitrogen compound GO:1901699 144 0.045
negative regulation of protein metabolic process GO:0051248 391 0.044
amine metabolic process GO:0009308 44 0.044
spermatid differentiation GO:0048515 4 0.043
cellular response to calcium ion GO:0071277 19 0.043
cell division GO:0051301 168 0.043
regulation of cell development GO:0060284 161 0.043
Fly
cell adhesion GO:0007155 325 0.043
Fly
determination of adult lifespan GO:0008340 2 0.042
regulation of protein kinase activity GO:0045859 289 0.041
cell fate commitment GO:0045165 27 0.041
Fly
regulation of cell shape GO:0008360 48 0.041
positive regulation of apoptotic process GO:0043065 246 0.041
positive regulation of programmed cell death GO:0043068 249 0.041
memory GO:0007613 3 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.040
hemopoiesis GO:0030097 180 0.040
compound eye development GO:0048749 1 0.040
Fly
hair follicle morphogenesis GO:0031069 2 0.040
single organism cellular localization GO:1902580 332 0.039
cardiovascular system development GO:0072358 262 0.039
regulation of intracellular transport GO:0032386 195 0.039
axonogenesis GO:0007409 31 0.038
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
regulation of neurogenesis GO:0050767 82 0.037
Fly
vesicle organization GO:0016050 62 0.037
organelle localization GO:0051640 84 0.037
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.036
regulation of kinase activity GO:0043549 314 0.036
positive regulation of stress activated mapk cascade GO:0032874 60 0.036
cellular protein catabolic process GO:0044257 261 0.036
single organism membrane organization GO:0044802 268 0.035
negative regulation of growth GO:0045926 97 0.035
neuron fate commitment GO:0048663 2 0.035
chordate embryonic development GO:0043009 34 0.035
epithelial cell differentiation GO:0030855 141 0.035
regulation of cell migration GO:0030334 289 0.035
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.034
regulation of cell growth GO:0001558 135 0.033
secretion GO:0046903 254 0.033
regulation of synaptic plasticity GO:0048167 3 0.033
signal transduction by phosphorylation GO:0023014 297 0.033
jnk cascade GO:0007254 80 0.032
cellular response to abiotic stimulus GO:0071214 117 0.032
peptidyl tyrosine modification GO:0018212 170 0.032
positive regulation of kinase activity GO:0033674 204 0.031
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.031
cell fate determination GO:0001709 3 0.031
tube morphogenesis GO:0035239 95 0.031
establishment of organelle localization GO:0051656 59 0.031
nuclear import GO:0051170 106 0.031
single organism reproductive process GO:0044702 98 0.031
response to nitrogen compound GO:1901698 184 0.030
blood vessel morphogenesis GO:0048514 162 0.030
regulation of angiogenesis GO:0045765 92 0.029
response to organonitrogen compound GO:0010243 156 0.029
cell morphogenesis involved in differentiation GO:0000904 144 0.029
receptor mediated endocytosis GO:0006898 84 0.029
regulation of growth GO:0040008 165 0.029
positive regulation of locomotion GO:0040017 186 0.029
regulation of neuron differentiation GO:0045664 70 0.028
Fly
primary neural tube formation GO:0014020 3 0.028
lipid metabolic process GO:0006629 381 0.028
vasculature development GO:0001944 181 0.028
regulation of neuron projection development GO:0010975 57 0.027
regulation of cell motility GO:2000145 299 0.027
regulation of mapk cascade GO:0043408 262 0.027
segmentation GO:0035282 4 0.027
regulation of protein binding GO:0043393 66 0.027
protein ubiquitination GO:0016567 314 0.027
regulation of neural precursor cell proliferation GO:2000177 4 0.027
cell substrate adhesion GO:0031589 132 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
cell projection assembly GO:0030031 126 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.026
protein localization to organelle GO:0033365 280 0.026
establishment or maintenance of neuroblast polarity GO:0045196 1 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
golgi organization GO:0007030 38 0.025
Fly
dendritic spine morphogenesis GO:0060997 3 0.025
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
single organism nuclear import GO:1902593 104 0.025
positive regulation of map kinase activity GO:0043406 80 0.025
cell type specific apoptotic process GO:0097285 125 0.025
regulation of protein targeting GO:1903533 91 0.025
negative regulation of organelle organization GO:0010639 126 0.025
response to abiotic stimulus GO:0009628 336 0.025
response to other organism GO:0051707 261 0.024
locomotory behavior GO:0007626 1 0.024
mitotic nuclear division GO:0007067 119 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
tissue morphogenesis GO:0048729 96 0.024
protein localization to membrane GO:0072657 160 0.024
neuron projection morphogenesis GO:0048812 50 0.023
regulation of protein catabolic process GO:0042176 155 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
negative regulation of cellular catabolic process GO:0031330 83 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of protein import into nucleus GO:0042306 78 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
epidermis development GO:0008544 59 0.022
positive regulation of jun kinase activity GO:0043507 23 0.022
cdc42 protein signal transduction GO:0032488 4 0.022
regulation of protein localization GO:0032880 296 0.022
cellular response to peptide GO:1901653 59 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
regulation of cellular protein catabolic process GO:1903362 96 0.021
establishment of protein localization to membrane GO:0090150 121 0.021
protein catabolic process GO:0030163 325 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
amide transport GO:0042886 76 0.021
axon development GO:0061564 34 0.021
spermatid development GO:0007286 4 0.021
regulation of protein maturation GO:1903317 150 0.021
morphogenesis of an epithelium GO:0002009 60 0.021
central nervous system development GO:0007417 123 0.021
Fly
establishment of protein localization to plasma membrane GO:0090002 68 0.020
regulation of microtubule based process GO:0032886 74 0.020
actin nucleation GO:0045010 21 0.020
wnt signaling pathway GO:0016055 156 0.020
regulation of protein processing GO:0070613 150 0.020
epidermis morphogenesis GO:0048730 3 0.020
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
anterior posterior axis specification GO:0009948 2 0.020
skin development GO:0043588 76 0.020
collateral sprouting GO:0048668 2 0.020
negative regulation of actin nucleation GO:0051126 3 0.020
biological adhesion GO:0022610 331 0.019
Fly
response to organic cyclic compound GO:0014070 204 0.019
sex differentiation GO:0007548 45 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
autophagy GO:0006914 88 0.019
sterol transport GO:0015918 39 0.019
epithelial cell migration GO:0010631 119 0.019
regulation of cell cycle process GO:0010564 266 0.019
protein maturation GO:0051604 233 0.019
regulation of peroxidase activity GO:2000468 2 0.019
maintenance of location GO:0051235 112 0.019
dephosphorylation GO:0016311 209 0.018
establishment of vesicle localization GO:0051650 23 0.018
cellular response to metal ion GO:0071248 43 0.018
activation of mapk activity GO:0000187 45 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
protein processing GO:0016485 226 0.018
protein import GO:0017038 130 0.018
protein localization to plasma membrane GO:0072659 93 0.018
tissue migration GO:0090130 119 0.018
monocarboxylic acid metabolic process GO:0032787 185 0.018
negative regulation of protein kinase activity GO:0006469 98 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
cytokinesis GO:0000910 96 0.018
rna processing GO:0006396 255 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.018
protein targeting to nucleus GO:0044744 104 0.018
reproductive process GO:0022414 106 0.018
blood circulation GO:0008015 113 0.018
negative regulation of catabolic process GO:0009895 104 0.018
somatic muscle development GO:0007525 1 0.017
regionalization GO:0003002 29 0.017
endothelial cell migration GO:0043542 86 0.017
mitochondrion organization GO:0007005 156 0.017
meiosis i GO:0007127 4 0.017
response to hormone GO:0009725 175 0.017
stress activated mapk cascade GO:0051403 93 0.017
response to growth factor GO:0070848 205 0.017
positive regulation of transport GO:0051050 336 0.017
muscle structure development GO:0061061 98 0.017
response to activity GO:0014823 0 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
somatic stem cell maintenance GO:0035019 4 0.017
cilium organization GO:0044782 68 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
developmental cell growth GO:0048588 18 0.016
regulation of locomotion GO:0040012 329 0.016
positive regulation of epithelial cell migration GO:0010634 55 0.016
cytoplasmic transport GO:0016482 379 0.016
response to peptide hormone GO:0043434 61 0.016
stem cell differentiation GO:0048863 93 0.016
membrane budding GO:0006900 28 0.016
axon cargo transport GO:0008088 2 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
regulation of vasculature development GO:1901342 97 0.016
regulation of protein ubiquitination GO:0031396 95 0.015
atp metabolic process GO:0046034 176 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
negative regulation of protein processing GO:0010955 142 0.015
nucleus localization GO:0051647 1 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
regulation of microtubule cytoskeleton organization GO:0070507 61 0.015
negative regulation of cytoskeleton organization GO:0051494 45 0.015
negative regulation of cell cycle GO:0045786 193 0.015
lipid localization GO:0010876 106 0.015
retinal ganglion cell axon guidance GO:0031290 2 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
cell cycle phase transition GO:0044770 173 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
gastrulation GO:0007369 51 0.015
positive regulation of neuron death GO:1901216 14 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
arp2 3 complex mediated actin nucleation GO:0034314 17 0.015
positive regulation of protein transport GO:0051222 135 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
leukocyte migration GO:0050900 107 0.014
activation of mapkkk activity GO:0000185 7 0.014
regulation of cell substrate adhesion GO:0010810 68 0.014
cardiac conduction system development GO:0003161 2 0.014
brain development GO:0007420 97 0.014
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
negative regulation of cell size GO:0045792 3 0.014
Fly
cloaca development GO:0035844 1 0.014
nuclear transport GO:0051169 179 0.014
developmental process involved in reproduction GO:0003006 66 0.014
negative regulation of vasculature development GO:1901343 43 0.014
positive regulation of cell motility GO:2000147 177 0.014
negative regulation of actin filament polymerization GO:0030837 10 0.014
regulation of actin nucleation GO:0051125 10 0.014
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.014
lipid transport GO:0006869 90 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
negative regulation of locomotion GO:0040013 118 0.014
regulation of ion transport GO:0043269 189 0.014
positive regulation of cell migration GO:0030335 172 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
neural crest cell development GO:0014032 3 0.013
regulation of cellular component movement GO:0051270 334 0.013
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
mapk cascade GO:0000165 288 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
epithelial cell fate commitment GO:0072148 3 0.013
regulation of protein localization to plasma membrane GO:1903076 40 0.013
regulation of autophagy GO:0010506 52 0.013
ectodermal placode development GO:0071696 1 0.013
regulation of stress fiber assembly GO:0051492 32 0.013
regulation of jun kinase activity GO:0043506 27 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
regulation of collateral sprouting GO:0048670 2 0.013
actin filament bundle assembly GO:0051017 54 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
meiotic chromosome segregation GO:0045132 4 0.013
establishment of neuroblast polarity GO:0045200 1 0.013
negative regulation of proteolysis GO:0045861 132 0.013
activation of jnkk activity GO:0007256 1 0.013
ribonucleotide biosynthetic process GO:0009260 81 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
Fly
negative regulation of cell migration GO:0030336 102 0.013
response to increased oxygen levels GO:0036296 4 0.013
lamellipodium organization GO:0097581 30 0.013
translation GO:0006412 132 0.013
developmental growth involved in morphogenesis GO:0060560 23 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
peptidyl threonine modification GO:0018210 45 0.012
positive regulation of actin filament bundle assembly GO:0032233 25 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
activation of cdc42 gtpase activity GO:0032864 2 0.012
organ morphogenesis GO:0009887 147 0.012
Fly
response to hyperoxia GO:0055093 4 0.012
epithelium migration GO:0090132 119 0.012
negative regulation of protein maturation GO:1903318 142 0.012
positive regulation of protein import into nucleus GO:0042307 46 0.012
organelle inheritance GO:0048308 2 0.012
blood vessel development GO:0001568 172 0.012
cilium morphogenesis GO:0060271 75 0.012
positive regulation of cell cycle GO:0045787 140 0.012
macroautophagy GO:0016236 39 0.012
skeletal muscle organ development GO:0060538 26 0.012
positive regulation of cell development GO:0010720 92 0.012
Fly
thrombin receptor signaling pathway GO:0070493 5 0.012
reproduction GO:0000003 63 0.012
negative regulation of endothelial cell migration GO:0010596 29 0.012
cellular response to tumor necrosis factor GO:0071356 63 0.012
regulation of map kinase activity GO:0043405 108 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
rna splicing GO:0008380 131 0.012
response to peptide GO:1901652 65 0.012
response to calcium ion GO:0051592 46 0.012
peptide secretion GO:0002790 51 0.012
response to acid chemical GO:0001101 66 0.012
regulation of rna splicing GO:0043484 62 0.012
protein homooligomerization GO:0051260 100 0.011
positive regulation of neurogenesis GO:0050769 49 0.011
Fly
intracellular receptor signaling pathway GO:0030522 104 0.011
intracellular protein transport GO:0006886 270 0.011
negative regulation of cell death GO:0060548 345 0.011
regulation of developmental growth GO:0048638 30 0.011
system process GO:0003008 349 0.011
regulation of synapse structural plasticity GO:0051823 2 0.011
peptide transport GO:0015833 74 0.011
regulation of peptidyl serine phosphorylation GO:0033135 50 0.011
negative regulation of epithelial cell migration GO:0010633 38 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
golgi vesicle transport GO:0048193 80 0.011
regulation of axonogenesis GO:0050770 16 0.011
oogenesis GO:0048477 2 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of cardioblast differentiation GO:0051890 4 0.011
neural tube patterning GO:0021532 2 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
organic anion transport GO:0015711 103 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
negative regulation of blood vessel morphogenesis GO:2000181 41 0.011
oocyte development GO:0048599 1 0.011

PAK4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.016
musculoskeletal system disease DOID:17 223 0.011