Homo sapiens

48 known processes

NFYC

nuclear transcription factor Y, gamma

(Aliases: HAP5,NF-YC,DKFZp667G242,CBF-C,HSM,CBFC,FLJ45775,H1TF2A)

NFYC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of stem cell maintenance GO:2000036 4 0.452
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.364
regulation of mapk cascade GO:0043408 262 0.312
positive regulation of phosphorylation GO:0042327 394 0.264
signal transduction by phosphorylation GO:0023014 297 0.246
calcium ion transport GO:0006816 147 0.177
positive regulation of mapk cascade GO:0043410 190 0.165
cellular macromolecular complex assembly GO:0034622 324 0.165
regulation of stem cell differentiation GO:2000736 56 0.160
compound eye development GO:0048749 1 0.108
divalent inorganic cation transport GO:0072511 158 0.098
divalent metal ion transport GO:0070838 152 0.091
protein localization to organelle GO:0033365 280 0.080
cation transport GO:0006812 331 0.079
nuclear transport GO:0051169 179 0.079
trophectodermal cell differentiation GO:0001829 3 0.079
regulation of cell differentiation GO:0045595 393 0.078
regulation of metal ion transport GO:0010959 120 0.077
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.073
regulation of intracellular transport GO:0032386 195 0.073
intracellular protein transport GO:0006886 270 0.073
regulation of protein transport GO:0051223 213 0.070
negative regulation of programmed cell death GO:0043069 321 0.068
establishment of protein localization to organelle GO:0072594 172 0.068
viral process GO:0016032 146 0.067
negative regulation of cell death GO:0060548 345 0.066
negative regulation of transport GO:0051051 176 0.066
interspecies interaction between organisms GO:0044419 156 0.063
regulation of calcium ion transport GO:0051924 79 0.061
response to other organism GO:0051707 261 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
stem cell maintenance GO:0019827 19 0.059
protein targeting GO:0006605 187 0.058
regulation of cellular component biogenesis GO:0044087 281 0.056
cytoplasmic transport GO:0016482 379 0.056
multi organism cellular process GO:0044764 156 0.055
defense response to virus GO:0051607 71 0.055
negative regulation of protein metabolic process GO:0051248 391 0.054
negative regulation of apoptotic process GO:0043066 316 0.054
single organism membrane organization GO:0044802 268 0.053
protein dna complex subunit organization GO:0071824 80 0.053
negative regulation of developmental process GO:0051093 247 0.053
regulation of cell cycle GO:0051726 393 0.051
metal ion transport GO:0030001 272 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.050
negative regulation of catalytic activity GO:0043086 335 0.050
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.048
cellular amino acid metabolic process GO:0006520 116 0.048
cell development GO:0048468 328 0.048
Fly
maintenance of location GO:0051235 112 0.047
regulation of establishment of protein localization GO:0070201 242 0.046
negative regulation of protein transport GO:0051224 75 0.044
regulation of defense response GO:0031347 154 0.042
defense response GO:0006952 315 0.041
mapk cascade GO:0000165 288 0.040
stem cell differentiation GO:0048863 93 0.040
determination of adult lifespan GO:0008340 2 0.039
viral life cycle GO:0019058 132 0.038
cellular amine metabolic process GO:0044106 41 0.038
monocarboxylic acid metabolic process GO:0032787 185 0.038
regulation of protein import into nucleus GO:0042306 78 0.038
multicellular organismal aging GO:0010259 3 0.037
positive regulation of cell proliferation GO:0008284 301 0.036
nucleocytoplasmic transport GO:0006913 176 0.036
response to biotic stimulus GO:0009607 276 0.036
single organism cellular localization GO:1902580 332 0.036
positive regulation of immune system process GO:0002684 283 0.035
blastocyst formation GO:0001825 3 0.035
protein dna complex assembly GO:0065004 64 0.035
ion homeostasis GO:0050801 230 0.035
regulation of stem cell proliferation GO:0072091 15 0.034
bmp signaling pathway involved in heart development GO:0061312 3 0.034
negative regulation of multicellular organismal process GO:0051241 317 0.034
covalent chromatin modification GO:0016569 254 0.033
protein targeting to nucleus GO:0044744 104 0.033
positive regulation of locomotion GO:0040017 186 0.033
peptidyl lysine acetylation GO:0018394 101 0.033
stem cell development GO:0048864 69 0.032
protein modification by small protein removal GO:0070646 92 0.032
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.032
fatty acid metabolic process GO:0006631 115 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
response to lipid GO:0033993 206 0.031
negative regulation of cell differentiation GO:0045596 171 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.030
response to external biotic stimulus GO:0043207 261 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
establishment of viral latency GO:0019043 1 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
chromatin organization GO:0006325 351 0.029
chemical homeostasis GO:0048878 306 0.029
amine metabolic process GO:0009308 44 0.028
positive regulation of response to external stimulus GO:0032103 88 0.028
negative regulation of cellular amine metabolic process GO:0033239 3 0.028
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
regulation of protein complex assembly GO:0043254 147 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
regulation of mitotic cell cycle GO:0007346 189 0.027
regulation of defense response to virus GO:0050688 33 0.027
regulation of response to external stimulus GO:0032101 222 0.027
cation transmembrane transport GO:0098655 238 0.027
regulation of methylation dependent chromatin silencing GO:0090308 3 0.027
response to oxygen containing compound GO:1901700 369 0.026
internal peptidyl lysine acetylation GO:0018393 97 0.026
regulation of ion transport GO:0043269 189 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
regulation of cell development GO:0060284 161 0.026
nuclear import GO:0051170 106 0.026
embryonic camera type eye morphogenesis GO:0048596 2 0.026
negative regulation of proteolysis GO:0045861 132 0.026
ion transmembrane transport GO:0034220 338 0.025
protein catabolic process GO:0030163 325 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
protein import into nucleus GO:0006606 104 0.025
striated muscle contraction GO:0006941 52 0.025
regulation of intracellular protein transport GO:0033157 123 0.025
regulation of locomotion GO:0040012 329 0.024
dna templated transcription initiation GO:0006352 35 0.024
response to hormone GO:0009725 175 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
neural tube formation GO:0001841 3 0.024
cardiac muscle cell contraction GO:0086003 4 0.024
cellular lipid metabolic process GO:0044255 303 0.023
oogenesis GO:0048477 2 0.023
establishment of protein localization to membrane GO:0090150 121 0.023
single organism nuclear import GO:1902593 104 0.023
regulation of cytokine production GO:0001817 232 0.023
positive regulation of stem cell proliferation GO:2000648 10 0.023
mitotic cell cycle process GO:1903047 286 0.022
ras protein signal transduction GO:0007265 73 0.022
regulation of homeostatic process GO:0032844 121 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
response to metal ion GO:0010038 84 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
protein processing GO:0016485 226 0.021
regulation of multi organism process GO:0043900 157 0.021
lipid transport GO:0006869 90 0.021
histone acetylation GO:0016573 93 0.021
retrograde transport endosome to golgi GO:0042147 45 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
regulation of immune effector process GO:0002697 91 0.020
circulatory system development GO:0072359 262 0.020
cellular ketone metabolic process GO:0042180 80 0.020
organic acid biosynthetic process GO:0016053 97 0.020
immune effector process GO:0002252 159 0.020
lipid metabolic process GO:0006629 381 0.020
somatic stem cell maintenance GO:0035019 4 0.020
negative regulation of protein processing GO:0010955 142 0.020
defense response to other organism GO:0098542 129 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
modification of morphology or physiology of other organism GO:0035821 43 0.020
positive regulation of viral process GO:0048524 37 0.020
regulation of cell migration GO:0030334 289 0.020
heart development GO:0007507 95 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
actin mediated cell contraction GO:0070252 12 0.020
transmembrane transport GO:0055085 399 0.020
negative regulation of protein modification process GO:0031400 200 0.019
endosomal transport GO:0016197 129 0.019
morphogenesis of embryonic epithelium GO:0016331 4 0.019
sex determination GO:0007530 3 0.019
protein oligomerization GO:0051259 173 0.019
negative regulation of intracellular transport GO:0032387 60 0.019
regulation of mitotic cell cycle phase transition GO:1901990 118 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
positive regulation of cell death GO:0010942 263 0.019
cell projection organization GO:0030030 252 0.019
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
regulation of protein localization GO:0032880 296 0.019
response to drug GO:0042493 81 0.019
actin filament based movement GO:0030048 17 0.018
spinal cord development GO:0021510 4 0.018
cell cycle phase transition GO:0044770 173 0.018
vesicle organization GO:0016050 62 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
protein import GO:0017038 130 0.018
apoptotic signaling pathway GO:0097190 268 0.018
peripheral nervous system development GO:0007422 2 0.018
internal protein amino acid acetylation GO:0006475 101 0.018
epithelium development GO:0060429 227 0.017
regulation of protein targeting GO:1903533 91 0.017
peptidyl lysine modification GO:0018205 144 0.017
protein deubiquitination GO:0016579 79 0.017
tube closure GO:0060606 3 0.017
post embryonic development GO:0009791 2 0.017
Worm
oxidation reduction process GO:0055114 396 0.017
Yeast
negative regulation of protein maturation GO:1903318 142 0.017
specification of organ identity GO:0010092 3 0.017
regulation of protein processing GO:0070613 150 0.017
innate immune response GO:0045087 178 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
positive regulation of protein complex assembly GO:0031334 86 0.017
regulation of cellular component movement GO:0051270 334 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
positive regulation of cholesterol storage GO:0010886 4 0.016
activation of immune response GO:0002253 114 0.016
erk1 and erk2 cascade GO:0070371 104 0.016
positive regulation of viral entry into host cell GO:0046598 3 0.016
regulation of secretion GO:0051046 194 0.016
memory GO:0007613 3 0.016
cellular protein complex assembly GO:0043623 188 0.016
regulation of response to biotic stimulus GO:0002831 55 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
metencephalon development GO:0022037 2 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.015
anion transport GO:0006820 161 0.015
cellular cation homeostasis GO:0030003 163 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
translation GO:0006412 132 0.015
cell growth GO:0016049 160 0.015
central nervous system development GO:0007417 123 0.015
positive regulation of cytokine production GO:0001819 167 0.015
protein localization to nucleus GO:0034504 136 0.015
actin filament based process GO:0030029 224 0.015
membrane organization GO:0061024 292 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of cell growth GO:0001558 135 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
hemopoiesis GO:0030097 180 0.015
regulation of behavior GO:0050795 82 0.015
cytokine production GO:0001816 247 0.015
somitogenesis GO:0001756 2 0.015
negative regulation of mitotic cell cycle GO:0045930 102 0.015
positive regulation of ion transport GO:0043270 87 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
regulation of growth GO:0040008 165 0.014
protein acylation GO:0043543 138 0.014
response to nitrogen compound GO:1901698 184 0.014
primary neural tube formation GO:0014020 3 0.014
neuromuscular junction development GO:0007528 3 0.014
bmp signaling pathway involved in heart induction GO:0003130 3 0.014
multi organism metabolic process GO:0044033 41 0.014
regulation of transmembrane transport GO:0034762 139 0.014
nucleotide catabolic process GO:0009166 408 0.014
tissue morphogenesis GO:0048729 96 0.014
small molecule biosynthetic process GO:0044283 157 0.014
thymus development GO:0048538 3 0.014
protein maturation GO:0051604 233 0.014
heart formation GO:0060914 2 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
locomotory behavior GO:0007626 1 0.014
protein localization to membrane GO:0072657 160 0.014
regulation of immune response GO:0050776 201 0.014
anatomical structure homeostasis GO:0060249 100 0.014
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.014
trabecula morphogenesis GO:0061383 2 0.014
cardiac muscle contraction GO:0060048 34 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
lens development in camera type eye GO:0002088 2 0.013
viral gene expression GO:0019080 35 0.013
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
regulation of transferase activity GO:0051338 355 0.013
response to topologically incorrect protein GO:0035966 29 0.013
sensory perception of pain GO:0019233 4 0.013
associative learning GO:0008306 1 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
protein acetylation GO:0006473 116 0.013
release from viral latency GO:0019046 1 0.013
regeneration GO:0031099 4 0.013
mating GO:0007618 1 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
endomembrane system organization GO:0010256 196 0.013
cell differentiation in spinal cord GO:0021515 1 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
positive regulation of lipid storage GO:0010884 10 0.013
regulation of transcription factor import into nucleus GO:0042990 39 0.013
lipid homeostasis GO:0055088 39 0.012
ventral spinal cord interneuron differentiation GO:0021514 1 0.012
negative regulation of gene silencing by mirna GO:0060965 3 0.012
response to endoplasmic reticulum stress GO:0034976 49 0.012
purine containing compound catabolic process GO:0072523 411 0.012
regulation of actin filament based process GO:0032970 141 0.012
response to axon injury GO:0048678 1 0.012
regulation of kinase activity GO:0043549 314 0.012
organ formation GO:0048645 3 0.012
maintenance of location in cell GO:0051651 62 0.012
regulation of protein kinase activity GO:0045859 289 0.012
oocyte development GO:0048599 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
cellular response to nutrient levels GO:0031669 69 0.012
Yeast
response to low density lipoprotein particle GO:0055098 4 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
cellular component disassembly GO:0022411 92 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
response to radiation GO:0009314 151 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
dephosphorylation GO:0016311 209 0.012
response to virus GO:0009615 126 0.012
endodermal mesodermal cell signaling involved in heart induction GO:0003134 3 0.012
regulation of organ formation GO:0003156 4 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
hindbrain development GO:0030902 3 0.012
positive regulation of calcium ion transport GO:0051928 51 0.012
citrate metabolic process GO:0006101 2 0.012
immune response GO:0006955 307 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
regulation of cell cycle process GO:0010564 266 0.012
neurogenesis GO:0022008 169 0.012
Fly
regulation of protein catabolic process GO:0042176 155 0.012
spermatid differentiation GO:0048515 4 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
female gamete generation GO:0007292 2 0.012
regulation of protein secretion GO:0050708 86 0.012
hippocampus development GO:0021766 1 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of secretion by cell GO:1903530 177 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
maintenance of protein location GO:0045185 57 0.012
myoblast fusion GO:0007520 1 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
biological adhesion GO:0022610 331 0.011
tissue regeneration GO:0042246 3 0.011
pituitary gland development GO:0021983 2 0.011
negative regulation of viral process GO:0048525 66 0.011
cell cycle checkpoint GO:0000075 117 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
Yeast
negative regulation of calcium ion transport GO:0051926 19 0.011
cell chemotaxis GO:0060326 112 0.011
protein stabilization GO:0050821 64 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
positive regulation of organelle organization GO:0010638 195 0.011
cellular response to external stimulus GO:0071496 111 0.011
Yeast
stem cell proliferation GO:0072089 25 0.011
rhythmic behavior GO:0007622 2 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of tumor necrosis factor production GO:0032680 43 0.011
regulation of interleukin 2 secretion GO:1900040 2 0.011
system process GO:0003008 349 0.011
mitotic cell cycle GO:0000278 326 0.011
histone modification GO:0016570 251 0.011
negative regulation of secretion GO:0051048 58 0.011
limbic system development GO:0021761 3 0.011
cellular protein catabolic process GO:0044257 261 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
negative regulation of calcium ion import GO:0090281 1 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
nucleoside catabolic process GO:0009164 408 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
interaction with symbiont GO:0051702 26 0.011
cerebellum development GO:0021549 2 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
cholesterol homeostasis GO:0042632 28 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
embryonic eye morphogenesis GO:0048048 2 0.011
activation of innate immune response GO:0002218 55 0.011
secretion by cell GO:0032940 226 0.011
ventral spinal cord development GO:0021517 1 0.011
regulation of innate immune response GO:0045088 97 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 412 0.010
regulation of intracellular transport of viral material GO:1901252 2 0.010
positive regulation of cell migration GO:0030335 172 0.010
response to abiotic stimulus GO:0009628 336 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
organophosphate catabolic process GO:0046434 430 0.010
negative regulation of immune response GO:0050777 40 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
tissue homeostasis GO:0001894 63 0.010
dicarboxylic acid metabolic process GO:0043648 29 0.010
myeloid cell differentiation GO:0030099 117 0.010
blastocyst development GO:0001824 3 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.010
negative regulation of cytoplasmic transport GO:1903650 46 0.010
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
positive regulation of defense response GO:0031349 87 0.010
neurotransmitter secretion GO:0007269 4 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
leukocyte migration GO:0050900 107 0.010
regulation of chemotaxis GO:0050920 74 0.010
positive regulation of protein transport GO:0051222 135 0.010

NFYC disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.040
sensory system disease DOID:0050155 203 0.016
eye and adnexa disease DOID:1492 150 0.016
nervous system disease DOID:863 431 0.016
eye disease DOID:5614 149 0.014
inherited metabolic disorder DOID:655 242 0.014
musculoskeletal system disease DOID:17 223 0.014
cardiovascular system disease DOID:1287 106 0.012
retinal disease DOID:5679 118 0.012
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
acquired metabolic disease DOID:0060158 58 0.012
central nervous system disease DOID:331 186 0.012
muscular disease DOID:0080000 114 0.010