Homo sapiens

46 known processes

FBXW5

F-box and WD repeat domain containing 5

(Aliases: RP11-229P13.10,MGC20962,DKFZp434B205,Fbw5)

FBXW5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of camp mediated signaling GO:0043951 4 0.612
proteasomal protein catabolic process GO:0010498 176 0.404
protein modification by small protein conjugation GO:0032446 342 0.383
cellular protein catabolic process GO:0044257 261 0.358
modification dependent macromolecule catabolic process GO:0043632 212 0.318
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.301
cellular macromolecule catabolic process GO:0044265 380 0.286
ubiquitin dependent protein catabolic process GO:0006511 206 0.283
modification dependent protein catabolic process GO:0019941 209 0.250
protein polyubiquitination GO:0000209 110 0.244
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.234
protein ubiquitination GO:0016567 314 0.214
protein catabolic process GO:0030163 325 0.208
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.119
cyclic nucleotide mediated signaling GO:0019935 26 0.075
camp mediated signaling GO:0019933 23 0.067
determination of adult lifespan GO:0008340 2 0.065
mitotic cell cycle process GO:1903047 286 0.061
Mouse
nervous system development GO:0007399 293 0.051
protein k48 linked ubiquitination GO:0070936 38 0.051
positive regulation of cellular amine metabolic process GO:0033240 7 0.048
cellular amine metabolic process GO:0044106 41 0.046
vesicle mediated transport GO:0016192 371 0.042
regulation of camp mediated signaling GO:0043949 13 0.042
protein monoubiquitination GO:0006513 39 0.041
mitotic cell cycle GO:0000278 326 0.038
Mouse
amine metabolic process GO:0009308 44 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
cellular lipid metabolic process GO:0044255 303 0.037
second messenger mediated signaling GO:0019932 78 0.035
neuromuscular junction development GO:0007528 3 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
multicellular organismal aging GO:0010259 3 0.033
negative regulation of intracellular signal transduction GO:1902532 183 0.032
negative regulation of catalytic activity GO:0043086 335 0.031
segmentation GO:0035282 4 0.031
positive regulation of catabolic process GO:0009896 310 0.031
Fly
regulation of kinase activity GO:0043549 314 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.028
regulation of triglyceride metabolic process GO:0090207 11 0.028
cellular ketone metabolic process GO:0042180 80 0.028
lipid metabolic process GO:0006629 381 0.025
hindbrain development GO:0030902 3 0.025
chemical homeostasis GO:0048878 306 0.024
regulation of proteolysis GO:0030162 293 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
metencephalon development GO:0022037 2 0.023
somatic muscle development GO:0007525 1 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
post embryonic development GO:0009791 2 0.022
cell growth GO:0016049 160 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
blood vessel morphogenesis GO:0048514 162 0.021
positive regulation of transferase activity GO:0051347 227 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
response to oxygen containing compound GO:1901700 369 0.020
locomotory behavior GO:0007626 1 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.019
regulation of transferase activity GO:0051338 355 0.019
cerebellum development GO:0021549 2 0.019
mapk cascade GO:0000165 288 0.019
cell morphogenesis GO:0000902 296 0.019
lipid biosynthetic process GO:0008610 177 0.018
regulation of protein stability GO:0031647 87 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
neurogenesis GO:0022008 169 0.018
response to nitrogen compound GO:1901698 184 0.018
response to abiotic stimulus GO:0009628 336 0.018
negative regulation of developmental process GO:0051093 247 0.018
transmembrane transport GO:0055085 399 0.017
regulation of mapk cascade GO:0043408 262 0.017
mitotic nuclear division GO:0007067 119 0.017
Mouse
organonitrogen compound biosynthetic process GO:1901566 200 0.017
growth GO:0040007 202 0.017
regulation of protein kinase activity GO:0045859 289 0.017
defense response GO:0006952 315 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of cellular response to stress GO:0080135 244 0.017
regulation of endopeptidase activity GO:0052548 170 0.016
regulation of peptidase activity GO:0052547 180 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.016
mitochondrion organization GO:0007005 156 0.016
protein processing GO:0016485 226 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
tor signaling GO:0031929 39 0.016
female gamete generation GO:0007292 2 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.015
positive regulation of cell death GO:0010942 263 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
organelle fission GO:0048285 149 0.015
Mouse
vasculature development GO:0001944 181 0.015
lipid localization GO:0010876 106 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
blastoderm segmentation GO:0007350 2 0.015
regulation of protein catabolic process GO:0042176 155 0.014
Fly
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
cellular lipid catabolic process GO:0044242 65 0.014
glycerolipid biosynthetic process GO:0045017 51 0.014
oxidation reduction process GO:0055114 396 0.014
negative regulation of cell cycle GO:0045786 193 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
response to organonitrogen compound GO:0010243 156 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
regeneration GO:0031099 4 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
system process GO:0003008 349 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
cardiovascular system development GO:0072358 262 0.014
regulation of cell cycle phase transition GO:1901987 126 0.013
metal ion transport GO:0030001 272 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
response to fungus GO:0009620 4 0.013
microtubule based process GO:0007017 210 0.013
negative regulation of cell death GO:0060548 345 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
protein maturation GO:0051604 233 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
cell part morphogenesis GO:0032990 137 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
organelle assembly GO:0070925 176 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
protein localization to organelle GO:0033365 280 0.013
cell projection organization GO:0030030 252 0.013
circulatory system development GO:0072359 262 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
negative regulation of protein processing GO:0010955 142 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
ras protein signal transduction GO:0007265 73 0.013
purine nucleoside catabolic process GO:0006152 398 0.012
nitrogen compound transport GO:0071705 191 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
response to radiation GO:0009314 151 0.012
response to extracellular stimulus GO:0009991 85 0.012
gtp metabolic process GO:0046039 239 0.012
immune response GO:0006955 307 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
regulation of actin filament based process GO:0032970 141 0.012
maintenance of location GO:0051235 112 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
apoptotic signaling pathway GO:0097190 268 0.012
endocytosis GO:0006897 159 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
actin filament based process GO:0030029 224 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
negative regulation of kinase activity GO:0033673 106 0.011
ion homeostasis GO:0050801 230 0.011
rhythmic behavior GO:0007622 2 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of cell growth GO:0001558 135 0.011
dephosphorylation GO:0016311 209 0.011
nucleoside catabolic process GO:0009164 408 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
response to nutrient levels GO:0031667 81 0.011
lipid transport GO:0006869 90 0.011
negative regulation of glial cell proliferation GO:0060253 2 0.011
regulation of cytokine production GO:0001817 232 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
cell projection morphogenesis GO:0048858 129 0.011
cellular chemical homeostasis GO:0055082 180 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
regulation of immune response GO:0050776 201 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
regulation of nervous system development GO:0051960 88 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
single organism cellular localization GO:1902580 332 0.010
oocyte differentiation GO:0009994 2 0.010
spermatid development GO:0007286 4 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
cytoplasmic transport GO:0016482 379 0.010
nuclear transport GO:0051169 179 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
neuron differentiation GO:0030182 138 0.010
cellular homeostasis GO:0019725 196 0.010
regulation of organelle assembly GO:1902115 40 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
secretion by cell GO:0032940 226 0.010
cell type specific apoptotic process GO:0097285 125 0.010
response to axon injury GO:0048678 1 0.010
regulation of map kinase activity GO:0043405 108 0.010
histone modification GO:0016570 251 0.010
compound eye development GO:0048749 1 0.010
regulation of cell differentiation GO:0045595 393 0.010

FBXW5 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 0.057
kidney disease DOID:557 36 0.037
disease of cellular proliferation DOID:14566 174 0.013
central nervous system disease DOID:331 186 0.012
neurodegenerative disease DOID:1289 102 0.012
nervous system disease DOID:863 431 0.012
disease of metabolism DOID:0014667 295 0.011
cancer DOID:162 167 0.010
organ system cancer DOID:0050686 164 0.010