Homo sapiens

0 known processes

TJP3

tight junction protein 3 (zona occludens 3)

(Aliases: MGC119546,ZO3,ZO-3)

TJP3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
water homeostasis GO:0030104 14 0.297
actin filament based process GO:0030029 224 0.169
Worm
actin cytoskeleton organization GO:0030036 207 0.150
Worm
nucleotide catabolic process GO:0009166 408 0.150
membrane organization GO:0061024 292 0.148
peripheral nervous system development GO:0007422 2 0.120
cell junction organization GO:0034330 79 0.116
tube development GO:0035295 125 0.115
ras protein signal transduction GO:0007265 73 0.095
ribonucleotide catabolic process GO:0009261 405 0.095
regulation of purine nucleotide metabolic process GO:1900542 264 0.094
endomembrane system organization GO:0010256 196 0.087
protein localization to adherens junction GO:0071896 2 0.085
negative regulation of phosphate metabolic process GO:0045936 267 0.084
rho protein signal transduction GO:0007266 26 0.081
regulation of response to external stimulus GO:0032101 222 0.081
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 2 0.079
regulation of epithelial cell proliferation GO:0050678 113 0.079
negative regulation of catalytic activity GO:0043086 335 0.078
morphogenesis of embryonic epithelium GO:0016331 4 0.077
embryonic epithelial tube formation GO:0001838 4 0.074
single organism membrane organization GO:0044802 268 0.073
purine containing compound catabolic process GO:0072523 411 0.073
biological adhesion GO:0022610 331 0.073
purine ribonucleoside metabolic process GO:0046128 437 0.069
apoptotic signaling pathway GO:0097190 268 0.065
neural tube formation GO:0001841 3 0.064
plasma membrane organization GO:0007009 115 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.063
purine ribonucleoside catabolic process GO:0046130 398 0.062
cellular amino acid metabolic process GO:0006520 116 0.061
nucleoside phosphate catabolic process GO:1901292 412 0.061
ameboidal type cell migration GO:0001667 135 0.060
guanosine containing compound catabolic process GO:1901069 239 0.060
regulation of protein complex assembly GO:0043254 147 0.060
metal ion homeostasis GO:0055065 169 0.059
nucleoside triphosphate metabolic process GO:0009141 422 0.058
purine nucleoside triphosphate catabolic process GO:0009146 392 0.056
system process GO:0003008 349 0.054
amine metabolic process GO:0009308 44 0.054
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.052
organ morphogenesis GO:0009887 147 0.051
nucleoside triphosphate catabolic process GO:0009143 394 0.051
gtp metabolic process GO:0046039 239 0.048
response to wounding GO:0009611 168 0.048
regulation of cytoskeleton organization GO:0051493 177 0.048
cellular amine metabolic process GO:0044106 41 0.048
regulation of cellular amino acid metabolic process GO:0006521 6 0.048
multicellular organismal water homeostasis GO:0050891 14 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
ribonucleoside catabolic process GO:0042454 406 0.047
cell morphogenesis GO:0000902 296 0.047
single organism cell adhesion GO:0098602 179 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
glycosyl compound catabolic process GO:1901658 413 0.046
nucleoside catabolic process GO:0009164 408 0.045
regulation of response to wounding GO:1903034 101 0.044
regulation of small gtpase mediated signal transduction GO:0051056 156 0.044
positive regulation of protein complex assembly GO:0031334 86 0.044
ribonucleoside triphosphate metabolic process GO:0009199 412 0.043
cellular ketone metabolic process GO:0042180 80 0.042
cell projection assembly GO:0030031 126 0.042
positive regulation of ras gtpase activity GO:0032320 117 0.041
regulation of purine nucleotide catabolic process GO:0033121 205 0.041
positive regulation of transport GO:0051050 336 0.040
guanosine containing compound metabolic process GO:1901068 244 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
cellular macromolecular complex assembly GO:0034622 324 0.039
regulation of actin filament based process GO:0032970 141 0.039
organophosphate catabolic process GO:0046434 430 0.038
chemical homeostasis GO:0048878 306 0.038
regulation of nucleoside metabolic process GO:0009118 209 0.038
cell chemotaxis GO:0060326 112 0.038
response to abiotic stimulus GO:0009628 336 0.038
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.037
positive regulation of nucleotide catabolic process GO:0030813 185 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
small gtpase mediated signal transduction GO:0007264 78 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.035
taxis GO:0042330 157 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
regulation of protein kinase activity GO:0045859 289 0.033
chemotaxis GO:0006935 157 0.033
regulation of intracellular transport GO:0032386 195 0.033
regulation of actin cytoskeleton organization GO:0032956 116 0.032
positive regulation of cellular component organization GO:0051130 376 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
response to growth factor GO:0070848 205 0.031
protein maturation GO:0051604 233 0.031
memory GO:0007613 3 0.031
regulation of gtp catabolic process GO:0033124 180 0.031
blastoderm segmentation GO:0007350 2 0.030
response to oxygen containing compound GO:1901700 369 0.030
divalent metal ion transport GO:0070838 152 0.030
oogenesis GO:0048477 2 0.030
regulation of actin filament length GO:0030832 56 0.030
neurological system process GO:0050877 163 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
positive regulation of organelle organization GO:0010638 195 0.030
organelle assembly GO:0070925 176 0.030
schwann cell differentiation GO:0014037 1 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
cell matrix adhesion GO:0007160 85 0.029
nervous system development GO:0007399 293 0.029
regulation of cell migration GO:0030334 289 0.028
regulation of cell motility GO:2000145 299 0.028
cation transport GO:0006812 331 0.028
negative regulation of transport GO:0051051 176 0.027
coagulation GO:0050817 78 0.027
blood coagulation GO:0007596 76 0.027
negative regulation of protein modification process GO:0031400 200 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
regulation of body fluid levels GO:0050878 99 0.026
regulation of ras protein signal transduction GO:0046578 155 0.026
cellular lipid metabolic process GO:0044255 303 0.026
actin polymerization or depolymerization GO:0008154 56 0.026
regulation of cellular component size GO:0032535 82 0.026
exocytosis GO:0006887 71 0.026
immune response GO:0006955 307 0.026
multicellular organismal aging GO:0010259 3 0.026
generation of neurons GO:0048699 152 0.026
negative regulation of phosphorylation GO:0042326 174 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
determination of adult lifespan GO:0008340 2 0.025
lipid metabolic process GO:0006629 381 0.025
single organism cellular localization GO:1902580 332 0.025
positive regulation of cell death GO:0010942 263 0.025
regulation of blood coagulation GO:0030193 42 0.025
negative regulation of response to external stimulus GO:0032102 83 0.025
cell adhesion GO:0007155 325 0.025
female gamete generation GO:0007292 2 0.024
regulation of ras gtpase activity GO:0032318 128 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
spermatid development GO:0007286 4 0.024
calcium ion transport GO:0006816 147 0.024
cation transmembrane transport GO:0098655 238 0.023
cilium morphogenesis GO:0060271 75 0.023
regulation of proteolysis GO:0030162 293 0.023
regulation of coagulation GO:0050818 44 0.023
metal ion transport GO:0030001 272 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.023
epithelial cell differentiation GO:0030855 141 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
microtubule based process GO:0007017 210 0.023
cell projection organization GO:0030030 252 0.023
digestive tract development GO:0048565 75 0.023
protein processing GO:0016485 226 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.023
cation homeostasis GO:0055080 189 0.022
regulation of hemostasis GO:1900046 42 0.022
negative regulation of response to wounding GO:1903035 47 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
neurogenesis GO:0022008 169 0.022
regulation of transferase activity GO:0051338 355 0.021
protein localization to organelle GO:0033365 280 0.021
positive regulation of ion transport GO:0043270 87 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
schwann cell development GO:0014044 1 0.021
oocyte development GO:0048599 1 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
regulation of rho protein signal transduction GO:0035023 79 0.021
sensory organ morphogenesis GO:0090596 21 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
defense response GO:0006952 315 0.020
cellular cation homeostasis GO:0030003 163 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
cellular protein complex assembly GO:0043623 188 0.020
vesicle mediated transport GO:0016192 371 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
cellular component disassembly GO:0022411 92 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
regulation of peptidase activity GO:0052547 180 0.020
regulation of actin filament polymerization GO:0030833 50 0.019
neuromuscular junction development GO:0007528 3 0.019
cellular chemical homeostasis GO:0055082 180 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
segmentation GO:0035282 4 0.019
transmembrane transport GO:0055085 399 0.019
post embryonic development GO:0009791 2 0.019
negative regulation of organelle organization GO:0010639 126 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
protein targeting GO:0006605 187 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.019
negative regulation of cell death GO:0060548 345 0.019
Human
oocyte differentiation GO:0009994 2 0.018
positive regulation of gtpase activity GO:0043547 166 0.018
regulation of kinase activity GO:0043549 314 0.018
cellular component morphogenesis GO:0032989 314 0.018
spermatid differentiation GO:0048515 4 0.018
response to hormone GO:0009725 175 0.018
positive regulation of developmental process GO:0051094 314 0.018
peripheral nervous system axon ensheathment GO:0032292 1 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
ion transmembrane transport GO:0034220 338 0.017
skin development GO:0043588 76 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
ion homeostasis GO:0050801 230 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
positive regulation of catabolic process GO:0009896 310 0.017
cell fate determination GO:0001709 3 0.017
intracellular protein transport GO:0006886 270 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
secretion by cell GO:0032940 226 0.017
eye photoreceptor cell differentiation GO:0001754 2 0.017
gtp catabolic process GO:0006184 237 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
protein localization to cell junction GO:1902414 3 0.016
dephosphorylation GO:0016311 209 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
positive regulation of rho gtpase activity GO:0032321 56 0.016
regulation of gtpase activity GO:0043087 180 0.016
positive regulation of proteolysis GO:0045862 142 0.016
defense response to bacterium GO:0042742 63 0.016
interspecies interaction between organisms GO:0044419 156 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
regulation of cellular response to stress GO:0080135 244 0.016
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.016
endocytosis GO:0006897 159 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
anterior posterior axis specification GO:0009948 2 0.016
small molecule biosynthetic process GO:0044283 157 0.015
response to biotic stimulus GO:0009607 276 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
cyclic purine nucleotide metabolic process GO:0052652 60 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
sequestering of metal ion GO:0051238 24 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
blastocyst development GO:0001824 3 0.015
viral process GO:0016032 146 0.015
stem cell division GO:0017145 2 0.015
transmission of nerve impulse GO:0019226 11 0.015
innate immune response GO:0045087 178 0.015
cilium assembly GO:0042384 63 0.015
regulation of ion transport GO:0043269 189 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
positive regulation of secretion GO:0051047 116 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
chromatin organization GO:0006325 351 0.014
epithelium development GO:0060429 227 0.014
regulation of behavior GO:0050795 82 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
chromatin modification GO:0016568 298 0.014
regulation of rho gtpase activity GO:0032319 66 0.014
defense response to other organism GO:0098542 129 0.014
regulation of cell activation GO:0050865 125 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
negative regulation of transferase activity GO:0051348 124 0.014
protein polymerization GO:0051258 71 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
Human
myeloid cell differentiation GO:0030099 117 0.014
negative regulation of cytoskeleton organization GO:0051494 45 0.014
cilium organization GO:0044782 68 0.014
actin filament polymerization GO:0030041 45 0.014
mitotic cell cycle process GO:1903047 286 0.014
Mouse
inorganic cation transmembrane transport GO:0098662 194 0.014
peptidyl tyrosine modification GO:0018212 170 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
oxidation reduction process GO:0055114 396 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
macromolecular complex disassembly GO:0032984 60 0.013
positive regulation of protein transport GO:0051222 135 0.013
sensory perception of pain GO:0019233 4 0.013
negative regulation of cell substrate adhesion GO:0010812 24 0.013
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.013
sequestering of calcium ion GO:0051208 17 0.013
maintenance of location GO:0051235 112 0.013
leukocyte chemotaxis GO:0030595 76 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
digestive system development GO:0055123 75 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
negative regulation of developmental process GO:0051093 247 0.013
response to cytokine GO:0034097 232 0.013
Human
anion transport GO:0006820 161 0.013
mapk cascade GO:0000165 288 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
tripartite regional subdivision GO:0007351 2 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of transmembrane transport GO:0034762 139 0.013
secretion GO:0046903 254 0.013
cell part morphogenesis GO:0032990 137 0.012
monovalent inorganic cation homeostasis GO:0055067 37 0.012
drinking behavior GO:0042756 1 0.012
calcium ion homeostasis GO:0055074 122 0.012
alcohol metabolic process GO:0006066 114 0.012
regulation of cell growth GO:0001558 135 0.012
regulation of secretion GO:0051046 194 0.012
regulation of defense response GO:0031347 154 0.012
neuron differentiation GO:0030182 138 0.012
cell growth GO:0016049 160 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
Human
compound eye development GO:0048749 1 0.012
fatty acid metabolic process GO:0006631 115 0.012
negative regulation of protein processing GO:0010955 142 0.012
actin filament based movement GO:0030048 17 0.012
cellular protein catabolic process GO:0044257 261 0.012
multicellular organismal signaling GO:0035637 34 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
cell projection morphogenesis GO:0048858 129 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.012
cytoplasmic transport GO:0016482 379 0.012
cellular homeostasis GO:0019725 196 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.011
rna processing GO:0006396 255 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
negative regulation of mapk cascade GO:0043409 56 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of cellular response to growth factor stimulus GO:0090287 76 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
regulation of anion channel activity GO:0010359 2 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
Human
microtubule cytoskeleton organization GO:0000226 176 0.011
blood circulation GO:0008015 113 0.011
muscle tissue development GO:0060537 62 0.011
protein catabolic process GO:0030163 325 0.011
positive regulation of endocytosis GO:0045807 42 0.011
embryonic placenta development GO:0001892 1 0.011
brain development GO:0007420 97 0.011
lipid biosynthetic process GO:0008610 177 0.011
negative regulation of kinase activity GO:0033673 106 0.011
gastrulation with mouth forming second GO:0001702 1 0.011
myeloid leukocyte migration GO:0097529 62 0.011
lipid modification GO:0030258 84 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
mating GO:0007618 1 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of locomotion GO:0040012 329 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
mitochondrion organization GO:0007005 156 0.011
protein ubiquitination GO:0016567 314 0.011
regulation of chemotaxis GO:0050920 74 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
response to tumor necrosis factor GO:0034612 76 0.011
Human
regulation of calcium ion transport GO:0051924 79 0.011
endosomal transport GO:0016197 129 0.011
leukocyte activation GO:0045321 164 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
positive regulation of immune system process GO:0002684 283 0.010
multi organism cellular process GO:0044764 156 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
regulation of eosinophil activation GO:1902566 2 0.010
neural crest cell development GO:0014032 3 0.010
actin filament organization GO:0007015 128 0.010
Worm
detection of stimulus GO:0051606 85 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
response to lipid GO:0033993 206 0.010
leukocyte mediated immunity GO:0002443 59 0.010
covalent chromatin modification GO:0016569 254 0.010
histone modification GO:0016570 251 0.010
protein oligomerization GO:0051259 173 0.010
synaptic vesicle recycling GO:0036465 3 0.010
engulfment of apoptotic cell GO:0043652 2 0.010
regulation of phagocytosis engulfment GO:0060099 2 0.010
growth GO:0040007 202 0.010
regulation of neuroblast proliferation GO:1902692 3 0.010
establishment of skin barrier GO:0061436 5 0.010
cardiac muscle contraction GO:0060048 34 0.010
viral life cycle GO:0019058 132 0.010
response to decreased oxygen levels GO:0036293 96 0.010
apical junction assembly GO:0043297 19 0.010

TJP3 disease predictions

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 14 0.051
lower respiratory tract disease DOID:0050161 13 0.051
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
eye and adnexa disease DOID:1492 150 0.018
retinal disease DOID:5679 118 0.015
retinal degeneration DOID:8466 89 0.015
eye disease DOID:5614 149 0.015
organ system cancer DOID:0050686 164 0.015
disease of metabolism DOID:0014667 295 0.014
inherited metabolic disorder DOID:655 242 0.012
auditory system disease DOID:2742 53 0.012
immune system disease DOID:2914 155 0.011
retinitis pigmentosa DOID:10584 51 0.011