Homo sapiens

81 known processes

TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

(Aliases: FAA3,AAT3,LDS2B,MFS2,TAAD2,TGFR-2,TGFbeta-RII,RIIC,LDS1B)

TGFBR2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 22 1.000
Human
positive regulation of odontogenesis GO:0042482 3 1.000
positive regulation of cardioblast differentiation GO:0051891 2 1.000
pathway restricted smad protein phosphorylation GO:0060389 38 1.000
negative regulation of macrophage cytokine production GO:0010936 3 1.000
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 1.000
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 1.000
Human
regulation of smad protein import into nucleus GO:0060390 10 1.000
Human
positive regulation of hair follicle maturation GO:0048818 2 1.000
craniofacial suture morphogenesis GO:0097094 3 1.000
positive regulation of map kinase activity GO:0043406 80 1.000
Human
embryonic cranial skeleton morphogenesis GO:0048701 6 1.000
Mouse
bone mineralization GO:0030282 34 1.000
Human
regulation of activin receptor signaling pathway GO:0032925 14 0.999
Human
cardiac epithelial to mesenchymal transition GO:0060317 3 0.999
regulation of biomineral tissue development GO:0070167 31 0.999
Human
positive regulation of biomineral tissue development GO:0070169 20 0.999
Human
salivary gland morphogenesis GO:0007435 4 0.999
endocardial cushion development GO:0003197 3 0.999
Human
regulation of bone mineralization GO:0030500 29 0.999
Human
positive regulation of protein kinase activity GO:0045860 190 0.999
Human Mouse
mesenchymal cell development GO:0014031 50 0.999
Human
activation of mapk activity GO:0000187 45 0.998
Human
smad protein import into nucleus GO:0007184 13 0.998
Human
positive regulation of aldosterone metabolic process GO:0032346 2 0.997
activation of protein kinase activity GO:0032147 90 0.996
Human Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.996
Human
positive regulation of mesonephros development GO:0061213 2 0.996
positive regulation of bone mineralization GO:0030501 19 0.996
Human
epithelium development GO:0060429 227 0.996
Human Mouse
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.995
positive regulation of transferase activity GO:0051347 227 0.995
Human Mouse
lung alveolus development GO:0048286 4 0.994
mesenchymal cell differentiation GO:0048762 52 0.994
Human
myeloid leukocyte cytokine production GO:0061082 5 0.994
positive regulation of protein phosphorylation GO:0001934 313 0.994
Human Mouse
regulation of reactive oxygen species metabolic process GO:2000377 41 0.994
regulation of collagen metabolic process GO:0010712 15 0.994
glial cell migration GO:0008347 4 0.994
patterning of blood vessels GO:0001569 2 0.993
Mouse
regulation of multicellular organismal metabolic process GO:0044246 17 0.992
positive regulation of mapk cascade GO:0043410 190 0.992
Human
positive regulation of catagen GO:0051795 2 0.991
response to prostaglandin e GO:0034695 6 0.990
regulation of macrophage cytokine production GO:0010935 4 0.990
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.989
common partner smad protein phosphorylation GO:0007182 3 0.989
Rat
enzyme linked receptor protein signaling pathway GO:0007167 303 0.989
stem cell development GO:0048864 69 0.988
Human
positive regulation of ossification GO:0045778 32 0.986
Human
positive regulation of isotype switching to iga isotypes GO:0048298 2 0.986
regulation of odontogenesis GO:0042481 4 0.986
biomineral tissue development GO:0031214 39 0.985
Human
positive regulation of dna metabolic process GO:0051054 73 0.985
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.984
protein autophosphorylation GO:0046777 123 0.983
Human
blood circulation GO:0008015 113 0.982
Human
regulation of fibroblast migration GO:0010762 7 0.981
response to steroid hormone GO:0048545 80 0.980
Rat
cytokine production involved in immune response GO:0002367 27 0.979
negative regulation of calcium ion transport into cytosol GO:0010523 3 0.978
striated muscle cell proliferation GO:0014855 7 0.978
Rat
positive regulation of phosphorylation GO:0042327 394 0.976
Human Mouse
regulation of mitosis GO:0007088 63 0.976
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.976
Human
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.975
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.975
regulation of cellular amine metabolic process GO:0033238 11 0.974
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.973
Human
regulation of map kinase activity GO:0043405 108 0.972
Human
epithelial cell proliferation GO:0050673 128 0.972
Human
embryonic neurocranium morphogenesis GO:0048702 1 0.972
endothelial cell proliferation GO:0001935 65 0.972
Human
protein targeting to nucleus GO:0044744 104 0.971
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.969
positive regulation of developmental process GO:0051094 314 0.968
Human Mouse Rat
positive regulation of hair cycle GO:0042635 3 0.967
cell type specific apoptotic process GO:0097285 125 0.967
Mouse
angiogenesis involved in wound healing GO:0060055 4 0.967
gland morphogenesis GO:0022612 8 0.967
Mouse
positive regulation of dna replication GO:0045740 35 0.965
detection of chemical stimulus GO:0009593 55 0.965
regulation of locomotion GO:0040012 329 0.962
Human Mouse
regulation of epithelial cell proliferation GO:0050678 113 0.962
Human
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.962
negative regulation of epithelial cell proliferation GO:0050680 48 0.961
blood vessel development GO:0001568 172 0.961
Human Mouse Rat
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.960
Human
positive regulation of intracellular protein transport GO:0090316 76 0.960
Human
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 11 0.957
positive regulation of stem cell differentiation GO:2000738 29 0.957
regulation of cell adhesion GO:0030155 166 0.957
Human
regulation of protein localization GO:0032880 296 0.956
Human
response to progesterone GO:0032570 5 0.956
negative regulation of cytokine production involved in immune response GO:0002719 13 0.956
tissue remodeling GO:0048771 16 0.955
cytokine production GO:0001816 247 0.954
regulation of kinase activity GO:0043549 314 0.953
Human Mouse
cell cell junction organization GO:0045216 69 0.953
Human
response to ketone GO:1901654 19 0.953
dna replication GO:0006260 116 0.952
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.952
muscle tissue development GO:0060537 62 0.952
Human Rat
negative regulation of alkaline phosphatase activity GO:0010693 2 0.952
regulation of mapk cascade GO:0043408 262 0.952
Human
regulation of stem cell differentiation GO:2000736 56 0.952
establishment of protein localization to organelle GO:0072594 172 0.951
Human
regulation of interleukin 17 production GO:0032660 12 0.949
positive regulation of kinase activity GO:0033674 204 0.949
Human Mouse
tube development GO:0035295 125 0.947
Human Mouse Rat
interleukin 17 production GO:0032620 12 0.947
single organism nuclear import GO:1902593 104 0.946
Human
regulation of cardioblast differentiation GO:0051890 4 0.946
regulation of adherens junction organization GO:1903391 21 0.945
Human
regulation of epithelial to mesenchymal transition GO:0010717 37 0.945
positive regulation of protein import into nucleus GO:0042307 46 0.944
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.943
cellular ketone metabolic process GO:0042180 80 0.943
muscle cell proliferation GO:0033002 35 0.942
Rat
blood vessel morphogenesis GO:0048514 162 0.942
Human Mouse Rat
protein import GO:0017038 130 0.940
Human
wound healing GO:0042060 115 0.940
Human Rat
morphogenesis of a branching structure GO:0001763 21 0.940
Mouse
negative regulation of trophoblast cell migration GO:1901164 3 0.939
Human
negative regulation of skeletal muscle tissue development GO:0048642 2 0.938
regulation of ossification GO:0030278 58 0.937
Human
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.936
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.935
Human
regulation of cell migration GO:0030334 289 0.934
Human Mouse
neuroblast proliferation GO:0007405 4 0.934
cell junction organization GO:0034330 79 0.933
Human
negative regulation of locomotion GO:0040013 118 0.933
Human
regulation of cytokine production GO:0001817 232 0.933
regulation of endothelial cell migration GO:0010594 67 0.932
Human
regulation of catagen GO:0051794 3 0.931
regulation of transferase activity GO:0051338 355 0.931
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.930
gland development GO:0048732 48 0.930
Mouse
mesenchyme development GO:0060485 59 0.930
Human
positive regulation of hair follicle development GO:0051798 3 0.929
regulation of blood vessel endothelial cell migration GO:0043535 30 0.929
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.929
negative regulation of dna metabolic process GO:0051053 57 0.928
Human
vascular wound healing GO:0061042 4 0.925
regulation of cellular amino acid metabolic process GO:0006521 6 0.925
polysaccharide metabolic process GO:0005976 33 0.924
positive regulation of protein kinase b signaling GO:0051897 42 0.922
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.922
Human
skeletal system development GO:0001501 79 0.920
Human Mouse
positive regulation of endothelial cell migration GO:0010595 39 0.919
Human
single organism cellular localization GO:1902580 332 0.918
Human
positive regulation of chemotaxis GO:0050921 57 0.918
positive regulation of endothelial cell proliferation GO:0001938 37 0.918
Human
response to organic cyclic compound GO:0014070 204 0.917
regulation of nucleocytoplasmic transport GO:0046822 98 0.916
Human
negative regulation of cell proliferation GO:0008285 228 0.916
Human Rat
macrophage cytokine production GO:0010934 4 0.914
ameboidal type cell migration GO:0001667 135 0.914
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 60 0.914
regulation of axon guidance GO:1902667 3 0.914
response to fatty acid GO:0070542 13 0.913
regulation of ion transport GO:0043269 189 0.913
regulation of dna replication GO:0006275 68 0.912
embryonic organ morphogenesis GO:0048562 24 0.911
Human Mouse
skeletal system morphogenesis GO:0048705 24 0.911
Mouse
regulation of protein secretion GO:0050708 86 0.908
regulation of cellular component biogenesis GO:0044087 281 0.905
Human
positive regulation of intracellular transport GO:0032388 104 0.904
Human
positive regulation of interleukin 17 production GO:0032740 8 0.903
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.900
fibroblast migration GO:0010761 7 0.900
regulation of stress activated mapk cascade GO:0032872 84 0.898
regulation of epithelial cell migration GO:0010632 93 0.896
Human Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.895
regulation of dna metabolic process GO:0051052 153 0.894
Human
cellular amine metabolic process GO:0044106 41 0.893
multicellular organismal metabolic process GO:0044236 34 0.893
negative regulation of axon guidance GO:1902668 1 0.891
regulation of cytokine production involved in immune response GO:0002718 22 0.890
response to laminar fluid shear stress GO:0034616 8 0.889
organ morphogenesis GO:0009887 147 0.889
Human Mouse Rat
response to estrogen GO:0043627 47 0.888
Rat
response to growth factor GO:0070848 205 0.887
peptidyl threonine phosphorylation GO:0018107 41 0.886
embryonic skeletal system development GO:0048706 13 0.885
Mouse
protein import into nucleus GO:0006606 104 0.884
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.883
branching involved in salivary gland morphogenesis GO:0060445 1 0.882
metal ion transport GO:0030001 272 0.880
negative regulation of immune response GO:0050777 40 0.879
lipid metabolic process GO:0006629 381 0.878
positive regulation of locomotion GO:0040017 186 0.877
Human Mouse
positive regulation of fibroblast migration GO:0010763 3 0.875
embryonic heart tube morphogenesis GO:0003143 8 0.875
Human
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.871
protein localization to organelle GO:0033365 280 0.871
Human
positive regulation of behavior GO:0048520 60 0.868
regulation of cell growth GO:0001558 135 0.864
Human
negative regulation of dna replication GO:0008156 29 0.863
cellular response to organic cyclic compound GO:0071407 127 0.863
regulation of establishment of protein localization GO:0070201 242 0.861
Human
mammary gland morphogenesis GO:0060443 2 0.861
Mouse
positive regulation of cellular component organization GO:0051130 376 0.861
epithelial cell differentiation GO:0030855 141 0.858
Human
regulation of metal ion transport GO:0010959 120 0.856
regulation of glomerulus development GO:0090192 3 0.856
positive regulation of cell migration GO:0030335 172 0.856
Human Mouse
mapk cascade GO:0000165 288 0.856
Human
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.855
hemopoiesis GO:0030097 180 0.853
Human Mouse
axis elongation GO:0003401 4 0.853
regulation of protein targeting GO:1903533 91 0.851
Human
mucopolysaccharide metabolic process GO:1903510 27 0.850
response to abiotic stimulus GO:0009628 336 0.849
Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.848
Human
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.846
cellular amino acid metabolic process GO:0006520 116 0.846
heart process GO:0003015 62 0.840
morphogenesis of a branching epithelium GO:0061138 20 0.838
Mouse
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.837
negative regulation of epithelial cell migration GO:0010633 38 0.837
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.835
retina vasculature development in camera type eye GO:0061298 3 0.834
regulation of cellular response to growth factor stimulus GO:0090287 76 0.832
histone deacetylation GO:0016575 32 0.831
cellular protein complex assembly GO:0043623 188 0.830
negative regulation of chondrocyte proliferation GO:1902731 1 0.829
Human
retinal ganglion cell axon guidance GO:0031290 2 0.828
regulation of cartilage development GO:0061035 12 0.827
cation transport GO:0006812 331 0.821
positive regulation of protein transport GO:0051222 135 0.821
Human
protein deacylation GO:0035601 39 0.820
circulatory system process GO:0003013 113 0.817
Human
regulation of protein kinase activity GO:0045859 289 0.816
Human Mouse
nucleocytoplasmic transport GO:0006913 176 0.816
Human
positive regulation of programmed cell death GO:0043068 249 0.813
Human
reactive oxygen species metabolic process GO:0072593 75 0.811
response to wounding GO:0009611 168 0.810
Human Rat
nephron epithelium development GO:0072009 23 0.809
regulation of axon extension involved in axon guidance GO:0048841 2 0.808
neuron death GO:0070997 65 0.807
positive regulation of protein localization to nucleus GO:1900182 48 0.806
Human
venous blood vessel development GO:0060841 2 0.805
negative regulation of cell migration GO:0030336 102 0.804
Human
response to hypoxia GO:0001666 96 0.804
Rat
regulation of hyaluronan biosynthetic process GO:1900125 6 0.801
embryonic organ development GO:0048568 36 0.800
Human Mouse
regulation of protein localization to nucleus GO:1900180 85 0.800
Human
cardiac muscle cell proliferation GO:0060038 6 0.799
Rat
negative regulation of cell differentiation GO:0045596 171 0.797
positive regulation of epithelial cell migration GO:0010634 55 0.795
Human Mouse
inner ear development GO:0048839 8 0.794
regulation of cell cycle process GO:0010564 266 0.792
positive regulation of transport GO:0051050 336 0.792
Human
regulation of lipid kinase activity GO:0043550 19 0.791
hematopoietic or lymphoid organ development GO:0048534 186 0.791
Human Mouse
cellular response to glucocorticoid stimulus GO:0071385 4 0.789
negative regulation of production of molecular mediator of immune response GO:0002701 13 0.789
negative regulation of developmental process GO:0051093 247 0.787
Human Rat
response to oxygen containing compound GO:1901700 369 0.786
cell chemotaxis GO:0060326 112 0.781
sodium ion transport GO:0006814 61 0.780
regulation of calcium ion transport GO:0051924 79 0.777
cell growth GO:0016049 160 0.776
Human Mouse
negative regulation of release of sequestered calcium ion into cytosol GO:0051280 1 0.775
response to lipid GO:0033993 206 0.775
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.774
stem cell differentiation GO:0048863 93 0.774
Human
motor neuron axon guidance GO:0008045 2 0.773
nephron morphogenesis GO:0072028 15 0.773
response to alcohol GO:0097305 64 0.773
heart development GO:0007507 95 0.771
Human Mouse Rat
regulation of cell differentiation GO:0045595 393 0.771
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.771
regulation of cell motility GO:2000145 299 0.770
Human Mouse
response to oxygen levels GO:0070482 100 0.770
Rat
cardiac atrium morphogenesis GO:0003209 7 0.767
Human
peptidyl threonine modification GO:0018210 45 0.765
organonitrogen compound biosynthetic process GO:1901566 200 0.764
negative regulation of axon extension GO:0030517 2 0.763
connective tissue development GO:0061448 39 0.763
Human Mouse
kidney epithelium development GO:0072073 25 0.762
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.761
atrial septum morphogenesis GO:0060413 5 0.760
Human
branching involved in ureteric bud morphogenesis GO:0001658 9 0.760
immune effector process GO:0002252 159 0.759
kidney development GO:0001822 53 0.759
myeloid cell differentiation GO:0030099 117 0.758
Human Mouse
aminoglycan metabolic process GO:0006022 39 0.758
regulation of mesonephros development GO:0061217 3 0.756
positive regulation of smad protein import into nucleus GO:0060391 8 0.756
Human
negative regulation of striated muscle tissue development GO:0045843 11 0.755
Rat
immune system development GO:0002520 195 0.755
Human Mouse
response to decreased oxygen levels GO:0036293 96 0.753
Rat
positive regulation of secretion by cell GO:1903532 108 0.753
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.753
positive regulation of cytokine production GO:0001819 167 0.751
positive regulation of apoptotic signaling pathway GO:2001235 70 0.748
Human
positive regulation of collagen biosynthetic process GO:0032967 9 0.747
positive regulation of cell cycle GO:0045787 140 0.747
ossification GO:0001503 121 0.747
Human
cerebral cortex cell migration GO:0021795 3 0.746
negative regulation of hyaluronan biosynthetic process GO:1900126 3 0.742
kidney vasculature morphogenesis GO:0061439 1 0.742
response to hormone GO:0009725 175 0.742
Rat
cellular macromolecular complex assembly GO:0034622 324 0.742
positive regulation of multicellular organismal metabolic process GO:0044253 11 0.740
response to fluid shear stress GO:0034405 14 0.740
bone morphogenesis GO:0060349 10 0.739
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.739
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.739
regulation of smooth muscle cell differentiation GO:0051150 3 0.738
endocardial cushion cell differentiation GO:0061443 1 0.731
Human
protein targeting GO:0006605 187 0.729
Human
protein secretion GO:0009306 98 0.729
secretion GO:0046903 254 0.727
epithelial to mesenchymal transition GO:0001837 48 0.726
Human
blastoderm segmentation GO:0007350 2 0.726
thymus development GO:0048538 3 0.723
regulation of vascular wound healing GO:0061043 2 0.721
palate development GO:0060021 13 0.718
Mouse
regulation of cell morphogenesis GO:0022604 153 0.717
tissue morphogenesis GO:0048729 96 0.715
Human Mouse
neuron apoptotic process GO:0051402 39 0.714
signal transduction by phosphorylation GO:0023014 297 0.714
Human
positive regulation of hormone biosynthetic process GO:0046886 4 0.713
chemotaxis GO:0006935 157 0.713
atrioventricular valve development GO:0003171 3 0.712
Human
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 0.711
negative regulation of neuron apoptotic process GO:0043524 23 0.711
cell development GO:0048468 328 0.711
Human Mouse
forebrain generation of neurons GO:0021872 3 0.709
positive regulation of epithelial cell proliferation GO:0050679 65 0.709
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.706
smooth muscle cell differentiation GO:0051145 8 0.703
sprouting angiogenesis GO:0002040 29 0.702
cranial nerve development GO:0021545 4 0.701
artery morphogenesis GO:0048844 7 0.701
regulation of hair follicle maturation GO:0048819 3 0.697
regulation of muscle tissue development GO:1901861 26 0.697
Rat
regulation of behavior GO:0050795 82 0.696
regulation of intracellular protein transport GO:0033157 123 0.694
Human
avoidance of defenses of other organism involved in symbiotic interaction GO:0051832 2 0.689
taxis GO:0042330 157 0.688
heart morphogenesis GO:0003007 48 0.686
Human
peptidyl serine modification GO:0018209 106 0.685
regulation of peptidyl serine phosphorylation GO:0033135 50 0.684
negative regulation of apoptotic process GO:0043066 316 0.680
Human
response to sterol GO:0036314 14 0.678
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.678
chordate embryonic development GO:0043009 34 0.677
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 16 0.676
Human
regulation of immune effector process GO:0002697 91 0.676
positive regulation of b cell mediated immunity GO:0002714 4 0.674
nuclear transport GO:0051169 179 0.672
Human
regulation of polysaccharide biosynthetic process GO:0032885 20 0.671
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.670
Mouse
positive regulation of vascular wound healing GO:0035470 1 0.668
divalent inorganic cation transport GO:0072511 158 0.667
regulation of mast cell chemotaxis GO:0060753 4 0.663
regulation of cell development GO:0060284 161 0.662
endocrine system development GO:0035270 26 0.661
circulatory system development GO:0072359 262 0.659
Human Mouse Rat
positive regulation of growth GO:0045927 58 0.659
Human Rat
positive regulation of immune system process GO:0002684 283 0.657
Human Mouse
developmental growth involved in morphogenesis GO:0060560 23 0.657
Mouse
amine metabolic process GO:0009308 44 0.657
bone development GO:0060348 26 0.655
Mouse
female pregnancy GO:0007565 17 0.652
Human Rat
molting cycle process GO:0022404 12 0.652
regulation of cellular component movement GO:0051270 334 0.649
Human Mouse
ossification involved in bone remodeling GO:0043932 2 0.649
nuclear import GO:0051170 106 0.646
Human
negative regulation of cytokine production GO:0001818 82 0.643
calcium ion transport GO:0006816 147 0.643
regulation of neuron apoptotic process GO:0043523 35 0.640
regulation of cytoplasmic transport GO:1903649 149 0.639
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.638
Human
neural crest cell migration GO:0001755 2 0.637
cell migration involved in sprouting angiogenesis GO:0002042 19 0.637
positive regulation of cell development GO:0010720 92 0.635
negative regulation of catalytic activity GO:0043086 335 0.629
peptidyl tyrosine phosphorylation GO:0018108 170 0.626
cardiocyte differentiation GO:0035051 23 0.624
Human
regulation of neuron death GO:1901214 56 0.622
cardiac muscle cell fate commitment GO:0060923 4 0.619
Human
mesonephric tubule morphogenesis GO:0072171 10 0.615
post embryonic development GO:0009791 2 0.614
regulation of secretion GO:0051046 194 0.614
cellular calcium ion homeostasis GO:0006874 117 0.614
cell migration involved in kidney development GO:0035787 2 0.613
positive regulation of histone deacetylase activity GO:1901727 3 0.611
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.610
ureteric bud morphogenesis GO:0060675 10 0.610
negative regulation of coagulation GO:0050819 24 0.606
cellular lipid metabolic process GO:0044255 303 0.601
regulation of muscle organ development GO:0048634 27 0.594
Rat
cellular response to endogenous stimulus GO:0071495 336 0.594
muscle cell migration GO:0014812 19 0.594
cell projection organization GO:0030030 252 0.590
positive regulation of secretion GO:0051047 116 0.589
actin filament based process GO:0030029 224 0.589
aminoglycan catabolic process GO:0006026 10 0.588
cellular response to corticosteroid stimulus GO:0071384 5 0.586
mitotic cell cycle process GO:1903047 286 0.586
Human
production of molecular mediator of immune response GO:0002440 37 0.585
positive regulation of hydrolase activity GO:0051345 331 0.584
Human
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.583
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.580
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.578
epithelium migration GO:0090132 119 0.577
Human Mouse
myeloid dendritic cell differentiation GO:0043011 3 0.576
Mouse
regulation of alkaline phosphatase activity GO:0010692 2 0.575
angiogenesis GO:0001525 147 0.575
Human Mouse
hair cycle GO:0042633 28 0.572
regulation of immune response GO:0050776 201 0.572
positive regulation of response to external stimulus GO:0032103 88 0.570
regulation of production of molecular mediator of immune response GO:0002700 25 0.569
regulation of protein import into nucleus GO:0042306 78 0.566
Human
positive regulation of mast cell chemotaxis GO:0060754 4 0.565
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.563
response to electrical stimulus GO:0051602 1 0.562
establishment of endothelial barrier GO:0061028 16 0.561
positive regulation of lipid metabolic process GO:0045834 50 0.556
regulation of binding GO:0051098 111 0.556
endothelial cell migration GO:0043542 86 0.552
Human
defense response to fungus GO:0050832 4 0.548
system process GO:0003008 349 0.548
Human
negative regulation of multicellular organismal process GO:0051241 317 0.547
Human Rat
morphogenesis of an epithelium GO:0002009 60 0.547
Human Mouse
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.546
regulation of filopodium assembly GO:0051489 13 0.546
specification of symmetry GO:0009799 16 0.546
Human
forebrain neuron development GO:0021884 2 0.545
regulation of smooth muscle cell migration GO:0014910 15 0.544
action potential GO:0001508 34 0.542
carbohydrate biosynthetic process GO:0016051 42 0.540
embryo development GO:0009790 123 0.540
Human Mouse Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.539
cytoplasmic transport GO:0016482 379 0.539
Human
transmission of nerve impulse GO:0019226 11 0.538
respiratory system development GO:0060541 22 0.537
Mouse Rat
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.537
negative regulation of neuron death GO:1901215 32 0.535
regulation of endothelial cell proliferation GO:0001936 56 0.530
Human
negative regulation of immune effector process GO:0002698 38 0.529
aminoglycan biosynthetic process GO:0006023 29 0.527
myeloid dendritic cell activation GO:0001773 4 0.515
Mouse
defense response GO:0006952 315 0.512
regulation of intracellular transport GO:0032386 195 0.512
Human
negative regulation of cellular component movement GO:0051271 106 0.511
Human
mitral valve morphogenesis GO:0003183 2 0.509
Human
negative regulation of cell activation GO:0050866 33 0.509
biological adhesion GO:0022610 331 0.505
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.505
nuclear division GO:0000280 128 0.503
cell migration involved in metanephros development GO:0035788 2 0.503
epithelial tube morphogenesis GO:0060562 38 0.503
Human Mouse
positive regulation of collagen metabolic process GO:0010714 9 0.501
positive regulation of cell proliferation GO:0008284 301 0.501
Human Mouse Rat
regulation of cell junction assembly GO:1901888 29 0.501
Human
negative regulation of phagocytosis GO:0050765 4 0.501
inositol lipid mediated signaling GO:0048017 55 0.501
cardiac chamber morphogenesis GO:0003206 26 0.500
Human
mesonephros development GO:0001823 17 0.499
kidney morphogenesis GO:0060993 19 0.497
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.497
negative regulation of cell death GO:0060548 345 0.494
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.491
dna biosynthetic process GO:0071897 40 0.489
Human
phospholipid metabolic process GO:0006644 99 0.488
positive regulation of metanephric mesenchymal cell migration GO:2000591 2 0.488
regulation of hormone levels GO:0010817 125 0.488
atrial septum primum morphogenesis GO:0003289 1 0.485
Human
lens development in camera type eye GO:0002088 2 0.484
Mouse
epithelial cell fate commitment GO:0072148 3 0.483
Human
negative regulation of hydrolase activity GO:0051346 182 0.482
regulation of cell proliferation involved in kidney development GO:1901722 3 0.482
protein deacetylation GO:0006476 38 0.480
positive regulation of protein secretion GO:0050714 60 0.475
ribonucleotide biosynthetic process GO:0009260 81 0.474
venous blood vessel morphogenesis GO:0048845 1 0.473
cellular response to growth factor stimulus GO:0071363 197 0.471
lung development GO:0030324 20 0.471
Mouse Rat
smad protein complex assembly GO:0007183 12 0.468

TGFBR2 disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.961
musculoskeletal system disease DOID:17 223 0.961
Human
cardiovascular system disease DOID:1287 106 0.940
Human
myopathy DOID:423 104 0.902
heart disease DOID:114 68 0.902
Human
cardiomyopathy DOID:0050700 50 0.902
muscle tissue disease DOID:66 113 0.902
intrinsic cardiomyopathy DOID:0060036 50 0.574
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 9 0.574