Homo sapiens

16 known processes

RNF38

ring finger protein 38

(Aliases: FLJ21343)

RNF38 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.973
protein polyubiquitination GO:0000209 110 0.941
Human
protein ubiquitination GO:0016567 314 0.856
protein k48 linked ubiquitination GO:0070936 38 0.706
protein autoubiquitination GO:0051865 37 0.571
modification dependent macromolecule catabolic process GO:0043632 212 0.502
modification dependent protein catabolic process GO:0019941 209 0.365
cellular macromolecule catabolic process GO:0044265 380 0.361
ubiquitin dependent protein catabolic process GO:0006511 206 0.308
cellular protein catabolic process GO:0044257 261 0.283
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.258
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.242
protein monoubiquitination GO:0006513 39 0.153
hindbrain development GO:0030902 3 0.139
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.138
regulation of cell cycle GO:0051726 393 0.134
protein catabolic process GO:0030163 325 0.134
covalent chromatin modification GO:0016569 254 0.128
neurological system process GO:0050877 163 0.127
cellular macromolecular complex assembly GO:0034622 324 0.124
memory GO:0007613 3 0.114
neural tube formation GO:0001841 3 0.113
embryonic epithelial tube formation GO:0001838 4 0.096
proteasomal protein catabolic process GO:0010498 176 0.092
chromatin modification GO:0016568 298 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.081
microtubule organizing center organization GO:0031023 62 0.079
primary neural tube formation GO:0014020 3 0.076
cellular protein complex assembly GO:0043623 188 0.075
chromatin organization GO:0006325 351 0.074
cardiovascular system development GO:0072358 262 0.073
anatomical structure formation involved in morphogenesis GO:0048646 284 0.072
morphogenesis of embryonic epithelium GO:0016331 4 0.071
post embryonic development GO:0009791 2 0.071
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.071
organelle assembly GO:0070925 176 0.070
system process GO:0003008 349 0.069
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.069
embryonic camera type eye development GO:0031076 2 0.066
nervous system development GO:0007399 293 0.066
enzyme linked receptor protein signaling pathway GO:0007167 303 0.062
determination of adult lifespan GO:0008340 2 0.061
positive regulation of protein ubiquitination GO:0031398 53 0.054
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.054
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.049
response to radiation GO:0009314 151 0.048
multicellular organismal aging GO:0010259 3 0.048
wnt signaling pathway GO:0016055 156 0.048
posttranscriptional regulation of gene expression GO:0010608 213 0.047
regulation of protein ubiquitination GO:0031396 95 0.047
histone ubiquitination GO:0016574 31 0.046
cell development GO:0048468 328 0.046
protein processing GO:0016485 226 0.046
behavioral response to ethanol GO:0048149 2 0.046
response to ionizing radiation GO:0010212 65 0.045
histone modification GO:0016570 251 0.044
tube development GO:0035295 125 0.043
long term memory GO:0007616 2 0.043
actin filament based process GO:0030029 224 0.041
negative regulation of multicellular organismal process GO:0051241 317 0.041
microtubule based process GO:0007017 210 0.041
regulation of proteolysis GO:0030162 293 0.040
neuromuscular junction development GO:0007528 3 0.040
embryonic camera type eye morphogenesis GO:0048596 2 0.039
oogenesis GO:0048477 2 0.038
cellular response to endogenous stimulus GO:0071495 336 0.037
actin cytoskeleton organization GO:0030036 207 0.037
circulatory system development GO:0072359 262 0.036
metencephalon development GO:0022037 2 0.036
cell cell signaling GO:0007267 155 0.035
tube closure GO:0060606 3 0.034
protein k11 linked ubiquitination GO:0070979 24 0.034
regulation of cellular component size GO:0032535 82 0.034
embryonic morphogenesis GO:0048598 85 0.034
interspecies interaction between organisms GO:0044419 156 0.034
vasculature development GO:0001944 181 0.034
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
trophectodermal cell differentiation GO:0001829 3 0.033
female gamete generation GO:0007292 2 0.033
positive regulation of catabolic process GO:0009896 310 0.033
response to abiotic stimulus GO:0009628 336 0.031
meiotic chromosome segregation GO:0045132 4 0.031
neuron differentiation GO:0030182 138 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
somitogenesis GO:0001756 2 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
vesicle mediated transport GO:0016192 371 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
regulation of cellular component biogenesis GO:0044087 281 0.030
protein maturation GO:0051604 233 0.030
rho protein signal transduction GO:0007266 26 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.029
embryonic eye morphogenesis GO:0048048 2 0.029
segmentation GO:0035282 4 0.028
regulation of response to external stimulus GO:0032101 222 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.028
regulation of cell cycle process GO:0010564 266 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
protein polymerization GO:0051258 71 0.028
blood vessel development GO:0001568 172 0.028
negative regulation of catalytic activity GO:0043086 335 0.027
carbohydrate metabolic process GO:0005975 207 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
retrograde transport endosome to golgi GO:0042147 45 0.027
protein k63 linked ubiquitination GO:0070534 31 0.026
regulation of cellular response to stress GO:0080135 244 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
positive regulation of proteolysis GO:0045862 142 0.025
dna repair GO:0006281 198 0.025
anterior posterior axis specification GO:0009948 2 0.025
autophagy GO:0006914 88 0.025
regulation of meiosis GO:0040020 3 0.025
cellular component morphogenesis GO:0032989 314 0.025
organ morphogenesis GO:0009887 147 0.025
actin filament organization GO:0007015 128 0.025
positive regulation of cell death GO:0010942 263 0.024
generation of neurons GO:0048699 152 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
regulation of multi organism process GO:0043900 157 0.024
extrinsic apoptotic signaling pathway GO:0097191 119 0.023
male meiosis GO:0007140 1 0.023
negative regulation of cell death GO:0060548 345 0.023
regulation of protein complex assembly GO:0043254 147 0.023
regulation of protein kinase activity GO:0045859 289 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
nuclear division GO:0000280 128 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
regulation of actin polymerization or depolymerization GO:0008064 56 0.022
regulation of protein polymerization GO:0032271 63 0.022
multi organism cellular process GO:0044764 156 0.022
small molecule biosynthetic process GO:0044283 157 0.022
mapk cascade GO:0000165 288 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
organelle fission GO:0048285 149 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
regulation of mapk cascade GO:0043408 262 0.022
ras protein signal transduction GO:0007265 73 0.022
internal protein amino acid acetylation GO:0006475 101 0.022
regulation of kinase activity GO:0043549 314 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
cation transport GO:0006812 331 0.021
regulation of growth GO:0040008 165 0.021
dephosphorylation GO:0016311 209 0.021
apoptotic signaling pathway GO:0097190 268 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.021
skeletal system development GO:0001501 79 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
cellular response to abiotic stimulus GO:0071214 117 0.020
regulation of protein stability GO:0031647 87 0.020
regulation of transferase activity GO:0051338 355 0.020
regulation of protein catabolic process GO:0042176 155 0.020
macromolecule methylation GO:0043414 97 0.020
neurogenesis GO:0022008 169 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
cellular amine metabolic process GO:0044106 41 0.020
regulation of anatomical structure size GO:0090066 101 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of secretion by cell GO:1903530 177 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
positive regulation of organelle organization GO:0010638 195 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
regulation of intracellular transport GO:0032386 195 0.019
organophosphate catabolic process GO:0046434 430 0.019
androgen receptor signaling pathway GO:0030521 34 0.019
Human
spermatid differentiation GO:0048515 4 0.019
regulation of cell development GO:0060284 161 0.019
regulation of viral process GO:0050792 103 0.019
actin filament based movement GO:0030048 17 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
positive regulation of protein polymerization GO:0032273 45 0.018
regulation of actin filament based process GO:0032970 141 0.018
blastoderm segmentation GO:0007350 2 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
glycosylation GO:0070085 71 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
mrna metabolic process GO:0016071 175 0.018
demethylation GO:0070988 37 0.017
forelimb morphogenesis GO:0035136 4 0.017
locomotory behavior GO:0007626 1 0.017
cellular chemical homeostasis GO:0055082 180 0.017
cell projection organization GO:0030030 252 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
regulation of response to dna damage stimulus GO:2001020 94 0.017
protein acetylation GO:0006473 116 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
lymphocyte activation GO:0046649 133 0.016
purine containing compound catabolic process GO:0072523 411 0.016
endomembrane system organization GO:0010256 196 0.016
endocytosis GO:0006897 159 0.016
tube morphogenesis GO:0035239 95 0.016
hexose metabolic process GO:0019318 55 0.016
neurotransmitter secretion GO:0007269 4 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of cell projection organization GO:0031344 107 0.016
nucleotide catabolic process GO:0009166 408 0.016
head development GO:0060322 108 0.016
regulation of secretion GO:0051046 194 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
hemopoiesis GO:0030097 180 0.016
response to other organism GO:0051707 261 0.016
neural tube closure GO:0001843 3 0.016
monosaccharide metabolic process GO:0005996 74 0.015
mitotic cell cycle process GO:1903047 286 0.015
defense response GO:0006952 315 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
secretion GO:0046903 254 0.015
amine metabolic process GO:0009308 44 0.015
regulation of cellular response to growth factor stimulus GO:0090287 76 0.015
regulation of cell division GO:0051302 116 0.015
response to oxygen containing compound GO:1901700 369 0.015
centrosome organization GO:0051297 58 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of protein transport GO:0051223 213 0.015
response to transforming growth factor beta GO:0071559 94 0.015
protein demethylation GO:0006482 17 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
immune effector process GO:0002252 159 0.015
growth GO:0040007 202 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.015
histone lysine methylation GO:0034968 50 0.015
negative regulation of cell proliferation GO:0008285 228 0.014
negative regulation of protein maturation GO:1903318 142 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
negative regulation of growth GO:0045926 97 0.014
response to external biotic stimulus GO:0043207 261 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
nerve development GO:0021675 4 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
histone h4 acetylation GO:0043967 47 0.014
cellular response to external stimulus GO:0071496 111 0.014
macromolecule glycosylation GO:0043413 63 0.014
regulation of locomotion GO:0040012 329 0.014
protein acylation GO:0043543 138 0.014
regulation of protein processing GO:0070613 150 0.014
single organism reproductive process GO:0044702 98 0.014
epithelium development GO:0060429 227 0.014
regulation of erbb signaling pathway GO:1901184 27 0.014
regulation of nervous system development GO:0051960 88 0.014
adaptive immune response GO:0002250 49 0.013
viral gene expression GO:0019080 35 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
glucose metabolic process GO:0006006 45 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
protein glycosylation GO:0006486 62 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
reproductive process GO:0022414 106 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
single organism cellular localization GO:1902580 332 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
regulation of autophagy GO:0010506 52 0.013
cellular response to starvation GO:0009267 58 0.013
negative regulation of catabolic process GO:0009895 104 0.013
cell morphogenesis GO:0000902 296 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
canonical wnt signaling pathway GO:0060070 116 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
actin polymerization or depolymerization GO:0008154 56 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
positive regulation of transferase activity GO:0051347 227 0.013
glycoprotein metabolic process GO:0009100 110 0.013
erbb signaling pathway GO:0038127 44 0.013
positive regulation of transport GO:0051050 336 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
central nervous system development GO:0007417 123 0.013
response to extracellular stimulus GO:0009991 85 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
blood vessel morphogenesis GO:0048514 162 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
negative regulation of cell cycle GO:0045786 193 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
rhythmic behavior GO:0007622 2 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
mitotic cell cycle GO:0000278 326 0.013
cell division GO:0051301 168 0.013
embryonic organ morphogenesis GO:0048562 24 0.013
dna damage checkpoint GO:0000077 68 0.013
protein dealkylation GO:0008214 17 0.012
cellular response to nutrient levels GO:0031669 69 0.012
single organism membrane organization GO:0044802 268 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
establishment of nucleus localization GO:0040023 1 0.012
cellular response to radiation GO:0071478 65 0.012
rna processing GO:0006396 255 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
metal ion transport GO:0030001 272 0.012
cell growth GO:0016049 160 0.012
transmembrane transport GO:0055085 399 0.012
regulation of protein localization GO:0032880 296 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.012
positive regulation of immune system process GO:0002684 283 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
cognition GO:0050890 43 0.012
secretion by cell GO:0032940 226 0.012
membrane organization GO:0061024 292 0.012
protein deubiquitination GO:0016579 79 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
response to growth factor GO:0070848 205 0.012
limbic system development GO:0021761 3 0.012
embryonic placenta development GO:0001892 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
Human
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
response to bacterium GO:0009617 144 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of carbohydrate metabolic process GO:0006109 54 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
neuron development GO:0048666 113 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
regulation of viral transcription GO:0046782 34 0.011
cell cycle checkpoint GO:0000075 117 0.011
cellular ketone metabolic process GO:0042180 80 0.011
spermatid development GO:0007286 4 0.011
brain development GO:0007420 97 0.011
circadian sleep wake cycle sleep GO:0050802 2 0.011
regulation of cytokine production GO:0001817 232 0.011
peripheral nervous system development GO:0007422 2 0.011
positive regulation of kinase activity GO:0033674 204 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
cell type specific apoptotic process GO:0097285 125 0.011
cerebellum development GO:0021549 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 6 0.011
cellular response to ionizing radiation GO:0071479 32 0.011
oocyte differentiation GO:0009994 2 0.011
cytokine production GO:0001816 247 0.011
defense response to virus GO:0051607 71 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
positive regulation of wnt signaling pathway GO:0030177 54 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
regulation of cell differentiation GO:0045595 393 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
protein localization to organelle GO:0033365 280 0.011
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.011
Human
response to hormone GO:0009725 175 0.011
associative learning GO:0008306 1 0.010
positive regulation of cytokine production GO:0001819 167 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
negative regulation of cell growth GO:0030308 83 0.010
tissue morphogenesis GO:0048729 96 0.010
regulation of actin filament polymerization GO:0030833 50 0.010
circadian behavior GO:0048512 2 0.010
response to virus GO:0009615 126 0.010
protein targeting GO:0006605 187 0.010
nuclear transport GO:0051169 179 0.010
maintenance of location in cell GO:0051651 62 0.010
protein destabilization GO:0031648 12 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
macroautophagy GO:0016236 39 0.010
response to organic cyclic compound GO:0014070 204 0.010
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.010
negative regulation of transferase activity GO:0051348 124 0.010
centrosome cycle GO:0007098 32 0.010
innate immune response GO:0045087 178 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010

RNF38 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.034
eye and adnexa disease DOID:1492 150 0.034
nervous system disease DOID:863 431 0.034
eye disease DOID:5614 149 0.034
retinal disease DOID:5679 118 0.020
retinal degeneration DOID:8466 89 0.020
central nervous system disease DOID:331 186 0.019
cancer DOID:162 167 0.013
Human
disease of cellular proliferation DOID:14566 174 0.013
Human
organ system cancer DOID:0050686 164 0.013
Human
retinitis pigmentosa DOID:10584 51 0.011