Homo sapiens

142 known processes

CHD6

chromodomain helicase DNA binding protein 6

(Aliases: RIGB,CHD5,KIAA1335)

CHD6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 2 0.243
Fly
cellular macromolecular complex assembly GO:0034622 324 0.137
multicellular organismal aging GO:0010259 3 0.135
Fly
cellular protein complex assembly GO:0043623 188 0.114
cell fate determination GO:0001709 3 0.103
female gamete generation GO:0007292 2 0.084
Fly
post embryonic development GO:0009791 2 0.084
Fly
protein localization to organelle GO:0033365 280 0.058
cytoplasmic transport GO:0016482 379 0.058
chromatin organization GO:0006325 351 0.057
Human
embryonic epithelial tube formation GO:0001838 4 0.054
stem cell division GO:0017145 2 0.053
insemination GO:0007320 1 0.050
cellular amino acid metabolic process GO:0006520 116 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.047
intracellular protein transport GO:0006886 270 0.047
single organism nuclear import GO:1902593 104 0.045
amine metabolic process GO:0009308 44 0.045
nucleoside catabolic process GO:0009164 408 0.045
asymmetric stem cell division GO:0098722 1 0.043
lysosomal transport GO:0007041 33 0.043
protein localization to nucleus GO:0034504 136 0.041
protein import GO:0017038 130 0.040
anterior posterior axis specification GO:0009948 2 0.039
protein targeting to nucleus GO:0044744 104 0.039
cell division GO:0051301 168 0.038
single organism cellular localization GO:1902580 332 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
cellular response to growth factor stimulus GO:0071363 197 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.035
ras protein signal transduction GO:0007265 73 0.035
nuclear import GO:0051170 106 0.035
segmentation GO:0035282 4 0.035
Fly
regulation of cellular response to stress GO:0080135 244 0.034
enzyme linked receptor protein signaling pathway GO:0007167 303 0.033
cellular macromolecule catabolic process GO:0044265 380 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
dephosphorylation GO:0016311 209 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
nervous system development GO:0007399 293 0.032
Human Fly
protein targeting GO:0006605 187 0.031
protein modification by small protein conjugation GO:0032446 342 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
ribonucleotide catabolic process GO:0009261 405 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
protein ubiquitination GO:0016567 314 0.029
organophosphate catabolic process GO:0046434 430 0.029
nucleotide catabolic process GO:0009166 408 0.029
metal ion transport GO:0030001 272 0.028
protein import into nucleus GO:0006606 104 0.028
cellular ketone metabolic process GO:0042180 80 0.028
locomotory behavior GO:0007626 1 0.028
endosomal transport GO:0016197 129 0.028
cellular amine metabolic process GO:0044106 41 0.028
positive regulation of transport GO:0051050 336 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
nucleocytoplasmic transport GO:0006913 176 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
neural tube formation GO:0001841 3 0.027
regulation of cell cycle GO:0051726 393 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
modification dependent protein catabolic process GO:0019941 209 0.027
mating GO:0007618 1 0.026
cellular component morphogenesis GO:0032989 314 0.026
Fly
protein catabolic process GO:0030163 325 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
mitotic cell cycle GO:0000278 326 0.025
regulation of transferase activity GO:0051338 355 0.025
chromatin modification GO:0016568 298 0.025
Human
purine containing compound catabolic process GO:0072523 411 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
cell projection organization GO:0030030 252 0.024
Fly
positive regulation of kinase activity GO:0033674 204 0.024
peptidyl lysine modification GO:0018205 144 0.024
regulation of cellular component biogenesis GO:0044087 281 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
nuclear transport GO:0051169 179 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
regulation of kinase activity GO:0043549 314 0.022
transmembrane transport GO:0055085 399 0.022
lens development in camera type eye GO:0002088 2 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
organ formation GO:0048645 3 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
single organism membrane organization GO:0044802 268 0.022
photoreceptor cell differentiation GO:0046530 2 0.022
covalent chromatin modification GO:0016569 254 0.022
memory GO:0007613 3 0.021
Fly
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
cell development GO:0048468 328 0.021
Fly
calcium ion transport GO:0006816 147 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
regulation of mitosis GO:0007088 63 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
neurological system process GO:0050877 163 0.021
Human Fly
regulation of cytoplasmic transport GO:1903649 149 0.021
response to growth factor GO:0070848 205 0.021
regulation of canonical wnt signaling pathway GO:0060828 88 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.020
membrane organization GO:0061024 292 0.020
positive regulation of developmental process GO:0051094 314 0.020
Fly
defense response GO:0006952 315 0.020
negative regulation of cell death GO:0060548 345 0.020
positive regulation of gtpase activity GO:0043547 166 0.020
notch signaling pathway GO:0007219 31 0.020
adult locomotory behavior GO:0008344 1 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
mapk cascade GO:0000165 288 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
neural tube patterning GO:0021532 2 0.020
cellular homeostasis GO:0019725 196 0.019
negative regulation of glomerulus development GO:0090194 2 0.019
lipid metabolic process GO:0006629 381 0.019
divalent inorganic cation transport GO:0072511 158 0.019
heart formation GO:0060914 2 0.019
regulation of cell cycle process GO:0010564 266 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
renal system pattern specification GO:0072048 1 0.019
microtubule based process GO:0007017 210 0.019
positive regulation of protein transport GO:0051222 135 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
Human
innate immune response GO:0045087 178 0.019
cellular protein catabolic process GO:0044257 261 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.018
response to oxygen containing compound GO:1901700 369 0.018
negative regulation of protein modification process GO:0031400 200 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
homeostasis of number of cells GO:0048872 40 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
Human
negative regulation of cell cycle GO:0045786 193 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
negative regulation of kidney development GO:0090185 2 0.018
neuromuscular junction development GO:0007528 3 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
hindbrain development GO:0030902 3 0.017
secretion GO:0046903 254 0.017
Human
negative regulation of cell fate commitment GO:0010454 3 0.017
negative regulation of wnt signaling pathway GO:0030178 69 0.017
Human
oogenesis GO:0048477 2 0.017
Fly
regulation of mitotic cell cycle GO:0007346 189 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
chemical homeostasis GO:0048878 306 0.017
divalent metal ion transport GO:0070838 152 0.017
regulation of dephosphorylation GO:0035303 96 0.017
histone modification GO:0016570 251 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
protein acylation GO:0043543 138 0.017
lung alveolus development GO:0048286 4 0.017
organelle assembly GO:0070925 176 0.017
regulation of cell morphogenesis GO:0022604 153 0.016
response to abiotic stimulus GO:0009628 336 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
immune response GO:0006955 307 0.016
Fly
guanosine containing compound catabolic process GO:1901069 239 0.016
smad protein import into nucleus GO:0007184 13 0.016
regulation of dna metabolic process GO:0051052 153 0.016
protein maturation GO:0051604 233 0.016
cell projection assembly GO:0030031 126 0.016
cell projection morphogenesis GO:0048858 129 0.016
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
copulation GO:0007620 1 0.016
cation transmembrane transport GO:0098655 238 0.016
regulation of mapk cascade GO:0043408 262 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
cerebellum development GO:0021549 2 0.016
specification of organ identity GO:0010092 3 0.016
growth GO:0040007 202 0.016
Fly
carbohydrate metabolic process GO:0005975 207 0.016
metencephalon development GO:0022037 2 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
endodermal cell fate commitment GO:0001711 4 0.016
regulation of actin filament based process GO:0032970 141 0.016
regulation of cell adhesion GO:0030155 166 0.016
regulation of cellular component movement GO:0051270 334 0.016
negative regulation of developmental process GO:0051093 247 0.016
cell part morphogenesis GO:0032990 137 0.016
Fly
regulation of protein kinase activity GO:0045859 289 0.016
regeneration GO:0031099 4 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of cell differentiation GO:0045595 393 0.015
positive regulation of cell motility GO:2000147 177 0.015
positive regulation of transferase activity GO:0051347 227 0.015
regulation of cell development GO:0060284 161 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
regulation of protein catabolic process GO:0042176 155 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
gtp catabolic process GO:0006184 237 0.015
mitotic cell cycle process GO:1903047 286 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
metal ion homeostasis GO:0055065 169 0.015
response to transforming growth factor beta GO:0071559 94 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
cellular chemical homeostasis GO:0055082 180 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
blastoderm segmentation GO:0007350 2 0.015
Fly
vesicle mediated transport GO:0016192 371 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of cell motility GO:2000145 299 0.015
nitrogen compound transport GO:0071705 191 0.015
Human
cell morphogenesis GO:0000902 296 0.015
Fly
system process GO:0003008 349 0.015
Human Fly
regulation of phosphatase activity GO:0010921 81 0.014
regulation of response to external stimulus GO:0032101 222 0.014
gtp metabolic process GO:0046039 239 0.014
organ morphogenesis GO:0009887 147 0.014
Human Fly
positive regulation of intracellular transport GO:0032388 104 0.014
hemopoiesis GO:0030097 180 0.014
Human
ribonucleoside catabolic process GO:0042454 406 0.014
endocytosis GO:0006897 159 0.014
cellular cation homeostasis GO:0030003 163 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
stem cell differentiation GO:0048863 93 0.014
protein processing GO:0016485 226 0.014
heart field specification GO:0003128 2 0.014
actin filament based process GO:0030029 224 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
regulation of membrane potential GO:0042391 95 0.014
negative regulation of organelle organization GO:0010639 126 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
rho protein signal transduction GO:0007266 26 0.014
regulation of vesicle mediated transport GO:0060627 130 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of gtpase activity GO:0043087 180 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cation homeostasis GO:0055080 189 0.013
regulation of notch signaling pathway GO:0008593 18 0.013
rhythmic behavior GO:0007622 2 0.013
dna repair GO:0006281 198 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
protein acetylation GO:0006473 116 0.013
regulation of defense response GO:0031347 154 0.013
generation of neurons GO:0048699 152 0.013
Fly
negative regulation of hydrolase activity GO:0051346 182 0.013
cell cycle phase transition GO:0044770 173 0.013
apoptotic signaling pathway GO:0097190 268 0.013
regulation of locomotion GO:0040012 329 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.012
neuroblast proliferation GO:0007405 4 0.012
associative learning GO:0008306 1 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
epithelial cell proliferation GO:0050673 128 0.012
pericardium development GO:0060039 2 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
receptor metabolic process GO:0043112 81 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
compound eye development GO:0048749 1 0.012
endochondral bone morphogenesis GO:0060350 3 0.012
visual behavior GO:0007632 2 0.012
regulation of protein complex assembly GO:0043254 147 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
regulation of protein maturation GO:1903317 150 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
positive regulation of cell death GO:0010942 263 0.012
positive regulation of locomotion GO:0040017 186 0.012
negative regulation of transferase activity GO:0051348 124 0.012
ameboidal type cell migration GO:0001667 135 0.012
Fly
dna replication GO:0006260 116 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
negative regulation of gliogenesis GO:0014014 3 0.012
regulation of ras gtpase activity GO:0032318 128 0.011
response to inorganic substance GO:0010035 127 0.011
tube development GO:0035295 125 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
negative regulation of proteolysis GO:0045861 132 0.011
detection of stimulus GO:0051606 85 0.011
regulation of cell migration GO:0030334 289 0.011
regulation of proteolysis GO:0030162 293 0.011
spermatid development GO:0007286 4 0.011
axis elongation GO:0003401 4 0.011
taxis GO:0042330 157 0.011
Fly
bmp signaling pathway involved in heart development GO:0061312 3 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
negative regulation of protein processing GO:0010955 142 0.011
single organism reproductive process GO:0044702 98 0.011
Human Fly
positive regulation of cytoplasmic transport GO:1903651 82 0.011
autophagy GO:0006914 88 0.011
glycoprotein metabolic process GO:0009100 110 0.011
tripartite regional subdivision GO:0007351 2 0.011
positive regulation of catabolic process GO:0009896 310 0.011
cilium organization GO:0044782 68 0.011
stress activated mapk cascade GO:0051403 93 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
aging GO:0007568 66 0.011
Fly
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of binding GO:0051098 111 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
response to biotic stimulus GO:0009607 276 0.011
Fly
inner ear morphogenesis GO:0042472 4 0.011
Human
embryo development GO:0009790 123 0.011
Human Fly
mitotic nuclear division GO:0007067 119 0.011
visual learning GO:0008542 1 0.011
regulation of protein processing GO:0070613 150 0.011
sensory perception of pain GO:0019233 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
myeloid cell differentiation GO:0030099 117 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
positive regulation of protein localization to nucleus GO:1900182 48 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
macromolecule methylation GO:0043414 97 0.011
calcium ion transmembrane transport GO:0070588 76 0.011
epithelium development GO:0060429 227 0.011
Fly
negative regulation of mitotic cell cycle GO:0045930 102 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
protein autophosphorylation GO:0046777 123 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
Fly
organelle localization GO:0051640 84 0.011
meiotic chromosome segregation GO:0045132 4 0.011
cellular lipid metabolic process GO:0044255 303 0.011
chemotaxis GO:0006935 157 0.011
Fly
oocyte development GO:0048599 1 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
single organism cell adhesion GO:0098602 179 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
developmental programmed cell death GO:0010623 3 0.010
nerve development GO:0021675 4 0.010
Human
endomembrane system organization GO:0010256 196 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010
biological adhesion GO:0022610 331 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
cilium morphogenesis GO:0060271 75 0.010
long term memory GO:0007616 2 0.010
protein dephosphorylation GO:0006470 81 0.010
eye development GO:0001654 42 0.010
Human
negative regulation of response to external stimulus GO:0032102 83 0.010
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
maintenance of location GO:0051235 112 0.010
central nervous system development GO:0007417 123 0.010
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
epithelial cell differentiation GO:0030855 141 0.010
Fly
histone acetylation GO:0016573 93 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
positive regulation of organelle organization GO:0010638 195 0.010
cell growth GO:0016049 160 0.010

CHD6 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.050
nervous system disease DOID:863 431 0.050
sensory system disease DOID:0050155 203 0.045
eye and adnexa disease DOID:1492 150 0.045
eye disease DOID:5614 149 0.045
disease of metabolism DOID:0014667 295 0.018
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
inherited metabolic disorder DOID:655 242 0.011
musculoskeletal system disease DOID:17 223 0.010
connective tissue disease DOID:65 109 0.010
neurodegenerative disease DOID:1289 102 0.010
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010
immune system disease DOID:2914 155 0.010