|
|
immune response
|
GO:0006955 |
307 |
0.474
|
Human Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.444
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.421
|
Human Zebrafish |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.421
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.397
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.339
|
Human |
|
|
wound healing
|
GO:0042060 |
115 |
0.319
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.289
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.289
|
Human Mouse Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.271
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.259
|
Human Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.249
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.247
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.247
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.237
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.233
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.225
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.221
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.220
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.218
|
Zebrafish Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.216
|
Human Zebrafish |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.213
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.202
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.201
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.194
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.190
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.182
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.181
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.181
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.177
|
Human Mouse Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.169
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.165
|
Human Fly |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.163
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.162
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.161
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.161
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.152
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.149
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.146
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.145
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.143
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.143
|
Human Zebrafish Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.143
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.140
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.137
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.137
|
Human |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.135
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.133
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.131
|
Human Mouse |
|
|
response to lipid
|
GO:0033993 |
206 |
0.129
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.129
|
Human Zebrafish |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.127
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.122
|
Human Zebrafish |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.120
|
Mouse Fly |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.119
|
Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.119
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.118
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.117
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.115
|
Human Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.112
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.112
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.111
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.111
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.108
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.107
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.106
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.103
|
Human Mouse Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.103
|
Human Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.101
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.100
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.100
|
Human |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.100
|
Human Zebrafish |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.100
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.100
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.100
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.099
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.098
|
Human Rat Fly |
|
|
coagulation
|
GO:0050817 |
78 |
0.098
|
Human |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.096
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.095
|
|
|
|
system process
|
GO:0003008 |
349 |
0.095
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.095
|
Human Zebrafish |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.094
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.094
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.092
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.091
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.091
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.091
|
Human Zebrafish Mouse |
|
|
positive regulation of aldosterone secretion
|
GO:2000860 |
1 |
0.090
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.088
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.087
|
Human Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.086
|
Zebrafish Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.086
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.084
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.083
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.083
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.082
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.079
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.078
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.078
|
Human Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.078
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.077
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.077
|
Human Zebrafish |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.077
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.075
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.074
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.073
|
|
|
|
aldosterone secretion
|
GO:0035932 |
1 |
0.072
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.071
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.071
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.071
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.071
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.070
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.069
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.068
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.067
|
Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.066
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.065
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.064
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.064
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.063
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.062
|
Human Zebrafish Rat |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.062
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.062
|
Fly |
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.061
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.060
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.059
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.058
|
Zebrafish |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.058
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.058
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.058
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.057
|
Human Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.057
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.057
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.056
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.056
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.055
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.055
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.055
|
Human |
|
|
positive regulation of renal albumin absorption
|
GO:2000534 |
1 |
0.054
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.054
|
Zebrafish |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.054
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.054
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.054
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.054
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.054
|
Human |
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.053
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.053
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.052
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.051
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.051
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.051
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.050
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.050
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.050
|
Zebrafish |
|
|
inflammatory response
|
GO:0006954 |
79 |
0.049
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.049
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.049
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.049
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.049
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.048
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.048
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.048
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.047
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.047
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.047
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.047
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.047
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.047
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.046
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.046
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.046
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.046
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.046
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.046
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.046
|
|
|
|
positive regulation of mineralocorticoid secretion
|
GO:2000857 |
1 |
0.045
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.045
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.044
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.044
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.043
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.043
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.043
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.043
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.042
|
Human Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.042
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.042
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.041
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.041
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.041
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.040
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.040
|
Human |
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.040
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.040
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.040
|
Human Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.040
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.040
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.039
|
Rat |
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.039
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.039
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.039
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.039
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.039
|
Mouse |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.039
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.038
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.038
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.038
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.038
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.038
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.038
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.038
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.038
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.037
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.037
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.036
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.036
|
Human Zebrafish |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.036
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.036
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.035
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.035
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.035
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.035
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.035
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.035
|
Human |
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.035
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.035
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.035
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.034
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.034
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.034
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.034
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.034
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.034
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.034
|
Zebrafish Rat |
|
|
ossification
|
GO:0001503 |
121 |
0.034
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.034
|
Human Fly |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.034
|
|
|
|
positive regulation of steroid hormone secretion
|
GO:2000833 |
6 |
0.033
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.033
|
Human |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.033
|
Human Zebrafish |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.033
|
Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.033
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.033
|
Rat |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.033
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.032
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.032
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.032
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.032
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.032
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.032
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.031
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
1 |
0.031
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.031
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.031
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.031
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.031
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.031
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.031
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.031
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.030
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.030
|
Fly |
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.030
|
Zebrafish |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.030
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.030
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.030
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.030
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.030
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.029
|
Human |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.029
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.029
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.029
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.029
|
Human |
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.028
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.028
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.028
|
Human Fly |
|
|
chemokine production
|
GO:0032602 |
32 |
0.028
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.028
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.028
|
Human Zebrafish |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.028
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.028
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.027
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.027
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.027
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.027
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.027
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.027
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.027
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.027
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.027
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.027
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.026
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.026
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.026
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.026
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.026
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.026
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.026
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.026
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.026
|
Human Mouse Fly |
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.026
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.026
|
Human |
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.026
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.026
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.026
|
Human Zebrafish |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.026
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.026
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.026
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.025
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.025
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.025
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.025
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.025
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.025
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.025
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.025
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.025
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.024
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.024
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
4 |
0.024
|
|
|
|
complement component c5a signaling pathway
|
GO:0038178 |
1 |
0.024
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.024
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.024
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.024
|
|
|
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.024
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.023
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.023
|
Fly |
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.023
|
Rat |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.023
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.023
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.023
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.023
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.023
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.023
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.023
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.022
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.022
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.022
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.022
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.022
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.022
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.022
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.022
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.022
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.021
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.021
|
Human |
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
4 |
0.021
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.021
|
Human Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.021
|
|
|
|
growth
|
GO:0040007 |
202 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.021
|
Rat |
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.021
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.021
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.021
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.021
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.021
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.021
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.021
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.021
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.021
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.021
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.021
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.021
|
Human |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.021
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.021
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.020
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.020
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.020
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.020
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.020
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.020
|
Human Mouse Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.020
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.020
|
Rat |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.020
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.020
|
Fly |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.020
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.020
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.020
|
Fly |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.020
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.020
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.019
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.019
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.019
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.019
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.019
|
Zebrafish Mouse Rat |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.019
|
Human Mouse |
|
|
lipid modification
|
GO:0030258 |
84 |
0.019
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.019
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.019
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.019
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.019
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.018
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.018
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.018
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.018
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.018
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.018
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.018
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.018
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.018
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.018
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.018
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.018
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.018
|
Zebrafish Mouse Rat |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.018
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.018
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.017
|
Human |
|
|
signal release
|
GO:0023061 |
70 |
0.017
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.017
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.017
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.017
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.017
|
Zebrafish |
|
|
memory
|
GO:0007613 |
3 |
0.017
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.017
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.017
|
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
1 |
0.017
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.017
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.017
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.017
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.017
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.017
|
Fly |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.017
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.017
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.017
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.017
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.017
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.017
|
Human |
|
|
renal albumin absorption
|
GO:0097018 |
1 |
0.017
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.016
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.016
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.016
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.016
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.016
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.016
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.016
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.016
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.016
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.016
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.016
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
4 |
0.016
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.016
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.016
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.016
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.016
|
Human Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.016
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.016
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.016
|
Human |
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.016
|
Zebrafish |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.015
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.015
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.015
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.015
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.015
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.015
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.015
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.015
|
Human Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.015
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.015
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.015
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.015
|
Human |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.015
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.015
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.015
|
|
|
|
positive regulation of corticosteroid hormone secretion
|
GO:2000848 |
5 |
0.015
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.015
|
Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.015
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.015
|
Human Mouse |
|
|
response to peptide
|
GO:1901652 |
65 |
0.015
|
Fly |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.015
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.015
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.014
|
|
