|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.993
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.987
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.969
|
Yeast |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.931
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.867
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.820
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.665
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.613
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.570
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.493
|
Mouse |
|
|
replication fork processing
|
GO:0031297 |
13 |
0.487
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.464
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.454
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.391
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.361
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.348
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.334
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.322
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.315
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.220
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.218
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.210
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.208
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.205
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.198
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.192
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.183
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.179
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.179
|
Mouse |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.176
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.173
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.164
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.162
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.160
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.157
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.152
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.147
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.147
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.146
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.144
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.143
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.127
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.126
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.124
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.119
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.115
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.114
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.112
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.109
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.109
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.106
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.103
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.103
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.100
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.100
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.096
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.093
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.088
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.088
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.087
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.087
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.086
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.086
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.086
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.086
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.086
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.084
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.083
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.082
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.082
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.081
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.080
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.079
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.079
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.078
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.078
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.076
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.075
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.074
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.072
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.072
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.071
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.071
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.070
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.070
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.070
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.069
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.069
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.068
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.067
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.067
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.067
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.066
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.065
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.064
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.064
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.064
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.063
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.062
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.061
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.060
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.060
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.058
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.058
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.057
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.057
|
Yeast |
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.057
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.056
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.056
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.056
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.055
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.055
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.054
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.054
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.053
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.053
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.053
|
Yeast |
|
|
response to hormone
|
GO:0009725 |
175 |
0.052
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.052
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.052
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.051
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.051
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.051
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.050
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.050
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.050
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.049
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.049
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.049
|
Mouse |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.049
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.049
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.049
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.049
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.048
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.048
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.048
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.048
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.047
|
Yeast |
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
9 |
0.045
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.044
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.044
|
|
|
|
system process
|
GO:0003008 |
349 |
0.044
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.044
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.044
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.044
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.043
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.043
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.042
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.042
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.042
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.041
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.041
|
|
|
|
memory
|
GO:0007613 |
3 |
0.041
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.041
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.040
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.039
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.039
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.039
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.039
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.038
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.038
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.038
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.038
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.037
|
Yeast |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.036
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.035
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.034
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.034
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.034
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.034
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.033
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.033
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.033
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.033
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.033
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.033
|
Mouse |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.032
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.032
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.032
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.032
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.032
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.032
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.032
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.031
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.031
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.031
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.031
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.031
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.031
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.031
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.031
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.031
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.031
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.030
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.030
|
Mouse |
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.030
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.030
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.030
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.030
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.029
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.029
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.029
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.029
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.029
|
|
|
|
cellular hyperosmotic response
|
GO:0071474 |
4 |
0.029
|
|
|
|
protein neddylation
|
GO:0045116 |
7 |
0.028
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.028
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.028
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.028
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.028
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.028
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
9 |
0.028
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.027
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.027
|
|
|
|
growth
|
GO:0040007 |
202 |
0.027
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.027
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.027
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.026
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.026
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.026
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.026
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.026
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.026
|
Mouse |
|
|
glomerulus development
|
GO:0032835 |
15 |
0.025
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.025
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.025
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.025
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.025
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.025
|
|
|
|
histone exchange
|
GO:0043486 |
3 |
0.025
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.025
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.025
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.025
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.025
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.025
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.025
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.024
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.024
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.024
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.024
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.024
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.024
|
Yeast |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.024
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.024
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.024
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.024
|
Yeast |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.024
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.024
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.024
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.023
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.023
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.023
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.023
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.023
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.023
|
Mouse |
|
|
behavior
|
GO:0007610 |
112 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.023
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.023
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.023
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.023
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.023
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.023
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.023
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.023
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.023
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.022
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.022
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.022
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.022
|
|
|
|
response to glucagon
|
GO:0033762 |
1 |
0.022
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.022
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.022
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.022
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.022
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.021
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.021
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.021
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.021
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.021
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.021
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.021
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.021
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.021
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.021
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.021
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.021
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.021
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.021
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.021
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.021
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.021
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.021
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.020
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.020
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.020
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.020
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.020
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.020
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.020
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.020
|
|
|
|
dna dependent dna replication maintenance of fidelity
|
GO:0045005 |
14 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.019
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.019
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.019
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.019
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.019
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.019
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.019
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.018
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.018
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.018
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.018
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.018
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.018
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.018
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.018
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.018
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.018
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.018
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.018
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.018
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.018
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.018
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.018
|
|
|
|
aging
|
GO:0007568 |
66 |
0.018
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.017
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.017
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.017
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.017
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.017
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.017
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.017
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.017
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.017
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.017
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.017
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.017
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.017
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
7 |
0.017
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.017
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.017
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.017
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.017
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.017
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.017
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.017
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.017
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.017
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.016
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.016
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.016
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.016
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.016
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.016
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.016
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.016
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.016
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.016
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.016
|
Yeast |
|
|
muscle system process
|
GO:0003012 |
81 |
0.016
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.016
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.015
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.015
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.015
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.015
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.015
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.015
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.015
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.015
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.015
|
|
|
|
regulation of cellular ph
|
GO:0030641 |
17 |
0.015
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.015
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.015
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.015
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.015
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.015
|
Yeast |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.015
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.015
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.015
|
Yeast |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.015
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.015
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.015
|
|
|
|
regulation of centrosome duplication
|
GO:0010824 |
14 |
0.015
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.015
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.015
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.015
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.015
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.015
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.015
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.015
|
Yeast |
|
|
immune effector process
|
GO:0002252 |
159 |
0.015
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.014
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.014
|
|
|
|
negative regulation of tor signaling
|
GO:0032007 |
11 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
|
|
|
glomerular visceral epithelial cell differentiation
|
GO:0072112 |
4 |
0.014
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.014
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.014
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.014
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.014
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.014
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.014
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.014
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.014
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.014
|
Mouse |
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.014
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.014
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.014
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.014
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.014
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.014
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.014
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.014
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.014
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.014
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.014
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.014
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.014
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.014
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.014
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.014
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.014
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.014
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.014
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.014
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.014
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.014
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.013
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.013
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.013
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.013
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.013
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.013
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.013
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.013
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.013
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.013
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.013
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.013
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.013
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.013
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.013
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.013
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.013
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.013
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.013
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.013
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.013
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.013
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.013
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.013
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.013
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.013
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.013
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.013
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.012
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.012
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.012
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.012
|
|
|
|
striated muscle adaptation
|
GO:0014888 |
4 |
0.012
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.012
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.012
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.012
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.012
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.012
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.012
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.012
|
|
|
|
head development
|
GO:0060322 |
108 |
0.012
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.012
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.012
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.012
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.012
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.012
|
|
